Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hexokinase | 0.1527 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0485 | 0.3128 | 0.3128 |
Onchocerca volvulus | 0.1527 | 1 | 1 | |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0039 | 0.0183 | 0.0183 |
Leishmania major | hexokinase, putative | 0.1527 | 1 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0039 | 0.0183 | 0.0183 |
Plasmodium falciparum | hexokinase | 0.1527 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase type II | 0.1527 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.1527 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.0472 | 0.3043 | 0.3043 |
Onchocerca volvulus | 0.1527 | 1 | 1 | |
Schistosoma mansoni | voltage-gated potassium channel | 0.0043 | 0.0207 | 0.0207 |
Brugia malayi | Hexokinase family protein | 0.1527 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.1527 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1527 | 1 | 0.5 |
Brugia malayi | hexokinase type II | 0.0485 | 0.3128 | 0.3128 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0039 | 0.0183 | 0.0183 |
Echinococcus multilocularis | hexokinase | 0.1527 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.1527 | 1 | 1 |
Entamoeba histolytica | hexokinase 2 | 0.1527 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0472 | 0.3043 | 0.3043 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0043 | 0.0207 | 0.0207 |
Loa Loa (eye worm) | hexokinase | 0.0958 | 0.6246 | 0.6246 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0149 | 0.0149 |
Plasmodium vivax | hexokinase, putative | 0.1527 | 1 | 0.5 |
Onchocerca volvulus | 0.1527 | 1 | 1 | |
Loa Loa (eye worm) | hexokinase | 0.1527 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1041 | 0.6797 | 0.6797 |
Brugia malayi | Hexokinase family protein | 0.0958 | 0.6246 | 0.6246 |
Echinococcus granulosus | hexokinase type 2 | 0.1527 | 1 | 1 |
Trypanosoma brucei | hexokinase, putative | 0.1527 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.1527 | 1 | 0.5 |
Schistosoma mansoni | hexokinase | 0.1527 | 1 | 1 |
Echinococcus multilocularis | hexokinase type 2 | 0.1527 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.1527 | 1 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0039 | 0.0183 | 0.0183 |
Leishmania major | hexokinase, putative | 0.1527 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0166 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1527 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.1527 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0036 | 0.0166 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.1527 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.1527 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0485 | 0.3128 | 0.3128 |
Echinococcus granulosus | hexokinase | 0.1527 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.1527 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.