Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.057 | 0.3133 | 0.3133 |
Trypanosoma cruzi | hexokinase, putative | 0.1794 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.1794 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1223 | 0.6799 | 0.6799 |
Loa Loa (eye worm) | hexokinase | 0.1125 | 0.6248 | 0.6248 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0042 | 0.0168 | 0.0168 |
Leishmania major | hexokinase, putative | 0.1794 | 1 | 0.5 |
Echinococcus granulosus | hexokinase type 2 | 0.1794 | 1 | 1 |
Trypanosoma cruzi | hexokinase, putative | 0.1794 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.1794 | 1 | 1 |
Leishmania major | hexokinase, putative | 0.1794 | 1 | 0.5 |
Plasmodium falciparum | hexokinase | 0.1794 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.057 | 0.3133 | 0.3133 |
Plasmodium vivax | hexokinase, putative | 0.1794 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0555 | 0.3047 | 0.3047 |
Schistosoma mansoni | hexokinase | 0.1794 | 1 | 1 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0042 | 0.0168 | 0.0168 |
Trypanosoma brucei | hexokinase | 0.1794 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0137 | 0.0137 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0046 | 0.0189 | 0.0189 |
Onchocerca volvulus | 0.1794 | 1 | 1 | |
Onchocerca volvulus | 0.1794 | 1 | 1 | |
Echinococcus multilocularis | hexokinase | 0.1794 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.1794 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.1794 | 1 | 1 |
Onchocerca volvulus | 0.1794 | 1 | 1 | |
Brugia malayi | Hexokinase family protein | 0.1125 | 0.6248 | 0.6248 |
Brugia malayi | hexokinase type II | 0.057 | 0.3133 | 0.3133 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.0152 | 0.5 |
Echinococcus multilocularis | hexokinase type 2 | 0.1794 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0042 | 0.0168 | 0.0168 |
Echinococcus granulosus | hexokinase | 0.1794 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.1794 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.1794 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0042 | 0.0168 | 0.0168 |
Brugia malayi | Hexokinase family protein | 0.0555 | 0.3047 | 0.3047 |
Trypanosoma brucei | hexokinase | 0.1794 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 2 | 0.1794 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.0152 | 0.5 |
Echinococcus granulosus | hexokinase | 0.1794 | 1 | 1 |
Loa Loa (eye worm) | hexokinase type II | 0.1794 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0046 | 0.0189 | 0.0189 |
Treponema pallidum | hexokinase (hxk) | 0.1794 | 1 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.1794 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.1794 | 1 | 1 |
Trypanosoma brucei | hexokinase, putative | 0.1794 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.