Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0535 | 0.4176 | 0.3437 |
Onchocerca volvulus | 0.0535 | 0.4176 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.0535 | 0.4176 | 0.4176 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0535 | 0.4176 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0535 | 0.4176 | 0.3437 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0366 | 0.1329 | 0.3182 |
Echinococcus granulosus | cathepsin l1 | 0.0535 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0881 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0881 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0366 | 0.1329 | 0.1329 |
Onchocerca volvulus | 0.0535 | 0.4176 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0354 | 0.1126 | 0.5 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0535 | 0.4176 | 0.3437 |
Echinococcus multilocularis | cathepsin b | 0.0881 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0535 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cathepsin b | 0.0881 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0535 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0535 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0535 | 0.4176 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0354 | 0.1126 | 0.1126 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0535 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0354 | 0.1126 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0535 | 0.4176 | 1 |
Onchocerca volvulus | 0.0535 | 0.4176 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0354 | 0.1126 | 0.5 |
Plasmodium vivax | vivapain-2 | 0.0535 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0366 | 0.1329 | 0.3182 |
Loa Loa (eye worm) | ctsf protein | 0.0535 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0354 | 0.1126 | 0.2697 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.0535 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0535 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0535 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin b | 0.0881 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0881 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0881 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0881 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0366 | 0.1329 | 0.1329 |
Echinococcus granulosus | cathepsin b | 0.0881 | 1 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0535 | 0.4176 | 0.3437 |
Brugia malayi | cathepsin L-like precursor | 0.0366 | 0.1329 | 0.1329 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0535 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0535 | 0.4176 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 0.1329 | 0.0228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0535 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0535 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0535 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0535 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0535 | 0.4176 | 0.3437 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0366 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0366 | 0.1329 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0881 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Onchocerca volvulus | 0.0535 | 0.4176 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0354 | 0.1126 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0535 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Onchocerca volvulus | 0.0535 | 0.4176 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0354 | 0.1126 | 0.1126 |
Entamoeba histolytica | cysteine protease, putative | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0535 | 0.4176 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 0.1329 | 0.0228 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0535 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0535 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0535 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0535 | 0.4176 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0535 | 0.4176 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0535 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0366 | 0.1329 | 0.1329 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0366 | 0.1329 | 0.1329 |
Loa Loa (eye worm) | hypothetical protein | 0.0366 | 0.1329 | 0.0228 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0535 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0366 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0535 | 0.4176 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.