Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | chromobox protein 1 | 0.0067 | 0.1839 | 0.1839 |
Brugia malayi | hypothetical protein | 0.0085 | 0.2865 | 0.2865 |
Brugia malayi | Heterochromatin protein 1 | 0.0067 | 0.1839 | 0.1839 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0302 | 0.1644 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0035 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0209 | 1 | 1 |
Schistosoma mansoni | eyes absent homolog | 0.0085 | 0.2865 | 0.2865 |
Echinococcus multilocularis | acetylcholinesterase | 0.0209 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0137 | 0.0137 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0035 | 0 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0302 | 0.1644 |
Trichomonas vaginalis | chromobox protein, putative | 0.0067 | 0.1839 | 1 |
Echinococcus granulosus | geminin | 0.0164 | 0.7385 | 0.7385 |
Echinococcus multilocularis | geminin | 0.0164 | 0.7385 | 0.7385 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0137 | 0.0137 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0035 | 0 | 0.5 |
Echinococcus multilocularis | chromobox protein 1 | 0.0067 | 0.1839 | 0.1839 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0035 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.2865 | 0.2865 |
Echinococcus multilocularis | acetylcholinesterase | 0.0209 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0137 | 0.0747 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0137 | 0.0747 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0209 | 1 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0067 | 0.1839 | 0.1839 |
Echinococcus granulosus | chromobox protein 1 | 0.0067 | 0.1839 | 0.1839 |
Loa Loa (eye worm) | carboxylesterase | 0.0209 | 1 | 1 |
Schistosoma mansoni | chromobox protein | 0.0067 | 0.1839 | 0.1839 |
Trichomonas vaginalis | chromobox protein, putative | 0.0067 | 0.1839 | 1 |
Schistosoma mansoni | chromobox protein | 0.0067 | 0.1839 | 0.1839 |
Echinococcus granulosus | acetylcholinesterase | 0.0209 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0209 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0209 | 1 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0137 | 0.4548 |
Echinococcus granulosus | carboxylesterase 5A | 0.0209 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.7385 | 0.7385 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.7385 | 0.7385 |
Brugia malayi | Carboxylesterase family protein | 0.0209 | 1 | 1 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0067 | 0.1839 | 0.1839 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0302 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.2865 | 0.2865 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.