Detailed information for compound 894720

Basic information

Technical information
  • TDR Targets ID: 894720
  • Name: 3-nitro-N-[4-(phenylamino)phenyl]benzenesulfo namide
  • MW: 369.394 | Formula: C18H15N3O4S
  • H donors: 2 H acceptors: 4 LogP: 3.82 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-][N+](=O)c1cccc(c1)S(=O)(=O)Nc1ccc(cc1)Nc1ccccc1
  • InChi: 1S/C18H15N3O4S/c22-21(23)17-7-4-8-18(13-17)26(24,25)20-16-11-9-15(10-12-16)19-14-5-2-1-3-6-14/h1-13,19-20H
  • InChiKey: VDYNULSQWSGVBS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • CBMicro_011516
  • ZINC04957258
  • AG-690/15431426
  • BIM-0011502.P001

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) 0.0384 0.2725 1
Schistosoma mansoni microtubule-associated protein tau 0.068 0.4954 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0042 0.0035
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0025 0.0026 0.0003
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0054 0.0059
Schistosoma mansoni protein arginine N-methyltransferase 1 0.003 0.0063 0.0077
Echinococcus multilocularis histone arginine methyltransferase CARMER 0.0142 0.0909 0.1793
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0116 0.0713 1
Onchocerca volvulus 0.0166 0.1083 0.1061
Mycobacterium ulcerans spermidine synthase 0.0384 0.2725 0.887
Echinococcus multilocularis protein arginine N methyltransferase 8 0.003 0.0063 0.0077
Loa Loa (eye worm) hypothetical protein 0.0075 0.0403 0.0414
Echinococcus multilocularis purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Entamoeba histolytica hypothetical protein 0.0058 0.0275 0.3634
Echinococcus multilocularis microtubule associated protein 2 0.068 0.4954 1
Plasmodium vivax SET domain protein, putative 0.0125 0.0777 0.1974
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0078 0.0425 1
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0078 0.0425 1
Echinococcus granulosus histone h3 methyltransferase 0.0126 0.0788 0.1548
Schistosoma mansoni cpg binding protein 0.0095 0.0554 0.1074
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0028 0.0049 0.0065
Echinococcus multilocularis purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.01 0.0153
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0116 0.0713 0.1397
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0078 0.0425 0.582
Toxoplasma gondii DNA methyltransferase 2, putative 0.0116 0.0713 0.6523
Brugia malayi jmjC domain containing protein 0.0037 0.0112 0.0123
Loa Loa (eye worm) SET domain-containing protein 0.0195 0.1301 0.1399
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0078 0.0425 0.0465
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0183 0.1216 0.2417
Echinococcus multilocularis uridine phosphorylase 1 0.0078 0.0425 0.0813
Loa Loa (eye worm) Carm1-pending protein 0.0142 0.0909 0.0969
Echinococcus multilocularis peregrin 0.0054 0.0243 0.0442
Brugia malayi Histone-lysine N-methyltransferase, H3 lysine-79 specific 0.0126 0.0788 0.0861
Loa Loa (eye worm) hypothetical protein 0.0033 0.0086 0.0067
Echinococcus granulosus histone lysine methyltransferase setb 0.0183 0.1216 0.2417
Brugia malayi Pre-SET motif family protein 0.1237 0.9145 1
Echinococcus granulosus histone arginine methyltransferase CARMER 0.0142 0.0909 0.1793
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0054 0.006
Trypanosoma brucei spermidine synthase 0.0515 0.3716 1
Loa Loa (eye worm) hypothetical protein 0.0166 0.1083 0.1161
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0231 0.1572 0.3138
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0058 0.0275 0.0678
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0425 0.0379
Brugia malayi Disco-interacting protein 2 homolog 0.0075 0.0403 0.044
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0112 0.0177
Echinococcus granulosus protein arginine methyltransferase 0.003 0.0063 0.0077
Entamoeba histolytica arginine N-methyltransferase 1, putative 0.0028 0.0049 0.0348
Brugia malayi hypothetical protein 0.0025 0.0025 0.0027
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0078 0.0425 1
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.003 0.0063 0.0014
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0423 0.3018 0.8109
Leishmania major S-adenosylmethionine decarboxylase 0.0417 0.2977 0.7998
Loa Loa (eye worm) hypothetical protein 0.0166 0.1083 0.1161
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Trypanosoma cruzi spermidine synthase, putative 0.0515 0.3716 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0275 0.0274
Plasmodium vivax histone-lysine N-methyltransferase, putative 0.0081 0.0443 0.1063
Plasmodium falciparum spermidine synthase 0.0515 0.3716 1
Onchocerca volvulus 0.0114 0.0696 0.0673
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.003 0.0063 0.0014
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0116 0.0713 0.1397
Echinococcus multilocularis histone h3 methyltransferase 0.0126 0.0788 0.1548
Toxoplasma gondii hypothetical protein 0.0165 0.108 1
Echinococcus multilocularis jumonji domain containing protein 0.004 0.014 0.0233
Schistosoma mansoni hypothetical protein 0.0168 0.1102 0.2186
Schistosoma mansoni hypothetical protein 0.0029 0.0054 0.006
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0078 0.0425 0.582
Toxoplasma gondii histone lysine methyltransferase SET1 0.0064 0.0321 0.2811
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0078 0.0425 0.0379
Schistosoma mansoni cpg binding protein 0.0095 0.0554 0.1074
Schistosoma mansoni protein arginine N-methyltransferase 1 0.003 0.0063 0.0077
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0027 0.0038 0.0027
Plasmodium vivax protein arginine N-methyltransferase 1, putative 0.003 0.0063 0.0023
Brugia malayi S-adenosylmethionine decarboxylase proenzyme 0.0417 0.2977 0.3255
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0078 0.0425 0.0379
Echinococcus granulosus protein arginine N methyltransferase 8 0.003 0.0063 0.0077
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0417 0.2977 0.7998
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0078 0.0425 0.582
Echinococcus multilocularis cpg binding protein 0.0095 0.0554 0.1074
Schistosoma mansoni protein arginine N-methyltransferase 1 0.003 0.0063 0.0077
Onchocerca volvulus 0.0231 0.1572 0.1551
Onchocerca volvulus 0.0094 0.0542 0.0518
Schistosoma mansoni histone J3 methyltransferase 0.0126 0.0788 0.1548
Echinococcus granulosus protein arginine N methyltransferase 7 0.0028 0.0049 0.0049
Brugia malayi SET domain containing protein 0.0195 0.1301 0.1422
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0112 0.0177
Echinococcus multilocularis purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Leishmania major modification methylase-like protein 0.0116 0.0713 0.1865
Trichomonas vaginalis protein arginine N-methyltransferase, putative 0.003 0.0063 0.0014
Schistosoma mansoni methylthioadenosine phosphorylase 0.0423 0.3018 0.6072
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0286 0.0287
Brugia malayi MTAP 0.0423 0.3018 0.33
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0071 0.037 0.07
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0403 0.0768
Brugia malayi uridine phosphorylase family protein 0.0078 0.0425 0.0465
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0027 0.0038 0.0027
Brugia malayi Protein arginine N-methyltransferase 0.0028 0.0049 0.0053
Schistosoma mansoni hypothetical protein 0.0028 0.0049 0.0049
Chlamydia trachomatis AMP nucleosidase 0.0078 0.0425 0.5
Treponema pallidum pfs protein (pfs) 0.0078 0.0425 0.5
Toxoplasma gondii bicoid-interacting protein BIN3 0.0028 0.0049 0.0227
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0183 0.1216 0.2417
Echinococcus granulosus histone lysine N methyltransferase H3 lysine 36 0.0036 0.0111 0.0175
Echinococcus granulosus S adenosylmethionine decarboxylase proenzyme 0.0417 0.2977 0.5989
Mycobacterium leprae probable uridine phosphorylase 0.0078 0.0425 0.5
Leishmania major spermidine synthase 0.0515 0.3716 1
Entamoeba histolytica arginine N-methyltransferase protein, putative 0.0058 0.0275 0.3634
Brugia malayi Spermidine synthase 0.0515 0.3716 0.4063
Loa Loa (eye worm) NNMT/PNMT/TEMT family protein 0.0881 0.6463 0.7059
Echinococcus granulosus peregrin 0.0054 0.0243 0.0442
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0279
Giardia lamblia UPL-1 0.0078 0.0425 1
Loa Loa (eye worm) hypothetical protein 0.0166 0.1083 0.1161
Loa Loa (eye worm) hypothetical protein 0.0183 0.1216 0.1306
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0116 0.0713 0.6523
Schistosoma mansoni purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Trypanosoma cruzi spermidine synthase, putative 0.0515 0.3716 1
Trypanosoma cruzi S-adenosylmethionine decarboxylase proenzyme, putative 0.0417 0.2977 0.7998
Loa Loa (eye worm) hypothetical protein 0.0881 0.6463 0.7059
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0112 0.0177
Loa Loa (eye worm) hypothetical protein 0.0126 0.0788 0.0837
Plasmodium falciparum protein arginine N-methyltransferase 1 0.003 0.0063 0.0023
Trypanosoma cruzi protein arginine n-methyltransferase 7 0.0028 0.0049 0.0065
Echinococcus granulosus DNA methyltransferase 2, putative 0.0116 0.0713 0.1397
Brugia malayi hypothetical protein 0.0166 0.1083 0.1184
Echinococcus multilocularis S adenosylmethionine decarboxylase proenzyme 0.0417 0.2977 0.5989
Schistosoma mansoni suppressor of variegation 4-20-related 0.0132 0.0831 0.1636
Trypanosoma cruzi arginine N-methyltransferase, type III 0.0028 0.0049 0.0065
Loa Loa (eye worm) protein arginine N-methyltransferase 0.0028 0.0049 0.0026
Plasmodium vivax S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative 0.0203 0.1366 0.3582
Leishmania major methylthioadenosine phosphorylase, putative 0.0423 0.3018 0.8109
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0078 0.0425 0.582
Echinococcus granulosus geminin 0.0168 0.1102 0.2186
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0078 0.0425 0.1014
Schistosoma mansoni uridine phosphorylase 0.0078 0.0425 0.0813
Leishmania major arginine N-methyltransferase, type I 0.0028 0.0049 0.0065
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0078 0.0425 0.0379
Brugia malayi Carm1-pending protein 0.0142 0.0909 0.0993
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0078 0.0425 0.5
Trypanosoma brucei protein arginine n-methyltransferase 7 0.0028 0.0049 0.0065
Trypanosoma brucei Protein arginine N-methyltransferase 1 catalytic subunit 0.0058 0.0275 0.0678
Echinococcus multilocularis purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Echinococcus granulosus histone lysine n methyltransferase suv420h1 0.0132 0.0831 0.1636
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0116 0.0713 0.18
Brugia malayi SET domain containing protein 0.0117 0.0717 0.0784
Echinococcus multilocularis histone lysine n methyltransferase setb1 0.0033 0.0086 0.0124
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0417 0.2977 0.7998
Echinococcus multilocularis purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Trypanosoma brucei S-adenosylmethionine decarboxylase proenzyme, putative 0.0417 0.2977 0.7998
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0054 0.0032
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0078 0.0425 0.0379
Plasmodium falciparum S-adenosylmethionine decarboxylase/ornithine decarboxylase 0.0203 0.1366 0.3582
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0078 0.0425 0.1085
Schistosoma mansoni hypothetical protein 0.0051 0.022 0.0396
Brugia malayi NNMT/PNMT/TEMT family protein 0.0881 0.6463 0.7067
Plasmodium vivax spermidine synthase, putative 0.0515 0.3716 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0026 0.0003
Schistosoma mansoni enhancer of zeste ezh 0.0195 0.1301 0.2589
Echinococcus granulosus methyl CpG binding domain protein 2 0.0025 0.0026 0.0003
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0125 0.0777 0.1526
Echinococcus granulosus jumonji domain containing protein 0.004 0.014 0.0233
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0078 0.0425 0.1085
Plasmodium falciparum purine nucleoside phosphorylase 0.0078 0.0425 0.1014
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0116 0.0713 0.18
Echinococcus multilocularis spermidine synthase 0.0515 0.3716 0.7488
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0078 0.0425 0.0379
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0078 0.0425 0.0379
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0032
Loa Loa (eye worm) CXXC zinc finger family protein 0.0094 0.0542 0.0567
Mycobacterium tuberculosis Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) 0.0344 0.2429 0.8712
Toxoplasma gondii histone arginine methyltransferase PRMT3 0.0028 0.0049 0.0227
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0203
Echinococcus multilocularis histone lysine N methyltransferase, H3 lysine 36 0.0036 0.0111 0.0175
Echinococcus multilocularis histone lysine N methyltransferase E(z) 0.0195 0.1301 0.2589
Schistosoma mansoni methylthioadenosine phosphorylase 0.0423 0.3018 0.6072
Loa Loa (eye worm) hypothetical protein 0.0025 0.0026 0.0001
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0078 0.0425 0.1085
Trypanosoma brucei uridine phosphorylase 0.0078 0.0425 0.1085
Echinococcus granulosus microtubule associated protein 2 0.068 0.4954 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0147 0.094 0.1858
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0183 0.1216 0.2417
Schistosoma mansoni SET domain protein 0.0038 0.0123 0.0199
Echinococcus multilocularis purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Echinococcus multilocularis histone lysine n methyltransferase suv420h1 0.0132 0.0831 0.1636
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0054 0.006
Toxoplasma gondii Purine nucleoside phosphorylase 0.0078 0.0425 0.3796
Loa Loa (eye worm) S-adenosylmethionine decarboxylase proenzyme 0.0417 0.2977 0.3236
Brugia malayi jmjC domain containing protein 0.0095 0.055 0.0601
Schistosoma mansoni methylthioadenosine phosphorylase 0.0078 0.0425 0.0813
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0423 0.3018 0.8109
Echinococcus multilocularis disco interacting protein 2 0.0075 0.0403 0.0766
Trypanosoma cruzi arginine N-methyltransferase, type I 0.0028 0.0049 0.0065
Brugia malayi Bromodomain containing protein 0.0027 0.0038 0.0042
Echinococcus multilocularis protein arginine methyltransferase 0.003 0.0063 0.0077
Echinococcus multilocularis geminin 0.0168 0.1102 0.2186
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0165 0.108 0.2802
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Toxoplasma gondii phosphorylase family protein 0.0078 0.0425 0.3796
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.055 0.1065
Leishmania major arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 0.0028 0.0049 0.0065
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0112 0.0096
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0054 0.006
Loa Loa (eye worm) spermidine synthase 0.0515 0.3716 0.4047
Echinococcus granulosus SET and MYND domain containing protein 3 0.0069 0.0357 0.0674
Loa Loa (eye worm) hypothetical protein 0.0106 0.0631 0.0665
Schistosoma mansoni cpg binding protein 0.0094 0.0542 0.1049
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0078 0.0425 0.0379
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0423 0.3018 0.3281
Trypanosoma cruzi spermidine synthase, putative 0.0515 0.3716 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0054 0.0279
Echinococcus granulosus methyltransferase protein 5 0.0028 0.0049 0.0049
Brugia malayi CXXC zinc finger family protein 0.0094 0.0542 0.0592
Trichomonas vaginalis set domain proteins, putative 0.135 1 1
Trypanosoma cruzi arginine N-methyltransferase, putative 0.0058 0.0275 0.0678
Brugia malayi Bromodomain containing protein 0.0029 0.0054 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.0078 0.0425 0.0379
Onchocerca volvulus Alhambra homolog 0.0029 0.0054 0.003
Echinococcus granulosus disco interacting protein 2 0.0075 0.0403 0.0766
Loa Loa (eye worm) hypothetical protein 0.0109 0.0654 0.0689
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0078 0.0425 0.5
Echinococcus multilocularis SET and MYND domain containing protein 3 0.0069 0.0357 0.0674
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0078 0.0425 0.0379
Leishmania major arginine N-methyltransferase-like protein 0.003 0.0063 0.0102
Loa Loa (eye worm) hypothetical protein 0.0881 0.6463 0.7059
Brugia malayi Pre-SET motif family protein 0.0158 0.1027 0.1123
Brugia malayi hypothetical protein 0.0058 0.0275 0.0301
Echinococcus granulosus histone lysine N methyltransferase Ez 0.0195 0.1301 0.2589
Trypanosoma cruzi spermidine synthase, putative 0.0515 0.3716 1
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0075 0.0403 0.0766
Toxoplasma gondii histone arginine methyltransferase PRMT4/CARM1 0.0142 0.0909 0.8375
Loa Loa (eye worm) hypothetical protein 0.0067 0.0344 0.035
Leishmania major nucleoside phosphorylase-like protein 0.0078 0.0425 0.1085
Echinococcus granulosus spermidine synthase 0.0515 0.3716 0.7488
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0423 0.3018 0.8109
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0423 0.3018 0.6072
Loa Loa (eye worm) uridine phosphorylase 0.0078 0.0425 0.0439
Toxoplasma gondii histone arginine methyltransferase PRMT1 0.003 0.0063 0.0358
Echinococcus multilocularis protein arginine N methyltransferase 7 0.0028 0.0049 0.0049
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0078 0.0425 0.582
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.055 0.1065
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0125 0.0777 0.1526
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0116 0.0713 0.1865
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0423 0.3018 1
Plasmodium falciparum histone-lysine N-methyltransferase, putative 0.0081 0.0443 0.1063
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0078 0.0425 0.0402
Brugia malayi PWWP domain containing protein 0.0025 0.0025 0.0027
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0078 0.0425 0.582
Brugia malayi SET domain containing protein 0.0132 0.0831 0.0909
Brugia malayi hypothetical protein 0.0025 0.0025 0.0027
Loa Loa (eye worm) SET domain-containing protein 0.0132 0.0831 0.0884
Schistosoma mansoni hypothetical protein 0.0168 0.1102 0.2186
Schistosoma mansoni protein arginine n-methyltransferase 0.0142 0.0909 0.1793
Schistosoma mansoni methyl-cpg binding protein mbd 0.0025 0.0026 0.0003
Entamoeba histolytica hypothetical protein 0.0078 0.0425 0.582
Echinococcus granulosus methylthioadenosine phosphorylase 0.0423 0.3018 0.6072
Trypanosoma brucei S-adenosylmethionine decarboxylase 0.0417 0.2977 0.7998
Brugia malayi PHD-finger family protein 0.0029 0.0054 0.0059
Echinococcus granulosus cpg binding protein 0.0095 0.0554 0.1074
Echinococcus granulosus histone lysine n methyltransferase setb1 0.0033 0.0086 0.0124
Schistosoma mansoni uridine phosphorylase 0.0078 0.0425 0.0813
Brugia malayi hypothetical protein 0.0166 0.1083 0.1184
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Toxoplasma gondii phosphorylase family protein 0.0078 0.0425 0.3796
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1237 0.9145 1
Treponema pallidum uridine phosphorylase (udp) 0.0078 0.0425 0.5
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0125 0.0777 0.7129
Schistosoma mansoni purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Echinococcus granulosus purine nucleoside phosphorylase 0.0078 0.0425 0.0813
Echinococcus granulosus uridine phosphorylase 1 0.0078 0.0425 0.0813
Onchocerca volvulus 0.0075 0.0403 0.0379

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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