Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Onchocerca volvulus | 0.0041 | 0.1148 | 1 | |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | acetylcholinesterase | 0.0156 | 1 | 1 |
Loa Loa (eye worm) | LGC-31 protein | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0156 | 1 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0041 | 0.1148 | 0.1148 |
Onchocerca volvulus | 0.0041 | 0.1148 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | carboxylesterase | 0.0156 | 1 | 1 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | ACC-1 protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | acetylcholinesterase | 0.0156 | 1 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0156 | 1 | 1 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0156 | 1 | 1 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0041 | 0.1148 | 0.1148 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0026 | 0 | 0.5 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0041 | 0.1148 | 0.1148 |
Onchocerca volvulus | 0.0041 | 0.1148 | 1 | |
Echinococcus granulosus | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0041 | 0.1148 | 0.1148 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0026 | 0 | 0.5 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | ACC-1 protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0041 | 0.1148 | 0.1148 |
Onchocerca volvulus | 0.0041 | 0.1148 | 1 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0041 | 0.1148 | 0.1148 |
Onchocerca volvulus | 0.0041 | 0.1148 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | acetylcholinesterase | 0.0156 | 1 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0041 | 0.1148 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | acetylcholinesterase | 0.0156 | 1 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Cation transporter family protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Carboxylesterase family protein | 0.0156 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Cation transporter family protein | 0.0041 | 0.1148 | 0.1148 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0026 | 0 | 0.5 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0041 | 0.1148 | 0.1148 |
Onchocerca volvulus | 0.0041 | 0.1148 | 1 | |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 1 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0026 | 0 | 0.5 |
Echinococcus multilocularis | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0041 | 0.1148 | 0.1148 |
Schistosoma mansoni | nAChR subunit | 0.0041 | 0.1148 | 0.1148 |
Brugia malayi | Cation transporter family protein | 0.0041 | 0.1148 | 0.1148 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1148 | 0.1148 |
Echinococcus granulosus | carboxylesterase 5A | 0.0156 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.