Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.007 | 0.4455 | 0.4337 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.007 | 0.4455 | 0.4337 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.4198 | 0.4382 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.4455 | 0.5 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.4198 | 0.4075 |
Loa Loa (eye worm) | TAR-binding protein | 0.0065 | 0.3934 | 0.4106 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.4455 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1226 | 0.0969 |
Brugia malayi | TAR-binding protein | 0.0065 | 0.3934 | 0.3975 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3934 | 0.3805 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.777 | 0.8068 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.012 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.4198 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0065 | 0.3934 | 0.3805 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.427 | 0.4333 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0209 | 0.0218 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3934 | 0.3805 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.9581 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.012 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3934 | 0.3805 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0209 | 0.0218 |
Brugia malayi | RNA binding protein | 0.0065 | 0.3934 | 0.3975 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.9581 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.777 | 0.8068 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.9581 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.777 | 0.811 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.777 | 0.811 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.4198 | 0.4075 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.4198 | 0.4075 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.4198 | 0.4075 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0065 | 0.3934 | 0.3975 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.007 | 0.4455 | 0.4337 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0065 | 0.3934 | 0.4106 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0907 | 0.0947 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.4198 | 0.4075 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0907 | 0.0745 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.1226 | 1 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.4198 | 0.4257 |
Brugia malayi | hypothetical protein | 0.007 | 0.4455 | 0.4531 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.4198 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0907 | 0.7399 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.427 | 0.4148 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3934 | 0.3805 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.4455 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.007 | 0.4455 | 0.4337 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.1226 | 0.0969 |
Schistosoma mansoni | tar DNA-binding protein | 0.0065 | 0.3934 | 0.3805 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.427 | 0.4457 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.4198 | 0.4075 |
Loa Loa (eye worm) | RNA binding protein | 0.0065 | 0.3934 | 0.4106 |
Echinococcus granulosus | tar DNA binding protein | 0.0065 | 0.3934 | 0.3805 |
Entamoeba histolytica | hypothetical protein | 0.007 | 0.4455 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.012 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.