Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | adenosine deaminase, putative | 0.0258 | 0.8056 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Treponema pallidum | adenosine deaminase | 0.0258 | 0.8056 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0258 | 0.8056 | 1 |
Brugia malayi | Adenosine/AMP deaminase family protein | 0.0258 | 0.8056 | 1 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0084 | 0 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0258 | 0.8056 | 1 |
Echinococcus granulosus | adenosine deaminase | 0.0258 | 0.8056 | 0.8056 |
Schistosoma mansoni | P2X receptor subunit | 0.03 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0091 | 0.0312 | 0.0388 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0258 | 0.8056 | 0.5 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0258 | 0.8056 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0084 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0258 | 0.8056 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Schistosoma mansoni | P2X receptor subunit | 0.0149 | 0.2997 | 0.2997 |
Mycobacterium ulcerans | adenosine deaminase | 0.0258 | 0.8056 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0258 | 0.8056 | 1 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0258 | 0.8056 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0258 | 0.8056 | 0.8056 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0258 | 0.8056 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0258 | 0.8056 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0149 | 0.2997 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0084 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.4164 | 0.5169 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0258 | 0.8056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0258 | 0.8056 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0091 | 0.0312 | 0.0388 |
Trypanosoma brucei | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0258 | 0.8056 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0258 | 0.8056 | 0.8056 |
Trypanosoma brucei | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.03 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase | 0.0258 | 0.8056 | 0.8056 |
Trypanosoma brucei | AMP deaminase, putative | 0.0084 | 0 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.03 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.