Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0185 | 0.4176 | 0.3437 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0185 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0185 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0123 | 0.1126 | 0.1126 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0127 | 0.1329 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0185 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0305 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0185 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0185 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin l1 | 0.0127 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0123 | 0.1126 | 0.1126 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0185 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0305 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0127 | 0.1329 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0305 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0305 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0185 | 0.4176 | 0.4176 |
Giardia lamblia | Cathepsin B precursor | 0.0123 | 0.1126 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.4176 | 0.3437 |
Echinococcus multilocularis | cathepsin b | 0.0305 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0123 | 0.1126 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0185 | 0.4176 | 0.4176 |
Brugia malayi | cathepsin L-like precursor | 0.0127 | 0.1329 | 0.1329 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Onchocerca volvulus | 0.0185 | 0.4176 | 1 | |
Onchocerca volvulus | 0.0185 | 0.4176 | 1 | |
Toxoplasma gondii | cathepsin CPL | 0.0185 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0127 | 0.1329 | 0.1329 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin b | 0.0305 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0127 | 0.1329 | 0.1329 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0185 | 0.4176 | 1 |
Onchocerca volvulus | 0.0185 | 0.4176 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0123 | 0.1126 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0185 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0127 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.1329 | 0.0228 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0305 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0123 | 0.1126 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Onchocerca volvulus | 0.0185 | 0.4176 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0185 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0127 | 0.1329 | 0.1329 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0123 | 0.1126 | 0.2697 |
Loa Loa (eye worm) | cysteine protease | 0.0185 | 0.4176 | 0.3437 |
Echinococcus multilocularis | cysteine protease | 0.0185 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0185 | 0.4176 | 0.3437 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0185 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0127 | 0.1329 | 0.1329 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.0185 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin b | 0.0305 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0185 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0305 | 1 | 1 |
Onchocerca volvulus | 0.0185 | 0.4176 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0185 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0185 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0127 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.1329 | 0.0228 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0185 | 0.4176 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0185 | 0.4176 | 0.3437 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0185 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.0185 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.1329 | 0.0228 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0185 | 0.4176 | 1 |
Onchocerca volvulus | 0.0185 | 0.4176 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0185 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0185 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0185 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0185 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0305 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.