Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1038 | 0.3959 | 0.3036 |
Onchocerca volvulus | 0.1038 | 0.3959 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0714 | 0.2164 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2127 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1038 | 0.3959 | 0.3959 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1038 | 0.3959 | 0.3959 |
Loa Loa (eye worm) | hypothetical protein | 0.2127 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2127 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0714 | 0.2164 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0714 | 0.2164 | 0.2164 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1038 | 0.3959 | 0.3959 |
Loa Loa (eye worm) | hypothetical protein | 0.0714 | 0.2164 | 0.2164 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1038 | 0.3959 | 1 |
Onchocerca volvulus | 0.1038 | 0.3959 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1038 | 0.3959 | 0.3959 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1038 | 0.3959 | 0.3959 |
Brugia malayi | Cathepsin L-like precursor | 0.1038 | 0.3959 | 0.3959 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1038 | 0.3959 | 0.3036 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0714 | 0.2164 | 0.2164 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1038 | 0.3959 | 0.3959 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1038 | 0.3959 | 0.3036 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Onchocerca volvulus | 0.1038 | 0.3959 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0563 | 0.1326 | 0.1326 |
Echinococcus granulosus | cathepsin b | 0.2127 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2127 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.2127 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2127 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0563 | 0.1326 | 0.1326 |
Plasmodium vivax | unspecified product | 0.0563 | 0.1326 | 0.3349 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0823 | 0.2769 | 0.5478 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0823 | 0.2769 | 0.5478 |
Brugia malayi | Cathepsin L-like precursor | 0.1038 | 0.3959 | 0.3959 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1038 | 0.3959 | 0.3959 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1038 | 0.3959 | 0.3959 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Plasmodium vivax | vivapain-2 | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0714 | 0.2164 | 0.3182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1038 | 0.3959 | 0.3036 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0714 | 0.2164 | 0.2164 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Onchocerca volvulus | 0.1038 | 0.3959 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0714 | 0.2164 | 0.2164 |
Echinococcus granulosus | cathepsin l1 | 0.1038 | 0.3959 | 0.3036 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0823 | 0.2769 | 0.2769 |
Leishmania major | cysteine peptidase A (CPA) | 0.1038 | 0.3959 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1038 | 0.3959 | 0.3036 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0563 | 0.1326 | 0.1326 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1038 | 0.3959 | 0.3959 |
Loa Loa (eye worm) | fibroinase | 0.1038 | 0.3959 | 0.3959 |
Onchocerca volvulus | Cathepsin L homolog | 0.1038 | 0.3959 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0563 | 0.1326 | 0.1326 |
Giardia lamblia | Cathepsin B precursor | 0.0823 | 0.2769 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1038 | 0.3959 | 0.3959 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2127 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0823 | 0.2769 | 0.2769 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1038 | 0.3959 | 0.3959 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Onchocerca volvulus | 0.1038 | 0.3959 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.1038 | 0.3959 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1038 | 0.3959 | 0.3959 |
Entamoeba histolytica | cysteine protease, putative | 0.1038 | 0.3959 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0563 | 0.1326 | 0.1326 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1038 | 0.3959 | 0.3959 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0563 | 0.1326 | 0.1326 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1038 | 0.3959 | 0.3959 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0563 | 0.1326 | 0.1326 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0714 | 0.2164 | 0.2164 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0563 | 0.1326 | 0.1326 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1038 | 0.3959 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0714 | 0.2164 | 0.2164 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1038 | 0.3959 | 1 |
Onchocerca volvulus | 0.1038 | 0.3959 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1038 | 0.3959 | 0.3959 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1038 | 0.3959 | 0.3036 |
Trypanosoma cruzi | cysteine protease, putative | 0.0563 | 0.1326 | 0.1326 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0563 | 0.1326 | 0.1326 |
Echinococcus granulosus | cathepsin l1 | 0.0714 | 0.2164 | 0.0966 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2127 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1038 | 0.3959 | 0.3036 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.1038 | 0.3959 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0714 | 0.2164 | 0.2164 |
Loa Loa (eye worm) | cathepsin B | 0.0823 | 0.2769 | 0.2769 |
Echinococcus multilocularis | cysteine protease | 0.1038 | 0.3959 | 0.3036 |
Plasmodium vivax | vivapain-3 | 0.0563 | 0.1326 | 0.3349 |
Onchocerca volvulus | 0.1038 | 0.3959 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2127 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1038 | 0.3959 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1038 | 0.3959 | 0.3959 |
Plasmodium vivax | vivapain-1 | 0.0563 | 0.1326 | 0.3349 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1038 | 0.3959 | 0.3959 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1038 | 0.3959 | 1 |
Leishmania major | cathepsin L-like protease | 0.1038 | 0.3959 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1038 | 0.3959 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0823 | 0.2769 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1038 | 0.3959 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0714 | 0.2164 | 0.2164 |
Toxoplasma gondii | cathepsin CPL | 0.1038 | 0.3959 | 1 |
Plasmodium vivax | vivapain-2 | 0.1038 | 0.3959 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0823 | 0.2769 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.