Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0511 | 0.4176 | 1 |
Onchocerca volvulus | 0.0511 | 0.4176 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0511 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0841 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.0511 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.035 | 0.1329 | 0.3182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0338 | 0.1126 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0841 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0511 | 0.4176 | 0.3437 |
Echinococcus granulosus | cathepsin l1 | 0.035 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | cysteine protease | 0.0511 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0511 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0511 | 0.4176 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0841 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1329 | 0.0228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.035 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0841 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Onchocerca volvulus | 0.0511 | 0.4176 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0511 | 0.4176 | 0.4176 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0841 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.035 | 0.1329 | 0.3182 |
Plasmodium vivax | vivapain-2 | 0.0511 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0511 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cysteine protease | 0.0511 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0338 | 0.1126 | 0.1126 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1329 | 0.0228 |
Toxoplasma gondii | cathepsin CPL | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.035 | 0.1329 | 0.1329 |
Brugia malayi | Cathepsin L-like precursor | 0.035 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0511 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0511 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0511 | 0.4176 | 0.3437 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.035 | 0.1329 | 0.1329 |
Onchocerca volvulus | 0.0511 | 0.4176 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0511 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0511 | 0.4176 | 0.3437 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | hypothetical protein | 0.0841 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0338 | 0.1126 | 0.2697 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0841 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1126 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0511 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0511 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0511 | 0.4176 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0511 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0511 | 0.4176 | 0.3437 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0511 | 0.4176 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0511 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1329 | 0.0228 |
Loa Loa (eye worm) | fibroinase | 0.0511 | 0.4176 | 0.3437 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Onchocerca volvulus | 0.0511 | 0.4176 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0511 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0511 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.035 | 0.1329 | 0.1329 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.035 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0511 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0511 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.4176 | 0.4176 |
Onchocerca volvulus | Cathepsin L homolog | 0.0511 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0511 | 0.4176 | 0.4176 |
Echinococcus granulosus | cathepsin b | 0.0841 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0511 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0338 | 0.1126 | 0.1126 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0511 | 0.4176 | 0.4176 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0511 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0841 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin b | 0.0841 | 1 | 1 |
Onchocerca volvulus | 0.0511 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0511 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0511 | 0.4176 | 0.4176 |
Giardia lamblia | Cathepsin B precursor | 0.0338 | 0.1126 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.035 | 0.1329 | 0.1329 |
Leishmania major | cathepsin L-like protease | 0.0511 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0511 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cysteine protease | 0.0511 | 0.4176 | 0.4176 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.