Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cpg binding protein | 0.0035 | 0.4619 | 0.8051 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.5609 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.042 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.042 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.5609 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.5609 | 0.5609 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.042 | 0.5 |
Brugia malayi | hypothetical protein | 0.0042 | 0.5609 | 1 |
Brugia malayi | hypothetical protein | 0.0029 | 0.3713 | 0.6041 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.3713 | 0.5 |
Trichomonas vaginalis | helicase, putative | 0.0008 | 0.042 | 0.5 |
Brugia malayi | hypothetical protein | 0.0019 | 0.214 | 0.2757 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.3713 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4619 | 0.4619 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.3713 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.5609 | 0.5609 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0033 | 0.4331 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0839 | 0.0607 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.1265 | 0.1446 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.5609 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4331 | 0.4331 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.1265 | 0.1446 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.1265 | 0.1265 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.042 | 0.5 |
Brugia malayi | CXXC zinc finger family protein | 0.0033 | 0.4331 | 0.7332 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.5609 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.042 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0008 | 0.042 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0035 | 0.4619 | 0.4619 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0839 | 0.0607 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.3713 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.3713 | 0.8229 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.3713 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.8854 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.042 | 0.5 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.5609 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.5609 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.3713 | 0.5 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0531 | 0.0531 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.3713 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0008 | 0.042 | 0.5 |
Onchocerca volvulus | 0.0033 | 0.4331 | 0.5 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0008 | 0.042 | 0.5 |
Echinococcus granulosus | cpg binding protein | 0.0035 | 0.4619 | 0.8051 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.