Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | hexokinase | 0.1983 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0038 | 0.0135 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1983 | 1 | 0.5 |
Echinococcus granulosus | hexokinase type 2 | 0.1983 | 1 | 1 |
Brugia malayi | hexokinase type II | 0.0631 | 0.3138 | 0.3138 |
Trypanosoma brucei | hexokinase | 0.1983 | 1 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0041 | 0.0148 | 0.0148 |
Brugia malayi | Hexokinase family protein | 0.1983 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.1983 | 1 | 1 |
Treponema pallidum | hexokinase (hxk) | 0.1983 | 1 | 0.5 |
Onchocerca volvulus | 0.1983 | 1 | 1 | |
Brugia malayi | Hexokinase family protein | 0.0614 | 0.3052 | 0.3052 |
Echinococcus granulosus | hexokinase | 0.1983 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.1983 | 1 | 1 |
Echinococcus multilocularis | hexokinase type 2 | 0.1983 | 1 | 1 |
Plasmodium falciparum | hexokinase | 0.1983 | 1 | 0.5 |
Toxoplasma gondii | hexokinase | 0.1983 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1983 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.1983 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.1983 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.1244 | 0.6251 | 0.6251 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0045 | 0.0168 | 0.0168 |
Entamoeba histolytica | hexokinase 2 | 0.1983 | 1 | 0.5 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0041 | 0.0148 | 0.0148 |
Loa Loa (eye worm) | hexokinase type II | 0.1983 | 1 | 1 |
Onchocerca volvulus | 0.1983 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0631 | 0.3138 | 0.3138 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0121 | 0.0121 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0038 | 0.0135 | 0.5 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0041 | 0.0148 | 0.0148 |
Echinococcus multilocularis | hexokinase | 0.1983 | 1 | 1 |
Plasmodium vivax | hexokinase, putative | 0.1983 | 1 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0041 | 0.0148 | 0.0148 |
Schistosoma mansoni | hexokinase | 0.1983 | 1 | 1 |
Trypanosoma brucei | hexokinase, putative | 0.1983 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.0614 | 0.3052 | 0.3052 |
Loa Loa (eye worm) | hypothetical protein | 0.0631 | 0.3138 | 0.3138 |
Entamoeba histolytica | hexokinase 1 | 0.1983 | 1 | 0.5 |
Onchocerca volvulus | 0.1983 | 1 | 1 | |
Leishmania major | hexokinase, putative | 0.1983 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0045 | 0.0168 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.1353 | 0.6801 | 0.6801 |
Echinococcus granulosus | hexokinase | 0.1983 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.1983 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.1983 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.1244 | 0.6251 | 0.6251 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.