Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 0.0067 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0112 | 0.0067 | 0.007 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0112 | 0.0067 | 0.0045 |
Echinococcus granulosus | FTZ F1 alpha | 0.0112 | 0.0067 | 0.0124 |
Brugia malayi | ecdysteroid receptor | 0.0112 | 0.0067 | 0.0045 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0112 | 0.0067 | 0.0102 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0112 | 0.0067 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.1502 | 0.9593 | 0.9955 |
Schistosoma mansoni | thyroid hormone receptor | 0.0748 | 0.4425 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0636 | 0.3654 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0748 | 0.4425 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0636 | 0.3654 | 0.8249 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0112 | 0.0067 | 0.0102 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0112 | 0.0067 | 0.0102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0112 | 0.0067 | 0.007 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0112 | 0.0067 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.1509 | 0.9636 | 0.9636 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0112 | 0.0067 | 0.0102 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 0.0067 | 0.0124 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0112 | 0.0067 | 0.007 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0112 | 0.0067 | 0.0124 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0112 | 0.0067 | 0.007 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0112 | 0.0067 | 0.0124 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0112 | 0.0067 | 0.0045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0112 | 0.0067 | 0.0045 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 0.0067 | 0.0045 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0636 | 0.3654 | 0.8249 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.1509 | 0.9636 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0112 | 0.0067 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0112 | 0.0067 | 0.0124 |
Onchocerca volvulus | 0.0112 | 0.0067 | 0.5 | |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0112 | 0.0067 | 0.0124 |
Schistosoma mansoni | nuclear hormone receptor | 0.0112 | 0.0067 | 0.0102 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0112 | 0.0067 | 0.0102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0112 | 0.0067 | 0.007 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.1509 | 0.9636 | 0.9636 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0112 | 0.0067 | 0.0124 |
Brugia malayi | steroid hormone receptor | 0.0112 | 0.0067 | 0.0045 |
Brugia malayi | nuclear hormone receptor | 0.0112 | 0.0067 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0112 | 0.0067 | 0.007 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0112 | 0.0067 | 0.0045 |
Brugia malayi | nuclear receptor NHR-88 | 0.0112 | 0.0067 | 0.0045 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0112 | 0.0067 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0748 | 0.4425 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0112 | 0.0067 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 0.0067 | 0.0045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0112 | 0.0067 | 0.0102 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0112 | 0.0067 | 0.0102 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0112 | 0.0067 | 0.007 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0112 | 0.0067 | 0.0102 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0112 | 0.0067 | 0.0124 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0112 | 0.0067 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0112 | 0.0067 | 0.0045 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0112 | 0.0067 | 0.0124 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0112 | 0.0067 | 0.007 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0112 | 0.0067 | 0.0045 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0112 | 0.0067 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0112 | 0.0067 | 0.0045 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0112 | 0.0067 | 0.0102 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0112 | 0.0067 | 0.0045 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0112 | 0.0067 | 0.0045 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0112 | 0.0067 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.0067 | 0.007 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.