Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hexokinase | 0.2413 | 1 | 1 |
Echinococcus multilocularis | hexokinase | 0.2413 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.2413 | 1 | 1 |
Onchocerca volvulus | 0.2413 | 1 | 1 | |
Brugia malayi | Hexokinase family protein | 0.1514 | 0.6254 | 0.6254 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0043 | 0.0127 | 0.0127 |
Echinococcus multilocularis | hexokinase type 2 | 0.2413 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.004 | 0.0115 | 0.5 |
Brugia malayi | hexokinase type II | 0.0767 | 0.3144 | 0.3144 |
Loa Loa (eye worm) | hexokinase | 0.2413 | 1 | 1 |
Toxoplasma gondii | hexokinase | 0.2413 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.2413 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.2413 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0747 | 0.3058 | 0.3058 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0043 | 0.0127 | 0.0127 |
Entamoeba histolytica | hexokinase 2 | 0.2413 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.2413 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.004 | 0.0115 | 0.5 |
Entamoeba histolytica | hexokinase 1 | 0.2413 | 1 | 0.5 |
Trypanosoma brucei | hexokinase, putative | 0.2413 | 1 | 0.5 |
Loa Loa (eye worm) | hexokinase | 0.2413 | 1 | 1 |
Treponema pallidum | hexokinase (hxk) | 0.2413 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0047 | 0.0143 | 0.0143 |
Loa Loa (eye worm) | hexokinase type II | 0.2413 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1646 | 0.6804 | 0.6804 |
Loa Loa (eye worm) | hexokinase | 0.1514 | 0.6254 | 0.6254 |
Echinococcus multilocularis | hexokinase | 0.2413 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0767 | 0.3144 | 0.3144 |
Trypanosoma cruzi | hexokinase, putative | 0.2413 | 1 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0043 | 0.0127 | 0.0127 |
Leishmania major | hexokinase, putative | 0.2413 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.2413 | 1 | 0.5 |
Echinococcus granulosus | hexokinase type 2 | 0.2413 | 1 | 1 |
Plasmodium vivax | hexokinase, putative | 0.2413 | 1 | 0.5 |
Plasmodium falciparum | hexokinase | 0.2413 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.2413 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0767 | 0.3144 | 0.3144 |
Leishmania major | hexokinase, putative | 0.2413 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0103 | 0.0103 |
Trypanosoma brucei | hexokinase | 0.2413 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0047 | 0.0143 | 0.0143 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0043 | 0.0127 | 0.0127 |
Schistosoma mansoni | hexokinase | 0.2413 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0747 | 0.3058 | 0.3058 |
Onchocerca volvulus | 0.2413 | 1 | 1 | |
Onchocerca volvulus | 0.2413 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.