Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | coup transcription factor | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Echinococcus granulosus | nicalin | 0.0168 | 0.0427 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.0352 | 0.0352 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Brugia malayi | nuclear receptor NHR-67 | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.035 | 0.1271 | 0.12 |
Schistosoma mansoni | subfamily A22A unassigned peptidase (A22 family) | 0.0937 | 0.399 | 0.3942 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0313 | 0.1097 | 0.1097 |
Brugia malayi | hypothetical protein | 0.035 | 0.1271 | 0.12 |
Schistosoma mansoni | thyroid hormone receptor | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | ecdysteroid receptor | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0313 | 0.1097 | 0.1097 |
Brugia malayi | hypothetical protein | 0.035 | 0.1271 | 0.12 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0663 | 0.2719 | 0.266 |
Onchocerca volvulus | 0.0663 | 0.2719 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Schistosoma mansoni | hypothetical protein | 0.0457 | 0.1765 | 0.1699 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0663 | 0.2719 | 0.2719 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | gamma-secretase subunit pen-2 | 0.0879 | 0.3724 | 0.3673 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0663 | 0.2719 | 0.2719 |
Echinococcus multilocularis | presenilin enhancer 2 | 0.0879 | 0.3724 | 0.3673 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0313 | 0.1097 | 0.1025 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0663 | 0.2719 | 0.266 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | hypothetical protein | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0663 | 0.2719 | 0.266 |
Schistosoma mansoni | alzheimer's disease beta-amyloid related | 0.0131 | 0.0254 | 0.0175 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0313 | 0.1097 | 0.1025 |
Schistosoma mansoni | gamma-secretase subunit aph-1 | 0.2234 | 1 | 1 |
Brugia malayi | tailless protein | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1271 | 0.1271 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.035 | 0.1271 | 0.12 |
Brugia malayi | hypothetical protein | 0.0457 | 0.1765 | 0.1699 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1271 | 0.1271 |
Brugia malayi | nuclear receptor NHR-88 | 0.0663 | 0.2719 | 0.266 |
Echinococcus multilocularis | Nicastrin | 0.0457 | 0.1765 | 0.1699 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0313 | 0.1097 | 0.1097 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1271 | 0.1271 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.035 | 0.1271 | 0.12 |
Brugia malayi | nuclear hormone receptor | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0663 | 0.2719 | 0.2719 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.0597 | 0.0521 |
Echinococcus multilocularis | Nicastrin | 0.0457 | 0.1765 | 0.1699 |
Echinococcus multilocularis | geminin | 0.0205 | 0.0597 | 0.0521 |
Loa Loa (eye worm) | gamma-secretase subunit aph-1 | 0.2234 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0663 | 0.2719 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.035 | 0.1271 | 0.1271 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Brugia malayi | nuclear hormone receptor | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.0597 | 0.0521 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Loa Loa (eye worm) | DR-78 | 0.0313 | 0.1097 | 0.1097 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0663 | 0.2719 | 0.2719 |
Brugia malayi | Amyloid A4 extracellular domain containing protein | 0.0358 | 0.1308 | 0.1238 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Brugia malayi | hypothetical protein | 0.0457 | 0.1765 | 0.1699 |
Brugia malayi | Presenilin spe-4 | 0.0328 | 0.117 | 0.1098 |
Echinococcus granulosus | Nicastrin | 0.0457 | 0.1765 | 0.1699 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0663 | 0.2719 | 0.266 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0313 | 0.1097 | 0.1025 |
Schistosoma mansoni | nuclear receptor | 0.0313 | 0.1097 | 0.1025 |
Toxoplasma gondii | hypothetical protein | 0.0328 | 0.117 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0663 | 0.2719 | 0.266 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | nuclear receptor NHR-88 | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0663 | 0.2719 | 0.2719 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.008 | 0.008 |
Trichomonas vaginalis | Clan AD, family A22, presenilin-like aspartic peptidase | 0.0937 | 0.399 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0663 | 0.2719 | 0.266 |
Schistosoma mansoni | nuclear receptor | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | ecdysone receptor | 0.0313 | 0.1097 | 0.1025 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0663 | 0.2719 | 0.266 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0313 | 0.1097 | 0.1025 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.0871 | 0.3683 | 0.9136 |
Schistosoma mansoni | zinc finger protein | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | hypothetical protein | 0.0328 | 0.117 | 0.1098 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | Presenilin spe-4 | 0.0328 | 0.117 | 0.1098 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0278 | 0.0936 | 0.5 |
Echinococcus granulosus | presenilin enhancer 2 | 0.0879 | 0.3724 | 0.3673 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1271 | 0.1271 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | nuclear receptor RXR | 0.035 | 0.1271 | 0.12 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0663 | 0.2719 | 0.266 |
Echinococcus multilocularis | gamma secretase subunit aph 1 | 0.2234 | 1 | 1 |
Trichomonas vaginalis | Clan AD, family A22, presenilin-like aspartic peptidase | 0.0937 | 0.399 | 1 |
Echinococcus granulosus | presenilin | 0.0937 | 0.399 | 0.3942 |
Echinococcus multilocularis | presenilin | 0.0937 | 0.399 | 0.3942 |
Schistosoma mansoni | nuclear hormone receptor | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | conserved hypotetical protein | 0.0313 | 0.1097 | 0.1025 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0663 | 0.2719 | 0.266 |
Leishmania major | presenilin-like aspartic peptidase, putative,presenilin-like aspartic peptidase, clan AD, family A22A, putative | 0.0937 | 0.399 | 1 |
Echinococcus granulosus | geminin | 0.0205 | 0.0597 | 0.0521 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0457 | 0.1765 | 0.1765 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | steroid hormone receptor | 0.0663 | 0.2719 | 0.266 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0313 | 0.1097 | 0.1025 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0663 | 0.2719 | 0.2719 |
Loa Loa (eye worm) | hypothetical protein | 0.035 | 0.1271 | 0.1271 |
Trypanosoma cruzi | Aph-1 protein, putative | 0.0871 | 0.3683 | 0.9136 |
Brugia malayi | hypothetical protein | 0.0328 | 0.117 | 0.1098 |
Trypanosoma brucei | Aph-1 protein, putative | 0.0871 | 0.3683 | 0.9136 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Presenilin-like protein At2g29900 | 0.0328 | 0.117 | 0.1098 |
Schistosoma mansoni | thyroid hormone receptor | 0.0663 | 0.2719 | 0.266 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Brugia malayi | hypothetical protein | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.035 | 0.1271 | 0.12 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0313 | 0.1097 | 0.1025 |
Echinococcus multilocularis | nicalin | 0.0168 | 0.0427 | 0.0349 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | presenilin spe-4 | 0.0328 | 0.117 | 0.117 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0663 | 0.2719 | 0.266 |
Echinococcus granulosus | FTZ F1 alpha | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Presenilin family protein | 0.0937 | 0.399 | 0.3942 |
Schistosoma mansoni | nuclear hormone receptor | 0.0313 | 0.1097 | 0.1025 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0663 | 0.2719 | 0.266 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0663 | 0.2719 | 0.266 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0663 | 0.2719 | 1 |
Trichomonas vaginalis | Clan AD, family A22, presenilin-like aspartic peptidase | 0.0937 | 0.399 | 1 |
Trypanosoma brucei | presenilin-like aspartic peptidase, putative | 0.0937 | 0.399 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.035 | 0.1271 | 0.12 |
Brugia malayi | Presenilin spe-4 | 0.0328 | 0.117 | 0.1098 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0663 | 0.2719 | 0.2719 |
Brugia malayi | hypothetical protein | 0.0328 | 0.117 | 0.1098 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0313 | 0.1097 | 0.1025 |
Trypanosoma cruzi | presenilin-like aspartic peptidase, putative | 0.0937 | 0.399 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0663 | 0.2719 | 0.266 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Entamoeba histolytica | presenilin 1 peptidase, putative | 0.0937 | 0.399 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0313 | 0.1097 | 0.1025 |
Echinococcus granulosus | gamma secretase subunit aph 1 | 0.2234 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0663 | 0.2719 | 0.266 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0663 | 0.2719 | 0.266 |
Trypanosoma brucei | Presenilin enhancer-2 subunit of gamma secretase, putative | 0.0265 | 0.0875 | 0.1259 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0663 | 0.2719 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | hypothetical protein | 0.0663 | 0.2719 | 0.2719 |
Loa Loa (eye worm) | gamma-secretase subunit pen-2 | 0.0879 | 0.3724 | 0.3724 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.035 | 0.1271 | 0.12 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.0956 | 0.0956 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0663 | 0.2719 | 0.266 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0663 | 0.2719 | 0.2719 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | nuclear receptor RXR | 0.0313 | 0.1097 | 0.1025 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0313 | 0.1097 | 0.1025 |
Trypanosoma cruzi | presenilin-like aspartic peptidase, putative | 0.0937 | 0.399 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0663 | 0.2719 | 0.266 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0313 | 0.1097 | 0.1025 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0663 | 0.2719 | 0.266 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0313 | 0.1097 | 0.1025 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0313 | 0.1097 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Schistosoma mansoni | nuclear hormone receptor | 0.0663 | 0.2719 | 0.266 |
Loa Loa (eye worm) | calcium channel | 0.0093 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.1097 | 0.1097 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0663 | 0.2719 | 0.266 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.