Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0221 | 0.9749 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0029 | 0.0851 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0029 | 0.0851 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0029 | 0.0851 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0029 | 0.0851 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Brugia malayi | nuclear hormone receptor | 0.0221 | 0.9749 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.9524 | 0.977 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0029 | 0.0851 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0029 | 0.0851 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0029 | 0.0851 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0029 | 0.0851 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0029 | 0.0851 | 0.5 |
Trypanosoma brucei | trans-sialidase | 0.0029 | 0.0851 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.