Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cysteine peptidase, putative | 0.0204 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0333 | 0.9842 | 0.9842 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0204 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0204 | 0.4176 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Trypanosoma brucei | DNA topoisomerase IB, large subunit | 0.0249 | 0.6154 | 1 |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0135 | 0.1126 | 0.2697 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.1329 | 0.1329 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0204 | 0.4176 | 0.4243 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0204 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cathepsin b | 0.0337 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0337 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0337 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0337 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0135 | 0.1126 | 0.183 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.4176 | 0.3437 |
Echinococcus granulosus | cathepsin l1 | 0.0204 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0204 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0204 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Schistosoma mansoni | DNA topoisomerase type I | 0.0249 | 0.6154 | 0.6154 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1329 | 0.0228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Leishmania major | DNA topoisomerase IB, large subunit | 0.0249 | 0.6154 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.014 | 0.1329 | 0.1329 |
Plasmodium vivax | topoisomerase I, putative | 0.0333 | 0.9842 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.014 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.1329 | 0.3182 |
Echinococcus granulosus | DNA topoisomerase 1 | 0.0333 | 0.9842 | 0.9842 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0204 | 0.4176 | 0.3437 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1329 | 0.0228 |
Echinococcus multilocularis | DNA topoisomerase 1 | 0.0333 | 0.9842 | 0.9842 |
Brugia malayi | Cathepsin L-like precursor | 0.0204 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Entamoeba histolytica | cysteine protease, putative | 0.0204 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0337 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0204 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.014 | 0.1329 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0337 | 1 | 1 |
Onchocerca volvulus | 0.0204 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Onchocerca volvulus | 0.0204 | 0.4176 | 1 | |
Loa Loa (eye worm) | DNA topoisomerase I | 0.0333 | 0.9842 | 0.9821 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1126 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Onchocerca volvulus | 0.0204 | 0.4176 | 1 | |
Onchocerca volvulus | 0.0204 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0204 | 0.4176 | 0.3437 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0204 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0204 | 0.4176 | 0.4176 |
Trypanosoma cruzi | DNA topoisomerase IB, large subunit, putative | 0.0249 | 0.6154 | 0.6154 |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0204 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0204 | 0.4176 | 0.4176 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0204 | 0.4176 | 0.4176 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0204 | 0.4176 | 0.4243 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0204 | 0.4176 | 0.4176 |
Onchocerca volvulus | Cathepsin L homolog | 0.0204 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0204 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin b | 0.0337 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0204 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.1329 | 0.0228 |
Plasmodium vivax | vivapain-2 | 0.0204 | 0.4176 | 0.4243 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0204 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0204 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Toxoplasma gondii | cathepsin CPL | 0.0204 | 0.4176 | 0.3499 |
Loa Loa (eye worm) | fibroinase | 0.0204 | 0.4176 | 0.3437 |
Plasmodium falciparum | topoisomerase I | 0.0333 | 0.9842 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0204 | 0.4176 | 0.3437 |
Brugia malayi | DNA topoisomerase I | 0.0333 | 0.9842 | 0.9842 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0204 | 0.4176 | 0.4176 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.014 | 0.1329 | 0.1329 |
Leishmania major | cysteine peptidase A (CPA) | 0.0204 | 0.4176 | 0.6066 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0204 | 0.4176 | 0.4176 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0337 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0135 | 0.1126 | 0.1126 |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0204 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.0204 | 0.4176 | 0.6066 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0204 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0204 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0204 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | cysteine protease | 0.0204 | 0.4176 | 0.3437 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0204 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0337 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Plasmodium vivax | vivapain-2 | 0.0204 | 0.4176 | 0.4243 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.014 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0204 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Onchocerca volvulus | 0.0204 | 0.4176 | 1 | |
Schistosoma mansoni | DNA topoisomerase type I | 0.0249 | 0.6154 | 0.6154 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.014 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0204 | 0.4176 | 0.6786 |
Echinococcus granulosus | cathepsin l1 | 0.014 | 0.1329 | 0.1329 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0204 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.0204 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0135 | 0.1126 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0204 | 0.4176 | 0.4243 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0135 | 0.1126 | 0.1126 |
Brugia malayi | Cathepsin L-like precursor | 0.014 | 0.1329 | 0.1329 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0204 | 0.4176 | 1 |
Toxoplasma gondii | DNA topoisomerase I, putative | 0.0333 | 0.9842 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.