Detailed information for compound 899641

Basic information

Technical information
  • TDR Targets ID: 899641
  • Name: 2-methylpropyl 6-[3-methoxy-4-(3-methylbutoxy )phenyl]-8-methyl-4-oxo-3,6-dihydro-2H-pyrimi do[2,1-b][1,3]thiazine-7-carboxylate
  • MW: 474.613 | Formula: C25H34N2O5S
  • H donors: 0 H acceptors: 2 LogP: 4.84 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1OCCC(C)C)C1N2C(=O)CCSC2=NC(=C1C(=O)OCC(C)C)C
  • InChi: 1S/C25H34N2O5S/c1-15(2)9-11-31-19-8-7-18(13-20(19)30-6)23-22(24(29)32-14-16(3)4)17(5)26-25-27(23)21(28)10-12-33-25/h7-8,13,15-16,23H,9-12,14H2,1-6H3
  • InChiKey: VRBAFADKUBMASX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • isobutyl 6-(4-isopentyloxy-3-methoxy-phenyl)-8-methyl-4-oxo-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate
  • 6-(4-isopentyloxy-3-methoxyphenyl)-8-methyl-4-oxo-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid isobutyl ester
  • 6-(4-isoamoxy-3-methoxy-phenyl)-4-keto-8-methyl-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid isobutyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni tar DNA-binding protein 0.0087 0.0136 0.0135
Echinococcus multilocularis mitogen activated protein kinase 3 0.0054 0.007 0.0064
Echinococcus multilocularis snurportin 1 0.024 0.0437 0.0431
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.0048 0.0046
Echinococcus granulosus mitogen activated protein kinase 0.0054 0.007 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0626 0.1197 0.2096
Echinococcus granulosus lysosomal alpha glucosidase 0.0378 0.0708 0.0706
Echinococcus multilocularis sterol regulatory element binding protein 0.0033 0.0029 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0027 0.0017 0.0016
Leishmania major 4-coumarate:coa ligase-like protein 0.0058 0.0079 0.0138
Onchocerca volvulus 0.0036 0.0036 0.0298
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.0011 0.001
Schistosoma mansoni nuclear receptor 0.0043 0.0048 0.0047
Onchocerca volvulus 0.0029 0.0021 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0098 0.0157 0.0887
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0249 0.0437
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0007 0.0012
Schistosoma mansoni thyroid hormone receptor 0.0091 0.0143 0.0142
Schistosoma mansoni coup transcription factor 0.0091 0.0143 0.0142
Brugia malayi hypothetical protein 0.0085 0.0132 0.0746
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0091 0.0143 0.0137
Echinococcus multilocularis cysteine protease 0.0029 0.0021 0.0015
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.2916 0.5711 1
Brugia malayi Probable ATP-dependent helicase DHX35 0.0035 0.0032 0.0171
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0049 0.0086
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0022 0.0007 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0193
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0036 0.0714
Toxoplasma gondii HEAT repeat-containing protein 0.0022 0.0008 0.0071
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0022 0.0007 0.0001
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.2916 0.5711 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0049 0.0078
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0029 0.0021 0.0015
Echinococcus granulosus cathepsin l1 0.0029 0.0021 0.0019
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0091 0.0143 0.0142
Schistosoma mansoni nuclear receptor nhr-48 0.0043 0.0048 0.0047
Schistosoma mansoni cpg binding protein 0.0168 0.0294 0.0293
Loa Loa (eye worm) calpain family protein 1 0.0053 0.0068 0.0376
Toxoplasma gondii aldehyde dehydrogenase 0.0035 0.0033 0.0522
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1557 0.3033 0.3028
Brugia malayi CHE-14 protein 0.0033 0.0029 0.0153
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.007 0.0123
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0029 0.0021 0.0015
Brugia malayi Cathepsin L-like precursor 0.0029 0.0021 0.0108
Mycobacterium ulcerans acyl-CoA synthetase 0.0058 0.0079 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0004
Echinococcus multilocularis nuclear receptor nhr 48 0.0043 0.0048 0.0042
Echinococcus granulosus survival motor neuron protein 1 0.0347 0.0648 0.0646
Loa Loa (eye worm) hypothetical protein 0.0058 0.0079 0.0438
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0306 0.0567 0.0985
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0017 0.0016
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0041 0.0045 0.0932
Echinococcus granulosus neutral alpha glucosidase AB 0.0084 0.0129 0.0127
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0022 0.0007 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0905 0.1747 0.306
Echinococcus multilocularis neuropeptide s receptor 0.026 0.0477 0.0471
Schistosoma mansoni RAR-like nuclear receptor 0.0091 0.0143 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0594 0.1134 0.1986
Entamoeba histolytica acyl-CoA synthetase, putative 0.0058 0.0079 0.0138
Loa Loa (eye worm) intermediate filament protein 0.01 0.0161 0.0908
Trichomonas vaginalis conserved hypothetical protein 0.2916 0.5711 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0043 0.0048 0.0265
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0036 0.0055
Trichomonas vaginalis sucrase-isomaltase, putative 0.0084 0.0129 0.0226
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0026 0.0045
Entamoeba histolytica cysteine protease, putative 0.0029 0.0021 0.0037
Entamoeba histolytica DNA repair and recombination protein, putative 0.2916 0.5711 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0035 0.0061
Trichomonas vaginalis glucosylceramidase, putative 0.0905 0.1747 0.306
Echinococcus granulosus snurportin 1 0.024 0.0437 0.0435
Loa Loa (eye worm) hypothetical protein 0.0071 0.0104 0.0582
Onchocerca volvulus 0.0043 0.0048 0.0408
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0058 0.0079 0.1524
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Echinococcus multilocularis geminin 0.057 0.1087 0.1081
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0006 0.0022
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Onchocerca volvulus 0.0058 0.0079 0.0675
Echinococcus granulosus histone lysine methyltransferase setb 0.0027 0.0017 0.0015
Toxoplasma gondii ABC1 family protein 0.0036 0.0036 0.0569
Echinococcus multilocularis calpain family protein 1, d 0.0037 0.0037 0.0031
Echinococcus granulosus cpg binding protein 0.0168 0.0294 0.0292
Brugia malayi Nuclear hormone receptor-like 1 0.0091 0.0143 0.0805
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0006 0.0415
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0091 0.0143 0.0137
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Entamoeba histolytica hypothetical protein, conserved 0.2916 0.5711 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0048 0.0059 0.0053
Mycobacterium ulcerans aldehyde dehydrogenase 0.0035 0.0033 0.0572
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.0048 0.0042
Onchocerca volvulus 0.01 0.0161 0.14
Brugia malayi conserved hypotetical protein 0.0043 0.0048 0.0265
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0075 0.0112 0.063
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0036 0.0626
Plasmodium vivax importin-beta 2, putative 0.0022 0.0008 0.0321
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.007 0.0069
Onchocerca volvulus 0.0036 0.0036 0.0298
Loa Loa (eye worm) ctsf protein 0.0029 0.0021 0.0108
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0049 0.0086
Brugia malayi nuclear receptor NHR-88 0.0043 0.0048 0.0265
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.2916 0.5711 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0087 0.0135 0.0236
Onchocerca volvulus 0.0029 0.0021 0.0166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0035 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.0035 0.0032 0.0171
Schistosoma mansoni glutaminase 0.0263 0.0482 0.0481
Brugia malayi Cytochrome P450 family protein 0.0052 0.0066 0.0365
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0058 0.0079 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0058 0.0079 0.4735
Echinococcus multilocularis neutral alpha glucosidase AB 0.0084 0.0129 0.0123
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0091 0.0143 0.0805
Leishmania major glycosyl hydrolase-like protein 0.0031 0.0026 0.0045
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0035 0.0033 0.0027
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0199
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0112 0.0189
Brugia malayi Cathepsin L-like precursor 0.0029 0.0021 0.0108
Plasmodium falciparum importin beta, putative 0.0022 0.0008 0.0592
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0091 0.0143 0.0805
Echinococcus granulosus dnaJ subfamily B 0.2258 0.4413 0.4412
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Schistosoma mansoni lozenge 0.0045 0.0054 0.0053
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0043 0.0048 0.0046
Brugia malayi Importin beta-1 subunit 0.0022 0.0008 0.0035
Brugia malayi hypothetical protein 0.0043 0.0048 0.0265
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.0048 0.0408
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0004 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Trichomonas vaginalis glutaminase, putative 0.0263 0.0482 0.0843
Trichomonas vaginalis glucosylceramidase, putative 0.0905 0.1747 0.306
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0129 0.0226
Schistosoma mansoni hypothetical protein 0.0071 0.0104 0.0103
Trichomonas vaginalis glucosylceramidase, putative 0.0626 0.1197 0.2096
Entamoeba histolytica hypothetical protein 0.0085 0.0132 0.0232
Brugia malayi RNA, U transporter 1 0.0064 0.009 0.0503
Onchocerca volvulus 0.0029 0.0021 0.0166
Schistosoma mansoni hypothetical protein 0.009 0.0142 0.0141
Brugia malayi intermediate filament protein 0.01 0.0161 0.0908
Trypanosoma cruzi PAB1-binding protein , putative 0.002 0.0004 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Toxoplasma gondii histone lysine methyltransferase SET1 0.0301 0.0558 1
Echinococcus granulosus nuclear receptor nhr 48 0.0043 0.0048 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0091 0.0143 0.0805
Mycobacterium tuberculosis Conserved hypothetical protein 0.0161 0.0282 0.6605
Brugia malayi nuclear hormone receptor family member odr-7 0.0043 0.0048 0.0265
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0036 0.0035
Trichomonas vaginalis helicase, putative 0.0036 0.0035 0.0061
Trichomonas vaginalis set domain proteins, putative 0.0188 0.0335 0.0586
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0043 0.0048 0.0042
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0075 0.0112 0.0106
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0033 0.0029 0.0153
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0071 0.0104 0.058
Echinococcus granulosus cathepsin L cysteine proteinase 0.0029 0.0021 0.0019
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0055 0.0073 0.0071
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0073 0.0072
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0091 0.0143 0.0805
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0026 0.0045
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0054 0.007 0.0123
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.2916 0.5711 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0036 0.0063
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0091 0.0143 0.0137
Echinococcus granulosus sterol regulatory element binding protein 0.0033 0.0029 0.0027
Onchocerca volvulus 0.0188 0.0335 0.2936
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0007 0.0001
Mycobacterium ulcerans leucyl aminopeptidase 0.0082 0.0126 0.2523
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0022 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0007 0.0004
Brugia malayi hypothetical protein 0.0347 0.0648 0.3698
Echinococcus granulosus cathepsin l cysteine peptidase 0.0029 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0033 0.0029 0.0153
Loa Loa (eye worm) MH2 domain-containing protein 0.0261 0.0479 0.2733
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0029 0.0021 0.0037
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.2916 0.5711 1
Brugia malayi calpain family protein 1 0.0053 0.0068 0.0376
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0031 0.0025 0.0019
Echinococcus multilocularis protein patched 0.0033 0.0029 0.0023
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0285 0.0526 0.3001
Echinococcus granulosus geminin 0.057 0.1087 0.1085
Trypanosoma brucei glucosidase, putative 0.0084 0.0129 0.0219
Trichomonas vaginalis glucosylceramidase, putative 0.0905 0.1747 0.306
Onchocerca volvulus Cathepsin L homolog 0.0029 0.0021 0.0166
Echinococcus granulosus FTZ F1 alpha 0.0091 0.0143 0.0141
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0026 0.0045
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0036 0.0063
Schistosoma mansoni lipoxygenase 0.0031 0.0025 0.0024
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0145 0.0249 0.0429
Onchocerca volvulus 0.0027 0.0017 0.0128
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0036 0.0714
Mycobacterium tuberculosis Conserved protein 0.0036 0.0036 0.0714
Entamoeba histolytica hypothetical protein 0.0019 0.0001 0.0002
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.007 0.0123
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.009 0.0142 0.014
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0004 0.028
Onchocerca volvulus 0.0071 0.0104 0.0895
Plasmodium vivax acyl-CoA synthetase, putative 0.0043 0.005 0.3717
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0091 0.0143 0.0805
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0129 0.0226
Plasmodium vivax vivapain-2 0.0029 0.0021 0.1365
Onchocerca volvulus 0.0253 0.0462 0.4063
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0022 0.0007 0.0005
Brugia malayi Cathepsin L-like precursor 0.0029 0.0021 0.0108
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0043 0.0048 0.0408
Echinococcus multilocularis thyroid hormone receptor alpha 0.0091 0.0143 0.0137
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0031 0.0025 0.0023
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0043 0.0048 0.0047
Echinococcus multilocularis expressed conserved protein 0.0072 0.0106 0.01
Loa Loa (eye worm) hypothetical protein 0.0058 0.0079 0.0438
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Schistosoma mansoni hypothetical protein 0.009 0.0142 0.0141
Schistosoma mansoni retinoic acid receptor RXR 0.0091 0.0143 0.0142
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.0567 0.0992
Brugia malayi nuclear receptor RXR 0.0043 0.0048 0.0265
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0048 0.0058 0.0058
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0193
Leishmania major hypothetical protein, conserved 0.0036 0.0036 0.0063
Loa Loa (eye worm) isocitrate dehydrogenase 0.0022 0.0007 0.0027
Schistosoma mansoni hypothetical protein 0.0085 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0272
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0091 0.0143 0.0142
Loa Loa (eye worm) nuclear hormone receptor 0.0043 0.0048 0.0265
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0035 0.0033 0.0652
Schistosoma mansoni microtubule-associated protein tau 0.5093 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0002 0.0004
Brugia malayi orphan nuclear receptor NR2E1 0.0043 0.0048 0.0265
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0084 0.0129 0.0728
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0048 0.0058 0.0058
Echinococcus multilocularis musashi 0.01 0.0161 0.0155
Leishmania major 4-coumarate:coa ligase-like protein 0.0058 0.0079 0.0138
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0036 0.0063
Echinococcus granulosus tar DNA binding protein 0.0087 0.0136 0.0134
Schistosoma mansoni hypothetical protein 0.0032 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0362 0.0678 0.3871
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0091 0.0143 0.0805
Brugia malayi hypothetical protein 0.0048 0.0058 0.0322
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0129 0.0226
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0043 0.0041
Plasmodium falciparum acyl-CoA synthetase 0.0043 0.005 0.3893
Echinococcus multilocularis leucine aminopeptidase protein 0.0082 0.0126 0.012
Schistosoma mansoni tar DNA-binding protein 0.0087 0.0136 0.0135
Brugia malayi nuclear hormone receptor 0.0091 0.0143 0.0805
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0026 0.0045
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0031 0.0026 0.0207
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0027 0.0017 0.0011
Loa Loa (eye worm) DEAH box polypeptide 35 0.0035 0.0032 0.0171
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0017 0.0016
Onchocerca volvulus 0.0159 0.0277 0.2423
Mycobacterium ulcerans aldehyde dehydrogenase 0.0035 0.0033 0.0572
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0129 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.0181 0.0317
Loa Loa (eye worm) calpain family protein 1 0.0037 0.0037 0.0199
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0029 0.0021 0.1607
Brugia malayi Cathepsin L-like precursor 0.0029 0.0021 0.0108
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0058 0.0079 0.1524
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0075 0.0112 0.0196
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0036 0.0063
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0006 0.0004
Echinococcus multilocularis transcription factor Dp 1 0.0043 0.005 0.0044
Plasmodium falciparum M17 leucyl aminopeptidase 0.0082 0.0126 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0007 0.0001
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0055 0.0073 0.0067
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0043 0.0048 0.0042
Echinococcus granulosus transcription factor Dp 1 0.0043 0.005 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0058 0.0079 0.0438
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0002 0.0004
Trichomonas vaginalis glucosylceramidase, putative 0.0594 0.1134 0.1986
Trypanosoma brucei importin beta-1 subunit, putative 0.0022 0.0008 0.0007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0043 0.0041
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0022 0.0007 0.0205
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0041 0.0045 0.0932
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0193
Brugia malayi Glycosyl hydrolases family 31 protein 0.0031 0.0026 0.0134
Loa Loa (eye worm) glutaminase 0.0263 0.0482 0.2747
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Loa Loa (eye worm) hypothetical protein 0.0046 0.0055 0.0304
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0036 0.0193
Mycobacterium ulcerans beta-lactamase 0.0036 0.0036 0.0626
Trypanosoma brucei protein kinase, putative 0.0054 0.007 0.0115
Trypanosoma brucei glycosyl hydrolase-like protein 0.0031 0.0026 0.0037
Echinococcus multilocularis calpain A 0.0055 0.0073 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0058 0.0079 0.1738
Schistosoma mansoni transcription factor LCR-F1 0.0085 0.0132 0.0131
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0091 0.0143 0.0137
Trichomonas vaginalis glucosylceramidase, putative 0.0594 0.1134 0.1986
Plasmodium falciparum ataxin-2 like protein, putative 0.002 0.0004 0.028
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0043 0.0048 0.0042
Toxoplasma gondii isocitrate dehydrogenase 0.0022 0.0007 0.0045
Schistosoma mansoni thyroid hormone receptor 0.0091 0.0143 0.0142
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.0324 0.0318
Schistosoma mansoni zinc finger protein 0.0043 0.0048 0.0047
Onchocerca volvulus Cathepsin L homolog 0.0029 0.0021 0.0166
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0091 0.0143 0.0137
Onchocerca volvulus Cathepsin F homolog 0.0029 0.0021 0.0166
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0091 0.0143 0.0141
Echinococcus multilocularis Niemann Pick C1 protein 0.0077 0.0115 0.0109
Schistosoma mansoni steroid hormone receptor ad4bp 0.0091 0.0143 0.0142
Echinococcus multilocularis cathepsin L cysteine protease 0.0029 0.0021 0.0015
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0082 0.0126 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0272
Onchocerca volvulus Huntingtin homolog 0.0071 0.0104 0.0897
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0029 0.0021 0.1607
Echinococcus granulosus intermediate filament protein 0.01 0.0161 0.0158
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0027 0.0017 0.0222
Loa Loa (eye worm) hypothetical protein 0.0347 0.0648 0.3698
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0082 0.0126 1
Toxoplasma gondii hypothetical protein 0.0049 0.0061 0.1027
Onchocerca volvulus 0.0362 0.0678 0.5968
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0058 0.0079 0.1524
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0129 0.0226
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0035 0.0061
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0022 0.0007 0.0001
Leishmania major cathepsin L-like protease 0.011 0.0181 0.0317
Echinococcus granulosus importin subunit beta 1 0.0022 0.0008 0.0006
Loa Loa (eye worm) hypothetical protein 0.004 0.0044 0.0237
Brugia malayi hypothetical protein 0.0071 0.0104 0.0582
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0006 0.0011
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0075 0.0112 0.063
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.2916 0.5711 0.5708
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0029 0.0021 0.0108
Trichomonas vaginalis glucosylceramidase, putative 0.0594 0.1134 0.1986
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0002 0.0004
Brugia malayi RNA recognition motif domain containing protein 0.0087 0.0136 0.0766
Schistosoma mansoni hypothetical protein 0.057 0.1087 0.1086
Echinococcus multilocularis neuropeptide receptor A26 0.026 0.0477 0.0471
Brugia malayi Latrophilin receptor protein 2 0.009 0.0142 0.08
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0035 0.0061
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0022 0.0008 0.0006
Plasmodium vivax SET domain protein, putative 0.0027 0.0017 0.101
Loa Loa (eye worm) hypothetical protein 0.0362 0.0678 0.3871
Trypanosoma brucei importin beta-1 subunit, putative 0.0022 0.0008 0.0007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0091 0.0143 0.0137
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0043 0.0048 0.0042
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0091 0.0143 0.0142
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.0324 0.0323
Loa Loa (eye worm) hypothetical protein 0.009 0.0142 0.08
Schistosoma mansoni alpha-glucosidase 0.0325 0.0605 0.0604
Loa Loa (eye worm) hypothetical protein 0.0037 0.0037 0.0199
Schistosoma mansoni hypothetical protein 0.024 0.0437 0.0436
Echinococcus granulosus lamin dm0 0.01 0.0161 0.0158
Trichomonas vaginalis glucosylceramidase, putative 0.0594 0.1134 0.1986
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0026 0.0045
Loa Loa (eye worm) runx1 0.0045 0.0054 0.0294
Loa Loa (eye worm) TAR-binding protein 0.0087 0.0136 0.0766
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Schistosoma mansoni intermediate filament proteins 0.01 0.0161 0.016
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0054 0.007 0.0115
Echinococcus granulosus expressed conserved protein 0.0072 0.0106 0.0104
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0031 0.0026 0.0134
Mycobacterium ulcerans lipase LipD 0.0036 0.0036 0.0626
Schistosoma mansoni hypothetical protein 0.0032 0.0027 0.0026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0091 0.0143 0.0805
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0091 0.0143 0.0141
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0054 0.007 0.119
Brugia malayi MH2 domain containing protein 0.0261 0.0479 0.2733
Schistosoma mansoni hypothetical protein 0.009 0.0142 0.0141
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0091 0.0143 0.0141
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0029 0.0021 0.0037
Onchocerca volvulus Bile acid receptor homolog 0.0091 0.0143 0.1242
Loa Loa (eye worm) hypothetical protein 0.0048 0.0059 0.0325
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0043 0.0037
Mycobacterium ulcerans hypothetical protein 0.0058 0.0079 0.1524
Loa Loa (eye worm) hypothetical protein 0.0053 0.0068 0.0376
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0029 0.0021 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0112 0.0196
Schistosoma mansoni patched 1 0.0033 0.0029 0.0028
Schistosoma mansoni nuclear hormone receptor 0.0091 0.0143 0.0142
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.007 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Plasmodium vivax vivapain-2 0.0029 0.0021 0.1365
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0091 0.0143 0.0805
Leishmania major cathepsin L-like protease 0.0029 0.0021 0.0037
Brugia malayi MAP kinase sur-1 0.0054 0.007 0.039
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0048 0.0059 0.0057
Echinococcus multilocularis lamin dm0 0.01 0.0161 0.0155
Echinococcus multilocularis tar DNA binding protein 0.0087 0.0136 0.013
Brugia malayi CXXC zinc finger family protein 0.0159 0.0277 0.1572
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0054 0.007 0.0123
Schistosoma mansoni alpha-glucosidase 0.0325 0.0605 0.0604
Giardia lamblia Kinase, CMGC MAPK 0.0054 0.007 0.0112
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Schistosoma mansoni aldehyde dehydrogenase 0.0035 0.0033 0.0032
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0058 0.0079 0.4735
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0006 0.0011
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0129 0.0226
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0035 0.0033 0.0058
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0905 0.1747 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0043 0.005 0.1044
Leishmania major cathepsin L-like protease 0.0029 0.0021 0.0037
Onchocerca volvulus 0.0091 0.0143 0.1242
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0036 0.0714
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0082 0.0126 0.2877
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0145 0.0249 0.0437
Brugia malayi ecdysone receptor 0.0043 0.0048 0.0265
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0049 0.0086
Brugia malayi tailless protein 0.0043 0.0048 0.0265
Trichomonas vaginalis glucosylceramidase, putative 0.0905 0.1747 0.306
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Entamoeba histolytica acyl-coA synthetase, putative 0.0058 0.0079 0.0138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0084 0.0129 0.0226
Schistosoma mansoni tar DNA-binding protein 0.0087 0.0136 0.0135
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0306 0.0567 0.0992
Echinococcus multilocularis lysosomal alpha glucosidase 0.0378 0.0708 0.0703
Brugia malayi AMP-binding enzyme family protein 0.0058 0.0079 0.0438
Brugia malayi glutaminase DH11.1 0.0263 0.0482 0.2747
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.007 0.0123
Brugia malayi hypothetical protein 0.0362 0.0678 0.3871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.009 0.0142 0.08
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0041 0.0045 0.0932
Toxoplasma gondii exonuclease III APE 0.0021 0.0006 0.0031
Loa Loa (eye worm) fibroinase 0.0029 0.0021 0.0108
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0905 0.1747 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0272
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.009 0.0142 0.0136
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0075 0.0112 0.011
Brugia malayi ecdysteroid receptor 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0027 0.0017 0.0083
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.005 0.0062 0.006
Trichomonas vaginalis esterase, putative 0.0036 0.0036 0.0063
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0036 0.0714
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0035 0.0061
Plasmodium falciparum cysteine proteinase falcipain 3 0.0029 0.0021 0.1607
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.0324 0.0322
Trypanosoma cruzi cysteine peptidase, putative 0.0029 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0193
Brugia malayi photoreceptor-specific nuclear receptor 0.0091 0.0143 0.0805
Echinococcus multilocularis ecdysone induced protein 78C 0.0091 0.0143 0.0137
Trichomonas vaginalis maltase-glucoamylase, putative 0.0084 0.0129 0.0226
Brugia malayi beta-lactamase 0.0036 0.0036 0.0193
Brugia malayi nuclear receptor NHR-88 0.0091 0.0143 0.0805
Loa Loa (eye worm) steroid hormone receptor 0.0091 0.0143 0.0805
Brugia malayi TAR-binding protein 0.0087 0.0136 0.0766
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0054 0.007 0.0123
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0043 0.0048 0.0046
Onchocerca volvulus Glucosylceramidase homolog 0.0594 0.1134 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0337 0.0628 0.0628
Echinococcus granulosus neuropeptide receptor A26 0.026 0.0477 0.0475
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0075 0.0112 0.0111
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.009 0.0142 0.0136
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0091 0.0143 0.0141
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0043 0.005 0.0915
Echinococcus granulosus thyroid hormone receptor alpha 0.0043 0.0048 0.0046
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.009 0.0142 0.014
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0036 0.2587
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0058 0.0322
Entamoeba histolytica acyl-CoA synthetase, putative 0.0058 0.0079 0.0138
Loa Loa (eye worm) hypothetical protein 0.0077 0.0115 0.0648
Toxoplasma gondii leucyl aminopeptidase LAP 0.0082 0.0126 0.2199
Loa Loa (eye worm) nuclear receptor NHR-67 0.0043 0.0048 0.0265
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0036 0.003
Leishmania major 4-coumarate:coa ligase-like protein 0.0058 0.0079 0.0138
Onchocerca volvulus 0.0029 0.0021 0.0166
Loa Loa (eye worm) RNA binding protein 0.0087 0.0136 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0022 0.0007 0.0019
Schistosoma mansoni cpg binding protein 0.0159 0.0277 0.0276
Loa Loa (eye worm) hypothetical protein 0.0071 0.0104 0.0582
Onchocerca volvulus 0.0218 0.0395 0.3467
Mycobacterium tuberculosis Conserved protein 0.0036 0.0036 0.0714
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0285 0.0526 0.3001
Loa Loa (eye worm) hypothetical protein 0.0048 0.0058 0.0322
Loa Loa (eye worm) transcription factor SMAD2 0.0261 0.0479 0.2733
Mycobacterium ulcerans aldehyde dehydrogenase 0.0035 0.0033 0.0572
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.024 0.0437 0.249
Schistosoma mansoni hypothetical protein 0.0195 0.0348 0.0347
Brugia malayi nuclear receptor NHR-67 0.0043 0.0048 0.0265
Echinococcus multilocularis microtubule associated protein 2 0.5093 1 1
Loa Loa (eye worm) hypothetical protein 0.01 0.0161 0.0908
Brugia malayi Pre-SET motif family protein 0.0166 0.029 0.1652
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0129 0.0226
Brugia malayi isocitrate dehydrogenase 0.0022 0.0007 0.0027
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0054 0.007 0.0123
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0082 0.0126 0.0221
Trichomonas vaginalis hypothetical protein 0.0019 0.0002 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0166 0.029 0.1652
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.0324 0.0323
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0061 0.0338
Loa Loa (eye worm) hypothetical protein 0.0048 0.0058 0.0322
Chlamydia trachomatis cytosol aminopeptidase 0.0082 0.0126 1
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.0181 0.0317
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0036 0.0035 0.0061
Echinococcus multilocularis dnaJ subfamily B 0.2258 0.4413 0.441
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0075 0.0112 0.0196
Leishmania major cathepsin L-like protease 0.0029 0.0021 0.0037
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0091 0.0143 0.0142
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0036 0.0714
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0054 0.007 0.0123
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0043 0.0048 0.0265
Echinococcus multilocularis cathepsin L cysteine protease 0.0029 0.0021 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0058 0.0079 0.0438
Brugia malayi calpain family protein 1 0.0053 0.0068 0.0376
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0035 0.0033 0.0031
Echinococcus multilocularis importin subunit beta 1 0.0022 0.0008 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0091 0.0143 0.0805
Brugia malayi Papain family cysteine protease containing protein 0.0029 0.0021 0.0108
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0006 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0053 0.0068 0.0376
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0082 0.0126 0.0213
Echinococcus granulosus ecdysone induced protein 78C 0.0091 0.0143 0.0141
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0029 0.0021 0.0108
Brugia malayi Steroid receptor seven-up type 2 0.0091 0.0143 0.0805
Trichomonas vaginalis alpha-glucosidase, putative 0.0031 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Loa Loa (eye worm) CXXC zinc finger family protein 0.0159 0.0277 0.1572
Loa Loa (eye worm) cytochrome P450 family protein 0.0052 0.0066 0.0365
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0031 0.0026 0.0045
Echinococcus multilocularis protein dispatched 1 0.0038 0.0038 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Echinococcus multilocularis cpg binding protein 0.0168 0.0294 0.0288
Brugia malayi nuclear hormone receptor 0.0043 0.0048 0.0265
Mycobacterium ulcerans hypothetical protein 0.0161 0.0282 0.5791
Loa Loa (eye worm) hypothetical protein 0.0048 0.0058 0.0322
Schistosoma mansoni lamin 0.01 0.0161 0.016
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0048 0.0047
Schistosoma mansoni hypothetical protein 0.2916 0.5711 0.571
Schistosoma mansoni nuclear receptor 0.0043 0.0048 0.0047
Trichomonas vaginalis alpha-glucosidase, putative 0.0084 0.0129 0.0226
Echinococcus granulosus mitogen activated protein kinase 3 0.0054 0.007 0.0068
Giardia lamblia Rrm3p helicase 0.2916 0.5711 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Loa Loa (eye worm) latrophilin receptor protein 2 0.009 0.0142 0.08
Loa Loa (eye worm) beta-lactamase 0.0036 0.0036 0.0193
Leishmania major cathepsin L-like protease 0.011 0.0181 0.0317
Leishmania major alpha glucosidase II subunit, putative 0.0084 0.0129 0.0226
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0233 0.0423 1
Onchocerca volvulus 0.0036 0.0036 0.0298
Echinococcus multilocularis cysteine protease 0.0029 0.0021 0.0015
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.005 0.0062 0.0056
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Brugia malayi AMP-binding enzyme family protein 0.0058 0.0079 0.0438
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0006 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0048 0.0058 0.0052
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0058 0.0079 0.1738
Schistosoma mansoni hypothetical protein 0.009 0.0142 0.0141
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0027 0.0017 0.0011
Trichomonas vaginalis glucosylceramidase, putative 0.0905 0.1747 0.306
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0036 0.0193
Mycobacterium ulcerans acyl-CoA synthetase 0.0058 0.0079 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0022 0.0007 0.0012
Brugia malayi steroid hormone receptor 0.0091 0.0143 0.0805
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0091 0.0143 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0058 0.0079 0.1524
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0091 0.0143 0.0805
Brugia malayi Calcitonin receptor-like protein seb-1 0.0285 0.0526 0.3001
Echinococcus granulosus GPCR family 2 0.009 0.0142 0.014
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0073 0.0072
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0031 0.0026 0.0045
Trichomonas vaginalis glucosylceramidase, putative 0.0594 0.1134 0.1986
Echinococcus granulosus Protein patched homolog 1 0.0033 0.0029 0.0027
Onchocerca volvulus Protein ultraspiracle homolog 0.0091 0.0143 0.1242
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0091 0.0143 0.0141
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0053 0.0069 0.0385
Echinococcus granulosus neuropeptide s receptor 0.026 0.0477 0.0475
Mycobacterium ulcerans hypothetical protein 0.0036 0.0036 0.0626
Brugia malayi hypothetical protein 0.0043 0.0048 0.0265
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0053 0.0068 0.0067
Schistosoma mansoni cathepsin F (C01 family) 0.0029 0.0021 0.002
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0036 0.0714
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0077 0.0115 0.0202
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0272
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0082 0.0126 0.0221
Brugia malayi nuclear hormone receptor family member nhr-6 0.0043 0.0048 0.0265
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0087 0.0136 0.0766
Trichomonas vaginalis glucosylceramidase, putative 0.0594 0.1134 0.1986
Onchocerca volvulus 0.0029 0.0021 0.0166
Schistosoma mansoni ap endonuclease 0.0021 0.0006 0.0005
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0075 0.0112 0.0196
Loa Loa (eye worm) glutaminase 2 0.0263 0.0482 0.2747
Loa Loa (eye worm) hypothetical protein 0.0253 0.0462 0.2635
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0183 0.0324 0.0323
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0021 0.0037
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0091 0.0143 0.0805
Echinococcus multilocularis Protein lozenge 0.0045 0.0054 0.0047
Loa Loa (eye worm) histone methyltransferase 0.005 0.0062 0.0345
Echinococcus multilocularis GPCR, family 2 0.009 0.0142 0.0136
Brugia malayi Niemann-Pick C1 protein precursor 0.0077 0.0115 0.0648
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.2916 0.5711 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0084 0.0129 0.2256
Brugia malayi hypothetical protein 0.002 0.0004 0.0013
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0036 0.0626
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0091 0.0143 0.0141
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0006 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Brugia malayi Intermediate filament tail domain containing protein 0.01 0.0161 0.0908
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0091 0.0143 0.0805
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.0181 0.0317
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0002 0.0001
Onchocerca volvulus 0.01 0.0161 0.14
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0091 0.0143 0.0805
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0006 0.0011
Echinococcus granulosus Niemann Pick C1 protein 0.0077 0.0115 0.0113
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0036 0.0063
Echinococcus multilocularis FTZ F1 alpha 0.0091 0.0143 0.0137
Onchocerca volvulus 0.0029 0.0021 0.0166
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0006 0.0003
Brugia malayi Isocitrate dehydrogenase 0.0022 0.0007 0.0027
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0035 0.0061
Loa Loa (eye worm) hypothetical protein 0.0043 0.005 0.0272
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0091 0.0143 0.0142
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0043 0.0048 0.0047
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Onchocerca volvulus 0.0043 0.0048 0.0408
Entamoeba histolytica hypothetical protein 0.0085 0.0132 0.0232
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0085 0.0132 0.013
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0183 0.0324 0.0322
Schistosoma mansoni importin beta-1 0.0022 0.0008 0.0007
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0378 0.0708 0.4047
Entamoeba histolytica hypothetical protein 0.0085 0.0132 0.0232
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Schistosoma mansoni cathepsin F (C01 family) 0.0029 0.0021 0.002
Schistosoma mansoni lamin 0.01 0.0161 0.016
Echinococcus multilocularis survival motor neuron protein 1 0.0347 0.0648 0.0642
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0091 0.0143 0.0805
Schistosoma mansoni cpg binding protein 0.0168 0.0294 0.0293
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.2916 0.5711 0.571
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.2916 0.5711 1
Brugia malayi Cathepsin L-like precursor 0.0029 0.0021 0.0108
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0027 0.0017 0.0016
Trichomonas vaginalis CMGC family protein kinase 0.0054 0.007 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0041 0.0045 0.0932
Trypanosoma cruzi cruzipain precursor, putative 0.011 0.0181 0.0317
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0036 0.0714
Brugia malayi Glycosyl hydrolases family 31 protein 0.0378 0.0708 0.4047
Trichomonas vaginalis maltase-glucoamylase, putative 0.0031 0.0026 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0029 0.0051
Leishmania major cysteine peptidase A (CPA) 0.0029 0.0021 0.0037
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0002 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Brugia malayi cytoplasmic intermediate filament protein 0.0053 0.0069 0.0385
Mycobacterium ulcerans glutaminase 0.0263 0.0482 1
Echinococcus granulosus calpain A 0.0055 0.0073 0.0071
Echinococcus multilocularis mitogen activated protein kinase 0.0054 0.007 0.0064
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0036 0.0063
Loa Loa (eye worm) hypothetical protein 0.0048 0.0058 0.0322
Echinococcus granulosus lamin 0.01 0.0161 0.0158
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0091 0.0143 0.0141
Loa Loa (eye worm) hypothetical protein 0.0091 0.0143 0.0805
Loa Loa (eye worm) cysteine protease 0.0029 0.0021 0.0108
Brugia malayi hypothetical protein 0.0253 0.0462 0.2635
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0035 0.0061
Loa Loa (eye worm) hypothetical protein 0.0195 0.0348 0.1982
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0048 0.0058 0.0322
Brugia malayi latrophilin 2 splice variant baaae 0.0195 0.0348 0.1982
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0006 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0183 0.0324 0.0318
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0022 0.0007 0.048
Onchocerca volvulus Huntingtin homolog 0.0071 0.0104 0.0897
Schistosoma mansoni aldehyde dehydrogenase 0.0035 0.0033 0.0032
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0084 0.0129 0.0226
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.0043 0.0042
Echinococcus granulosus Nuclear hormone receptor HR96 0.0043 0.0048 0.0046
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0085 0.0132 0.0126
Brugia malayi hypothetical protein 0.0048 0.0058 0.0322
Entamoeba histolytica cysteine proteinase, putative 0.0029 0.0021 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.011 0.0181 0.031
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0048 0.0058 0.0056
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0101 0.0162 0.0284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0082 0.0126 0.0221
Schistosoma mansoni survival motor neuron protein 0.0071 0.0104 0.0103
Schistosoma mansoni hypothetical protein 0.0032 0.0027 0.0026
Brugia malayi Nuclear hormone receptor E75 0.0043 0.0048 0.0265
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.01 0.0161 0.0908
Loa Loa (eye worm) DR-78 0.0043 0.0048 0.0265
Leishmania major cathepsin L-like protease 0.011 0.0181 0.0317
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0067 0.0118
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0006 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0183 0.0324 0.1844
Onchocerca volvulus 0.0029 0.0021 0.0166
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0078 0.0118 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0087 0.0136 0.0135
Schistosoma mansoni tar DNA-binding protein 0.0087 0.0136 0.0135
Trypanosoma cruzi hypothetical protein, conserved 0.0084 0.0129 0.0226
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0082 0.0126 1
Schistosoma mansoni ap endonuclease 0.0021 0.0006 0.0005
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0031 0.0026 0.0045
Echinococcus multilocularis isocitrate dehydrogenase 0.0022 0.0007 0.0001
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0036 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0029 0.0021 0.0037
Leishmania major hypothetical protein, conserved 0.002 0.0004 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Leishmania major cathepsin L-like protease 0.0029 0.0021 0.0037
Echinococcus multilocularis Niemann Pick C1 protein 0.011 0.018 0.0174
Brugia malayi Glycosyl hydrolases family 31 protein 0.0084 0.0129 0.0728
Brugia malayi RNA binding protein 0.0087 0.0136 0.0766
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0029 0.0021 0.0037
Brugia malayi Cathepsin L-like precursor 0.0029 0.0021 0.0108
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0183 0.0324 0.1844
Loa Loa (eye worm) hypothetical protein 0.002 0.0004 0.0013
Loa Loa (eye worm) hypothetical protein 0.0043 0.0048 0.0265
Brugia malayi Nuclear hormone receptor E75 0.0043 0.0048 0.0265
Entamoeba histolytica hypothetical protein 0.0085 0.0132 0.0232
Schistosoma mansoni hypothetical protein 0.057 0.1087 0.1086
Schistosoma mansoni nuclear hormone receptor 0.0043 0.0048 0.0047
Schistosoma mansoni alpha glucosidase 0.0084 0.0129 0.0128
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0036 0.0035
Echinococcus multilocularis lamin 0.01 0.0161 0.0155
Echinococcus granulosus Niemann Pick C1 protein 0.011 0.018 0.0178
Brugia malayi beta-lactamase family protein 0.0036 0.0036 0.0193
Echinococcus granulosus leucine aminopeptidase protein 0.0082 0.0126 0.0124
Brugia malayi nuclear receptor RXR 0.0048 0.0058 0.0322
Echinococcus multilocularis lysosomal alpha glucosidase 0.0378 0.0708 0.0703
Onchocerca volvulus 0.0037 0.0037 0.0307
Brugia malayi beta-lactamase family protein 0.0036 0.0036 0.0193
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0036 0.0035 0.0061
Mycobacterium tuberculosis Conserved protein 0.0036 0.0036 0.0714
Loa Loa (eye worm) hypothetical protein 0.0036 0.0036 0.0193
Loa Loa (eye worm) hypothetical protein 0.0046 0.0055 0.0304
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0054 0.007 0.039
Leishmania major mitochondrial DNA polymerase beta 0.0306 0.0567 0.0992
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0091 0.0143 0.0805
Loa Loa (eye worm) hypothetical protein 0.0048 0.0058 0.0322
Leishmania major cathepsin L-like protease 0.0029 0.0021 0.0037
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0043 0.0037
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0285 0.0526 0.3001
Schistosoma mansoni hypothetical protein 0.2258 0.4413 0.4413
Brugia malayi Pre-SET motif family protein 0.0027 0.0017 0.0083
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0091 0.0143 0.1242
Brugia malayi Nuclear hormone receptor-like 1 0.0048 0.0058 0.0322
Toxoplasma gondii isocitrate dehydrogenase 0.0022 0.0007 0.0045
Toxoplasma gondii cathepsin CPL 0.0029 0.0021 0.03

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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