Detailed information for compound 900154

Basic information

Technical information
  • TDR Targets ID: 900154
  • Name: N-(4-dimethylaminophenyl)-2,5-dimethylfuran-3 -carboxamide
  • MW: 258.316 | Formula: C15H18N2O2
  • H donors: 1 H acceptors: 1 LogP: 2.75 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1oc(c(c1)C(=O)Nc1ccc(cc1)N(C)C)C
  • InChi: 1S/C15H18N2O2/c1-10-9-14(11(2)19-10)15(18)16-12-5-7-13(8-6-12)17(3)4/h5-9H,1-4H3,(H,16,18)
  • InChiKey: YJPXDCWZYVTSHO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(4-dimethylaminophenyl)-2,5-dimethyl-furan-3-carboxamide
  • N-(4-dimethylaminophenyl)-2,5-dimethyl-3-furancarboxamide
  • N-(4-dimethylaminophenyl)-2,5-dimethyl-3-furamide
  • 6144-50-9
  • Oprea1_033380
  • Oprea1_191993
  • 2,5-Dimethyl-furan-3-carboxylic acid (4-dimethylamino-phenyl)-amide
  • BAS 02062814
  • CBMicro_047176
  • BIM-0047134.P001
  • EU-0006883
  • ZINC00194770

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus 7tm_1 domain containing protein 0.0015 0.1099 0.1787
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0015 0.1099 0.1583
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.109 0.5
Onchocerca volvulus 0.0015 0.1099 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.1099 0.1099
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0015 0.1099 0.1787
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni alpha-1 adrenergic receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0015 0.1099 0.1099
Brugia malayi Cytochrome P450 family protein 0.0015 0.109 0.109
Brugia malayi Dopamine receptor 0.0015 0.1099 0.1099
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Onchocerca volvulus 0.0015 0.1099 0.5
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.109 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.1099 0.1583
Echinococcus granulosus hypothetical protein 0.0015 0.1099 0.1787
Schistosoma mansoni biogenic amine receptor 0.0015 0.1099 0.1583
Schistosoma mansoni hypothetical protein 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.109 0.5
Brugia malayi putative neuropeptide receptor NPR1 0.0015 0.1099 0.1099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis serotonin receptor 0.0015 0.1099 0.1787
Schistosoma mansoni amine GPCR 0.0015 0.1099 0.1583
Echinococcus granulosus neuropeptide receptor 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.109 0.5
Brugia malayi G-protein coupled receptor 0.0015 0.1099 0.1099
Echinococcus multilocularis fmrfamide receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) cytochrome P450 family protein 0.0015 0.109 0.109
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.1099 0.1787
Onchocerca volvulus 0.0015 0.1099 0.5
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.1099 0.1787
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.1099 0.1583
Trypanosoma brucei cytochrome P450, putative 0.0053 1 1
Schistosoma mansoni amine GPCR 0.0015 0.1099 0.1583
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) neuropeptide F receptor 0.0015 0.1099 0.1099
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0015 0.1099 0.1099
Schistosoma mansoni myosin xvIII 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni hypothetical protein 0.0015 0.109 0.1569
Echinococcus granulosus alpha 1A adrenergic receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.1099 0.1099
Schistosoma mansoni histamine h1 receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Brugia malayi Dopamine receptor protein 1 0.0015 0.1099 0.1099
Echinococcus multilocularis fmrfamide receptor 0.0015 0.1099 0.1787
Schistosoma mansoni cytochrome P450 0.0015 0.109 0.1569
Schistosoma mansoni hypothetical protein 0.0015 0.1099 0.1583
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.109 0.1772
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Schistosoma mansoni adenoreceptor 0.0015 0.1099 0.1583
Echinococcus granulosus serotonin receptor 0.0015 0.1099 0.1787
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.1099 0.1787
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0015 0.1099 0.1099
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0036 0.6151 0.6151
Onchocerca volvulus 0.0015 0.1099 0.5
Echinococcus multilocularis g-protein coupled receptor 0.0015 0.1099 0.1787
Brugia malayi putative neuropeptide receptor 0.0015 0.1099 0.1099
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis orexin receptor type 2 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus g-protein coupled receptor 0.0015 0.1099 0.1787
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Schistosoma mansoni amine GPCR 0.0015 0.1099 0.1583
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.5581 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.1099 0.1787
Schistosoma mansoni hypothetical protein 0.0015 0.1099 0.1583
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus tm gpcr rhodopsin 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0015 0.1099 0.1099
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.109 0.5
Brugia malayi Cytochrome P450 family protein 0.0053 1 1
Echinococcus granulosus g protein coupled receptor 0.0015 0.1099 0.1787
Onchocerca volvulus 0.0015 0.1099 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus tachykinin peptides receptor 99D 0.0015 0.1099 0.1787
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0015 0.1099 0.1787
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0015 0.1099 0.1583
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0015 0.1099 0.1583
Echinococcus granulosus sex peptide receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Mycobacterium leprae Conserved hypothetical protein 0.0015 0.109 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.1099 0.1583
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0036 0.6151 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis neuropeptide FF receptor 2 0.0015 0.1099 0.1787
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.109 0.5
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0053 1 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0015 0.1099 0.1787
Echinococcus multilocularis neuropeptides capa receptor 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.109 0.5
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0015 0.1099 0.1787
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.1099 0.1787
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0015 0.1099 0.1787
Echinococcus granulosus neuropeptide s receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus allatostatin A receptor 0.0015 0.1099 0.1787
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0015 0.1099 0.5
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0015 0.1099 0.1787
Echinococcus granulosus orexin receptor type 2 0.0015 0.1099 0.1787
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0015 0.1099 0.1099
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0036 0.6151 0.6151
Brugia malayi RE15519p 0.0015 0.1099 0.1099
Echinococcus multilocularis allatostatin A receptor 0.0015 0.1099 0.1787
Echinococcus multilocularis neuropeptide receptor 0.0015 0.1099 0.1787
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0015 0.1099 0.1583
Echinococcus multilocularis g protein coupled receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus somatostatin receptor 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.109 0.5
Schistosoma mansoni neuropeptide receptor 0.0015 0.1099 0.1583
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Toxoplasma gondii cytochrome p450 superfamily protein 0.0015 0.109 0.5
Echinococcus granulosus neuropeptide receptor A26 0.0015 0.1099 0.1787
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.1099 0.1583
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni amine GPCR 0.0015 0.1099 0.1583
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 1 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0015 0.1099 0.1583
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Schistosoma mansoni neuropeptide receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Brugia malayi Dopamine receptor protein 2 0.0015 0.1099 0.1099
Loa Loa (eye worm) cytochrome P450 0.0015 0.109 0.109
Loa Loa (eye worm) G-protein coupled receptor 0.0015 0.1099 0.1099
Onchocerca volvulus 0.0015 0.1099 0.5
Echinococcus multilocularis neuropeptide receptor A26 0.0015 0.1099 0.1787
Leishmania major cytochrome p450-like protein 0.0053 1 1
Brugia malayi larval opioid receptor 0.0015 0.1099 0.1099
Echinococcus granulosus neuropeptides capa receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.109 0.5
Brugia malayi neuropeptide F receptor 0.0015 0.1099 0.1099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.109 0.5
Echinococcus multilocularis sex peptide receptor 0.0015 0.1099 0.1787
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.109 0.5
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.109 0.5
Brugia malayi ORL1-like opioid receptor 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0038 0.6401 0.6401
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.109 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus biogenic amine 5HT receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 1 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0036 0.6151 1
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.109 0.5
Echinococcus granulosus neuropeptide Y receptor 0.0015 0.1099 0.1787
Echinococcus multilocularis 0.0015 0.109 0.1772
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Schistosoma mansoni biogenic amine (5HT) receptor 0.0015 0.1099 0.1583
Onchocerca volvulus 0.0015 0.1099 0.5
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0015 0.1099 0.1787
Brugia malayi neuropeptide F receptor 0.0015 0.1099 0.1099
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.1099 0.1787
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.1099 0.1787
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.109 0.5
Trypanosoma cruzi cytochrome P450, putative 0.0053 1 1
Onchocerca volvulus 0.0015 0.1099 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Echinococcus granulosus dro:myosuppressin receptor 0.0015 0.1099 0.1787
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0015 0.1099 0.1583
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.1099 0.1787
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0015 0.1099 0.1787
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.109 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0015 0.1099 0.1787
Mycobacterium leprae putative cytochrome p450 0.0015 0.109 0.5
Loa Loa (eye worm) CYP4Cod1 0.0053 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0015 0.1099 0.1099
Onchocerca volvulus 0.0015 0.1099 0.5
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.109 0.5
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0015 0.1099 0.1099
Onchocerca volvulus Neuropeptide F receptor homolog 0.0015 0.1099 0.5
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.109 0.5
Schistosoma mansoni opsin-like receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Onchocerca volvulus 0.0015 0.1099 0.5
Brugia malayi Serotonin receptor 0.0015 0.1099 0.1099
Schistosoma mansoni neuropeptide F-like receptor 0.0015 0.1099 0.1583
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0015 0.1099 0.1787
Schistosoma mansoni voltage-gated potassium channel 0.004 0.6946 1
Brugia malayi follicle stimulating hormone receptor 0.0015 0.1099 0.1099
Echinococcus granulosus g protein coupled receptor 0.0015 0.1099 0.1787
Brugia malayi G-protein coupled receptor 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.109 0.5
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0034 0.5581 0.5
Brugia malayi Serotonin receptor 0.0015 0.1099 0.1099
Echinococcus granulosus G protein coupled receptor 139 0.0015 0.1099 0.1787
Echinococcus multilocularis G protein coupled receptor 139 0.0015 0.1099 0.1787
Schistosoma mansoni biogenic amine receptor 0.0015 0.1099 0.1583
Echinococcus granulosus fmrfamide receptor 0.0015 0.1099 0.1787
Onchocerca volvulus 0.0015 0.1099 0.5
Onchocerca volvulus 0.0015 0.1099 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Brugia malayi GnHR receptor homolog 0.0015 0.1099 0.1099
Echinococcus multilocularis dro:myosuppressin receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Echinococcus granulosus peptide allatostatin:somatostatin 0.0015 0.1099 0.1787
Onchocerca volvulus 0.0015 0.1099 0.5
Loa Loa (eye worm) hypothetical protein 0.0032 0.5007 0.5007
Echinococcus multilocularis neuropeptide receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0015 0.1099 0.1583
Onchocerca volvulus 0.0015 0.1099 0.5
Echinococcus multilocularis g protein coupled receptor 0.0015 0.1099 0.1787
Echinococcus granulosus neuropeptide receptor 0.0015 0.1099 0.1787
Brugia malayi AKH receptor 0.0015 0.1099 0.1099
Onchocerca volvulus 0.0015 0.1099 0.5
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0015 0.1099 0.1787
Onchocerca volvulus 0.0015 0.1099 0.5
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Brugia malayi G protein-coupled receptor 0.0015 0.1099 0.1099
Echinococcus granulosus 7TM GPCR rhodopsin 0.0015 0.1099 0.1787
Echinococcus multilocularis rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Brugia malayi sulfakinin receptor protein 0.0015 0.1099 0.1099
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0015 0.1099 0.1099
Brugia malayi G protein-coupled receptor F59B2.13 0.0015 0.1099 0.1099
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.109 0.5
Schistosoma mansoni hypothetical protein 0.0015 0.1099 0.1583
Schistosoma mansoni neuropeptide receptor 0.0015 0.1099 0.1583
Brugia malayi Cytochrome P450 family protein 0.0015 0.109 0.109
Echinococcus multilocularis g protein coupled receptor 0.0015 0.1099 0.1787
Echinococcus granulosus rhodopsin orphan GPCR 0.0015 0.1099 0.1787
Echinococcus granulosus g protein coupled receptor 0.0015 0.1099 0.1787
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0015 0.1099 0.1099
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0015 0.1099 0.1099
Loa Loa (eye worm) TYRA-2 protein 0.0015 0.1099 0.1099
Echinococcus multilocularis neuropeptide Y receptor 0.0015 0.1099 0.1787
Echinococcus multilocularis somatostatin receptor 0.0015 0.1099 0.1787
Onchocerca volvulus 0.0015 0.1099 0.5
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis serotonin receptor 0.0015 0.1099 0.1787
Schistosoma mansoni amine GPCR 0.0015 0.1099 0.1583
Schistosoma mansoni voltage-gated potassium channel 0.004 0.6946 1
Echinococcus multilocularis neuropeptide s receptor 0.0015 0.1099 0.1787
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Echinococcus multilocularis G-protein coupled receptor, putative 0.0015 0.1099 0.1787
Loa Loa (eye worm) melatonin receptor type 1A 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni biogenic amine receptor 0.0015 0.1099 0.1583
Brugia malayi Melatonin receptor type 1A 0.0015 0.1099 0.1099
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Brugia malayi hypothetical protein 0.0015 0.1099 0.1099
Trypanosoma cruzi cytochrome P450, putative 0.0053 1 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0015 0.1099 0.1583
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0015 0.1099 0.1787
Brugia malayi cytochrome P450 0.0015 0.109 0.109
Schistosoma mansoni opsin-like receptor 0.0015 0.1099 0.1583
Loa Loa (eye worm) hypothetical protein 0.0015 0.1099 0.1099
Schistosoma mansoni neuropeptide receptor 0.0015 0.1099 0.1583
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0015 0.1099 0.1787
Schistosoma mansoni opsin-like receptor 0.0015 0.1099 0.1583

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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