Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.2051 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1399 | 0.6802 | 0.6802 |
Loa Loa (eye worm) | hexokinase | 0.2051 | 1 | 1 |
Brugia malayi | Hexokinase family protein | 0.1287 | 0.6252 | 0.6252 |
Echinococcus granulosus | hexokinase type 2 | 0.2051 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0041 | 0.0144 | 0.0144 |
Toxoplasma gondii | hexokinase | 0.2051 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase type 2 | 0.2051 | 1 | 1 |
Schistosoma mansoni | hexokinase | 0.2051 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.2051 | 1 | 0.5 |
Trypanosoma brucei | hexokinase, putative | 0.2051 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.2051 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.0131 | 0.5 |
Leishmania major | hexokinase, putative | 0.2051 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0652 | 0.3139 | 0.3139 |
Loa Loa (eye worm) | hexokinase | 0.2051 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.2051 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.0131 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.2051 | 1 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.2051 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.2051 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0652 | 0.3139 | 0.3139 |
Onchocerca volvulus | 0.2051 | 1 | 1 | |
Echinococcus multilocularis | hexokinase | 0.2051 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0041 | 0.0144 | 0.0144 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0041 | 0.0144 | 0.0144 |
Leishmania major | hexokinase, putative | 0.2051 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.0635 | 0.3054 | 0.3054 |
Echinococcus granulosus | hexokinase | 0.2051 | 1 | 1 |
Loa Loa (eye worm) | hexokinase type II | 0.2051 | 1 | 1 |
Plasmodium falciparum | hexokinase | 0.2051 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0045 | 0.0163 | 0.0163 |
Onchocerca volvulus | 0.2051 | 1 | 1 | |
Trypanosoma cruzi | hexokinase, putative | 0.2051 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.2051 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.2051 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.1287 | 0.6252 | 0.6252 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0045 | 0.0163 | 0.0163 |
Entamoeba histolytica | hexokinase 2 | 0.2051 | 1 | 0.5 |
Echinococcus granulosus | hexokinase | 0.2051 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.0635 | 0.3054 | 0.3054 |
Brugia malayi | hexokinase type II | 0.0652 | 0.3139 | 0.3139 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0041 | 0.0144 | 0.0144 |
Echinococcus multilocularis | hexokinase | 0.2051 | 1 | 1 |
Plasmodium vivax | hexokinase, putative | 0.2051 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0118 | 0.0118 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.