Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.3537 | 0.3537 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0375 | 0.0375 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.5545 | 0.6108 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.3537 | 0.3537 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.8839 | 1 |
Echinococcus multilocularis | lamin | 0.003 | 0.3537 | 0.3735 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.003 | 0.3537 | 0.3537 |
Echinococcus multilocularis | musashi | 0.003 | 0.3537 | 0.3735 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.3537 | 0.3735 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.3537 | 0.3735 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.8839 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0375 | 0.0375 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.3537 | 0.3735 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.8839 | 0.8839 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0375 | 0.0375 |
Echinococcus granulosus | lamin | 0.003 | 0.3537 | 0.3735 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.5545 | 0.5545 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.3537 | 0.3735 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.8839 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.3397 | 0.3397 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.3537 | 0.3537 |
Schistosoma mansoni | lamin | 0.003 | 0.3537 | 0.3735 |
Schistosoma mansoni | lamin | 0.003 | 0.3537 | 0.3735 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.8839 | 1 |
Onchocerca volvulus | 0.003 | 0.3537 | 0.5 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.8839 | 1 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.3537 | 0.3537 |
Onchocerca volvulus | 0.003 | 0.3537 | 0.5 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0375 | 0.0375 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.8839 | 0.8839 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.8839 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.8839 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.5545 | 0.5545 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.