Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | heat shock transcription factor, putative | 0.0194 | 0.1571 | 0.5 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0194 | 0.1571 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.0461 | 0.0706 |
Loa Loa (eye worm) | carboxylesterase | 0.0525 | 0.6529 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0089 | 0 | 0.5 |
Entamoeba histolytica | heat shock transcription factor, putative | 0.0194 | 0.1571 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0089 | 0 | 0.5 |
Brugia malayi | HSF-type DNA-binding domain containing protein | 0.0194 | 0.1571 | 0.2405 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0758 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0525 | 0.6529 | 0.6529 |
Echinococcus multilocularis | acetylcholinesterase | 0.0525 | 0.6529 | 0.6529 |
Echinococcus granulosus | acetylcholinesterase | 0.0525 | 0.6529 | 0.6529 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0525 | 0.6529 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0525 | 0.6529 | 0.6529 |
Loa Loa (eye worm) | hypothetical protein | 0.0525 | 0.6529 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0089 | 0 | 0.5 |
Onchocerca volvulus | Heat shock factor protein 2 homolog | 0.0194 | 0.1571 | 1 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0758 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.1571 | 0.2405 |
Loa Loa (eye worm) | hypothetical protein | 0.0525 | 0.6529 | 1 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.0461 | 0.0706 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0525 | 0.6529 | 0.6529 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0089 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0089 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0525 | 0.6529 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0089 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0525 | 0.6529 | 0.6529 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0525 | 0.6529 | 0.6529 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.0461 | 0.0706 |
Brugia malayi | Carboxylesterase family protein | 0.0525 | 0.6529 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.