Detailed information for compound 902592

Basic information

Technical information
  • TDR Targets ID: 902592
  • Name: 4-bromo-N-naphthalen-1-ylbenzamide
  • MW: 326.187 | Formula: C17H12BrNO
  • H donors: 1 H acceptors: 1 LogP: 4.7 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1ccc(cc1)C(=O)Nc1cccc2c1cccc2
  • InChi: 1S/C17H12BrNO/c18-14-10-8-13(9-11-14)17(20)19-16-7-3-5-12-4-1-2-6-15(12)16/h1-11H,(H,19,20)
  • InChiKey: HRRXXGCANBDDNQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 4-Bromo-N-(1-naphthyl)benzamide
  • 4-Bromo-N-naphthalen-1-yl-benzamide
  • ZINC00225730
  • STK246917
  • Benzamide, 4-bromo-N-(2-naphthyl)-
  • BAS 00090567

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni glycogen phosphorylase 0.0104 0.0595 0.0595
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0045 0.0218 0.258
Loa Loa (eye worm) hexokinase 0.0489 0.3047 0.3047
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0094 0.006
Entamoeba histolytica glycogen phosphorylase, putative 0.0045 0.0218 0.0218
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Loa Loa (eye worm) peptidase family M13 containing protein 0.0083 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0104
Plasmodium vivax vivapain-2 0.0016 0.0034 0.003
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0027 0.0105 0.0105
Echinococcus multilocularis g-protein coupled receptor 0.0039 0.018 0.0147
Schistosoma mansoni DNA polymerase eta 0.0022 0.007 0.007
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.007 0.0036
Schistosoma mansoni RAR-like nuclear receptor 0.0051 0.0258 0.0258
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0026 0.0094 0.006
Echinococcus granulosus importin subunit beta 1 0.0035 0.0153 0.0153
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.018 0.018
Schistosoma mansoni zinc finger protein 0.0024 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0104
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Entamoeba histolytica glycogenphosphorylase, putative 0.0045 0.0218 0.0218
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0039 0.018 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Schistosoma mansoni hypothetical protein 0.0039 0.018 0.018
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0324 0.029
Schistosoma mansoni nuclear receptor 0.0024 0.0086 0.0086
Schistosoma mansoni glycogen phosphorylase 0.0045 0.0218 0.0218
Echinococcus granulosus glycogen phosphorylase 0.0104 0.0595 0.0595
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0024 0.0086 0.0052
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0039 0.018 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Onchocerca volvulus 0.0039 0.018 0.018
Mycobacterium ulcerans lipase LipD 0.0035 0.0153 0.1438
Brugia malayi hypothetical protein 0.0027 0.0104 0.0104
Onchocerca volvulus 0.0039 0.018 0.018
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0026 0.0094 0.0094
Mycobacterium tuberculosis Probable hydrolase 0.0035 0.0153 0.0648
Trichomonas vaginalis importin beta-1, putative 0.0028 0.0111 0.1862
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.007 0.0036
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0086 0.0086
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.0034 0.0034
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.007 0.1174
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.018 0.0147
Trypanosoma cruzi phospholipase A1, putative 0.0327 0.2011 0.1984
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0153 0.0119
Echinococcus multilocularis g protein coupled receptor 0.0039 0.018 0.0147
Brugia malayi nuclear receptor NHR-88 0.0051 0.0258 0.0258
Schistosoma mansoni biogenic amine (5HT) receptor 0.0039 0.018 0.018
Schistosoma mansoni nuclear hormone receptor 0.0051 0.0258 0.0258
Echinococcus granulosus neuropeptide receptor A26 0.0559 0.349 0.349
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0086 0.0052
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Trypanosoma brucei hexokinase, putative 0.1581 1 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0153 0.0153
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0027 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0065 0.0345 0.0345
Onchocerca volvulus 0.0327 0.2011 0.2011
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.018 0.018
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.007 0.007
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0051 0.0258 0.0225
Echinococcus granulosus biogenic amine 5HT receptor 0.0039 0.018 0.018
Echinococcus granulosus G protein coupled receptor 139 0.0039 0.018 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Echinococcus granulosus GTP binding nuclear protein Ran 0.0026 0.0094 0.0094
Onchocerca volvulus Hexokinase homolog 0.0992 0.6248 0.6248
Loa Loa (eye worm) steroid hormone receptor 0.0051 0.0258 0.0258
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0024 0.0086 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0051 0.0258 0.0258
Entamoeba histolytica glycogen phosphorylase, putative 0.0104 0.0595 0.0595
Plasmodium vivax importin-beta 2, putative 0.0035 0.0153 0.0149
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni opsin-like receptor 0.0039 0.018 0.018
Entamoeba histolytica hexokinase 2 0.1581 1 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Echinococcus multilocularis neuropeptide receptor 0.0039 0.018 0.0147
Echinococcus granulosus dna polymerase eta 0.0022 0.007 0.007
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.0327 0.2011 0.2011
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.0153 0.1438
Schistosoma mansoni hypothetical protein 0.0029 0.0117 0.0117
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0051 0.0258 0.0225
Schistosoma mansoni neprilysin-2 (M13 family) 0.0057 0.0291 0.0291
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.0036
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0039 0.018 0.018
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.0327 0.2011 0.2011
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0153 0.2563
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Echinococcus granulosus neuropeptide FF receptor 2 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Leishmania major cathepsin L-like protease 0.0062 0.0324 0.029
Echinococcus granulosus glycogen phosphorylase 0.0104 0.0595 0.0595
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Brugia malayi Melatonin receptor type 1A 0.0039 0.018 0.018
Leishmania major importin beta-1 subunit, putative 0.0028 0.0111 0.0077
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0026 0.0094 0.0464
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Onchocerca volvulus 0.1581 1 1
Echinococcus multilocularis allatostatin A receptor 0.0039 0.018 0.0147
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0153 0.2563
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0024 0.0086 0.0086
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0112 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0057 0.0291 0.0291
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0289 0.0256
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0324 0.029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.018 0.018
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.018 0.018
Onchocerca volvulus 0.0051 0.0258 0.0258
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0034 0.0034
Onchocerca volvulus 0.0039 0.018 0.018
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0045 0.0218 0.1162
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.014 0.0823 0.0823
Echinococcus multilocularis Glycosyl transferase, family 35 0.0104 0.0595 0.0563
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0258 0.0258
Echinococcus multilocularis neuropeptide s receptor 0.0559 0.349 0.3467
Loa Loa (eye worm) hypothetical protein 0.0503 0.3132 0.3132
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Echinococcus granulosus alpha 1A adrenergic receptor 0.0039 0.018 0.018
Echinococcus granulosus hypothetical protein 0.0039 0.018 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.018 0.018
Echinococcus granulosus hexokinase type 2 0.1581 1 1
Brugia malayi hypothetical protein 0.0024 0.0086 0.0086
Trichomonas vaginalis ran, putative 0.0026 0.0094 0.1583
Entamoeba histolytica hypothetical protein 0.0028 0.0111 0.0111
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Schistosoma mansoni alpha-1 adrenergic receptor 0.0039 0.018 0.018
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0039 0.018 0.018
Loa Loa (eye worm) glycogen phosphorylase 0.0104 0.0595 0.0595
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0027 0.0105 0.0105
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Loa Loa (eye worm) hypothetical protein 0.0677 0.4244 0.4244
Echinococcus granulosus dro:myosuppressin receptor 0.0039 0.018 0.018
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.018 0.018
Loa Loa (eye worm) DR-78 0.0024 0.0086 0.0086
Entamoeba histolytica glycogen phosphorylase, putative 0.0045 0.0218 0.0218
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0171 0.1933
Echinococcus granulosus hexokinase 0.1581 1 1
Schistosoma mansoni opsin-like receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Brugia malayi photoreceptor-specific nuclear receptor 0.0051 0.0258 0.0258
Echinococcus multilocularis sex peptide receptor 0.0039 0.018 0.0147
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.018 0.0147
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0039 0.018 0.018
Onchocerca volvulus 0.0056 0.0285 0.0285
Echinococcus granulosus 7tm_1 domain containing protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Brugia malayi neuropeptide F receptor 0.0039 0.018 0.018
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0324 0.029
Onchocerca volvulus Protein ultraspiracle homolog 0.0051 0.0258 0.0258
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus granulosus histone acetyltransferase KAT2B 0.0041 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Echinococcus granulosus serotonin receptor 0.0039 0.018 0.018
Loa Loa (eye worm) neuropeptide F receptor 0.0039 0.018 0.018
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0027 0.0104 0.0104
Trypanosoma brucei phospholipase A1, putative 0.0327 0.2011 0.199
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0051 0.0258 0.0258
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0039 0.018 0.018
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.018 0.018
Giardia lamblia Glycogen phosphorylase 0.0104 0.0595 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Brugia malayi G-protein coupled receptor 0.0039 0.018 0.018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.0036
Trypanosoma brucei hexokinase 0.1581 1 1
Brugia malayi nuclear hormone receptor family member nhr-6 0.0024 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0029 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0034 0.0572
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus granulosus g-protein coupled receptor 0.0039 0.018 0.018
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0027 0.0104 0.0104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Echinococcus granulosus peptide allatostatin:somatostatin 0.0039 0.018 0.018
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.018 0.018
Toxoplasma gondii hexokinase 0.1581 1 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0051 0.0258 0.0258
Brugia malayi nuclear receptor RXR 0.0024 0.0086 0.0086
Brugia malayi orphan nuclear receptor NR2E1 0.0024 0.0086 0.0086
Echinococcus multilocularis dna polymerase kappa 0.0022 0.007 0.0036
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.0153 0.0153
Schistosoma mansoni hypothetical protein 0.0029 0.0117 0.0117
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Onchocerca volvulus 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0051 0.0258 0.0225
Schistosoma mansoni neuropeptide receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus multilocularis FTZ F1 alpha 0.0051 0.0258 0.0225
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.0153 0.0126
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.0034 0.0572
Schistosoma mansoni amine GPCR 0.0039 0.018 0.018
Echinococcus multilocularis somatostatin receptor 0.0039 0.018 0.0147
Onchocerca volvulus Phospholipase A2 homolog 0.0271 0.1658 0.1658
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Brugia malayi Cathepsin L-like precursor 0.0016 0.0034 0.0034
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.007 0.0043
Brugia malayi beta-lactamase family protein 0.0035 0.0153 0.0153
Mycobacterium tuberculosis Conserved protein 0.0035 0.0153 0.0648
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0051 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Onchocerca volvulus 0.0035 0.0153 0.0153
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0051 0.0258 0.0258
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0051 0.0258 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0051 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0034 0.0034
Echinococcus multilocularis geminin 0.0164 0.0974 0.0943
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Leishmania major cathepsin L-like protease 0.0062 0.0324 0.029
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.007 0.0043
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.018 0.018
Schistosoma mansoni biogenic amine receptor 0.0039 0.018 0.018
Schistosoma mansoni ephrin receptor 0.0129 0.0753 0.0753
Echinococcus multilocularis serotonin receptor 0.0039 0.018 0.0147
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus granulosus g protein coupled receptor 0.0039 0.018 0.018
Loa Loa (eye worm) peptidase family M13 containing protein 0.0083 0.0459 0.0459
Onchocerca volvulus 0.0992 0.6248 0.6248
Brugia malayi Angiotensin-converting enzyme family protein 0.0736 0.4618 0.4618
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0041 0.0193 0.3247
Trichomonas vaginalis glycogen phosphorylase, putative 0.0104 0.0595 1
Brugia malayi Cathepsin L-like precursor 0.0016 0.0034 0.0034
Echinococcus multilocularis orexin receptor type 2 0.0039 0.018 0.0147
Entamoeba histolytica hexokinase 1 0.1581 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0085 0.0471 0.0471
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0104
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0086 0.0086
Brugia malayi ephrin receptor 1 precursor 0.0062 0.0323 0.0323
Onchocerca volvulus 0.0039 0.018 0.018
Schistosoma mansoni ran 0.0026 0.0094 0.0094
Echinococcus granulosus g protein coupled receptor 0.0039 0.018 0.018
Onchocerca volvulus 0.0039 0.018 0.018
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Trichomonas vaginalis glycogen phosphorylase, putative 0.0104 0.0595 1
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0112 0.0645 0.4506
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0039 0.018 0.0147
Brugia malayi Cathepsin L-like precursor 0.0016 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0057 0.0291 0.0291
Loa Loa (eye worm) ctsf protein 0.0016 0.0034 0.0034
Schistosoma mansoni retinoic acid receptor RXR 0.0051 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Treponema pallidum hexokinase (hxk) 0.1581 1 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Loa Loa (eye worm) fibroinase 0.0016 0.0034 0.0034
Brugia malayi Steroid receptor seven-up type 2 0.0051 0.0258 0.0258
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Entamoeba histolytica cysteine protease, putative 0.0016 0.0034 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Brugia malayi nuclear hormone receptor 0.0051 0.0258 0.0258
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0051 0.0258 0.0258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0027 0.0105 0.0105
Brugia malayi neuropeptide F receptor 0.0039 0.018 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.492 0.4903
Brugia malayi Phospholipase A2 family protein 0.0677 0.4244 0.4244
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Leishmania major cathepsin L-like protease 0.0062 0.0324 0.029
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.018 0.0147
Echinococcus granulosus cathepsin l1 0.0016 0.0034 0.0034
Schistosoma mansoni amine GPCR 0.0039 0.018 0.018
Brugia malayi G protein-coupled receptor F59B2.13 0.0039 0.018 0.018
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0153 0.0149
Echinococcus multilocularis glycogen phosphorylase 0.0104 0.0595 0.0563
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0051 0.0258 0.0258
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0051 0.0258 0.0225
Echinococcus granulosus allatostatin A receptor 0.0039 0.018 0.018
Onchocerca volvulus Cathepsin L homolog 0.0016 0.0034 0.0034
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Echinococcus multilocularis thyroid hormone receptor alpha 0.0051 0.0258 0.0225
Echinococcus granulosus nuclear receptor nhr 48 0.0024 0.0086 0.0086
Echinococcus granulosus fmrfamide receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.018 0.018
Onchocerca volvulus 0.0016 0.0034 0.0034
Echinococcus multilocularis snurportin 1 0.0372 0.2298 0.2272
Brugia malayi ORL1-like opioid receptor 0.0039 0.018 0.018
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.007 0.1174
Loa Loa (eye worm) hypothetical protein 0.1078 0.6799 0.6799
Brugia malayi Cathepsin L-like precursor 0.0016 0.0034 0.0034
Schistosoma mansoni opsin-like receptor 0.0039 0.018 0.018
Mycobacterium tuberculosis Probable lipase LipD 0.0035 0.0153 0.0648
Echinococcus multilocularis nuclear receptor nhr 48 0.0024 0.0086 0.0052
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0024 0.0086 0.0052
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0035 0.0153 0.0648
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0026 0.0094 0.006
Trypanosoma cruzi hexokinase, putative 0.1581 1 1
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0153 0.2563
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.018 0.018
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0039 0.018 0.018
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.007 0.007
Echinococcus multilocularis g protein coupled receptor 0.0039 0.018 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.007 0.007
Echinococcus multilocularis hexokinase 0.1581 1 1
Onchocerca volvulus 0.0327 0.2011 0.2011
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Onchocerca volvulus 0.0039 0.018 0.018
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.007 0.0043
Schistosoma mansoni steroid hormone receptor ad4bp 0.0051 0.0258 0.0258
Trichomonas vaginalis penicillin-binding protein, putative 0.0035 0.0153 0.2563
Loa Loa (eye worm) beta-lactamase 0.0035 0.0153 0.0153
Brugia malayi nuclear receptor RXR 0.0027 0.0104 0.0104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0039 0.018 0.0147
Echinococcus multilocularis dna polymerase eta 0.0022 0.007 0.0036
Echinococcus granulosus snurportin 1 0.0372 0.2298 0.2298
Brugia malayi Cathepsin L-like precursor 0.0016 0.0034 0.0034
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0027 0.0105 0.0105
Loa Loa (eye worm) G-protein coupled receptor 0.0039 0.018 0.018
Echinococcus granulosus FTZ F1 alpha 0.0051 0.0258 0.0258
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0026 0.0094 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0086 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Loa Loa (eye worm) nuclear hormone receptor 0.0024 0.0086 0.0086
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0041 0.0193 0.016
Brugia malayi larval opioid receptor 0.0039 0.018 0.018
Onchocerca volvulus 0.0035 0.0153 0.0153
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0153 0.0126
Trypanosoma cruzi importin beta-1 subunit, putative 0.0028 0.0111 0.0077
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0051 0.0258 0.0258
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.018 0.018
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0039 0.018 0.018
Echinococcus granulosus hexokinase 0.1581 1 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0039 0.018 0.018
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.0153 0.0153
Echinococcus granulosus orexin receptor type 2 0.0039 0.018 0.018
Mycobacterium tuberculosis Probable lipase LipE 0.0035 0.0153 0.0648
Onchocerca volvulus 0.0327 0.2011 0.2011
Schistosoma mansoni neprilysin 0.0029 0.0117 0.0117
Echinococcus granulosus neuropeptide receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0039 0.018 0.0147
Schistosoma mansoni adenoreceptor 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0153 0.0119
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.007 0.0043
Loa Loa (eye worm) hypothetical protein 0.0085 0.0471 0.0471
Onchocerca volvulus 0.0039 0.018 0.018
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0039 0.018 0.018
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0171 0.0171
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0736 0.4618 0.4618
Echinococcus multilocularis neuropeptide FF receptor 2 0.0039 0.018 0.0147
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0104 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0258 0.0258
Onchocerca volvulus Phospholipase A2 homolog 0.0677 0.4244 0.4244
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0051 0.0258 0.0258
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0171 0.0138
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0026 0.0094 0.009
Echinococcus granulosus biogenic amine 5HT receptor 0.0039 0.018 0.018
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0039 0.018 0.0147
Echinococcus granulosus ecdysone induced protein 78C 0.0051 0.0258 0.0258
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0034 0.0034
Brugia malayi RNA, U transporter 1 0.0099 0.0562 0.0562
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0035 0.0153 0.0648
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Brugia malayi hypothetical protein 0.0027 0.0104 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0258 0.0258
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.0153 0.0153
Leishmania major phospholipase A1, putative 0.0327 0.2011 0.1984
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0039 0.018 0.0147
Brugia malayi AKH receptor 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0039 0.018 0.018
Plasmodium falciparum importin beta, putative 0.0035 0.0153 0.0119
Echinococcus multilocularis fmrfamide receptor 0.0039 0.018 0.0147
Echinococcus multilocularis endothelin converting enzyme 1 0.0112 0.0645 0.0613
Trypanosoma cruzi phospholipase A2-like protein, putative 0.015 0.0885 0.0854
Trichomonas vaginalis esterase, putative 0.0035 0.0153 0.2563
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0039 0.018 0.018
Echinococcus granulosus tachykinin peptides receptor 99D 0.0039 0.018 0.018
Trypanosoma brucei unspecified product 0.0022 0.007 0.0043
Onchocerca volvulus 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Onchocerca volvulus 0.0016 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Loa Loa (eye worm) hexokinase type II 0.1581 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.018 0.018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0111 0.1862
Echinococcus granulosus neuropeptide s receptor 0.0559 0.349 0.349
Brugia malayi ecdysone receptor 0.0024 0.0086 0.0086
Echinococcus multilocularis neuropeptide receptor 0.0039 0.018 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0051 0.0258 0.0258
Loa Loa (eye worm) TK/EPH protein kinase 0.0164 0.0976 0.0976
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Schistosoma mansoni importin beta-1 0.0035 0.0153 0.0153
Leishmania major GTP-binding protein, putative 0.0026 0.0094 0.006
Schistosoma mansoni biogenic amine receptor 0.0039 0.018 0.018
Echinococcus multilocularis glycogen phosphorylase 0.0104 0.0595 0.0563
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni amine GPCR 0.0039 0.018 0.018
Onchocerca volvulus 0.1581 1 1
Toxoplasma gondii HEAT repeat-containing protein 0.0035 0.0153 0.0119
Leishmania major hexokinase, putative 0.1581 1 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0086 0.0086
Onchocerca volvulus Cathepsin F homolog 0.0016 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.018 0.0147
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0039 0.018 0.018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.0036
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni hypothetical protein 0.0029 0.0117 0.0117
Mycobacterium ulcerans beta-lactamase 0.0035 0.0153 0.1438
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0041 0.0193 0.016
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.007 0.007
Schistosoma mansoni nuclear receptor nhr-48 0.0024 0.0086 0.0086
Brugia malayi nuclear receptor NHR-88 0.0024 0.0086 0.0086
Mycobacterium ulcerans zinc metalloprotease 0.0112 0.0645 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0039 0.018 0.0147
Echinococcus granulosus 7TM GPCR rhodopsin 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Loa Loa (eye worm) melatonin receptor type 1A 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0022 0.007 0.007
Plasmodium vivax vivapain-2 0.0016 0.0034 0.003
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.018 0.0147
Loa Loa (eye worm) hypothetical protein 0.0083 0.0459 0.0459
Trypanosoma brucei importin beta-1 subunit, putative 0.0035 0.0153 0.0126
Schistosoma mansoni biogenic amine (5HT) receptor 0.0039 0.018 0.018
Echinococcus multilocularis G-protein coupled receptor, putative 0.0039 0.018 0.0147
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Echinococcus granulosus ephrin type A receptor 4 A 0.0129 0.0753 0.0753
Schistosoma mansoni hypothetical protein 0.0372 0.2298 0.2298
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0024 0.0086 0.0086
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0051 0.0258 0.0258
Loa Loa (eye worm) zinc metallopeptidase 4 0.0027 0.0105 0.0105
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0258 0.0225
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0026 0.0094 0.006
Loa Loa (eye worm) hypothetical protein 0.0083 0.0459 0.0459
Brugia malayi carbohydrate phosphorylase 0.0104 0.0595 0.0595
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0028 0.0111 0.1862
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0051 0.0258 0.0258
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni neuropeptide f receptor 76f 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Mycobacterium leprae probable zinc metalloprotease 0.0112 0.0645 1
Schistosoma mansoni glycogen phosphorylase 0.0104 0.0595 0.0595
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0051 0.0258 0.0225
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Brugia malayi nuclear hormone receptor family member odr-7 0.0024 0.0086 0.0086
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0039 0.018 0.0147
Schistosoma mansoni coup transcription factor 0.0051 0.0258 0.0258
Onchocerca volvulus 0.0016 0.0034 0.0034
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0024 0.0086 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0029 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus granulosus geminin 0.0164 0.0974 0.0974
Onchocerca volvulus 0.0035 0.0153 0.0153
Loa Loa (eye worm) hexokinase 0.1581 1 1
Echinococcus granulosus sex peptide receptor 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0085 0.0471 0.0471
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.007 0.007
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Echinococcus multilocularis hexokinase 0.1581 1 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.0153 0.0119
Schistosoma mansoni hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni hypothetical protein 0.0164 0.0974 0.0974
Echinococcus multilocularis serotonin receptor 0.0039 0.018 0.0147
Onchocerca volvulus 0.0016 0.0034 0.0034
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.0153 0.1438
Schistosoma mansoni hypothetical protein 0.0029 0.0117 0.0117
Brugia malayi Dopamine receptor protein 2 0.0039 0.018 0.018
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Mycobacterium tuberculosis Probable esterase LipL 0.0035 0.0153 0.0648
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0027 0.0104 0.0104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.024 0.0206
Brugia malayi Dopamine receptor protein 1 0.0039 0.018 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Echinococcus granulosus neuropeptide receptor 0.0039 0.018 0.018
Trichomonas vaginalis D-aminoacylase, putative 0.0035 0.0153 0.2563
Echinococcus granulosus dna polymerase kappa 0.0022 0.007 0.007
Brugia malayi tailless protein 0.0024 0.0086 0.0086
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0104 0.0104
Schistosoma mansoni histamine h1 receptor 0.0039 0.018 0.018
Schistosoma mansoni hypothetical protein 0.0164 0.0974 0.0974
Brugia malayi hexokinase type II 0.0503 0.3132 0.3132
Echinococcus multilocularis ephrin type A receptor 4 A 0.0129 0.0753 0.0722
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0039 0.018 0.0147
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0024 0.0086 0.0052
Trypanosoma cruzi hexokinase, putative 0.1581 1 1
Onchocerca volvulus 0.0039 0.018 0.018
Onchocerca volvulus 0.0016 0.0034 0.0034
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0039 0.018 0.018
Schistosoma mansoni myosin xvIII 0.0039 0.018 0.018
Mycobacterium ulcerans hypothetical protein 0.0035 0.0153 0.1438
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0039 0.018 0.018
Entamoeba histolytica Ran family GTPase 0.0026 0.0094 0.0094
Brugia malayi Tachykinin-like peptides receptor 99D 0.0039 0.018 0.018
Brugia malayi beta-lactamase 0.0035 0.0153 0.0153
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0051 0.0258 0.0258
Brugia malayi Peptidase family M13 containing protein 0.0112 0.0645 0.0645
Onchocerca volvulus 0.1581 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Onchocerca volvulus 0.0016 0.0034 0.0034
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0039 0.018 0.0147
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.0034 0.0034
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0039 0.018 0.0147
Loa Loa (eye worm) hypothetical protein 0.0016 0.0034 0.0034
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0027 0.0104 0.007
Echinococcus multilocularis fmrfamide receptor 0.0039 0.018 0.0147
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) cysteine protease 0.0016 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0085 0.0471 0.0471
Onchocerca volvulus Bile acid receptor homolog 0.0051 0.0258 0.0258
Schistosoma mansoni hexokinase 0.1581 1 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Mycobacterium tuberculosis Conserved protein 0.0035 0.0153 0.0648
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0039 0.018 0.018
Echinococcus granulosus g protein coupled receptor 0.0039 0.018 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Schistosoma mansoni nuclear hormone receptor 0.0024 0.0086 0.0086
Onchocerca volvulus 0.0024 0.0086 0.0086
Chlamydia trachomatis glycogen phosphorylase 0.0104 0.0595 0.5
Loa Loa (eye worm) hypothetical protein 0.0085 0.0471 0.0471
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0039 0.018 0.018
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.018 0.018
Loa Loa (eye worm) hexokinase 0.0992 0.6248 0.6248
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Onchocerca volvulus 0.0024 0.0086 0.0086
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0041 0.0193 0.0189
Schistosoma mansoni neuropeptide receptor 0.0039 0.018 0.018
Echinococcus granulosus Glycosyl transferase family 35 0.0104 0.0595 0.0595
Schistosoma mansoni endothelin-converting enzyme-related 0.0027 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Trypanosoma cruzi phospholipase A2-like protein, putative 0.015 0.0885 0.0854
Brugia malayi Serotonin receptor 0.0039 0.018 0.018
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0024 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0324 0.029
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0051 0.0258 0.0258
Schistosoma mansoni amine GPCR 0.0039 0.018 0.018
Echinococcus multilocularis hexokinase type 2 0.1581 1 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0039 0.018 0.018
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Echinococcus granulosus neuropeptide Y receptor 0.0039 0.018 0.018
Echinococcus multilocularis G protein coupled receptor 139 0.0039 0.018 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0051 0.0258 0.0258
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0051 0.0258 0.0258
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.018 0.018
Brugia malayi Hexokinase family protein 0.0992 0.6248 0.6248
Entamoeba histolytica glycogen phosphorylase, putative 0.0104 0.0595 0.0595
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0024 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0034 0.0034
Brugia malayi Importin beta-1 subunit 0.0035 0.0153 0.0153
Onchocerca volvulus 0.0039 0.018 0.018
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0051 0.0258 0.0258
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.018 0.018
Brugia malayi ecdysteroid receptor 0.0051 0.0258 0.0258
Brugia malayi putative neuropeptide receptor 0.0039 0.018 0.018
Echinococcus granulosus neuropeptides capa receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Echinococcus granulosus hexokinase 0.1581 1 1
Brugia malayi sulfakinin receptor protein 0.0039 0.018 0.018
Echinococcus multilocularis rhodopsin orphan GPCR 0.0039 0.018 0.0147
Brugia malayi Dopamine receptor 0.0039 0.018 0.018
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0026 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0112 0.0645 0.0645
Schistosoma mansoni ran 0.0026 0.0094 0.0094
Brugia malayi beta-lactamase family protein 0.0035 0.0153 0.0153
Schistosoma mansoni growth hormone secretagogue receptor 0.0039 0.018 0.018
Echinococcus multilocularis ecdysone induced protein 78C 0.0051 0.0258 0.0225
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Loa Loa (eye worm) hypothetical protein 0.0083 0.0459 0.0459
Loa Loa (eye worm) hypothetical protein 0.0128 0.0744 0.0744
Onchocerca volvulus 0.0128 0.0744 0.0744
Onchocerca volvulus 0.0039 0.018 0.018
Trypanosoma cruzi phospholipase A1, putative 0.0327 0.2011 0.1984
Schistosoma mansoni neuropeptide F-like receptor 0.0039 0.018 0.018
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.007 0.0043
Toxoplasma gondii peptidase family M13 protein 0.0112 0.0645 0.0613
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Echinococcus granulosus Nuclear hormone receptor HR96 0.0024 0.0086 0.0086
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.0034 0.0572
Schistosoma mansoni thyroid hormone receptor 0.0051 0.0258 0.0258
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0039 0.018 0.018
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0024 0.0086 0.0052
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.014 0.0823 0.0791
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0051 0.0258 0.0258
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.0034 0.0034
Leishmania major DNA polymerase kappa, putative 0.0022 0.007 0.0036
Trypanosoma brucei hexokinase 0.1581 1 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0039 0.018 0.018
Plasmodium falciparum hexokinase 0.1581 1 1
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0051 0.0258 0.0258
Brugia malayi RE15519p 0.0039 0.018 0.018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0051 0.0258 0.0258
Brugia malayi acetyltransferase, GNAT family protein 0.014 0.0823 0.0823
Brugia malayi Hexokinase family protein 0.1581 1 1
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0372 0.2298 0.2298
Loa Loa (eye worm) hexokinase 0.1581 1 1
Onchocerca volvulus 0.0016 0.0034 0.0034
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0051 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0112 0.0645 0.0645
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0039 0.018 0.018
Brugia malayi hypothetical protein 0.0039 0.018 0.018
Schistosoma mansoni neuropeptide receptor 0.0039 0.018 0.018
Brugia malayi Cathepsin L-like precursor 0.0016 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0051 0.0258 0.0258
Mycobacterium tuberculosis Conserved protein 0.0035 0.0153 0.0648
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0024 0.0086 0.0086
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0051 0.0258 0.0258
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0057 0.0291 0.0291
Brugia malayi MH2 domain containing protein 0.0115 0.0666 0.0666
Brugia malayi hypothetical protein 0.0024 0.0086 0.0086
Schistosoma mansoni amine GPCR 0.0039 0.018 0.018
Leishmania major hypothetical protein, conserved 0.0035 0.0153 0.0119
Echinococcus granulosus histone acetyltransferase KAT2B 0.0136 0.0798 0.0798
Loa Loa (eye worm) hypothetical protein 0.0271 0.1658 0.1658
Echinococcus multilocularis neuropeptides capa receptor 0.0039 0.018 0.0147
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0035 0.0153 0.0648
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0039 0.018 0.018
Brugia malayi GnHR receptor homolog 0.0039 0.018 0.018
Onchocerca volvulus Neuropeptide F receptor homolog 0.0039 0.018 0.018
Onchocerca volvulus 0.0039 0.018 0.018
Loa Loa (eye worm) TYRA-2 protein 0.0039 0.018 0.018
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0026 0.0094 0.0068
Loa Loa (eye worm) hypothetical protein 0.0083 0.0459 0.0459
Brugia malayi conserved hypotetical protein 0.0024 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0035 0.0153 0.0153
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0104 0.0104
Echinococcus multilocularis neuropeptide Y receptor 0.0039 0.018 0.0147
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0112 0.0645 0.0645
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0222 0.1346 1
Echinococcus multilocularis neuropeptide receptor A26 0.0559 0.349 0.3467
Schistosoma mansoni hypothetical protein 0.0039 0.018 0.018
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.0666 0.0666
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.0034 0.0572
Onchocerca volvulus 0.0039 0.018 0.018
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.007 0.0036
Brugia malayi steroid hormone receptor 0.0051 0.0258 0.0258
Echinococcus granulosus endothelin converting enzyme 1 0.0112 0.0645 0.0645
Loa Loa (eye worm) hypothetical protein 0.0039 0.018 0.018
Trichomonas vaginalis bromodomain-containing protein, putative 0.0041 0.0193 0.3247
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Schistosoma mansoni neuropeptide receptor 0.0039 0.018 0.018
Schistosoma mansoni biogenic amine receptor 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0056 0.0285 0.0285
Schistosoma mansoni hypothetical protein 0.0029 0.0117 0.0117
Brugia malayi nuclear receptor NHR-67 0.0024 0.0086 0.0086
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.0666 0.0666
Onchocerca volvulus 0.0039 0.018 0.018
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0051 0.0258 0.0258
Toxoplasma gondii ABC1 family protein 0.0035 0.0153 0.0119
Echinococcus multilocularis importin subunit beta 1 0.0035 0.0153 0.0119
Loa Loa (eye worm) acetyltransferase 0.014 0.0823 0.0823
Brugia malayi putative neuropeptide receptor NPR1 0.0039 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0027 0.0104 0.0104
Brugia malayi Nuclear hormone receptor-like 1 0.0051 0.0258 0.0258
Echinococcus multilocularis hexokinase 0.1581 1 1
Loa Loa (eye worm) nuclear receptor NHR-67 0.0024 0.0086 0.0086
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.007 0.0036
Onchocerca volvulus 0.0039 0.018 0.018
Leishmania major DNA polymerase eta, putative 0.0022 0.007 0.0036
Loa Loa (eye worm) hypothetical protein 0.0503 0.3132 0.3132
Loa Loa (eye worm) hypothetical protein 0.0085 0.0471 0.0471
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0039 0.018 0.0147
Brugia malayi G-protein coupled receptor 0.0039 0.018 0.018
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0051 0.0258 0.0258
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0051 0.0258 0.0258
Brugia malayi peptidase family M13 containing protein 0.0027 0.0105 0.0105
Leishmania major hexokinase, putative 0.1581 1 1
Onchocerca volvulus Glycogen phosphorylase homolog 0.0104 0.0595 0.0595
Echinococcus granulosus somatostatin receptor 0.0039 0.018 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0324 0.0298
Loa Loa (eye worm) hypothetical protein 0.0024 0.0086 0.0086
Brugia malayi Nuclear hormone receptor E75 0.0024 0.0086 0.0086
Brugia malayi follicle stimulating hormone receptor 0.0039 0.018 0.018
Echinococcus granulosus tm gpcr rhodopsin 0.0039 0.018 0.018
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0039 0.018 0.018
Echinococcus granulosus rhodopsin orphan GPCR 0.0039 0.018 0.018
Brugia malayi G protein-coupled receptor 0.0039 0.018 0.018
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0112 0.0645 0.0645
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0051 0.0258 0.0258
Brugia malayi Serotonin receptor 0.0039 0.018 0.018
Plasmodium vivax hexokinase, putative 0.1581 1 1
Onchocerca volvulus 0.0039 0.018 0.018
Echinococcus granulosus thyroid hormone receptor alpha 0.0024 0.0086 0.0086
Brugia malayi nuclear hormone receptor 0.0024 0.0086 0.0086
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0057 0.0291 0.0291
Brugia malayi Hexokinase family protein 0.0489 0.3047 0.3047
Echinococcus multilocularis g protein coupled receptor 0.0039 0.018 0.0147
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0051 0.0258 0.0258
Schistosoma mansoni nuclear receptor 0.0024 0.0086 0.0086
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0051 0.0258 0.0258

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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