Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Hexokinase family protein | 0.1116 | 0.6249 | 0.6249 |
Echinococcus granulosus | hexokinase type 2 | 0.1779 | 1 | 1 |
Onchocerca volvulus | 0.1779 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.1213 | 0.68 | 0.68 |
Loa Loa (eye worm) | hexokinase | 0.1779 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.3134 | 0.3134 |
Loa Loa (eye worm) | hexokinase | 0.1779 | 1 | 1 |
Entamoeba histolytica | hexokinase 1 | 0.1779 | 1 | 0.5 |
Treponema pallidum | hexokinase (hxk) | 0.1779 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0038 | 0.0147 | 0.5 |
Echinococcus multilocularis | hexokinase | 0.1779 | 1 | 1 |
Echinococcus granulosus | hexokinase | 0.1779 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.004 | 0.0162 | 0.0162 |
Toxoplasma gondii | hexokinase | 0.1779 | 1 | 0.5 |
Schistosoma mansoni | hexokinase | 0.1779 | 1 | 1 |
Echinococcus multilocularis | hexokinase type 2 | 0.1779 | 1 | 1 |
Trypanosoma brucei | hexokinase | 0.1779 | 1 | 0.5 |
Trypanosoma brucei | hexokinase, putative | 0.1779 | 1 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0038 | 0.0147 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1779 | 1 | 0.5 |
Leishmania major | hexokinase, putative | 0.1779 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.055 | 0.3049 | 0.3049 |
Echinococcus granulosus | hexokinase | 0.1779 | 1 | 1 |
Loa Loa (eye worm) | hexokinase type II | 0.1779 | 1 | 1 |
Plasmodium falciparum | hexokinase | 0.1779 | 1 | 0.5 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0044 | 0.0183 | 0.0183 |
Onchocerca volvulus | 0.1779 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0565 | 0.3134 | 0.3134 |
Onchocerca volvulus | 0.1779 | 1 | 1 | |
Echinococcus multilocularis | hexokinase | 0.1779 | 1 | 1 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.004 | 0.0162 | 0.0162 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.004 | 0.0162 | 0.0162 |
Leishmania major | hexokinase, putative | 0.1779 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0132 | 0.0132 |
Plasmodium vivax | hexokinase, putative | 0.1779 | 1 | 0.5 |
Trypanosoma cruzi | hexokinase, putative | 0.1779 | 1 | 0.5 |
Trypanosoma brucei | hexokinase | 0.1779 | 1 | 0.5 |
Brugia malayi | Hexokinase family protein | 0.1779 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.1116 | 0.6249 | 0.6249 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0044 | 0.0183 | 0.0183 |
Echinococcus granulosus | hexokinase | 0.1779 | 1 | 1 |
Loa Loa (eye worm) | hexokinase | 0.055 | 0.3049 | 0.3049 |
Entamoeba histolytica | hexokinase 2 | 0.1779 | 1 | 0.5 |
Brugia malayi | hexokinase type II | 0.0565 | 0.3134 | 0.3134 |
Echinococcus multilocularis | hexokinase | 0.1779 | 1 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.004 | 0.0162 | 0.0162 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.