Detailed information for compound 904762

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 450.548 | Formula: C26H31FN4O2
  • H donors: 0 H acceptors: 3 LogP: 3.46 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)C(=O)N1CC[C@@H]2[C@H](C1)CCCN2C(=O)C1CCCN(C1)c1ccccn1
  • InChi: 1S/C26H31FN4O2/c27-22-10-8-19(9-11-22)25(32)30-16-12-23-20(17-30)5-4-15-31(23)26(33)21-6-3-14-29(18-21)24-7-1-2-13-28-24/h1-2,7-11,13,20-21,23H,3-6,12,14-18H2/t20-,21?,23+/m1/s1
  • InChiKey: IXFOFZVHLQIXCZ-LYLQVHRMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus Putative pyridoxal kinase 0.0131 0.0483 0.0407
Leishmania major tagatose-6-phosphate kinase-like protein 0.0131 0.0483 0.1049
Schistosoma mansoni bromodomain containing protein 0.0008 0.0003 0.0005
Schistosoma mansoni regulator of G protein signaling 0.002 0.0048 0.0106
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0009 0.0007 0.0006
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0021 0.0021
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0509 0.114
Schistosoma mansoni hypothetical protein 0.0504 0.1939 0.4351
Mycobacterium tuberculosis Adenosine kinase 0.0131 0.0483 1
Loa Loa (eye worm) hypothetical protein 0.0446 0.1713 0.1713
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.004 0.0881
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0057 0.0057
Brugia malayi Cyclic-nucleotide gated cation channel 0.0007 0.0001 0.0001
Loa Loa (eye worm) acetyltransferase 0.015 0.0559 0.0559
Brugia malayi MH2 domain containing protein 0.0008 0.0004 0.0004
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0004 0.0003
Trypanosoma cruzi nucleobase transporter, putative 0.0446 0.1713 0.3821
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.015 0.0559 0.1252
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0119 0.0119
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0037 0.0036
Chlamydia trachomatis pyruvate kinase 0.0034 0.0105 1
Trypanosoma cruzi nucleoside transporter-like, putative 0.0446 0.1713 0.3821
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0446 0.1713 0.3821
Trypanosoma brucei purine nucleoside transporter 0.0446 0.1713 0.3821
Schistosoma mansoni survival motor neuron protein 0.0049 0.0164 0.0366
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.007 0.3288
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0048
Schistosoma mansoni axis inhibition protein axin 0.002 0.0048 0.0106
Loa Loa (eye worm) hypothetical protein 0.0034 0.0105 0.0105
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0007 0.0001 0.0001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0024 0.0023
Brugia malayi hypothetical protein 0.002 0.0048 0.0048
Onchocerca volvulus 0.1018 0.3945 0.3896
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0037 0.0036
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0446 0.1713 0.3821
Leishmania major putative PfkB family sugar kinase 0.0131 0.0483 0.1049
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0065 0.0224 0.0223
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0138 0.0509 0.0509
Echinococcus multilocularis adenosine kinase 0.1149 0.4456 0.4455
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.2569 1 1
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0138 0.0307
Trypanosoma brucei purine nucleoside transporter 0.0446 0.1713 0.3821
Echinococcus multilocularis lamin dm0 0.0028 0.0079 0.0078
Schistosoma mansoni DNA helicase recq5 0.0009 0.0007 0.0014
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0446 0.1713 0.1713
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0048
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0076 0.0069
Brugia malayi Pyruvate kinase, muscle isozyme 0.0034 0.0105 0.0105
Brugia malayi acetyltransferase, GNAT family protein 0.015 0.0559 0.0559
Giardia lamblia Ribokinase 0.0131 0.0483 0.0476
Trypanosoma brucei adenosine transporter 2 0.0446 0.1713 0.3821
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0015 0.003
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.0131 0.0483 1
Entamoeba histolytica fructokinase, putative 0.0131 0.0483 0.0466
Loa Loa (eye worm) RGS-3 protein 0.002 0.0048 0.0048
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0048 0.0047
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0105 0.0104
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0037 0.0037
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.007 0.014
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0509 0.114
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0057 0.0057
Entamoeba histolytica hypothetical protein 0.0042 0.0138 0.0121
Loa Loa (eye worm) hypothetical protein 0.0152 0.0567 0.0567
Schistosoma mansoni adenosine kinase 0.1149 0.4456 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0034 0.0033
Plasmodium falciparum flap endonuclease 1 0.0027 0.0076 0.5694
Entamoeba histolytica hypothetical protein 0.0042 0.0138 0.0121
Schistosoma mansoni hypothetical protein 0.0011 0.0016 0.0033
Loa Loa (eye worm) hypothetical protein 0.1149 0.4456 0.4456
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0076 0.0131
Echinococcus granulosus lamin dm0 0.0028 0.0079 0.0078
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0034 0.0037
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0048 0.0047
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0004 0.0003
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0009 0.0007 0.0007
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0079 0.0079
Schistosoma mansoni hypothetical protein 0.0017 0.0037 0.0081
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.0405 0.0404
Echinococcus granulosus intermediate filament protein 0.0028 0.0079 0.0078
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0109 0.0108
Loa Loa (eye worm) RecQ helicase 0.0022 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0017 0.0037 0.0037
Trichomonas vaginalis ribokinase, putative 0.0131 0.0483 0.0482
Schistosoma mansoni hypothetical protein 0.0036 0.0113 0.0251
Leishmania major adenosine kinase-like protein 0.0131 0.0483 0.1049
Loa Loa (eye worm) hypothetical protein 0.0039 0.0125 0.0125
Schistosoma mansoni hypothetical protein 0.0021 0.0054 0.0119
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0446 0.1713 0.3821
Trypanosoma cruzi ribokinase, putative 0.0131 0.0483 0.1049
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0047
Trypanosoma brucei adenosine transporter 2, putative 0.0446 0.1713 0.3821
Loa Loa (eye worm) hypothetical protein 0.0053 0.0178 0.0178
Onchocerca volvulus 0.0049 0.0164 0.0085
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0048
Leishmania major hypothetical protein, conserved 0.0016 0.0033 0.0035
Loa Loa (eye worm) hypothetical protein 0.0072 0.0254 0.0254
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0405 0.0388
Echinococcus multilocularis voltage gated potassium channel 0.0011 0.0015 0.0014
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0164 0.0164
Trypanosoma brucei pyruvate kinase 1, putative 0.0034 0.0105 0.0197
Schistosoma mansoni zinc finger protein 0.0016 0.0033 0.0072
Echinococcus granulosus lamin 0.0028 0.0079 0.0078
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0048 0.0106
Schistosoma mansoni regulator of G protein signaling 0.002 0.0048 0.0106
Brugia malayi MH1 domain containing protein 0.0008 0.0004 0.0004
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0178 0.0178
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0048 0.0047
Brugia malayi STAT protein, DNA binding domain containing protein 0.0132 0.0489 0.0489
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0076 0.0075
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0007 0.00000000003593
Trypanosoma brucei adenosine transporter 2, putative 0.0446 0.1713 0.3821
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0048 0.0047
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0034 0.0061
Echinococcus granulosus GPCR family 2 0.0017 0.0037 0.0036
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.0131 0.0483 0.0466
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0446 0.1713 0.3821
Leishmania major tagatose-6-phosphate kinase-like protein 0.0131 0.0483 0.1049
Leishmania major cytochrome p450-like protein 0.0013 0.0021 0.0008
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0004 0.0004
Mycobacterium ulcerans pyruvate kinase 0.0034 0.0105 0.1816
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.2569 1 1
Loa Loa (eye worm) phosphofructokinase 0.0111 0.0405 0.0405
Trypanosoma brucei adenosine kinase, putative 0.1149 0.4456 1
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0405 0.0388
Loa Loa (eye worm) transcription factor SMAD2 0.012 0.0441 0.0441
Echinococcus multilocularis Smad4 0.0008 0.0004 0.0003
Trypanosoma brucei unspecified product 0.0446 0.1713 0.3821
Brugia malayi MH2 domain containing protein 0.012 0.0441 0.0441
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.003 0.003
Leishmania major ribokinase, putative 0.0131 0.0483 0.1049
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.0131 0.0483 0.0482
Loa Loa (eye worm) hypothetical protein 0.0452 0.1737 0.1737
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0034 0.0037
Trichomonas vaginalis ribokinase, putative 0.0131 0.0483 0.0482
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.0405 0.8266
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0037 0.0037
Trypanosoma cruzi nucleobase transporter, putative 0.0446 0.1713 0.3821
Echinococcus multilocularis GPCR, family 2 0.0017 0.0037 0.0036
Brugia malayi Muscleblind-like protein 0.0152 0.0567 0.0567
Trypanosoma brucei ribokinase, putative 0.0131 0.0483 0.1049
Brugia malayi Cytochrome P450 family protein 0.0013 0.0021 0.0021
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0089 0.0184
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0034 0.2236
Schistosoma mansoni hypothetical protein 0.0017 0.0037 0.0081
Schistosoma mansoni ribokinase 0.0131 0.0483 0.1082
Echinococcus granulosus pyruvate kinase 0.0034 0.0105 0.0104
Schistosoma mansoni zinc finger protein 0.0024 0.0064 0.0142
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.004 0.0087
Echinococcus granulosus smad 0.0008 0.0004 0.0003
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.007 0.0117
Trypanosoma cruzi nucleoside transporter 1, putative 0.0446 0.1713 0.3821
Toxoplasma gondii kinase, pfkB family protein 0.0131 0.0483 0.107
Loa Loa (eye worm) hypothetical protein 0.0008 0.0003 0.0003
Trypanosoma cruzi nucleoside transporter 1, putative 0.0446 0.1713 0.3821
Giardia lamblia Hypothetical protein 0.2569 1 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0034 0.0105 0.0105
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0405 0.0404
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0076 0.0131
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0151 0.015
Brugia malayi 6-phosphofructokinase 0.0111 0.0405 0.0405
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0048
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.004 0.0039
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0021 0.0008
Trichomonas vaginalis pyruvate kinase, putative 0.0034 0.0105 0.0104
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0048 0.0106
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0048 0.0047
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.001 0.0012 0.0012
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0047 0.3284
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.0015
Echinococcus granulosus bloom syndrome protein 0.0022 0.0057 0.0056
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0446 0.1713 0.1713
Brugia malayi hypothetical protein 0.0042 0.0138 0.0138
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0089 0.4888
Trypanosoma brucei cytochrome P450, putative 0.0013 0.0021 0.0008
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0178 0.0178
Brugia malayi intermediate filament protein 0.0028 0.0079 0.0079
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0089 0.0088
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0089 0.0082
Brugia malayi Bromodomain containing protein 0.0043 0.0139 0.0139
Schistosoma mansoni flap endonuclease-1 0.0024 0.0066 0.0145
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0151 0.015
Brugia malayi MH2 domain containing protein 0.0008 0.0004 0.0004
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0446 0.1713 0.1713
Loa Loa (eye worm) STAT protein 0.0132 0.0489 0.0489
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0004 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.007 0.0117
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0039 0.0085
Loa Loa (eye worm) hypothetical protein 0.0028 0.0079 0.0079
Brugia malayi hypothetical protein 0.0131 0.0483 0.0483
Trypanosoma cruzi adenosine kinase, putative 0.0131 0.0483 0.1049
Loa Loa (eye worm) hypothetical protein 0.0036 0.0113 0.0113
Echinococcus granulosus voltage gated potassium channel 0.0011 0.0015 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0089 0.0088
Entamoeba histolytica hypothetical protein 0.002 0.0048 0.0031
Loa Loa (eye worm) hypothetical protein 0.0007 0.0001 0.0001
Echinococcus multilocularis lamin 0.0028 0.0079 0.0078
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.0405 0.0873
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0076 0.38
Entamoeba histolytica hypothetical protein 0.002 0.0048 0.0031
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0062 0.0061
Onchocerca volvulus Ribokinase homolog 0.0131 0.0483 0.0407
Schistosoma mansoni lozenge 0.0057 0.0193 0.0432
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0048 0.0048
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0446 0.1713 0.1713
Echinococcus granulosus zinc finger protein 0.0024 0.0064 0.0063
Schistosoma mansoni pyruvate kinase 0.0034 0.0105 0.0233
Brugia malayi hypothetical protein 0.0452 0.1737 0.1737
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0405 0.0873
Trypanosoma cruzi adenosine kinase, putative 0.1149 0.4456 1
Schistosoma mansoni smad 0.0008 0.0004 0.0006
Schistosoma mansoni Smad4 0.0008 0.0004 0.0006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0509 0.0508
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0151 0.0324
Loa Loa (eye worm) hypothetical protein 0.2569 1 1
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0048 0.0048
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.0405 1
Trypanosoma cruzi ISWI complex protein 0.0016 0.0033 0.0035
Loa Loa (eye worm) runx1 0.0057 0.0193 0.0193
Echinococcus granulosus Smad4 0.0008 0.0004 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0047
Plasmodium falciparum pyruvate kinase 2 0.0017 0.004 0.2747
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.0405 0.0388
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.015 0.0559 0.0558
Toxoplasma gondii nucleoside transporter protein 0.0446 0.1713 0.3836
Brugia malayi PXA domain containing protein 0.002 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0241 0.0914 0.0914
Brugia malayi Bromodomain containing protein 0.008 0.0285 0.0285
Echinococcus granulosus pyruvate kinase 0.0034 0.0105 0.0104
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0048 0.0047
Entamoeba histolytica pyruvate kinase, putative 0.0024 0.0065 0.0047
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0034 0.0037
Leishmania major nucleoside transporter 1, putative 0.0446 0.1713 0.3821
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0048 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0047
Trypanosoma cruzi nucleobase transporter, putative 0.0446 0.1713 0.3821
Toxoplasma gondii pyruvate kinase PyK1 0.0034 0.0105 0.022
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0048
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0048 0.0047
Loa Loa (eye worm) pyruvate kinase-PB 0.0024 0.0065 0.0065
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0024 0.0023
Echinococcus granulosus equilibrative nucleoside transporter 3 0.2569 1 1
Plasmodium falciparum pyruvate kinase 0.0034 0.0105 0.8112
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.007 0.5177
Trypanosoma brucei adenosine transporter 2, putative 0.0446 0.1713 0.3821
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0509 0.0508
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0533 0.0532
Schistosoma mansoni intermediate filament proteins 0.0028 0.0079 0.0176
Leishmania major nucleobase transporter 0.0446 0.1713 0.3821
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0567 0.0566
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.004 0.0087
Brugia malayi Flap endonuclease-1 0.0027 0.0076 0.0076
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0048 0.0047
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2569 1 1
Schistosoma mansoni regulator of G protein signaling 0.002 0.0048 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0131 0.0483 0.0482
Echinococcus granulosus pyruvate kinase 0.0017 0.004 0.0039
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.007 0.0117
Entamoeba histolytica kinase, PfkB family 0.0131 0.0483 0.0466
Leishmania major pyruvate kinase 0.0034 0.0105 0.0197
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0009 0.0007 0.0006
Brugia malayi Ribokinase 0.0131 0.0483 0.0483
Entamoeba histolytica hypothetical protein 0.0042 0.0138 0.0121
Loa Loa (eye worm) hypothetical protein 0.2569 1 1
Echinococcus granulosus muscleblind protein 0.0152 0.0567 0.0566
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0042 0.0138 0.0307
Trypanosoma brucei ISWI complex protein 0.0016 0.0033 0.0035
Echinococcus multilocularis ribokinase 0.0131 0.0483 0.0482
Schistosoma mansoni bromodomain containing protein 0.0068 0.0238 0.0532
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0011 0.0015 0.0015
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0119 0.0118
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0446 0.1713 0.3821
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0119 0.0119
Echinococcus multilocularis pyruvate kinase 0.0017 0.004 0.0039
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0089 0.6793
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0034 0.0033
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0405 0.0907
Brugia malayi Smad1 0.0008 0.0004 0.0004
Echinococcus multilocularis zinc finger protein 0.0024 0.0064 0.0063
Loa Loa (eye worm) hypothetical protein 0.0152 0.0567 0.0567
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2569 1 1
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.0914 0.0913
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0105 0.0026
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0007 0.0007
Trichomonas vaginalis ribokinase, putative 0.0131 0.0483 0.0482
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.0131 0.0483 0.0466
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.004 0.0087
Schistosoma mansoni hypothetical protein 0.0017 0.0037 0.0081
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0105 0.0026
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0138 0.0509 0.0508
Trypanosoma brucei unspecified product 0.0446 0.1713 0.3821
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.2569 1 1
Schistosoma mansoni pyruvate kinase 0.0017 0.004 0.0088
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0089 0.0088
Loa Loa (eye worm) hypothetical protein 0.0131 0.0483 0.0483
Brugia malayi Adenosine kinase-like 0.1149 0.4456 0.4456
Echinococcus granulosus axis inhibition protein axin 0.002 0.0048 0.0047
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0034 0.0074
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0034 0.0034
Schistosoma mansoni regulator of G protein signaling 0.002 0.0048 0.0106
Mycobacterium leprae Probable adenosine kinase adk 0.0131 0.0483 1
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0057 0.0056
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0034 0.0033
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0048 0.0047
Echinococcus granulosus equilibrative nucleoside transporter 0.2569 1 1
Loa Loa (eye worm) hypothetical protein 0.0452 0.1737 0.1737
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0037 0.0037
Echinococcus multilocularis expressed protein 0.0381 0.1459 0.1458
Entamoeba histolytica nucleoside transporter, putative 0.0446 0.1713 0.1699
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0076 0.0131
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0405 0.0404
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0034 0.0105 0.1579
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0048 0.0048
Brugia malayi hypothetical protein 0.0025 0.007 0.007
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.0405 0.0873
Leishmania major nucleobase transporter 0.0446 0.1713 0.3821
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0048 0.0106
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0004 0.0006
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0011 0.0015 0.0014
Brugia malayi hypothetical protein 0.002 0.0048 0.0048
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0025 0.007 0.007
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0048 0.0048
Trypanosoma brucei adenosine kinase, putative 0.1149 0.4456 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0057 0.0056
Brugia malayi MH1 domain containing protein 0.0008 0.0004 0.0004
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0016 0.0015
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0048 0.0048
Entamoeba histolytica ribokinase, putative 0.0131 0.0483 0.0466
Giardia lamblia Pyruvate kinase 0.0017 0.004 0.0033
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0017 0.0016
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0006
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0016 0.0015
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0048 0.0106
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0048 0.0047
Onchocerca volvulus 0.0452 0.1737 0.1671
Loa Loa (eye worm) cytochrome P450 family protein 0.0013 0.0021 0.0021
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0076 0.0058
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.004 0.0074
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0007 0.0001 0.0001
Brugia malayi PHD-finger family protein 0.0029 0.0085 0.0085
Loa Loa (eye worm) CYP4Cod1 0.0013 0.0021 0.0021
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0089 0.0184
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0048 0.0047
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0405 0.0405
Brugia malayi Cytochrome P450 family protein 0.0013 0.0021 0.0021
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0151 0.0324
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0034 0.0033
Loa Loa (eye worm) hypothetical protein 0.0033 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.0013 0.0024 0.0024
Plasmodium vivax pyruvate kinase, putative 0.0034 0.0105 0.6194
Mycobacterium ulcerans fructokinase, PfkB 0.0131 0.0483 1
Loa Loa (eye worm) hypothetical protein 0.2569 1 1
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0048 0.0106
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Brugia malayi isocitrate dehydrogenase 0.0016 0.0034 0.0034
Trypanosoma brucei adenosine transporter 2, putative 0.0446 0.1713 0.3821
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0138 0.0509 0.0509
Toxoplasma gondii kinase, pfkB family protein 0.1149 0.4456 1
Echinococcus granulosus pyruvate kinase 0.0017 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0022
Trypanosoma brucei ribokinase, putative 0.0131 0.0483 0.1049
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.0405 0.0907
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0178 0.0178
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0405 0.0404
Schistosoma mansoni DNA helicase recq1 0.0009 0.0007 0.0014
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Echinococcus multilocularis Protein lozenge 0.0057 0.0193 0.0192
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0048 0.0048
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0446 0.1713 0.3821
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0004 0.0003
Echinococcus multilocularis pyruvate kinase 0.0027 0.0077 0.0076
Entamoeba histolytica hypothetical protein 0.002 0.0048 0.0031
Leishmania major pyruvate kinase 0.0034 0.0105 0.0197
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.0405 0.0404
Trypanosoma brucei adenosine transporter 2 0.0446 0.1713 0.3821
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0138 0.0137
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.004 0.0087
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2569 1 1
Schistosoma mansoni pyruvate kinase 0.0034 0.0105 0.0233
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0089 0.0088
Echinococcus multilocularis pyruvate kinase 0.0017 0.004 0.0039
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.0405 0.8315
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0011 0.0015 0.0014
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.0131 0.0483 0.0482
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0034 0.0034
Echinococcus multilocularis pyruvate kinase 0.0017 0.004 0.0039
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0089 0.0184
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0089 0.0088
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0079 0.0079
Brugia malayi hypothetical protein 0.2569 1 1
Schistosoma mansoni axis inhibition protein axin 0.002 0.0048 0.0106
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0009 0.0007 0.0006
Mycobacterium ulcerans carbohydrate kinase CbhK 0.0131 0.0483 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0006
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0128 0.0121
Leishmania major hypothetical protein, conserved 0.0025 0.007 0.0117
Toxoplasma gondii nucleoside transporter protein 0.0446 0.1713 0.3836
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0105 0.0105
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.0405 0.7941
Echinococcus multilocularis smad 0.0008 0.0004 0.0003
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0151 1
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0105 0.0105
Trypanosoma cruzi adenosine kinase, putative 0.1149 0.4456 1
Trypanosoma brucei adenosine transporter, putative 0.0446 0.1713 0.3821
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0027 0.0077 0.0077
Schistosoma mansoni hypothetical protein 0.0049 0.0164 0.0366
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0048 0.0048
Loa Loa (eye worm) MH2 domain-containing protein 0.012 0.0441 0.0441
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0151 0.015
Giardia lamblia Pyruvate kinase 0.0034 0.0105 0.0098
Trypanosoma cruzi ISWI complex protein 0.0016 0.0033 0.0035
Schistosoma mansoni hypothetical protein 0.0016 0.0033 0.0072
Schistosoma mansoni lamin 0.0028 0.0079 0.0176
Schistosoma mansoni smad1 5 8 and 0.0008 0.0004 0.0006
Schistosoma mansoni regulator of G protein signaling 0.002 0.0048 0.0106
Trypanosoma cruzi adenosine kinase, putative 0.0131 0.0483 0.1049
Echinococcus multilocularis pyruvate kinase 0.0034 0.0105 0.0104
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0446 0.1713 0.1713
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.004 0.0039
Echinococcus granulosus pyruvate kinase 0.0017 0.004 0.0039
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0128 1
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0128 0.011
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0034 0.0037
Leishmania major adenosine kinase-like protein 0.0131 0.0483 0.1049
Trypanosoma cruzi cytochrome P450, putative 0.0013 0.0021 0.0008
Echinococcus multilocularis geminin 0.0504 0.1939 0.1939
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0828 0.3203 0.3202
Loa Loa (eye worm) hypothetical protein 0.0009 0.0007 0.0007
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.2569 1 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0089 0.6793
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0119 0.0118
Echinococcus granulosus geminin 0.0504 0.1939 0.1939
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0034 0.0033
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0034 0.0033
Brugia malayi PXA domain containing protein 0.002 0.0048 0.0048
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0115 0.0114
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0132 0.0295
Leishmania major nucleoside transporter 1, putative 0.0446 0.1713 0.3821
Trypanosoma brucei nucleoside transporter 1, putative 0.0446 0.1713 0.3821
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0138 0.0509 0.114
Brugia malayi hypothetical protein 0.0016 0.0035 0.0035
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0057 0.0056
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0048 0.0047
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.004 0.0039
Loa Loa (eye worm) hypothetical protein 0.0047 0.0156 0.0156
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0037 0.0036
Echinococcus granulosus ribokinase 0.0131 0.0483 0.0482
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.2569 1 1
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.0405 0.0404
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0034 0.0037
Leishmania major adenosine kinase, putative 0.1149 0.4456 1
Trypanosoma brucei pyruvate kinase 1 0.0034 0.0105 0.0197
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0062 0.0136
Trypanosoma cruzi nucleoside transporter-like, putative 0.0446 0.1713 0.3821
Entamoeba histolytica hypothetical protein 0.0042 0.0138 0.0121
Trypanosoma cruzi nucleoside transporter 1, putative 0.0446 0.1713 0.3821
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0048 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0047
Echinococcus granulosus axis inhibition protein axin 0.002 0.0048 0.0047
Trypanosoma brucei adenosine transporter 2, putative 0.0446 0.1713 0.3821
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0034 0.0375
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0048 0.0047
Brugia malayi phosphofructokinase 0.0111 0.0405 0.0405
Onchocerca volvulus 0.0131 0.0483 0.0407
Schistosoma mansoni hypothetical protein 0.0504 0.1939 0.4351
Loa Loa (eye worm) hypothetical protein 0.0017 0.004 0.004
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0105 0.0197
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.0405 0.0405
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0446 0.1713 0.3821
Schistosoma mansoni voltage-gated potassium channel 0.0041 0.0132 0.0295
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0089 0.0088
Loa Loa (eye worm) pyruvate kinase 0.0034 0.0105 0.0105
Entamoeba histolytica nucleoside transporter, putative 0.0446 0.1713 0.1699
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0048 0.0048
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0035 0.0109 0.0108
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0048 0.0047
Echinococcus granulosus adenosine kinase 0.1149 0.4456 0.4455
Echinococcus granulosus expressed protein 0.0381 0.1459 0.1458
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0089 0.4888
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0015 0.0029 0.0049
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.0914 0.0913
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0089 0.0072
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.002 0.0048 0.0048
Schistosoma mansoni protein kinase 0.0446 0.1713 0.3844
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0115 0.0114
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0048 0.0047
Loa Loa (eye worm) Smad1 0.0008 0.0004 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.007 0.5177
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0047
Loa Loa (eye worm) hypothetical protein 0.0045 0.0148 0.0148
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0048 0.0106
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0076 0.0076
Onchocerca volvulus Pyruvate kinase homolog 0.0034 0.0105 0.0026
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.003 0.003
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0048 0.0047
Trypanosoma brucei nucleoside transporter 1, putative 0.0446 0.1713 0.3821
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0024 0.0065 0.0065
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0009 0.0007 0.0006
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0048 0.0047
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.2123 0.8259 0.8258
Schistosoma mansoni voltage-gated potassium channel 0.0011 0.0015 0.003
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0009 0.0007 0.0007
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0131 0.0483 0.0483
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0113 0.0113
Brugia malayi 6-phosphofructokinase 0.0111 0.0405 0.0405
Trypanosoma cruzi pyruvate kinase 2, putative 0.0034 0.0105 0.0197
Schistosoma mansoni hypothetical protein 0.0017 0.0037 0.0081
Echinococcus multilocularis musashi 0.0028 0.0079 0.0078
Trypanosoma brucei adenosine transporter, putative 0.0446 0.1713 0.3821
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0138 0.0509 0.0508
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0076 0.0154
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0446 0.1713 0.3821
Brugia malayi hypothetical protein 0.0241 0.0914 0.0914
Schistosoma mansoni lamin 0.0028 0.0079 0.0176
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0034 0.0061
Entamoeba histolytica nucleoside transporter, putative 0.2569 1 1
Schistosoma mansoni equilibrative nucleoside transporter 0.0446 0.1713 0.3844
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0138 0.0137
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0054 0.0054
Mycobacterium tuberculosis Ribokinase RbsK 0.0131 0.0483 1
Brugia malayi hypothetical protein 0.0446 0.1713 0.1713
Echinococcus multilocularis muscleblind protein 0.0152 0.0567 0.0566
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.004 0.0039
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0065 0.0224 0.0223
Echinococcus multilocularis pyruvate kinase 0.0034 0.0105 0.0104
Schistosoma mansoni adenosine kinase 0.1149 0.4456 1
Echinococcus granulosus flap endonuclease 1 0.0027 0.0076 0.0075
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0089 0.0088
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0076 0.0075
Toxoplasma gondii nucleoside transporter protein 0.0446 0.1713 0.3836
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0062 0.0061

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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