Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | PAB1-binding protein , putative | 0.0053 | 0.1585 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0053 | 0.1585 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.2283 | 0.7824 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0053 | 0.1585 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2918 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0066 | 0.2283 | 0.182 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.2283 | 0.083 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.2283 | 0.3552 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0066 | 0.2283 | 0.083 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0066 | 0.2283 | 0.7824 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.2283 | 0.7824 |
Brugia malayi | hypothetical protein | 0.0053 | 0.1585 | 0.1079 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0066 | 0.2283 | 0.182 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0066 | 0.2283 | 0.7824 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0053 | 0.1585 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.2283 | 0.3552 |
Brugia malayi | hypothetical protein | 0.0078 | 0.2918 | 0.2493 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2918 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0078 | 0.2918 | 0.4539 |
Echinococcus multilocularis | GPCR, family 2 | 0.0066 | 0.2283 | 0.7824 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.2283 | 0.3552 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0053 | 0.1585 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2918 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0053 | 0.1585 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0078 | 0.2918 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0209 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.2283 | 0.3552 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0053 | 0.1585 | 0.5 |
Echinococcus granulosus | GPCR family 2 | 0.0066 | 0.2283 | 0.7824 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 0.6428 | 0.5756 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0209 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0053 | 0.1585 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.6428 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0143 | 0.6428 | 0.6214 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0078 | 0.2918 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.2918 | 0.4539 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0078 | 0.2918 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.