Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0033 | 0.0266 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0033 | 0.0266 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0033 | 0.0266 | 0.5 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0033 | 0.0266 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0021 | 0 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0448 | 0.9749 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0438 | 0.9524 | 0.977 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0033 | 0.0266 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0021 | 0 | 0.5 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0033 | 0.0266 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.0448 | 0.9749 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0021 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase | 0.0033 | 0.0266 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0021 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0033 | 0.0266 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0021 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0033 | 0.0266 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0033 | 0.0266 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0021 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.