Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0478 | 0.0597 | 0.0597 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.3979 | 0.8872 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.0064 | 0.0068 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0478 | 0.0597 | 0.063 |
Brugia malayi | nuclear receptor NHR-88 | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0478 | 0.0597 | 0.0635 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.4232 | 0.9469 | 1 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0478 | 0.0597 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0253 | 0.0064 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0478 | 0.0597 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0478 | 0.0597 | 0.063 |
Schistosoma mansoni | nuclear hormone receptor | 0.0478 | 0.0597 | 0.063 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0253 | 0.0064 | 0.0068 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0478 | 0.0597 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.0064 | 0.0068 |
Brugia malayi | ecdysteroid receptor | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | nuclear receptor RXR | 0.0253 | 0.0064 | 0.0068 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0478 | 0.0597 | 0.0673 |
Brugia malayi | nuclear hormone receptor | 0.4204 | 0.9403 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0478 | 0.0597 | 0.0635 |
Onchocerca volvulus | 0.0478 | 0.0597 | 0.0597 | |
Schistosoma mansoni | thyroid hormone receptor | 0.0478 | 0.0597 | 0.063 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0253 | 0.0064 | 0.0067 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | hypothetical protein | 0.0253 | 0.0064 | 0.0068 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0478 | 0.0597 | 0.0635 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0478 | 0.0597 | 0.0673 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0478 | 0.0597 | 0.0673 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.0064 | 0.0068 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0478 | 0.0597 | 0.0635 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0478 | 0.0597 | 0.0673 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0478 | 0.0597 | 0.0673 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0478 | 0.0597 | 0.063 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0253 | 0.0064 | 0.0072 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0478 | 0.0597 | 0.0635 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus granulosus | FTZ F1 alpha | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0478 | 0.0597 | 0.0635 |
Schistosoma mansoni | coup transcription factor | 0.0478 | 0.0597 | 0.063 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0478 | 0.0597 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.3978 | 0.887 | 0.9433 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.4204 | 0.9403 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0253 | 0.0064 | 0.0067 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0478 | 0.0597 | 0.0673 |
Schistosoma mansoni | thyroid hormone receptor | 0.0478 | 0.0597 | 0.063 |
Brugia malayi | nuclear hormone receptor | 0.0478 | 0.0597 | 0.0635 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0478 | 0.0597 | 0.0635 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0253 | 0.0064 | 0.0067 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.0064 | 0.0068 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0478 | 0.0597 | 0.063 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0478 | 0.0597 | 0.063 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0478 | 0.0597 | 0.063 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0478 | 0.0597 | 0.0635 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0478 | 0.0597 | 0.0635 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0478 | 0.0597 | 0.0597 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0478 | 0.0597 | 0.063 |
Brugia malayi | steroid hormone receptor | 0.0478 | 0.0597 | 0.0635 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.4232 | 0.9469 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0478 | 0.0597 | 0.063 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.0064 | 0.0068 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0478 | 0.0597 | 0.0635 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0478 | 0.0597 | 0.0673 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0478 | 0.0597 | 0.063 |
Brugia malayi | hypothetical protein | 0.0253 | 0.0064 | 0.0068 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0253 | 0.0064 | 0.0068 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.