Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0314 | 0.0443 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0025 | 0.0318 | 0.0259 |
Trichomonas vaginalis | glutaminase, putative | 0.0265 | 0.7099 | 0.7076 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0109 | 0.2689 | 0.2685 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.1122 | 0.1755 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0109 | 0.2689 | 0.2638 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0025 | 0.0318 | 0.0312 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0771 | 0.1173 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.0962 | 0.1356 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.025 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0025 | 0.0318 | 0.2682 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0025 | 0.0318 | 0.0421 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0446 | 0.0633 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0023 | 0.0257 | 0.0252 |
Schistosoma mansoni | transcription factor btf3 | 0.0035 | 0.0611 | 0.0778 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0446 | 0.0542 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0314 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.061 | 0.0859 |
Brugia malayi | beta-NAC-like protein | 0.0035 | 0.0611 | 0.0778 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.002 | 0.0168 | 0.0099 |
Onchocerca volvulus | 0.0047 | 0.0935 | 0.8027 | |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0368 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0093 | 0.0041 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0176 | 0.0187 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0026 | 0.0345 | 0.0278 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0025 | 0.0318 | 0.2682 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.061 | 0.0604 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.0962 | 0.1491 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0025 | 0.0318 | 0.0238 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0342 | 0.0461 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0036 | 0.062 | 0.0923 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.061 | 0.0532 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0176 | 0.016 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0356 | 0.0277 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.062 | 0.0791 |
Onchocerca volvulus | 0.0035 | 0.061 | 0.4584 | |
Echinococcus granulosus | lamin | 0.0053 | 0.1122 | 0.1755 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.061 | 0.0544 |
Onchocerca volvulus | 0.0053 | 0.1122 | 1 | |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.0962 | 0.1356 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.061 | 0.0532 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0368 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.1122 | 0.1503 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0026 | 0.0345 | 0.0278 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0935 | 0.1238 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0229 | 0.6089 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0017 | 0.0082 | 0.0029 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.0962 | 0.1277 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0024 | 0.0303 | 0.0297 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0446 | 0.0542 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.061 | 0.0604 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0356 | 0.0415 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0096 | 0.2336 | 0.3771 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.1122 | 0.1755 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.0025 | 0.0318 | 0.025 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.061 | 0.0859 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.025 |
Brugia malayi | hypothetical protein | 0.002 | 0.0176 | 0.016 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0024 | 0.0303 | 0.0297 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0026 | 0.0345 | 0.034 |
Brugia malayi | hypothetical protein | 0.002 | 0.0176 | 0.016 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.3744 | 0.6107 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0017 | 0.0082 | 0.0012 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.1036 | 0.1381 |
Echinococcus multilocularis | RUN | 0.002 | 0.0176 | 0.0187 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0119 | 0.2976 | 0.4834 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0024 | 0.0303 | 0.0235 |
Mycobacterium ulcerans | polyketide synthase | 0.0024 | 0.0303 | 0.0235 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0036 | 0.0643 | 0.0577 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.4298 | 0.6019 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0025 | 0.0318 | 0.0238 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0035 | 0.0611 | 0.6012 |
Loa Loa (eye worm) | glutaminase 2 | 0.0265 | 0.7099 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0356 | 0.0297 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.061 | 0.0906 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.002 | 0.0176 | 0.0187 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0017 | 0.0104 | 0.0044 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0024 | 0.0303 | 0.0235 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0023 | 0.0257 | 0.0363 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.1036 | 0.1381 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.0962 | 0.0888 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.002 | 0.0176 | 0.0187 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.025 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0036 | 0.062 | 0.0874 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Echinococcus granulosus | transcription factor btf3 | 0.0035 | 0.0611 | 0.0908 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.061 | 0.0604 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1122 | 0.158 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0026 | 0.0345 | 0.0278 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0064 | 0.009 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.0176 | 0.0096 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.061 | 0.0776 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.061 | 0.0859 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.0422 | 0.0594 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.002 | 0.0176 | 0.0187 |
Loa Loa (eye worm) | oxidoreductase | 0.0025 | 0.0318 | 0.0448 |
Loa Loa (eye worm) | ICD-1 protein | 0.0035 | 0.0611 | 0.0861 |
Schistosoma mansoni | lipoxygenase | 0.0119 | 0.2976 | 0.414 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0446 | 0.0628 |
Onchocerca volvulus | 0.0025 | 0.0318 | 0.1495 | |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0176 | 0.016 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0024 | 0.0303 | 0.0339 |
Leishmania major | basic transcription factor 3a, putative | 0.0035 | 0.0611 | 0.6012 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0119 | 0.2976 | 0.4834 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0017 | 0.0082 | 0.0076 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.061 | 0.0532 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0096 | 0.2336 | 0.3771 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.061 | 0.0604 |
Mycobacterium ulcerans | thioesterase TesA | 0.002 | 0.0188 | 0.0119 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0024 | 0.0303 | 0.0235 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0017 | 0.0082 | 0.0021 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.061 | 0.0544 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0356 | 0.0277 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.1122 | 0.1503 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0017 | 0.0109 | 0.0103 |
Toxoplasma gondii | thioredoxin reductase | 0.0048 | 0.0962 | 0.0907 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0025 | 0.0318 | 0.0312 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.3744 | 0.6107 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0026 | 0.0345 | 0.0286 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0017 | 0.0082 | 0.0012 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0036 | 0.0643 | 0.0577 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium ulcerans | thioesterase | 0.002 | 0.0188 | 0.0119 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.0422 | 0.0508 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0064 | 0.009 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0446 | 0.0633 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0121 | 0.3032 | 0.2983 |
Leishmania major | oxidoreductase-like protein | 0.0025 | 0.0318 | 0.2682 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0017 | 0.0082 | 0.0029 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0025 | 0.0318 | 0.0312 |
Trypanosoma brucei | oxidoreductase-like protein | 0.0025 | 0.0318 | 0.2682 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.061 | 0.5996 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.1122 | 0.1503 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.061 | 0.0859 |
Onchocerca volvulus | 0.0035 | 0.061 | 0.4584 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0356 | 0.0501 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0229 | 0.6089 | 1 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0368 | 1 | 1 |
Schistosoma mansoni | glutaminase | 0.0265 | 0.7099 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.061 | 0.0859 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0109 | 0.2689 | 0.2685 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0342 | 0.0481 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0356 | 0.0277 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0024 | 0.0303 | 0.0297 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0017 | 0.0082 | 0.0021 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0036 | 0.0643 | 0.0638 |
Onchocerca volvulus | 0.0053 | 0.1122 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.1094 | 0.1541 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.061 | 0.0859 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0025 | 0.0318 | 0.0238 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0024 | 0.0303 | 0.0235 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0109 | 0.2689 | 0.2685 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.6089 | 0.8577 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.061 | 0.0544 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0025 | 0.0318 | 0.0448 |
Onchocerca volvulus | 0.0025 | 0.0318 | 0.1495 | |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.0962 | 1 |
Onchocerca volvulus | 0.0023 | 0.0257 | 0.0856 | |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0026 | 0.0345 | 0.034 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0368 | 1 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.0962 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0109 | 0.2689 | 0.2685 |
Schistosoma mansoni | lamin | 0.0053 | 0.1122 | 0.1503 |
Onchocerca volvulus | 0.0042 | 0.0812 | 0.6726 | |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.2682 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.2682 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.061 | 0.5996 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0121 | 0.3032 | 0.3028 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.002 | 0.0168 | 0.0099 |
Schistosoma mansoni | lipoxygenase | 0.0083 | 0.1965 | 0.2702 |
Schistosoma mansoni | rab6-interacting | 0.002 | 0.0176 | 0.016 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.0312 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.061 | 0.0532 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0025 | 0.0318 | 0.0259 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.061 | 0.0859 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0176 | 0.0187 |
Echinococcus multilocularis | lamin | 0.0053 | 0.1122 | 0.1755 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0586 | 0.0742 |
Leishmania major | trypanothione reductase | 0.0048 | 0.0962 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.061 | 0.0776 |
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.0176 | 0.0096 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0036 | 0.062 | 0.0791 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.0962 | 0.0888 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.061 | 0.0776 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0356 | 0.3115 |
Leishmania major | pteridine reductase 1 | 0.0025 | 0.0318 | 0.2682 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.0312 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0109 | 0.2689 | 0.2685 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.061 | 0.0604 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.3018 | 0.4251 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0025 | 0.0318 | 0.0238 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0024 | 0.0303 | 0.0235 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0044 | 0.0855 | 0.7178 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0026 | 0.0345 | 0.0278 |
Brugia malayi | Doublecortin family protein | 0.002 | 0.0176 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.061 | 0.0859 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.025 |
Brugia malayi | jmjC domain containing protein | 0.0096 | 0.2336 | 0.323 |
Toxoplasma gondii | NAC domain-containing protein | 0.0035 | 0.0611 | 0.0554 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.1122 | 0.1755 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.0025 | 0.0318 | 0.0259 |
Echinococcus multilocularis | geminin | 0.0166 | 0.4298 | 0.7028 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0368 | 1 | 1 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0611 | 0.6012 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0356 | 0.3115 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0935 | 0.1238 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0025 | 0.0318 | 0.0361 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0025 | 0.0318 | 0.025 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.061 | 0.0776 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0611 | 1 |
Brugia malayi | hypothetical protein | 0.0229 | 0.6089 | 0.8564 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0446 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.077 | 0.1085 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0342 | 0.0461 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.133 | 0.1874 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0356 | 0.3115 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0025 | 0.0318 | 0.0312 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0017 | 0.0082 | 0.0012 |
Mycobacterium tuberculosis | Probable reductase | 0.0109 | 0.2689 | 0.2685 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.061 | 0.0532 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.061 | 0.5996 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.002 | 0.0177 | 0.0172 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.3744 | 0.6107 |
Schistosoma mansoni | dihydropteridine reductase | 0.0025 | 0.0318 | 0.0361 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0082 | 0.0025 |
Mycobacterium ulcerans | polyketide synthase | 0.0026 | 0.0345 | 0.0278 |
Echinococcus multilocularis | musashi | 0.0053 | 0.1122 | 0.1755 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.1036 | 0.1459 |
Brugia malayi | glutaminase DH11.1 | 0.0265 | 0.7099 | 1 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0446 | 0.0633 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.002 | 0.0188 | 0.0119 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0025 | 0.0318 | 0.2682 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.0962 | 0.0888 |
Echinococcus multilocularis | transcription factor btf3 | 0.0035 | 0.0611 | 0.0908 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.061 | 0.0604 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.3018 | 0.4198 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.061 | 0.0552 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.0025 | 0.0318 | 0.2682 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0257 | 0.0275 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0446 | 1 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0025 | 0.0318 | 0.2682 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.3744 | 0.5273 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0446 | 0.2847 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0611 | 0.0534 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1039 | 0.1464 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0024 | 0.0303 | 0.0235 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.1122 | 0.158 |
Trypanosoma brucei | pteridine reductase 1 | 0.0025 | 0.0318 | 0.2682 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0611 | 0.0534 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0035 | 0.0611 | 0.0534 |
Loa Loa (eye worm) | fatty acid synthase | 0.0024 | 0.0293 | 0.0413 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0026 | 0.0345 | 0.034 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.0176 | 0.0249 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0121 | 0.3032 | 0.3028 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.061 | 0.0604 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.061 | 0.5996 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0036 | 0.062 | 0.0923 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.4298 | 0.6019 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0446 | 0.0367 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0024 | 0.0281 | 0.0276 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0025 | 0.0318 | 0.0361 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.002 | 0.0168 | 0.0099 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0356 | 0.3115 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.061 | 0.0906 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0025 | 0.0318 | 0.0312 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0368 | 1 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.0312 |
Echinococcus granulosus | RUN | 0.002 | 0.0176 | 0.0187 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0225 | 0.5973 | 0.5971 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0035 | 0.0611 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0025 | 0.0318 | 0.0361 |
Schistosoma mansoni | polycystin 1-related | 0.002 | 0.0176 | 0.016 |
Brugia malayi | jmjC domain containing protein | 0.0036 | 0.062 | 0.0791 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0446 | 0.0387 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0025 | 0.0318 | 0.025 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0025 | 0.0318 | 0.0421 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.061 | 0.0604 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0446 | 0.0387 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.002 | 0.0188 | 0.0182 |
Mycobacterium ulcerans | glutaminase | 0.0265 | 0.7099 | 0.7079 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.002 | 0.0176 | 0.0187 |
Schistosoma mansoni | jumonji domain containing protein | 0.0077 | 0.1777 | 0.2435 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0026 | 0.0345 | 0.0278 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1036 | 0.1459 |
Trichomonas vaginalis | hypothetical protein | 0.0368 | 1 | 1 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0025 | 0.0318 | 0.0312 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.061 | 0.0604 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0446 | 0.0542 |
Mycobacterium ulcerans | oxidoreductase | 0.0025 | 0.0318 | 0.025 |
Echinococcus granulosus | geminin | 0.0166 | 0.4298 | 0.7028 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.061 | 0.0544 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.3744 | 0.523 |
Loa Loa (eye worm) | glutaminase | 0.0265 | 0.7099 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.061 | 0.0544 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0446 | 0.0367 |
Brugia malayi | glutathione reductase | 0.0048 | 0.0962 | 0.1277 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.061 | 0.0544 |
Brugia malayi | beta-lactamase | 0.0035 | 0.061 | 0.0776 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Schistosoma mansoni | loxhd1 | 0.002 | 0.0176 | 0.016 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0771 | 0.1173 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0935 | 0.1238 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.061 | 0.0532 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Schistosoma mansoni | lamin | 0.0053 | 0.1122 | 0.1503 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0318 | 0.0448 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.0962 | 0.0888 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.0962 | 0.1491 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0035 | 0.0611 | 0.0534 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0025 | 0.0318 | 0.0448 |
Onchocerca volvulus | 0.0035 | 0.061 | 0.4584 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.061 | 0.0776 |
Treponema pallidum | NADH oxidase | 0.0017 | 0.0082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.3744 | 0.5273 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0024 | 0.0281 | 0.0276 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0036 | 0.0643 | 0.0638 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0025 | 0.0318 | 0.025 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.3018 | 0.4251 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0121 | 0.3032 | 0.3028 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.061 | 0.0532 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.0025 | 0.0318 | 0.025 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0082 | 0.0025 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0176 | 0.0249 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.0962 | 0.0957 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0046 | 0.0919 | 0.1215 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0176 | 0.0249 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.061 | 0.0604 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.061 | 0.0544 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0368 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0586 | 0.0742 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.1122 | 0.158 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0035 | 0.0611 | 0.0534 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0446 | 0.0542 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0586 | 0.0825 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.0025 | 0.0318 | 0.025 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0446 | 0.0633 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0035 | 0.0611 | 0.6012 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.