Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | phosphofructokinase PFKII | 0.0035 | 0.0756 | 1 |
Brugia malayi | TAR-binding protein | 0.0068 | 0.4034 | 0.4034 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0128 | 1 | 0.5 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0035 | 0.0756 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0128 | 1 | 1 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0128 | 1 | 0.5 |
Brugia malayi | 6-phosphofructokinase | 0.0128 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0068 | 0.4034 | 0.4034 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0128 | 1 | 0.5 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0128 | 1 | 1 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0035 | 0.0756 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0128 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0068 | 0.4034 | 0.4034 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0128 | 1 | 1 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0035 | 0.0756 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0068 | 0.4034 | 0.4034 |
Loa Loa (eye worm) | phosphofructokinase | 0.0128 | 1 | 1 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0035 | 0.0756 | 0.5 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0035 | 0.0756 | 1 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0128 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 1 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0035 | 0.0756 | 1 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0128 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0128 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0128 | 1 | 1 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0035 | 0.0756 | 1 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0128 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0128 | 1 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0035 | 0.0756 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 1 | 1 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0128 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0068 | 0.4034 | 0.4034 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0128 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0068 | 0.4034 | 0.4034 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0128 | 1 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0128 | 1 | 1 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0035 | 0.0756 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0128 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.