Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 1 | 1 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 1 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 1 | 1 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.1835 | 0.1835 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0113 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.4911 | 0.4587 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0031 | 0.1098 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2109 | 0.2014 |
Loa Loa (eye worm) | phosphofructokinase | 0.0113 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.2936 | 0.2936 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4911 | 0.4911 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0113 | 1 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.4904 | 0.4904 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0113 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.2936 | 0.2936 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4911 | 0.4911 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0113 | 1 | 0.5 |
Brugia malayi | 6-phosphofructokinase | 0.0113 | 1 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0031 | 0.1098 | 0.5 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0113 | 1 | 0.5 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0031 | 0.1098 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0333 | 0.0333 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0333 | 0.0333 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.6219 | 0.5978 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.4911 | 0.485 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.1835 | 0.1835 |
Brugia malayi | RNA binding protein | 0.0066 | 0.4911 | 0.4587 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.2101 | 0.1598 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.2936 | 0.2851 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0031 | 0.1098 | 0.5 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 1 | 1 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0031 | 0.1098 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.4502 | 0.4502 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.2374 | 0.2283 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4911 | 0.4911 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0113 | 1 | 0.5 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0113 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.2936 | 0.2936 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0031 | 0.1098 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4911 | 0.4911 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.2936 | 0.2486 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0113 | 1 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0333 | 0.0333 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.4911 | 0.4911 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0113 | 1 | 1 |
Brugia malayi | 6-phosphofructokinase | 0.0113 | 1 | 1 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0113 | 1 | 0.5 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0031 | 0.1098 | 0.5 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0031 | 0.1098 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.4911 | 0.4911 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.4502 | 0.4502 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0113 | 1 | 0.5 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0031 | 0.1098 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.4911 | 0.4911 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2589 | 0.25 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.4911 | 0.485 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0031 | 0.1098 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0119 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.5739 | 0.5688 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.2936 | 0.2936 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.2936 | 0.2936 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0113 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.2936 | 0.2936 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.2936 | 0.2936 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0113 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.4911 | 0.4587 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.4911 | 0.485 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.