Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | Zn-dependent alcohol dehydrogenase, AdhX | 0.014 | 0.0594 | 0.0594 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | quinone reductase Qor | 0.014 | 0.0594 | 0.0594 |
Leishmania major | quinone oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium tuberculosis | Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0804 | 0.8367 | 0.8264 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.014 | 0.0594 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0594 | 0.0594 |
Leishmania major | NADP-dependent alcohol dehydrogenase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase AdhC | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | dehydrogenase | 0.014 | 0.0594 | 0.0594 |
Leishmania major | zinc binding dehydrogenase-like protein | 0.014 | 0.0594 | 1 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase AdhD (aldehyde reductase) | 0.0943 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | NADPH:quinone reductase | 0.014 | 0.0594 | 0.5 |
Echinococcus granulosus | mitochondrial trans 2 enoyl coenzyme A reductase | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | short-chain dehydrogenase | 0.014 | 0.0594 | 0.0594 |
Trypanosoma cruzi | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Leishmania major | d-xylulose reductase, putative | 0.014 | 0.0594 | 1 |
Loa Loa (eye worm) | alcohol dehydrogenase class III | 0.0943 | 1 | 1 |
Toxoplasma gondii | Zn-containing alcohol dehydrogenase | 0.0943 | 1 | 1 |
Leishmania major | oxidoreductase-like protein | 0.014 | 0.0594 | 1 |
Echinococcus multilocularis | mitochondrial trans 2 enoyl coenzyme A reductase | 0.014 | 0.0594 | 0.5 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Leishmania major | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium tuberculosis | Probable zinc-type alcohol dehydrogenase (E subunit) AdhE1 | 0.0804 | 0.8367 | 0.8264 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0594 | 0.0594 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | polyketide synthase | 0.014 | 0.0594 | 0.0594 |
Trypanosoma brucei | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium leprae | Probable S-nitrosomycothiol reductase MscR | 0.0943 | 1 | 1 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | zinc-dependent alcohol dehydrogenase AdhE2 | 0.0943 | 1 | 1 |
Onchocerca volvulus | Putative alcohol dehydrogenase | 0.0943 | 1 | 1 |
Trypanosoma cruzi | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Schistosoma mansoni | alcohol dehydrogenase | 0.0943 | 1 | 1 |
Trypanosoma cruzi | nuclear receptor binding factor, putative | 0.014 | 0.0594 | 1 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase | 0.014 | 0.0594 | 0.5 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.014 | 0.0594 | 0.0594 |
Trypanosoma cruzi | NADP-dependent alcohol hydrogenase, putative | 0.014 | 0.0594 | 1 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.014 | 0.0594 | 0.0594 |
Onchocerca volvulus | 0.014 | 0.0594 | 0.0594 | |
Mycobacterium ulcerans | zinc-type alcohol dehydrogenase AdhD | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | NADP-dependent alcohol dehydrogenase Adh | 0.014 | 0.0594 | 0.0594 |
Trypanosoma brucei | oxidoreductase, putative | 0.014 | 0.0594 | 1 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD-dependent AdhB | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | NADPH quinone oxidoreductase FadB4 | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | quinone oxidoreductase | 0.014 | 0.0594 | 0.0594 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0594 | 0.0594 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Mycobacterium ulcerans | zinc-containing alcohol dehydrogenase NAD dependent AdhB | 0.0943 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase FadB5 | 0.014 | 0.0594 | 0.0594 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.014 | 0.0594 | 0.0594 |
Entamoeba histolytica | NADP-dependent alcohol dehydrogenase, putative | 0.014 | 0.0594 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.