Detailed information for compound 906685

Basic information

Technical information
  • TDR Targets ID: 906685
  • Name: N-(2-cyanophenyl)-2-[(5-ethyl-[1,2,4]triazino [5,6-b]indol-3-yl)sulfanyl]butanamide
  • MW: 416.499 | Formula: C22H20N6OS
  • H donors: 1 H acceptors: 5 LogP: 4.28 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(C(=O)Nc1ccccc1C#N)Sc1nnc2c(n1)n(CC)c1c2cccc1
  • InChi: 1S/C22H20N6OS/c1-3-18(21(29)24-16-11-7-5-9-14(16)13-23)30-22-25-20-19(26-27-22)15-10-6-8-12-17(15)28(20)4-2/h5-12,18H,3-4H2,1-2H3,(H,24,29)
  • InChiKey: QSIASWUQUQOIQE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-cyanophenyl)-2-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]butanamide
  • N-(2-cyanophenyl)-2-[(5-ethyl-[1,2,4]triazino[5,6-b]indol-3-yl)thio]butyramide
  • BAS 01521646
  • Oprea1_039785
  • Oprea1_239943
  • A1891/0079415

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus peregrin 0.0063 0.0092 0.009
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.0034 0.0266
Giardia lamblia Cathepsin B precursor 0.0082 0.0142 0.0515
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0116 0.0226 0.5
Onchocerca volvulus 0.0506 0.1207 1
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.02 0.1639
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0049 0.0056 0.0875
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0142 0.1158
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.005 0.0059 0.0057
Echinococcus granulosus thyroid hormone receptor alpha 0.0041 0.0038 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0082 0.0142 0.1158
Plasmodium vivax JmjC domain containing protein 0.0032 0.0013 0.0185
Brugia malayi tailless protein 0.0041 0.0038 0.0111
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0082 0.0142 0.014
Onchocerca volvulus Protein ultraspiracle homolog 0.0087 0.0153 0.1255
Schistosoma mansoni nuclear receptor 0.0041 0.0038 0.0035
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0082 0.0142 0.2275
Entamoeba histolytica hypothetical protein 0.0031 0.0012 0.0144
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0116 0.0226 0.0225
Brugia malayi Intermediate filament tail domain containing protein 0.0096 0.0175 0.0518
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0211 0.0465 0.1373
Entamoeba histolytica cysteine proteinase, putative 0.0159 0.0334 0.5401
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0116 0.0226 0.5
Schistosoma mansoni nuclear receptor 0.0041 0.0038 0.0035
Onchocerca volvulus 0.0271 0.0616 0.5092
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0087 0.0153 0.0453
Entamoeba histolytica cysteine proteinase 1, putative 0.0159 0.0334 0.5401
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0126 0.0367
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0038 0.0111
Brugia malayi hypothetical protein 0.0031 0.0012 0.0034
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0013 0.0099
Loa Loa (eye worm) hypothetical protein 0.0046 0.005 0.0147
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0038 0.0036
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.006 0.0483
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0038 0.0029 0.0027
Trypanosoma cruzi cysteine proteinase, putative 0.0159 0.0334 0.0981
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Brugia malayi Steroid receptor seven-up type 2 0.0087 0.0153 0.0453
Onchocerca volvulus 0.0271 0.0616 0.5092
Echinococcus granulosus intermediate filament protein 0.0096 0.0175 0.0173
Toxoplasma gondii cathepsin CPL 0.0271 0.0616 0.537
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0006
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0082 0.0142 0.2275
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0087 0.0153 0.0151
Entamoeba histolytica cysteine proteinase, putative 0.0194 0.0424 0.6864
Loa Loa (eye worm) hypothetical protein 0.0194 0.0424 0.1251
Entamoeba histolytica hypothetical protein 0.0031 0.0012 0.0144
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0082 0.0142 0.2275
Entamoeba histolytica serine/threonine protein kinase, putative 0.0211 0.0465 0.7537
Echinococcus granulosus snurportin 1 0.0231 0.0516 0.0514
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0263 0.077
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0087 0.0745
Plasmodium falciparum serine repeat antigen 1 0.0082 0.0142 0.2153
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0082 0.0142 0.1158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0194 0.0424 0.3497
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0044 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Plasmodium vivax heterochromatin protein 1, putative 0.0031 0.0012 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Onchocerca volvulus 0.0096 0.0175 0.1437
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0116 0.0226 0.5
Echinococcus multilocularis peptidase Clp (S14 family) 0.0076 0.0126 0.0124
Brugia malayi cathepsin F-like cysteine proteinase 0.0082 0.0142 0.0419
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0087 0.0153 0.0453
Brugia malayi Cathepsin L-like precursor 0.0194 0.0424 0.1251
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0046 0.005 0.0147
Brugia malayi nuclear hormone receptor 0.0041 0.0038 0.0111
Brugia malayi Nuclear hormone receptor-like 1 0.0087 0.0153 0.0453
Loa Loa (eye worm) CHromoDomain protein family member 0.0037 0.0027 0.0081
Onchocerca volvulus Cathepsin L homolog 0.0271 0.0616 0.5092
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0031 0.0012 0.0083
Brugia malayi Papain family cysteine protease containing protein 0.0082 0.0142 0.0419
Brugia malayi conserved hypotetical protein 0.0041 0.0038 0.0111
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0116 0.0226 0.3656
Schistosoma mansoni cellular tumor antigen P53 0.0036 0.0025 0.0022
Echinococcus multilocularis geminin 0.038 0.0891 0.0889
Brugia malayi Associated with TFs and helicases family protein 0.0031 0.0012 0.0034
Loa Loa (eye worm) hypothetical protein 0.0031 0.0011 0.0033
Onchocerca volvulus 0.0083 0.0142 0.1163
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0082 0.0142 0.0515
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0087 0.0153 0.0151
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Loa Loa (eye worm) hypothetical protein 0.0044 0.0046 0.0136
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0122 0.0996
Giardia lamblia Cathepsin B precursor 0.0082 0.0142 0.0515
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0331 0.0767 0.2265
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0271 0.0616 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0027 0.0003 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0044 0.0045 0.1916
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0056 0.0451
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0105 0.0103
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0082 0.0142 0.2153
Brugia malayi jmjC domain containing protein 0.0032 0.0013 0.004
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.005 0.0147
Brugia malayi RNA, U transporter 1 0.0062 0.0089 0.0263
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0082 0.0142 0.0419
Brugia malayi cathepsin F-like cysteine proteinase 0.0076 0.0126 0.0373
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0034
Toxoplasma gondii hypothetical protein 0.004 0.0035 0.0286
Echinococcus multilocularis neutral alpha glucosidase AB 0.013 0.0263 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Giardia lamblia Cathepsin B precursor 0.0481 0.1145 1
Brugia malayi hypothetical protein 0.0041 0.0038 0.0111
Brugia malayi latrophilin 2 splice variant baaae 0.0226 0.0503 0.1487
Loa Loa (eye worm) hypothetical protein 0.0078 0.0131 0.0387
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.137 0.3385 0.3384
Trichomonas vaginalis CAMK family protein kinase 0.0211 0.0465 0.3839
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0244 0.0548 0.4777
Schistosoma mansoni cathepsin S (C01 family) 0.0082 0.0142 0.014
Brugia malayi Cathepsin L-like precursor 0.0271 0.0616 0.1819
Plasmodium falciparum serine repeat antigen 5 0.0082 0.0142 0.2153
Trypanosoma cruzi DNA repair and recombination helicase protein PIF6, putative 0.0081 0.0139 0.0405
Plasmodium falciparum cysteine proteinase falcipain 3 0.0271 0.0616 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0271 0.0616 1
Brugia malayi jmjC domain containing protein 0.0244 0.0548 0.1619
Brugia malayi ecdysone receptor 0.0041 0.0038 0.0111
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0105 0.0103
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0044 0.0045 0.1172
Trichomonas vaginalis hypothetical protein 0.0031 0.0012 0.0079
Echinococcus multilocularis tumor protein p63 0.0245 0.0552 0.055
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0046 0.005 0.0048
Trypanosoma cruzi cysteine peptidase, putative 0.0271 0.0616 0.1814
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0031 0.0012 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0037 0.0026 0.0071
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0099 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.006 0.0483
Brugia malayi jmjC domain containing protein 0.0032 0.0013 0.004
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0105 0.0103
Brugia malayi Valyl-tRNA synthetase 0.0031 0.0012 0.0034
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0082 0.0142 0.014
Toxoplasma gondii cathepsin CPC1 0.0082 0.0142 0.1221
Echinococcus granulosus cathepsin L 0.0082 0.0142 0.014
Schistosoma mansoni lamin 0.0096 0.0175 0.0173
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0034
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0087 0.0153 0.0453
Toxoplasma gondii cathepsin B 0.0481 0.1145 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0244 0.0548 0.1619
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Entamoeba histolytica cysteine proteinase, putative 0.0271 0.0616 1
Giardia lamblia Hypothetical protein 0.0082 0.0142 0.0515
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Echinococcus multilocularis musashi 0.0096 0.0175 0.0173
Entamoeba histolytica hypothetical protein 0.0082 0.0142 0.2266
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0082 0.0142 0.2266
Onchocerca volvulus Cathepsin F homolog 0.0271 0.0616 0.5092
Brugia malayi Cathepsin L-like precursor 0.0271 0.0616 0.1819
Loa Loa (eye worm) steroid hormone receptor 0.0087 0.0153 0.0453
Plasmodium vivax vivapain-1 0.0159 0.0334 0.5406
Loa Loa (eye worm) hypothetical protein 0.0032 0.0013 0.004
Loa Loa (eye worm) hypothetical protein 0.0271 0.0616 0.1819
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Brugia malayi hypothetical protein 0.0351 0.0818 0.2417
Echinococcus granulosus cathepsin l cysteine peptidase 0.0271 0.0616 0.0614
Schistosoma mansoni cathepsin F (C01 family) 0.0194 0.0424 0.0422
Brugia malayi Latrophilin receptor protein 2 0.0105 0.0198 0.0584
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0013 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0087 0.0153 0.0453
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0006
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0031 0.0012 0.0034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.0131 0.0129
Schistosoma mansoni cathepsin C 0.0082 0.0142 0.014
Echinococcus multilocularis cpg binding protein 0.0092 0.0165 0.0163
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0082 0.0142 0.2275
Entamoeba histolytica cysteine proteinase 2 0.0159 0.0334 0.5401
Echinococcus granulosus peptidase Clp S14 family 0.0076 0.0126 0.0124
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0087 0.0153 0.1255
Echinococcus granulosus cathepsin L cysteine proteinase 0.0271 0.0616 0.0614
Loa Loa (eye worm) hypothetical protein 0.0037 0.0026 0.0078
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0087 0.0153 0.0453
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0481 0.1145 0.3378
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.004 0.0035 0.0384
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.137 0.3385 0.3384
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0037 0.0027 0.0026
Trypanosoma brucei polo-like protein kinase 0.0211 0.0465 0.4049
Trypanosoma cruzi cruzipain precursor, putative 0.0271 0.0616 0.1814
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Schistosoma mansoni alpha-glucosidase 0.0506 0.1208 0.1206
Brugia malayi jmjC domain containing protein 0.0125 0.0248 0.0732
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0271 0.0616 0.1819
Echinococcus multilocularis chromobox protein 1 0.0188 0.0408 0.0406
Loa Loa (eye worm) PHD-finger family protein 0.0061 0.0087 0.0258
Brugia malayi cathepsin L-like cysteine proteinase 0.0082 0.0142 0.0419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Brugia malayi nuclear receptor NHR-88 0.0087 0.0153 0.0453
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0013 0.0034
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0116 0.0226 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0271 0.0616 0.5092
Schistosoma mansoni hypothetical protein 0.038 0.0891 0.0889
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0081 0.0139 0.0405
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0142 0.1158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.006 0.0483
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0244 0.0548 0.0546
Schistosoma mansoni cpg binding protein 0.0092 0.0165 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Echinococcus multilocularis FTZ F1 alpha 0.0087 0.0153 0.0151
Echinococcus multilocularis transcription factor Dp 1 0.0141 0.0289 0.0288
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Toxoplasma gondii PHD-finger domain-containing protein 0.0061 0.0087 0.0745
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0105 0.0198 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0006
Brugia malayi MH2 domain containing protein 0.0104 0.0196 0.0579
Brugia malayi Heterochromatin protein 1 0.0188 0.0408 0.1205
Loa Loa (eye worm) hypothetical protein 0.0046 0.005 0.0147
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0588 0.1415 0.4179
Echinococcus multilocularis PHD finger protein rhinoceros 0.0061 0.0087 0.0085
Giardia lamblia Cathepsin B precursor 0.0082 0.0142 0.0515
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0013 0.0099
Onchocerca volvulus Cathepsin L homolog 0.0271 0.0616 0.5092
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0049 0.0056 0.0451
Echinococcus granulosus chromobox protein 1 0.0188 0.0408 0.0406
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0113 0.022 0.1807
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0211 0.0465 0.0463
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0116 0.0226 0.0225
Brugia malayi Papain family cysteine protease containing protein 0.0082 0.0142 0.0419
Loa Loa (eye worm) MH2 domain-containing protein 0.0104 0.0196 0.0579
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0046 0.005 0.0048
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0116 0.0226 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0087 0.0153 0.0151
Schistosoma mansoni hypothetical protein 0.0061 0.0087 0.0085
Brugia malayi Pre-SET motif family protein 0.0065 0.0099 0.0291
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0194 0.0424 0.1246
Schistosoma mansoni intermediate filament proteins 0.0096 0.0175 0.0173
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0159 0.0334 0.2903
Brugia malayi hypothetical protein 0.0449 0.1064 0.3143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Loa Loa (eye worm) hypothetical protein 0.0046 0.005 0.0147
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0027 0.0002 0.0006
Schistosoma mansoni hypothetical protein 0.0105 0.0198 0.0196
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0076 0.0126 0.551
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0078 0.0131 0.0129
Echinococcus granulosus chromobox protein 2 0.0031 0.0012 0.001
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0244 0.0548 0.0546
Echinococcus multilocularis lysosomal alpha glucosidase 0.0588 0.1415 0.1413
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0013 0.0011
Schistosoma mansoni cathepsin B (C01 family) 0.0082 0.0142 0.014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0082 0.0142 0.014
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Schistosoma mansoni chromobox protein 0.0188 0.0408 0.0406
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0034
Brugia malayi hypothetical protein 0.0041 0.0038 0.0111
Loa Loa (eye worm) hypothetical protein 0.0036 0.0025 0.0072
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0012 0.0079
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0012 0.0144
Trypanosoma cruzi PAB1-binding protein , putative 0.0037 0.0026 0.0071
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0096 0.0175 0.0518
Brugia malayi Protein cec-1. 0.0031 0.0012 0.0034
Echinococcus granulosus cathepsin b 0.137 0.3385 0.3384
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Schistosoma mansoni jumonji domain containing protein 0.0203 0.0445 0.0443
Echinococcus multilocularis peregrin 0.0063 0.0092 0.009
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0244 0.0548 0.4777
Giardia lamblia Cathepsin L precursor 0.0082 0.0142 0.0515
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0082 0.0142 0.014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0087 0.0153 0.0453
Entamoeba histolytica hypothetical protein, conserved 0.0081 0.0139 0.2226
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Schistosoma mansoni hypothetical protein 0.0226 0.0503 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Echinococcus granulosus geminin 0.038 0.0891 0.0889
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0006
Plasmodium vivax hypothetical protein, conserved 0.0061 0.0087 0.1387
Loa Loa (eye worm) hypothetical protein 0.0044 0.0046 0.0136
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Trichomonas vaginalis CAMK family protein kinase 0.0211 0.0465 0.3839
Schistosoma mansoni cpg binding protein 0.0092 0.0165 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0087 0.0153 0.0453
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0013 0.0011
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0042 0.004 0.0038
Onchocerca volvulus 0.0087 0.0153 0.1255
Echinococcus multilocularis cysteine protease 0.0271 0.0616 0.0614
Schistosoma mansoni hypothetical protein 0.0105 0.0198 0.0196
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0041 0.0038 0.0036
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0082 0.0142 0.2153
Brugia malayi PHD-finger family protein 0.0061 0.0087 0.0258
Echinococcus multilocularis thyroid hormone receptor alpha 0.0087 0.0153 0.0151
Trichomonas vaginalis conserved hypothetical protein 0.0105 0.02 0.1639
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0087 0.0153 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0087 0.0153 0.0453
Echinococcus multilocularis cysteine protease 0.0271 0.0616 0.0614
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Brugia malayi Papain family cysteine protease containing protein 0.0159 0.0334 0.0986
Giardia lamblia Cysteine protease 0.0082 0.0142 0.0515
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0082 0.0142 0.1158
Loa Loa (eye worm) hypothetical protein 0.137 0.3385 1
Brugia malayi Cathepsin L-like precursor 0.0271 0.0616 0.1819
Schistosoma mansoni hypothetical protein 0.0105 0.0198 0.0196
Loa Loa (eye worm) jmjC domain-containing protein 0.0125 0.0248 0.0732
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Brugia malayi Cathepsin L-like precursor 0.0076 0.0126 0.0373
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0087 0.0153 0.0151
Trichomonas vaginalis chromobox protein, putative 0.0113 0.022 0.1807
Brugia malayi Papain family cysteine protease containing protein 0.0271 0.0616 0.1819
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0087 0.0153 0.0453
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0076 0.0126 0.0373
Brugia malayi beta-lactamase family protein 0.0027 0.0002 0.0006
Echinococcus multilocularis cathepsin b 0.137 0.3385 0.3384
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0087 0.0153 0.0151
Trypanosoma brucei DNA repair and recombination helicase protein PIF6 0.0081 0.0139 0.12
Trichomonas vaginalis Heterochromatin protein, putative 0.0031 0.0012 0.0079
Echinococcus granulosus jumonji domain containing protein 0.0085 0.0147 0.0145
Entamoeba histolytica cysteine proteinase, putative 0.0271 0.0616 1
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0037 0.0027 0.0025
Echinococcus multilocularis cathepsin L 0.0159 0.0334 0.0332
Brugia malayi cathepsin Z-like cysteine proteinase 0.0082 0.0142 0.0419
Entamoeba histolytica cysteine protease, putative 0.0271 0.0616 1
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.004 0.0035 0.1458
Loa Loa (eye worm) hypothetical protein 0.0037 0.0027 0.008
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0105 0.0198 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.137 0.3385 1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0037 0.0027 0.0026
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0173 0.0369 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0166 0.0351 0.3055
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0082 0.0142 0.0515
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Loa Loa (eye worm) helicase 0.0031 0.0012 0.0034
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Loa Loa (eye worm) hypothetical protein 0.0449 0.1064 0.3143
Giardia lamblia Cathepsin L precursor 0.0082 0.0142 0.0515
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0231 0.0516 0.1523
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0087 0.0153 0.0151
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.006 0.0483
Loa Loa (eye worm) hypothetical protein 0.0083 0.0142 0.042
Schistosoma mansoni aldehyde dehydrogenase 0.0044 0.0045 0.0043
Echinococcus granulosus nuclear receptor nhr 48 0.0041 0.0038 0.0036
Echinococcus granulosus cathepsin l1 0.0271 0.0616 0.0614
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0006
Echinococcus granulosus Chromo domain 0.0031 0.0012 0.001
Onchocerca volvulus 0.0271 0.0616 0.5092
Onchocerca volvulus Alhambra homolog 0.0061 0.0087 0.0706
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Loa Loa (eye worm) beta-lactamase 0.0027 0.0002 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0013 0.0011
Giardia lamblia Rrm3p helicase 0.0081 0.0139 0.0492
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.013 0.0263 0.2161
Trypanosoma brucei glycosyl hydrolase-like protein 0.0049 0.0056 0.0475
Plasmodium vivax serine-repeat antigen (SERA) 0.0082 0.0142 0.2275
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0046 0.005 0.0048
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0082 0.0142 0.2153
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0056 0.0451
Loa Loa (eye worm) CXXC zinc finger family protein 0.0085 0.0149 0.044
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Schistosoma mansoni cathepsin s 0.0076 0.0126 0.0124
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0031 0.0012 0.001
Echinococcus multilocularis ATP dependent DNA helicase PIF1 0.0081 0.0139 0.0137
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0061 0.0088 0.0086
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.013 0.0263 0.0776
Loa Loa (eye worm) transcription factor SMAD2 0.0104 0.0196 0.0579
Loa Loa (eye worm) hypothetical protein 0.0105 0.0198 0.0584
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0082 0.0142 0.1158
Echinococcus granulosus FTZ F1 alpha 0.0087 0.0153 0.0151
Brugia malayi F/Y-rich N-terminus family protein 0.005 0.0059 0.0175
Brugia malayi beta-lactamase 0.0027 0.0002 0.0006
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0031 0.0012 0.0083
Schistosoma mansoni chromobox protein 0.0031 0.0012 0.001
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0082 0.0142 0.014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Brugia malayi Cathepsin L-like precursor 0.0271 0.0616 0.1819
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0043 0.0043 0.0041
Brugia malayi Bromodomain containing protein 0.0029 0.0006 0.0019
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0271 0.0616 0.0614
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0027 0.0003 0.0001
Echinococcus granulosus transcription factor Dp 1 0.0141 0.0289 0.0288
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0211 0.0465 0.4049
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.137 0.3385 0.3384
Echinococcus granulosus lamin dm0 0.0096 0.0175 0.0173
Trichomonas vaginalis CAMK family protein kinase 0.0211 0.0465 0.3839
Trichomonas vaginalis chromobox protein, putative 0.0113 0.022 0.1807
Loa Loa (eye worm) heterochromatin protein 1 0.0188 0.0408 0.1205
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0082 0.0142 0.2275
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0087 0.0153 0.0453
Schistosoma mansoni nuclear receptor nhr-48 0.0041 0.0038 0.0035
Loa Loa (eye worm) hypothetical protein 0.0053 0.0068 0.02
Mycobacterium ulcerans aldehyde dehydrogenase 0.0044 0.0045 0.1916
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0159 0.0334 0.0332
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0087 0.0153 0.0151
Loa Loa (eye worm) hypothetical protein 0.0082 0.0142 0.0419
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.006 0.0483
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0087 0.0153 0.0151
Echinococcus granulosus lamin 0.0096 0.0175 0.0173
Echinococcus multilocularis survival motor neuron protein 1 0.0351 0.0818 0.0816
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0087 0.0153 0.0453
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0013 0.0034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0082 0.0142 0.1158
Brugia malayi Papain family cysteine protease containing protein 0.0159 0.0334 0.0986
Plasmodium falciparum serine repeat antigen 7 0.0082 0.0142 0.2153
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0263 0.2161
Leishmania major alpha glucosidase II subunit, putative 0.013 0.0263 0.2279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0031 0.0012 0.0079
Brugia malayi SET domain containing protein 0.0035 0.0022 0.0066
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0116 0.0226 0.1963
Echinococcus granulosus neutral alpha glucosidase AB 0.013 0.0263 0.0261
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0046 0.005 0.0048
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0012 0.0144
Loa Loa (eye worm) hypothetical protein 0.0194 0.0424 0.1251
Schistosoma mansoni hypothetical protein 0.0105 0.0198 0.0196
Brugia malayi Cathepsin L-like cysteine proteinase 0.0194 0.0424 0.1251
Trichomonas vaginalis chromobox protein, putative 0.0188 0.0408 0.3367
Onchocerca volvulus 0.0082 0.0142 0.1158
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0013 0.0099
Loa Loa (eye worm) hypothetical protein 0.0331 0.0767 0.2265
Entamoeba histolytica cysteine protease, putative 0.0082 0.0142 0.2266
Loa Loa (eye worm) hypothetical protein 0.0029 0.0007 0.0019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Entamoeba histolytica cysteine protease, putative 0.0082 0.0142 0.2266
Brugia malayi Glycosyl hydrolases family 31 protein 0.0049 0.0056 0.0167
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0068 0.0105 0.0103
Echinococcus multilocularis GPCR, family 2 0.0105 0.0198 0.0196
Schistosoma mansoni peptidase Clp (S14 family) 0.0116 0.0226 0.0224
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0244 0.0548 0.0546
Trichomonas vaginalis conserved hypothetical protein 0.0082 0.0142 0.1158
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Schistosoma mansoni survival motor neuron protein 0.0072 0.0114 0.0112
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0049 0.0056 0.0451
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0038 0.0296
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.004 0.0035 0.0533
Schistosoma mansoni zinc finger protein 0.0041 0.0038 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0142 0.1158
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Trichomonas vaginalis maltase-glucoamylase, putative 0.013 0.0263 0.2161
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0013 0.0011
Plasmodium falciparum ataxin-2 like protein, putative 0.0037 0.0026 0.0242
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0087 0.0153 0.0453
Entamoeba histolytica cysteine protease, putative 0.0082 0.0142 0.2266
Loa Loa (eye worm) hypothetical protein 0.0082 0.0142 0.0419
Schistosoma mansoni bromodomain containing protein 0.0052 0.0066 0.0064
Leishmania major glycosyl hydrolase-like protein 0.0049 0.0056 0.0475
Brugia malayi Nuclear hormone receptor E75 0.0041 0.0038 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0142 0.1158
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0044 0.0045 0.0043
Schistosoma mansoni lamin 0.0096 0.0175 0.0173
Loa Loa (eye worm) hypothetical protein 0.0076 0.0126 0.0373
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0013 0.004
Loa Loa (eye worm) nuclear receptor NHR-67 0.0041 0.0038 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0087 0.0153 0.0453
Giardia lamblia Cathepsin L precursor 0.0082 0.0142 0.0515
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0041 0.0038 0.0111
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Loa Loa (eye worm) hypothetical protein 0.0046 0.005 0.0147
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0082 0.0142 0.2275
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0013 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0082 0.0142 0.1158
Entamoeba histolytica cysteine protease, putative 0.0082 0.0142 0.2266
Echinococcus granulosus PHD finger protein rhinoceros 0.0061 0.0087 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0087 0.0153 0.0453
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0087 0.0153 0.0453
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0116 0.0226 0.3556
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0082 0.0142 0.2275
Onchocerca volvulus 0.0085 0.0149 0.1217
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0481 0.1145 0.1143
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0099 0.0845
Giardia lamblia Cathepsin L precursor 0.0082 0.0142 0.0515
Brugia malayi orphan nuclear receptor NR2E1 0.0041 0.0038 0.0111
Trypanosoma cruzi major cysteine proteinase, putative 0.0082 0.0142 0.0413
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0263 0.2161
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0087 0.0153 0.0151
Echinococcus multilocularis Chromobox protein 3 0.0031 0.0012 0.001
Schistosoma mansoni jumonji/arid domain-containing protein 0.0125 0.0248 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0142 0.1158
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0031 0.0012 0.001
Trichomonas vaginalis CAMK family protein kinase 0.0211 0.0465 0.3839
Onchocerca volvulus 0.0041 0.0038 0.0294
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0031 0.0012 0.0083
Plasmodium vivax serine-repeat antigen (SERA) 0.0082 0.0142 0.2275
Loa Loa (eye worm) hypothetical protein 0.0046 0.005 0.0149
Trichomonas vaginalis chromobox protein, putative 0.0188 0.0408 0.3367
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0012 0.0079
Plasmodium falciparum ataxin-2 like protein, putative 0.0037 0.0026 0.0242
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.013 0.0263 0.4238
Brugia malayi CHD4 protein 0.0037 0.0027 0.0081
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0068 0.0105 0.031
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0038 0.0036
Echinococcus granulosus cysteine protease 0.0159 0.0334 0.0332
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0041 0.0038 0.0296
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.0139 0.1138
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0142 0.1158
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0244 0.0548 0.1614
Brugia malayi cathepsin B-like cysteine proteinase 0.137 0.3385 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0041 0.0038 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0087 0.0153 0.0151
Plasmodium falciparum serine repeat antigen 3 0.0082 0.0142 0.2153
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0087 0.0153 0.0151
Schistosoma mansoni hypothetical protein 0.038 0.0891 0.0889
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0087 0.0153 0.0151
Leishmania major cysteine peptidase A (CPA) 0.0271 0.0616 0.537
Echinococcus multilocularis lysosomal alpha glucosidase 0.0588 0.1415 0.1413
Echinococcus granulosus phd:f box containing protein 0.0032 0.0013 0.0011
Toxoplasma gondii cathepsin CPC2 0.0082 0.0142 0.1221
Schistosoma mansoni transcription factor LCR-F1 0.0027 0.0003 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0244 0.0548 0.1614
Loa Loa (eye worm) hypothetical protein 0.0226 0.0503 0.1487
Brugia malayi Cathepsin L-like precursor 0.0194 0.0424 0.1251
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Entamoeba histolytica cysteine protease, putative 0.0082 0.0142 0.2266
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Schistosoma mansoni chromobox protein 0.0031 0.0012 0.001
Brugia malayi cathepsin L-like precursor 0.0194 0.0424 0.1251
Echinococcus granulosus ecdysone induced protein 78C 0.0087 0.0153 0.0151
Trypanosoma cruzi DNA repair and recombination helicase protein PIF7, putative 0.0081 0.0139 0.0405
Loa Loa (eye worm) hypothetical protein 0.0082 0.0142 0.0419
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0068 0.0105 0.0103
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Brugia malayi fibroinase precursor 0.0082 0.0142 0.0419
Brugia malayi Probable ClpP-like protease 0.0116 0.0226 0.0669
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0087 0.0153 0.0453
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0068 0.0105 0.031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0183 0.0395 0.0393
Trichomonas vaginalis CAMK family protein kinase 0.0211 0.0465 0.3839
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0444 0.1053 0.3112
Brugia malayi nuclear hormone receptor family member nhr-6 0.0041 0.0038 0.0111
Echinococcus multilocularis cathepsin b 0.137 0.3385 0.3384
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0082 0.0142 0.0419
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0087 0.0153 0.0151
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0013 0.003
Entamoeba histolytica cysteine proteinase, putative 0.0159 0.0334 0.5401
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0263 0.077
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Plasmodium falciparum serine repeat antigen 8 0.0082 0.0142 0.2153
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Trypanosoma cruzi polo-like protein kinase, putative 0.0211 0.0465 0.1368
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0082 0.0142 0.1158
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0263 0.2161
Echinococcus multilocularis microtubule associated protein 2 0.3997 1 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0013 0.004
Echinococcus granulosus lysine specific demethylase 5A 0.0125 0.0248 0.0246
Trypanosoma brucei glucosidase, putative 0.013 0.0263 0.2279
Schistosoma mansoni hypothetical protein 0.0027 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0034
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0087 0.0153 0.0453
Onchocerca volvulus 0.0271 0.0616 0.5092
Onchocerca volvulus 0.0041 0.0038 0.0294
Loa Loa (eye worm) hypothetical protein 0.0082 0.0142 0.0419
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0013 0.004
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0041 0.0038 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0082 0.0142 0.1158
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0012 0.0155
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0038 0.0035
Trypanosoma cruzi cysteine peptidase, putative 0.0271 0.0616 0.1814
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0082 0.0142 0.1158
Mycobacterium ulcerans aldehyde dehydrogenase 0.0044 0.0045 0.1916
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0082 0.0142 0.0515
Trichomonas vaginalis CAMK family protein kinase 0.0211 0.0465 0.3839
Plasmodium vivax SET domain protein, putative 0.0065 0.0099 0.1573
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0159 0.0334 0.0981
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0013 0.004
Loa Loa (eye worm) hypothetical protein 0.0351 0.0818 0.2417
Schistosoma mansoni hypothetical protein 0.0072 0.0114 0.0112
Trypanosoma cruzi cysteine protease, putative 0.0159 0.0334 0.0981
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.006 0.0483
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Trypanosoma brucei PAB1-binding protein , putative 0.0037 0.0026 0.0211
Brugia malayi serine/threonine-protein kinase plk-2 0.0211 0.0465 0.1373
Echinococcus granulosus Nuclear hormone receptor HR96 0.0041 0.0038 0.0036
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0082 0.0142 0.014
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0087 0.0153 0.0453
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0038 0.0029 0.0027
Trichomonas vaginalis sucrase-isomaltase, putative 0.013 0.0263 0.2161
Giardia lamblia Cathepsin L-like protease 0.0082 0.0142 0.0515
Schistosoma mansoni nuclear hormone receptor 0.0041 0.0038 0.0035
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0061 0.0087 0.0085
Loa Loa (eye worm) latrophilin receptor protein 2 0.0105 0.0198 0.0584
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0051 0.0063 0.0187
Onchocerca volvulus 0.0271 0.0616 0.5092
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0013 0.0011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.137 0.3385 0.3384
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.0122 0.0996
Schistosoma mansoni alpha glucosidase 0.013 0.0263 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Brugia malayi hypothetical protein 0.0027 0.0003 0.0008
Loa Loa (eye worm) hypothetical protein 0.0082 0.0142 0.0419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0012 0.0155
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.006 0.0483
Trichomonas vaginalis maltase-glucoamylase, putative 0.0049 0.0056 0.0451
Trypanosoma cruzi major cysteine proteinase, putative 0.0082 0.0142 0.0413
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0056 0.0451
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Echinococcus multilocularis chromobox protein 2 0.0031 0.0012 0.001
Leishmania major hypothetical protein, conserved 0.0037 0.0026 0.0211
Loa Loa (eye worm) hypothetical protein 0.0027 0.0002 0.0006
Brugia malayi CXXC zinc finger family protein 0.0085 0.0149 0.044
Entamoeba histolytica cysteine proteinase, putative 0.0159 0.0334 0.5401
Brugia malayi nuclear receptor NHR-88 0.0041 0.0038 0.0111
Echinococcus granulosus cathepsin b 0.137 0.3385 0.3384
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Schistosoma mansoni hypothetical protein 0.0081 0.0139 0.0137
Brugia malayi Pre-SET motif family protein 0.0444 0.1053 0.3112
Brugia malayi nuclear receptor RXR 0.0046 0.005 0.0147
Schistosoma mansoni thyroid hormone receptor 0.0087 0.0153 0.0151
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.013 0.0263 0.2161
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0244 0.0548 0.1619
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0013 0.0011
Brugia malayi beta-lactamase family protein 0.0027 0.0002 0.0006
Onchocerca volvulus 0.0036 0.0025 0.0186
Loa Loa (eye worm) hypothetical protein 0.0049 0.0056 0.0167
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0041 0.0038 0.0036
Brugia malayi cathepsin Z-like cysteine proteinase 0.0082 0.0142 0.0419
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0076 0.0126 0.3372
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.006 0.0483
Schistosoma mansoni alpha-glucosidase 0.0506 0.1208 0.1206
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0034
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0046 0.005 0.0049
Plasmodium falciparum serine repeat antigen 2 0.0082 0.0142 0.2153
Onchocerca volvulus 0.0096 0.0176 0.1444
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0082 0.0142 0.1158
Entamoeba histolytica cysteine protease, putative 0.0082 0.0142 0.2266
Loa Loa (eye worm) hypothetical protein 0.0096 0.0175 0.0518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Onchocerca volvulus Bile acid receptor homolog 0.0087 0.0153 0.1255
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0012 0.0079
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1087 0.2672 0.2671
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0087 0.0153 0.0151
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0013 0.0011
Echinococcus multilocularis cathepsin L 0.0082 0.0142 0.014
Echinococcus granulosus ATP dependent DNA helicase PIF1 0.0081 0.0139 0.0137
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.005 0.0059 0.0057
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0041 0.0038 0.0111
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0031 0.0012 0.0144
Brugia malayi jmjC domain containing protein 0.0032 0.0013 0.004
Onchocerca volvulus 0.0449 0.1064 0.881
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0099 0.0097
Schistosoma mansoni coup transcription factor 0.0087 0.0153 0.0151
Echinococcus multilocularis cathepsin L cysteine protease 0.0271 0.0616 0.0614
Schistosoma mansoni cathepsin F (C01 family) 0.0271 0.0616 0.0614
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0116 0.0226 1
Giardia lamblia Kinase, PLK 0.0211 0.0465 0.357
Plasmodium falciparum cysteine proteinase falcipain 1 0.0159 0.0334 0.5334
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0038 0.0294
Brugia malayi photoreceptor-specific nuclear receptor 0.0087 0.0153 0.0453
Brugia malayi chromobox protein homolog 3 0.0105 0.02 0.059
Echinococcus granulosus histone lysine methyltransferase setb 0.0078 0.0131 0.0129
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0082 0.0142 0.014
Echinococcus multilocularis snurportin 1 0.0231 0.0516 0.0514
Plasmodium vivax unspecified product 0.0082 0.0142 0.2275
Onchocerca volvulus 0.0031 0.0012 0.0079
Brugia malayi Cathepsin L-like precursor 0.0271 0.0616 0.1819
Brugia malayi nuclear hormone receptor 0.0087 0.0153 0.0453
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Echinococcus multilocularis lamin 0.0096 0.0175 0.0173
Loa Loa (eye worm) DR-78 0.0041 0.0038 0.0111
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0082 0.0142 0.0419
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0056 0.0451
Entamoeba histolytica DNA repair and recombination protein, putative 0.0081 0.0139 0.2226
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0105 0.0198 0.0196
Echinococcus granulosus cpg binding protein 0.0092 0.0165 0.0163
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Leishmania major hypothetical protein, conserved 0.0032 0.0013 0.0099
Brugia malayi steroid hormone receptor 0.0087 0.0153 0.0453
Brugia malayi Bromodomain containing protein 0.0063 0.0092 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0082 0.0142 0.1158
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0078 0.0131 0.0129
Trypanosoma brucei cysteine peptidase C (CPC) 0.0481 0.1145 1
Brugia malayi intermediate filament protein 0.0096 0.0175 0.0518
Loa Loa (eye worm) hypothetical protein 0.0076 0.0126 0.0373
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.013 0.0263 0.4238
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0211 0.0465 0.0463
Schistosoma mansoni cathepsin F (C01 family) 0.0271 0.0616 0.0614
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0334 0.2753
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0263 0.2161
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0012 0.0079
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0087 0.0153 0.0453
Loa Loa (eye worm) fibroinase 0.0271 0.0616 0.1819
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0012 0.0079
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0041 0.0038 0.0294
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Schistosoma mansoni steroid hormone receptor ad4bp 0.0087 0.0153 0.0151
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0049 0.0056 0.0161
Giardia lamblia Cathepsin B precursor 0.0481 0.1145 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0044 0.0045 0.0376
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0271 0.0616 0.1819
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0105 0.0103
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0041 0.0038 0.0036
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0263 0.2161
Plasmodium falciparum serine repeat antigen 6 0.0082 0.0142 0.2153
Giardia lamblia Hypothetical protein 0.0082 0.0142 0.0515
Loa Loa (eye worm) hypothetical protein 0.0041 0.0038 0.0111
Giardia lamblia Cathepsin L-like protease 0.0082 0.0142 0.0515
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.013 0.0263 0.2279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0096 0.0176 0.0174
Brugia malayi hypothetical protein 0.0037 0.0026 0.0078
Schistosoma mansoni retinoic acid receptor RXR 0.0087 0.0153 0.0151
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0159 0.0334 0.0332
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0082 0.0142 0.0419
Echinococcus granulosus GPCR family 2 0.0105 0.0198 0.0196
Brugia malayi nuclear receptor NHR-67 0.0041 0.0038 0.0111
Echinococcus multilocularis chromobox protein 1 0.0188 0.0408 0.0406
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0081 0.0139 0.12
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0087 0.0153 0.0151
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0006 0.0004
Schistosoma mansoni RAR-like nuclear receptor 0.0087 0.0153 0.0151
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0027 0.0002 0.0006
Loa Loa (eye worm) hypothetical protein 0.0116 0.0227 0.0669
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0049 0.0056 0.0161
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Echinococcus multilocularis ecdysone induced protein 78C 0.0087 0.0153 0.0151
Plasmodium falciparum serine repeat antigen 4 0.0082 0.0142 0.2153
Brugia malayi M-phase phosphoprotein, mpp8 0.0031 0.0012 0.0034
Brugia malayi ecdysteroid receptor 0.0087 0.0153 0.0453
Brugia malayi Cathepsin L-like precursor 0.0271 0.0616 0.1819
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0105 0.0198 0.0196
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0041 0.0038 0.0036
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0082 0.0142 0.2275
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0082 0.0142 0.014
Echinococcus granulosus dnaJ subfamily B 0.0918 0.2245 0.2243
Schistosoma mansoni nuclear hormone receptor 0.0087 0.0153 0.0151
Loa Loa (eye worm) hypothetical protein 0.0094 0.0171 0.0505
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0244 0.0548 0.0546
Brugia malayi Papain family cysteine protease containing protein 0.0082 0.0142 0.0419
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0031 0.0012 0.001
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Schistosoma mansoni lipoxygenase 0.0042 0.004 0.0037
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0068 0.0105 0.0103
Trichomonas vaginalis CAMK family protein kinase 0.0211 0.0465 0.3839
Trypanosoma cruzi cysteine peptidase, putative 0.0159 0.0334 0.0981
Echinococcus multilocularis jumonji domain containing protein 0.0085 0.0147 0.0145
Echinococcus multilocularis cathepsin L cysteine protease 0.0271 0.0616 0.0614
Loa Loa (eye worm) hypothetical protein 0.0116 0.0226 0.0669
Onchocerca volvulus 0.0271 0.0616 0.5092
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0105 0.0198 0.0584
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0049 0.0056 0.0451
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0013 0.0011
Leishmania major cathepsin L-like protease 0.0271 0.0616 0.537
Loa Loa (eye worm) nuclear hormone receptor 0.0041 0.0038 0.0111
Giardia lamblia Cysteine protease 0.0082 0.0142 0.0515
Echinococcus multilocularis lysine specific demethylase 5A 0.0118 0.0232 0.023
Echinococcus granulosus chromobox protein 1 0.0188 0.0408 0.0406
Schistosoma mansoni hypothetical protein 0.0918 0.2245 0.2243
Echinococcus granulosus survival motor neuron protein 1 0.0351 0.0818 0.0816
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0046 0.005 0.0049
Echinococcus multilocularis lamin dm0 0.0096 0.0175 0.0173
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0331 0.0767 0.2265
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0271 0.0616 0.537
Echinococcus granulosus Chromobox protein 3 0.0031 0.0012 0.001
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0244 0.0548 0.8894
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0087 0.0153 0.0151
Leishmania major PIF1 helicase-like protein, putative,DNA repair and recombination protein, mitochondrial precursor, putative 0.0081 0.0139 0.12
Onchocerca volvulus Serine\/threonine kinase homolog 0.0211 0.0465 0.3839
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0042 0.004 0.0038
Brugia malayi Glycosyl hydrolases family 31 protein 0.0588 0.1415 0.4179
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0105 0.02 0.1639
Plasmodium vivax unspecified product 0.0159 0.0334 0.5406
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0197 0.1615
Brugia malayi Glycosyl hydrolases family 31 protein 0.013 0.0263 0.0776
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0116 0.0226 0.1963
Loa Loa (eye worm) ctsf protein 0.0271 0.0616 0.1819
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0072 0.0114 0.0338
Brugia malayi hypothetical protein 0.0046 0.005 0.0147
Loa Loa (eye worm) hypothetical protein 0.0105 0.02 0.059
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Brugia malayi Calcitonin receptor-like protein seb-1 0.0331 0.0767 0.2265
Onchocerca volvulus 0.0194 0.0424 0.3497
Schistosoma mansoni hypothetical protein 0.0231 0.0516 0.0514
Loa Loa (eye worm) hypothetical protein 0.0082 0.0142 0.0419
Entamoeba histolytica cysteine protease, putative 0.0159 0.0334 0.5401
Plasmodium vivax vivapain-2 0.0271 0.0616 1
Trichomonas vaginalis set domain proteins, putative 0.0506 0.1207 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0034
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0116 0.0226 1
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0013 0.0011
Schistosoma mansoni kinase 0.0107 0.0204 0.0202
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0244 0.0548 0.0546
Echinococcus granulosus cathepsin l1 0.0194 0.0424 0.0422
Loa Loa (eye worm) intermediate filament protein 0.0096 0.0175 0.0518
Toxoplasma gondii aldehyde dehydrogenase 0.0044 0.0045 0.0376
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0159 0.0334 0.2903
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0194 0.0424 0.3497
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0076 0.0126 0.3372
Giardia lamblia Cathepsin L precursor 0.0082 0.0142 0.0515
Schistosoma mansoni jumonji/arid domain-containing protein 0.0125 0.0248 0.0246
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0082 0.0142 0.1158
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0041 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.0031 0.0012 0.0034
Giardia lamblia Cysteine protease 0.0082 0.0142 0.0515
Entamoeba histolytica hypothetical protein 0.0031 0.0012 0.0144
Trichomonas vaginalis alpha-glucosidase, putative 0.0049 0.0056 0.0451
Echinococcus multilocularis Chromo domain 0.0031 0.0012 0.001
Echinococcus granulosus cathepsin L cysteine protease 0.0159 0.0334 0.0332
Giardia lamblia Cathepsin B precursor 0.0082 0.0142 0.0515
Toxoplasma gondii preprocathepsin c precursor, putative 0.0082 0.0142 0.1221
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0271 0.0616 0.5092
Brugia malayi cathepsin L precursor 0.0082 0.0142 0.0419
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0271 0.0616 0.5092
Plasmodium vivax ataxin-2 like protein, putative 0.0037 0.0026 0.0393
Plasmodium vivax unspecified product 0.0076 0.0126 0.2023
Plasmodium vivax vivapain-3 0.0159 0.0334 0.5406
Giardia lamblia Cysteine protease 0.0082 0.0142 0.0515
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0082 0.0142 0.0515
Toxoplasma gondii LsmAD domain-containing protein 0.0037 0.0026 0.0211
Entamoeba histolytica cysteine proteinase, putative 0.0159 0.0334 0.5401
Brugia malayi hypothetical protein 0.0046 0.005 0.0147
Trypanosoma cruzi cysteine peptidase, putative 0.0271 0.0616 0.1814
Onchocerca volvulus Cathepsin L homolog 0.0082 0.0142 0.1158
Giardia lamblia Encystation-specific protease 0.0082 0.0142 0.0515
Giardia lamblia Cathepsin B precursor 0.0481 0.1145 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0481 0.1145 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0006 0.0004
Schistosoma mansoni microtubule-associated protein tau 0.3997 1 1
Brugia malayi Bromodomain containing protein 0.0061 0.0088 0.026
Loa Loa (eye worm) hypothetical protein 0.0076 0.0126 0.0373
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0082 0.0142 0.2266
Schistosoma mansoni hypothetical protein 0.0031 0.0012 0.001
Brugia malayi jmjC domain containing protein 0.0032 0.0013 0.004
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0006 0.0019
Loa Loa (eye worm) cathepsin B 0.0481 0.1145 0.3382
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0159 0.0334 0.2753
Brugia malayi cytoplasmic intermediate filament protein 0.0051 0.0063 0.0187
Plasmodium falciparum phd finger protein, putative 0.0061 0.0087 0.1251
Loa Loa (eye worm) jmjC domain-containing protein 0.0126 0.025 0.0739
Trypanosoma cruzi cysteine proteinase, putative 0.0159 0.0334 0.0981
Giardia lamblia Cathepsin B precursor 0.0082 0.0142 0.0515
Plasmodium falciparum serine repeat antigen 9 0.0082 0.0142 0.2153
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0087 0.0153 0.0453
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0159 0.0334 0.0332
Loa Loa (eye worm) cysteine protease 0.0271 0.0616 0.1819
Brugia malayi Nuclear hormone receptor-like 1 0.0046 0.005 0.0147
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0271 0.0616 0.0614
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0271 0.0616 0.5092
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0087 0.0153 0.0151
Loa Loa (eye worm) hypothetical protein 0.0061 0.0087 0.0258
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0087 0.0153 0.0151
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0082 0.0142 0.2275
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0082 0.0142 0.014
Onchocerca volvulus 0.0096 0.0175 0.1437
Brugia malayi nuclear hormone receptor family member odr-7 0.0041 0.0038 0.0111
Echinococcus multilocularis dnaJ subfamily B 0.0918 0.2245 0.2243
Trypanosoma cruzi cysteine peptidase, putative 0.0271 0.0616 0.1814
Schistosoma mansoni cpg binding protein 0.0085 0.0149 0.0147
Loa Loa (eye worm) hypothetical protein 0.0194 0.0424 0.1251
Schistosoma mansoni serine/threonine protein kinase 0.0211 0.0465 0.0463
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0082 0.0142 0.2275
Echinococcus granulosus lysosomal alpha glucosidase 0.0588 0.1415 0.1413
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0041 0.0038 0.0035
Onchocerca volvulus 0.0271 0.0616 0.5092
Loa Loa (eye worm) hypothetical protein 0.0046 0.005 0.0147
Schistosoma mansoni chromobox protein 0.0188 0.0408 0.0406
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0031 0.0012 0.001
Echinococcus granulosus cathepsin L 0.0159 0.0334 0.0332
Trypanosoma brucei DNA repair and recombination helicase protein PIF7 0.0081 0.0139 0.12
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0197 0.1615
Plasmodium vivax vivapain-2 0.0271 0.0616 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0126 0.0367
Schistosoma mansoni aldehyde dehydrogenase 0.0044 0.0045 0.0043
Onchocerca volvulus 0.0031 0.0012 0.0079
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Onchocerca volvulus 0.034 0.079 0.654
Giardia lamblia Cathepsin L precursor 0.0082 0.0142 0.0515
Onchocerca volvulus 0.0072 0.0114 0.0932
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0041 0.0038 0.0035
Loa Loa (eye worm) hypothetical protein 0.0087 0.0153 0.0453
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0481 0.1145 0.9482
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0012 0.0079
Brugia malayi nuclear receptor RXR 0.0041 0.0038 0.0111
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0076 0.0126 0.0373
Echinococcus granulosus tumor protein p63 0.0245 0.0552 0.055
Trypanosoma cruzi polo-like protein kinase, putative 0.0211 0.0465 0.1368
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0087 0.0153 0.0151

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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