Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0048 | 0.0409 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0038 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0048 | 0.0409 | 0.0409 |
Loa Loa (eye worm) | carboxylesterase | 0.0048 | 0.0409 | 0.0409 |
Onchocerca volvulus | 0.0048 | 0.0409 | 0.5 | |
Trypanosoma brucei | cytochrome P450, putative | 0.0038 | 0 | 0.5 |
Leishmania major | cytochrome p450-like protein | 0.0038 | 0 | 0.5 |
Onchocerca volvulus | 0.0048 | 0.0409 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0409 | 0.0409 |
Onchocerca volvulus | 0.0048 | 0.0409 | 0.5 | |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0048 | 0.0409 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0409 | 0.0409 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0038 | 0 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0048 | 0.0409 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0048 | 0.0409 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0287 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0048 | 0.0409 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Brugia malayi | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Echinococcus multilocularis | acetylcholinesterase | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Echinococcus multilocularis | acetylcholinesterase | 0.0287 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0287 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0287 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0.0409 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0409 | 0.0409 |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0409 | 0.0409 |
Loa Loa (eye worm) | carboxylesterase | 0.0287 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0.0409 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0287 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0409 | 0.0409 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0048 | 0.0409 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.