Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1039 | 0.3084 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0715 | 0.0981 | 0.0981 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2106 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1039 | 0.3084 | 0.3084 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2106 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1039 | 0.3084 | 1 |
Onchocerca volvulus | 0.1039 | 0.3084 | 1 | |
Onchocerca volvulus | 0.1039 | 0.3084 | 1 | |
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2106 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0715 | 0.0981 | 0.0981 |
Giardia lamblia | Cathepsin B precursor | 0.0816 | 0.164 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.1039 | 0.3084 | 1 |
Onchocerca volvulus | 0.1039 | 0.3084 | 1 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1039 | 0.3084 | 0.2332 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2106 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1039 | 0.3084 | 0.3084 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0816 | 0.164 | 0.5319 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1039 | 0.3084 | 0.2332 |
Onchocerca volvulus | Cathepsin F homolog | 0.1039 | 0.3084 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1039 | 0.3084 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1039 | 0.3084 | 0.3084 |
Onchocerca volvulus | 0.1039 | 0.3084 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1039 | 0.3084 | 0.3084 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1039 | 0.3084 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.1039 | 0.3084 | 0.2332 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1039 | 0.3084 | 0.2332 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0715 | 0.0981 | 0.3182 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1039 | 0.3084 | 0.3084 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1039 | 0.3084 | 0.3084 |
Brugia malayi | Cathepsin L-like precursor | 0.0715 | 0.0981 | 0.0981 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1039 | 0.3084 | 0.3084 |
Brugia malayi | Cathepsin L-like precursor | 0.1039 | 0.3084 | 0.3084 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Plasmodium vivax | vivapain-2 | 0.1039 | 0.3084 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0715 | 0.0981 | 0.0981 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1039 | 0.3084 | 0.3084 |
Onchocerca volvulus | 0.1039 | 0.3084 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0816 | 0.164 | 0.5 |
Toxoplasma gondii | cathepsin CPL | 0.1039 | 0.3084 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0715 | 0.0981 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1039 | 0.3084 | 0.3084 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1039 | 0.3084 | 0.3084 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1039 | 0.3084 | 0.3084 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1039 | 0.3084 | 0.3084 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1039 | 0.3084 | 0.3084 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1039 | 0.3084 | 0.2332 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1039 | 0.3084 | 0.3084 |
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0816 | 0.164 | 0.164 |
Loa Loa (eye worm) | cathepsin B | 0.0816 | 0.164 | 0.0731 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Onchocerca volvulus | 0.1039 | 0.3084 | 1 | |
Echinococcus granulosus | cathepsin b | 0.2106 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0715 | 0.0981 | 0.0981 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2106 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.2106 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2106 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2106 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1039 | 0.3084 | 0.2332 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0816 | 0.164 | 0.164 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1039 | 0.3084 | 0.3084 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Plasmodium vivax | vivapain-2 | 0.1039 | 0.3084 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1039 | 0.3084 | 0.3084 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0715 | 0.0981 | 0.0981 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0816 | 0.164 | 0.5319 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1039 | 0.3084 | 0.3084 |
Giardia lamblia | Cathepsin B precursor | 0.0816 | 0.164 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.1039 | 0.3084 | 0.3084 |
Echinococcus granulosus | cathepsin l1 | 0.1039 | 0.3084 | 0.3084 |
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1039 | 0.3084 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1039 | 0.3084 | 0.3084 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0715 | 0.0981 | 0.0981 |
Leishmania major | cysteine peptidase A (CPA) | 0.1039 | 0.3084 | 1 |
Leishmania major | cathepsin L-like protease | 0.1039 | 0.3084 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1039 | 0.3084 | 1 |
Echinococcus multilocularis | cathepsin b | 0.2106 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1039 | 0.3084 | 1 |
Onchocerca volvulus | 0.1039 | 0.3084 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.1039 | 0.3084 | 0.3084 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0715 | 0.0981 | 0.3182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1039 | 0.3084 | 0.3084 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.