Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0136 | 0.2498 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0136 | 0.2498 | 0.1851 |
Brugia malayi | Cathepsin L-like precursor | 0.0136 | 0.2498 | 0.2498 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0136 | 0.2498 | 0.2498 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0136 | 0.2498 | 1 |
Onchocerca volvulus | 0.0136 | 0.2498 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0136 | 0.2498 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0136 | 0.2498 | 0.2498 |
Giardia lamblia | Cathepsin B precursor | 0.0122 | 0.1916 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0122 | 0.1916 | 0.767 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0094 | 0.0795 | 0.0795 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0136 | 0.2498 | 0.2498 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0136 | 0.2498 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0136 | 0.2498 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0136 | 0.2498 | 0.1851 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0136 | 0.2498 | 0.2498 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0136 | 0.2498 | 0.2498 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0122 | 0.1916 | 0.1916 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0136 | 0.2498 | 0.2498 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0321 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0321 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0136 | 0.2498 | 0.2498 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0136 | 0.2498 | 0.2498 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0136 | 0.2498 | 0.2498 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0136 | 0.2498 | 0.2498 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0122 | 0.1916 | 0.1218 |
Onchocerca volvulus | 0.0136 | 0.2498 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Onchocerca volvulus | 0.0136 | 0.2498 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0136 | 0.2498 | 0.2498 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0136 | 0.2498 | 0.2498 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0136 | 0.2498 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0136 | 0.2498 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0136 | 0.2498 | 0.2498 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0094 | 0.0795 | 0.0795 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0122 | 0.1916 | 0.1916 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0122 | 0.1916 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0136 | 0.2498 | 0.2498 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Onchocerca volvulus | 0.0136 | 0.2498 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0094 | 0.0795 | 0.0795 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0136 | 0.2498 | 0.2498 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0321 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0321 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0136 | 0.2498 | 0.1851 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0136 | 0.2498 | 0.2498 |
Brugia malayi | Cathepsin L-like precursor | 0.0136 | 0.2498 | 0.2498 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0094 | 0.0795 | 0.0795 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.2498 | 0.1851 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0136 | 0.2498 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0122 | 0.1916 | 0.5 |
Loa Loa (eye worm) | cysteine protease | 0.0136 | 0.2498 | 0.1851 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0122 | 0.1916 | 0.767 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0136 | 0.2498 | 0.1851 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0094 | 0.0795 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0136 | 0.2498 | 0.2498 |
Echinococcus multilocularis | cathepsin b | 0.0321 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0136 | 0.2498 | 0.2498 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0094 | 0.0795 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Echinococcus granulosus | cathepsin b | 0.0321 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Plasmodium vivax | vivapain-2 | 0.0136 | 0.2498 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0094 | 0.0795 | 0.0795 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0094 | 0.0795 | 0.3182 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0136 | 0.2498 | 0.2498 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0136 | 0.2498 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0136 | 0.2498 | 1 |
Leishmania major | cathepsin L-like protease | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0136 | 0.2498 | 0.2498 |
Onchocerca volvulus | 0.0136 | 0.2498 | 1 | |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0094 | 0.0795 | 0.0795 |
Echinococcus granulosus | cathepsin l1 | 0.0136 | 0.2498 | 0.2498 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Onchocerca volvulus | 0.0136 | 0.2498 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0321 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0136 | 0.2498 | 1 |
Plasmodium vivax | vivapain-2 | 0.0136 | 0.2498 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0136 | 0.2498 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0136 | 0.2498 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0321 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0321 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0094 | 0.0795 | 0.0795 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0136 | 0.2498 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.