Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.7424 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.7424 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.4163 | 0.4395 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.5463 | 0.4979 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0064 | 0.7424 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0535 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.9228 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0064 | 0.7424 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.2951 | 0.3975 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.724 | 0.9752 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0064 | 0.7424 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.2951 | 0.3975 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0064 | 0.7424 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.2617 | 0.2684 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0535 | 0.0721 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.5463 | 0.5833 |
Schistosoma mansoni | bromodomain containing protein | 0.0067 | 0.7886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.2617 | 0.3318 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.7424 | 0.9414 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.5463 | 0.4979 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0535 | 0.0679 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0064 | 0.7424 | 0.9414 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3391 | 0.3541 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0064 | 0.7424 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.3378 | 0.2673 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0191 | 0.0242 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0064 | 0.7424 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.2617 | 0.183 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.724 | 0.9752 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.5463 | 0.5833 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.3818 | 0.4014 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.