Detailed information for compound 907806

Basic information

Technical information
  • TDR Targets ID: 907806
  • Name: methyl 4-[[4,6-bis(propan-2-ylamino)-1,3,5-tr iazin-2-yl]oxy]benzoate
  • MW: 345.396 | Formula: C17H23N5O3
  • H donors: 2 H acceptors: 4 LogP: 3.92 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)c1ccc(cc1)Oc1nc(NC(C)C)nc(n1)NC(C)C
  • InChi: 1S/C17H23N5O3/c1-10(2)18-15-20-16(19-11(3)4)22-17(21-15)25-13-8-6-12(7-9-13)14(23)24-5/h6-11H,1-5H3,(H2,18,19,20,21,22)
  • InChiKey: LQGRYQGPYYGMNJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • methyl 4-[[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]oxy]benzoate
  • 4-[[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]oxy]benzoic acid methyl ester
  • 4-[[4,6-bis(isopropylamino)-s-triazin-2-yl]oxy]benzoic acid methyl ester
  • ChemDiv1_003192
  • BIM-0013988.P001
  • Oprea1_872448
  • Oprea1_198223
  • 4-(4,6-Bis-isopropylamino-[1,3,5]triazin-2-yloxy)-benzoic acid methyl ester
  • BAS 00609079
  • STOCK1S-11069
  • MLS000712616
  • SMR000282383
  • ZINC00182387
  • CBMicro_013957

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens glucagon-like peptide 1 receptor Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Loa Loa (eye worm) pigment dispersing factor receptor c glucagon-like peptide 1 receptor 463 aa 388 aa 25.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0126 0.0473 0.1397
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0015 0.001
Onchocerca volvulus 0.0054 0.0134 0.0182
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis cathepsin b 0.0985 0.4507 0.6826
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Trichomonas vaginalis penicillin-binding protein, putative 0.0179 0.072 0.4673
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0499 0.2224 0.336
Echinococcus granulosus lysosomal alpha glucosidase 0.0164 0.0651 0.0973
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0041 0.0072 0.0068
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0064 0.0126
Onchocerca volvulus 0.0095 0.0326 0.0473
Onchocerca volvulus 0.0527 0.2356 0.3557
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0985 0.4507 0.4504
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0064 0.018 0.0257
Trypanosoma cruzi cysteine protease, putative 0.0071 0.0212 0.0454
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0054 0.0049
Leishmania major oligopeptidase b 0.0215 0.089 0.2647
Trichomonas vaginalis PIKK family atypical protein kinase 0.0154 0.0603 0.3917
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Leishmania major cysteine peptidase A (CPA) 0.0182 0.0735 0.2182
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0353 0.154 0.3407
Mycobacterium leprae Probable lipase LipE 0.0179 0.072 0.8016
Loa Loa (eye worm) hypothetical protein 0.007 0.0207 0.03
Onchocerca volvulus 0.0034 0.0037 0.0034
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0031 0.0031
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0182 0.0735 0.1102
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0152 0.0594 0.0887
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0985 0.4507 0.4504
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0029 0.0015 0.001
Echinococcus granulosus GPCR family 2 0.0032 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0139 0.0531 0.3446
Schistosoma mansoni myosin xvIII 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Mycobacterium ulcerans beta-lactamase 0.0179 0.072 0.7977
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0051 0.0038
Plasmodium vivax vivapain-2 0.0182 0.0735 1
Echinococcus multilocularis somatostatin receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0032 0.0031 0.0033
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0029 0.0015 0.0007
Brugia malayi putative neuropeptide receptor NPR1 0.0029 0.0015 0.0012
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0091
Giardia lamblia Cathepsin B precursor 0.0353 0.154 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0182 0.0735 0.11
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0067 0.0062
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0353 0.154 0.4594
Echinococcus multilocularis zinc finger protein 0.0037 0.0051 0.0062
Toxoplasma gondii hypothetical protein 0.004 0.0067 0.0188
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Giardia lamblia Cathepsin B precursor 0.0353 0.154 1
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0064 0.018 0.0262
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Onchocerca volvulus 0.004 0.0067 0.0079
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0031 0.0037
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0029 0.0015 0.001
Echinococcus granulosus cathepsin L cysteine proteinase 0.0182 0.0735 0.11
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0029 0.0015 0.0012
Brugia malayi AKH receptor 0.0029 0.0015 0.0012
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) jmjC domain-containing protein 0.0135 0.0515 0.0768
Mycobacterium tuberculosis Probable peptidase 0.0215 0.089 0.165
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Toxoplasma gondii PLU-1 family protein 0.0042 0.0078 0.0238
Schistosoma mansoni microtubule-associated protein tau 0.0675 0.305 0.3046
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0164 0.0651 0.0974
Echinococcus multilocularis dnaJ subfamily B 0.0424 0.1872 0.2826
Schistosoma mansoni cathepsin F (C01 family) 0.0182 0.0735 0.0731
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0051 0.0097
Loa Loa (eye worm) hypothetical protein 0.036 0.1573 0.2373
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0139 0.0531 0.3446
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0054 0.0066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0056 0.0144 0.0203
Loa Loa (eye worm) MBCTL1 0.0092 0.0312 0.046
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0154 0.0603 0.1786
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0139 0.0531 0.0526
Brugia malayi ORL1-like opioid receptor 0.0029 0.0015 0.0012
Echinococcus multilocularis aminopeptidase N 0.0036 0.0046 0.0055
Brugia malayi Cathepsin L-like cysteine proteinase 0.0182 0.0735 0.1105
Schistosoma mansoni sodium/chloride dependent transporter 0.0235 0.0984 0.098
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0985 0.4507 0.4504
Loa Loa (eye worm) hypothetical protein 0.0041 0.0074 0.0098
Brugia malayi fibroinase precursor 0.0071 0.0212 0.0311
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0064 0.017
Trypanosoma brucei RNA helicase, putative 0.2154 1 1
Giardia lamblia Hypothetical protein 0.0071 0.0212 0.1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis histone acetyltransferase MYST2 0.0092 0.0312 0.0458
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus granulosus muscleblind protein 0.0152 0.0594 0.0886
Echinococcus granulosus cathepsin l cysteine peptidase 0.0182 0.0735 0.11
Onchocerca volvulus 0.0031 0.0024 0.0014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.017 0.1463
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0017 0.011
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0067 0.0062
Echinococcus multilocularis sex peptide receptor 0.0029 0.0015 0.0007
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.017 0.1463
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Echinococcus multilocularis dro:myosuppressin receptor 0.0029 0.0015 0.0007
Echinococcus granulosus chromobox protein 1 0.0081 0.026 0.038
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0036 0.0049 0.002
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.0317 0.0312
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0179 0.072 0.1323
Brugia malayi Peptidase family M1 containing protein 0.0036 0.0046 0.006
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0036 0.0046 0.0087
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Brugia malayi hypothetical protein 0.036 0.1573 0.2376
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0067 0.0086
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0154 0.0603 0.0599
Brugia malayi putative neuropeptide receptor 0.0029 0.0015 0.0012
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0029 0.0015 0.0007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0182 0.0177
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Schistosoma mansoni growth hormone secretagogue receptor 0.0029 0.0015 0.001
Plasmodium falciparum serine repeat antigen 4 0.0071 0.0212 0.2772
Onchocerca volvulus 0.0247 0.1042 0.1561
Loa Loa (eye worm) RNA binding protein 0.0128 0.0482 0.0717
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0092 0.0312 0.0458
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Brugia malayi prolyl oligopeptidase family protein 0.143 0.6597 1
Mycobacterium tuberculosis Conserved protein 0.0179 0.072 0.1323
Trypanosoma cruzi Aminopeptidase M1, putative 0.0036 0.0046 0.0087
Loa Loa (eye worm) hypothetical protein 0.0048 0.0104 0.0144
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0047 0.0307
Echinococcus multilocularis orexin receptor type 2 0.0029 0.0015 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine proteinase, putative 0.0182 0.0735 0.5918
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0358 0.0534
Plasmodium falciparum transporter, putative 0.004 0.0067 0.0776
Echinococcus multilocularis geminin 0.1194 0.549 0.8319
Loa Loa (eye worm) TAR-binding protein 0.0128 0.0482 0.0717
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0064 0.0081
Schistosoma mansoni bromodomain containing protein 0.0081 0.026 0.0255
Echinococcus multilocularis polycomb protein SCMH1 0.0255 0.1079 0.1623
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Loa Loa (eye worm) hypothetical protein 0.0154 0.0604 0.0902
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Schistosoma mansoni hypothetical protein 0.1194 0.549 0.5488
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.053 0.5809
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0015 0.0007
Echinococcus granulosus inhibitor of apoptosis protein 0.0527 0.2356 0.3561
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0985 0.4507 0.4504
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.004 0.0067 0.0091
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0067 0.0062
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0029 0.0015 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0736 0.1102
Echinococcus multilocularis GPCR, family 2 0.0032 0.0031 0.0031
Brugia malayi Dopamine receptor protein 1 0.0029 0.0015 0.0012
Loa Loa (eye worm) heterochromatin protein 1 0.0081 0.026 0.0381
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0527 0.2356 0.3565
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.0243 0.0353
Echinococcus granulosus beta LACTamase domain containing family member 0.0179 0.072 0.1077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0179 0.072 0.1323
Echinococcus multilocularis chromobox protein 1 0.0081 0.026 0.038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Schistosoma mansoni sex comb on midleg homolog 0.0255 0.1079 0.1075
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0188
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.017 0.0165
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0071 0.0212 0.2772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Plasmodium falciparum serine repeat antigen 3 0.0071 0.0212 0.2772
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0015 0.0007
Brugia malayi chromobox protein homolog 3 0.005 0.0116 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0071 0.0212 0.1374
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0154 0.0603 0.09
Loa Loa (eye worm) hypothetical protein 0.006 0.0161 0.023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.011 0.0106
Echinococcus multilocularis prolyl endopeptidase 0.0373 0.163 0.2459
Brugia malayi Muscleblind-like protein 0.0152 0.0594 0.089
Toxoplasma gondii cathepsin CPC2 0.0071 0.0212 0.0846
Echinococcus granulosus alpha 1A adrenergic receptor 0.0029 0.0015 0.0007
Entamoeba histolytica hypothetical protein 0.0071 0.0212 0.142
Brugia malayi Pre-SET motif family protein 0.0032 0.0029 0.0033
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0154 0.0603 0.4784
Brugia malayi hypothetical protein 0.004 0.0067 0.0091
Brugia malayi RNA recognition motif domain containing protein 0.0128 0.0482 0.072
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0071 0.0212 0.1374
Mycobacterium ulcerans hypothetical protein 0.0179 0.072 0.7977
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0154 0.0603 0.1325
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0737 0.3344 0.7416
Brugia malayi cathepsin Z-like cysteine proteinase 0.0071 0.0212 0.0311
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0064 0.0126
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0353 0.154 0.1536
Echinococcus multilocularis SAM and MBT domain containing protein 0.037 0.1617 0.2439
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Trichomonas vaginalis D-aminoacylase, putative 0.0179 0.072 0.4673
Plasmodium vivax unspecified product 0.0071 0.0212 0.2772
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Echinococcus multilocularis apoptotic protease activating factor 1 0.0154 0.0604 0.0901
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0051 0.0119 0.0248
Echinococcus multilocularis neuropeptide Y receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Echinococcus granulosus cathepsin L 0.0071 0.0212 0.0306
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0029 0.0015 0.0007
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0031 0.0033
Schistosoma mansoni alpha-glucosidase 0.0141 0.0544 0.0539
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0051 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Onchocerca volvulus 0.004 0.0067 0.0079
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0139 0.0531 0.416
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0049 0.011 0.0106
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0047 0.5
Echinococcus granulosus allatostatin A receptor 0.0029 0.0015 0.0007
Brugia malayi G-protein coupled receptor 0.0029 0.0015 0.0012
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0047 0.0307
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0182 0.0736 0.1103
Echinococcus multilocularis neuropeptide s receptor 0.0029 0.0015 0.0007
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.004 0.0067 0.0062
Schistosoma mansoni inhibitor of apoptosis protein 0.0527 0.2356 0.2353
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.143 0.6597 0.6596
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0049 0.011 0.0151
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Mycobacterium tuberculosis Probable esterase LipL 0.0179 0.072 0.1323
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0116 0.0752
Echinococcus multilocularis neuropeptide FF receptor 2 0.0029 0.0015 0.0007
Loa Loa (eye worm) transcription factor SMAD2 0.0353 0.1537 0.2319
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.004 0.0067 0.0086
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0212 0.0166
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0353 0.154 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0182 0.0735 0.11
Trypanosoma cruzi cysteine proteinase, putative 0.0071 0.0212 0.0454
Trichomonas vaginalis set domain proteins, putative 0.0247 0.1042 0.6767
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Onchocerca volvulus Deterin homolog 0.0527 0.2356 0.3557
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Trypanosoma cruzi target of rapamycin kinase 3 0.0126 0.0473 0.1036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0092 0.031 0.2013
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0067 0.0062
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0071 0.0212 0.2772
Loa Loa (eye worm) hypothetical protein 0.0092 0.0312 0.046
Echinococcus multilocularis calpain A 0.0056 0.0144 0.0203
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0029 0.0015 0.0012
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0051 0.0114
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0235 0.0984 0.098
Echinococcus granulosus peptide allatostatin:somatostatin 0.0029 0.0015 0.0007
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Schistosoma mansoni alpha-1 adrenergic receptor 0.0029 0.0015 0.001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Schistosoma mansoni biogenic amine receptor 0.0029 0.0015 0.001
Trypanosoma brucei glucosidase, putative 0.0036 0.0051 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Mycobacterium ulcerans lipase LipD 0.0179 0.072 0.7977
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0067 0.0436
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus multilocularis serotonin transporter 0.0235 0.0984 0.1478
Echinococcus granulosus cathepsin l1 0.0182 0.0735 0.11
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.143 0.6597 1
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0015 0.0007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0029 0.0015 0.0012
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Loa Loa (eye worm) MH2 domain-containing protein 0.0353 0.1537 0.2319
Brugia malayi CXXC zinc finger family protein 0.003 0.0019 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.143 0.6597 1
Plasmodium falciparum peptidase, putative 0.0139 0.0531 0.7176
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Schistosoma mansoni hypothetical protein 0.1194 0.549 0.5488
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0179 0.072 0.7977
Echinococcus granulosus SAM and MBT domain containing protein 0.037 0.1617 0.2439
Onchocerca volvulus 0.029 0.1242 0.1864
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Trichomonas vaginalis esterase, putative 0.0179 0.072 0.4673
Loa Loa (eye worm) prolyl oligopeptidase 0.0139 0.0531 0.0791
Toxoplasma gondii FATC domain-containing protein 0.0051 0.0119 0.0423
Onchocerca volvulus 0.0179 0.072 0.1071
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Echinococcus granulosus lysine specific demethylase 5A 0.0093 0.0317 0.0465
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0029 0.0015 0.001
Plasmodium vivax hypothetical protein, conserved 0.0139 0.0531 0.7176
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0071 0.0212 0.1374
Onchocerca volvulus Prolyl endopeptidase homolog 0.0373 0.163 0.2454
Echinococcus granulosus acylamino acid releasing enzyme 0.0139 0.0531 0.079
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Giardia lamblia Cathepsin B precursor 0.0353 0.154 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0051 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0015 0.001
Echinococcus granulosus fetal alzheimer antigen falz 0.004 0.0065 0.0083
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0212 0.1374
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0215 0.089 0.165
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Echinococcus multilocularis serotonin receptor 0.0029 0.0015 0.0007
Schistosoma mansoni opsin-like receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0139 0.0531 0.0791
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus granulosus tachykinin peptides receptor 99D 0.0029 0.0015 0.0007
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0029 0.0015 0.0008
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0071 0.0212 0.2772
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0071 0.0212 0.2772
Onchocerca volvulus 0.004 0.0067 0.0079
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0026 0.0002 0.0015
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.0001
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0051 0.0061
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0179 0.072 0.1583
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.0531 0.1163
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0651 0.0973
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.017 0.0487
Brugia malayi Pre-SET motif family protein 0.0217 0.0901 0.1357
Schistosoma mansoni caspase-7 (C14 family) 0.0154 0.0604 0.0599
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0071 0.0212 0.2772
Schistosoma mansoni hypothetical protein 0.0424 0.1872 0.1868
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Mycobacterium tuberculosis Probable hydrolase 0.0179 0.072 0.1323
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0527 0.2356 0.2353
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0029 0.0015 0.0008
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0047 0.001
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Plasmodium falciparum serine repeat antigen 7 0.0071 0.0212 0.2772
Echinococcus multilocularis g protein coupled receptor 0.0029 0.0015 0.0007
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0067 0.0086
Toxoplasma gondii preprocathepsin c precursor, putative 0.0071 0.0212 0.0846
Echinococcus granulosus cathepsin L 0.0071 0.0212 0.0306
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0064 0.0059
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0071 0.0212 0.2772
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0215 0.089 0.1963
Loa Loa (eye worm) hypothetical protein 0.0103 0.0364 0.0539
Echinococcus multilocularis neuropeptide receptor A26 0.0029 0.0015 0.0007
Brugia malayi hypothetical protein 0.0229 0.0957 0.1442
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0154 0.0603 0.1786
Echinococcus multilocularis inhibitor of apoptosis protein 0.0527 0.2356 0.3561
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0051 0.0061
Echinococcus granulosus cathepsin l1 0.0182 0.0735 0.11
Loa Loa (eye worm) hypothetical protein 0.0031 0.0024 0.0022
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0051 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0064 0.0151
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Echinococcus multilocularis cysteine protease 0.0182 0.0735 0.11
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0736 0.0732
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Entamoeba histolytica hypothetical protein 0.0051 0.0119 0.0621
Echinococcus multilocularis chromobox protein 1 0.0081 0.026 0.038
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0031 0.0031
Loa Loa (eye worm) melatonin receptor type 1A 0.0029 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Trypanosoma cruzi cysteine proteinase, putative 0.0071 0.0212 0.0454
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma brucei prolyl endopeptidase 0.0373 0.163 0.1591
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0054 0.0133 0.0128
Trypanosoma cruzi aminopeptidase, putative 0.0036 0.0046 0.0087
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0051 0.033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0212 0.1374
Echinococcus multilocularis cathepsin L cysteine protease 0.0182 0.0735 0.11
Brugia malayi Glycosyl hydrolases family 31 protein 0.0164 0.0651 0.0978
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Mycobacterium ulcerans esterase/lipase LipP 0.0179 0.072 0.7977
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0071 0.0212 0.2772
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0036 0.0049 0.0064
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0047 0.0007
Loa Loa (eye worm) hypothetical protein 0.0229 0.0957 0.1439
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.017 0.0165
Loa Loa (eye worm) hypothetical protein 0.0072 0.0217 0.0315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0252 0.1063 0.1599
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0383
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0527 0.2356 0.3565
Brugia malayi sulfakinin receptor protein 0.024 0.101 0.1521
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0364 0.036
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0056 0.0144 0.0203
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Echinococcus granulosus tumor suppressor p53 binding protein 1 0.0314 0.1357 0.2044
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.0046 0.0118
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0064 0.0416
Schistosoma mansoni histamine h1 receptor 0.0029 0.0015 0.001
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Trichomonas vaginalis chromobox protein, putative 0.0053 0.013 0.0843
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0215 0.089 1
Echinococcus multilocularis serotonin receptor 0.0029 0.0015 0.0007
Brugia malayi mbt repeat family protein 0.0439 0.1944 0.2939
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0215 0.089 0.1963
Brugia malayi larval opioid receptor 0.0029 0.0015 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.0066
Loa Loa (eye worm) hypothetical protein 0.0235 0.0984 0.1479
Echinococcus granulosus serotonin transporter 0.0235 0.0984 0.1478
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0029 0.0028
Echinococcus granulosus chromobox protein 1 0.0081 0.026 0.038
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0212 0.1374
Brugia malayi cathepsin L precursor 0.0071 0.0212 0.0311
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0015 0.001
Plasmodium vivax amine transporter, putative 0.004 0.0067 0.0776
Echinococcus granulosus fmrfamide receptor 0.0029 0.0015 0.0007
Brugia malayi calpain family protein 1 0.0054 0.0133 0.0191
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Schistosoma mansoni hypothetical protein 0.0154 0.0604 0.0599
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0015 0.0007
Brugia malayi cathepsin Z-like cysteine proteinase 0.0071 0.0212 0.0311
Onchocerca volvulus 0.003 0.0019 0.0007
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0015 0.0008
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.004 0.0067 0.5
Loa Loa (eye worm) hypothetical protein 0.0527 0.2356 0.3562
Schistosoma mansoni alpha glucosidase 0.0036 0.0051 0.0046
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0212 0.0454
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0064 0.0416
Echinococcus granulosus hypothetical protein 0.0029 0.0015 0.0007
Echinococcus multilocularis caspase 2 0.0154 0.0604 0.0901
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0099 0.0344 0.0506
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0182 0.0735 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0161 0.0617
Schistosoma mansoni survival motor neuron protein 0.0047 0.0099 0.0095
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0029 0.0015 0.0007
Plasmodium falciparum amino acid transporter, putative 0.004 0.0067 0.0776
Loa Loa (eye worm) solute carrier family 6 member 4 0.0235 0.0984 0.1479
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Entamoeba histolytica cysteine proteinase, putative 0.0182 0.0735 0.5918
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0499 0.2224 0.2187
Giardia lamblia Alanyl dipeptidyl peptidase 0.0139 0.0531 0.3162
Echinococcus granulosus zinc finger protein 0.0037 0.0051 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0031 0.0031
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0154 0.0603 0.1325
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0041 0.0075 0.007
Echinococcus granulosus neuropeptide receptor 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine proteinase 1, putative 0.0071 0.0212 0.142
Echinococcus multilocularis tar DNA binding protein 0.0128 0.0482 0.0715
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0067 0.0062
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0071 0.0212 0.2772
Echinococcus multilocularis cathepsin b 0.0985 0.4507 0.6826
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0029 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0188
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0207 0.0304
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0015 0.0007
Toxoplasma gondii hypothetical protein 0.004 0.0067 0.0188
Schistosoma mansoni alpha-glucosidase 0.0141 0.0544 0.0539
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0071 0.0212 0.0207
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0051 0.0119 0.0114
Echinococcus multilocularis tumor suppressor p53 binding protein 1 0.0314 0.1357 0.2044
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0015 0.001
Echinococcus granulosus cathepsin b 0.0985 0.4507 0.6826
Echinococcus granulosus G protein coupled receptor 139 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0343 0.2227
Brugia malayi Bromodomain containing protein 0.0039 0.0062 0.0084
Onchocerca volvulus 0.0071 0.0212 0.0299
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0736 0.0732
Entamoeba histolytica cysteine proteinase 2 0.0071 0.0212 0.142
Plasmodium falciparum serine repeat antigen 1 0.0071 0.0212 0.2772
Trypanosoma cruzi oligopeptidase b 0.0215 0.089 0.1963
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0139 0.0531 0.0486
Loa Loa (eye worm) ctsf protein 0.0182 0.0735 0.1102
Echinococcus multilocularis beta LACTamase domain containing family member 0.0179 0.072 0.1077
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Brugia malayi mbt repeat family protein 0.0266 0.1128 0.1701
Brugia malayi G-protein coupled receptor 0.0029 0.0015 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0071 0.0212 0.1374
Brugia malayi neuropeptide F receptor 0.0029 0.0015 0.0012
Onchocerca volvulus 0.0154 0.0604 0.0895
Trichomonas vaginalis penicillin-binding protein, putative 0.0179 0.072 0.4673
Plasmodium vivax SET domain protein, putative 0.0032 0.0029 0.0247
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0029 0.0015 0.001
Brugia malayi hypothetical protein 0.0037 0.0054 0.0072
Echinococcus granulosus biogenic amine 5HT receptor 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.0046 0.0301
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0139 0.0531 0.2297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Trichomonas vaginalis PIKK family atypical protein kinase 0.0154 0.0603 0.3917
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0071 0.0212 0.0207
Echinococcus multilocularis lysine specific demethylase 5A 0.0074 0.023 0.0333
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.004 0.0067 0.0086
Loa Loa (eye worm) hypothetical protein 0.0737 0.3344 0.5061
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0373 0.163 0.4864
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Loa Loa (eye worm) hypothetical protein 0.0235 0.0984 0.1479
Schistosoma mansoni hypothetical protein 0.0824 0.3752 0.3749
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0985 0.4507 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Brugia malayi cathepsin L-like precursor 0.0182 0.0735 0.1105
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.121 1
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0034 0.0037 0.0042
Echinococcus granulosus apoptotic protease activating factor 1 0.0154 0.0604 0.0901
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0071 0.0212 0.2772
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0047 0.0056
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.0675 0.305 0.4614
Trypanosoma brucei oligopeptidase b 0.0215 0.089 0.0848
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Trichomonas vaginalis conserved hypothetical protein 0.005 0.0116 0.0752
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0029 0.0015 0.0007
Echinococcus granulosus uncharacterized sodium dependent transporter 0.004 0.0067 0.0086
Loa Loa (eye worm) hypothetical protein 0.0036 0.0049 0.006
Loa Loa (eye worm) hypothetical protein 0.004 0.0068 0.0089
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0182 0.0735 0.1618
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0071 0.0212 0.142
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Onchocerca volvulus 0.0182 0.0735 0.1094
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) cathepsin B 0.0353 0.154 0.2323
Leishmania major hypothetical protein, conserved 0.0179 0.072 0.2135
Schistosoma mansoni cathepsin F (C01 family) 0.0182 0.0735 0.0731
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0154 0.0603 0.0905
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Trypanosoma cruzi oligopeptidase b 0.0215 0.089 0.1963
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0499 0.2224 0.6643
Schistosoma mansoni hypothetical protein 0.0314 0.1357 0.1353
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0036 0.0049 0.0058
Loa Loa (eye worm) calpain family protein 1 0.0054 0.0133 0.0187
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0182 0.0735 0.4774
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0113 0.0412 0.0609
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0499 0.2224 1
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0517
Trichomonas vaginalis D-aminoacylase, putative 0.0179 0.072 0.4673
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.031 0.201
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0036 0.0049 0.0092
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.053 0.5726
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0373 0.163 0.1626
Onchocerca volvulus 0.0179 0.072 0.1071
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0139 0.0531 0.416
Plasmodium vivax hypothetical protein, conserved 0.004 0.0067 0.0776
Plasmodium falciparum serine repeat antigen 5 0.0071 0.0212 0.2772
Echinococcus multilocularis g-protein coupled receptor 0.0029 0.0015 0.0007
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.053 0.0958
Trichomonas vaginalis chromobox protein, putative 0.0053 0.013 0.0843
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0049 0.0317
Brugia malayi TAR-binding protein 0.0128 0.0482 0.072
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Onchocerca volvulus 0.0182 0.0735 0.1094
Brugia malayi Heterochromatin protein 1 0.0081 0.026 0.0385
Echinococcus granulosus serine protein kinase ATM 0.0051 0.0119 0.0164
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0071 0.0212 0.0207
Brugia malayi G protein-coupled receptor F59B2.13 0.0029 0.0015 0.0012
Onchocerca volvulus 0.0103 0.0364 0.0531
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0154 0.0603 0.4784
Loa Loa (eye worm) hypothetical protein 0.0373 0.163 0.246
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Onchocerca volvulus 0.0182 0.0735 0.1094
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.0068
Loa Loa (eye worm) hypothetical protein 0.0152 0.0594 0.0887
Brugia malayi RNA binding protein 0.0128 0.0482 0.072
Leishmania major C-8 sterol isomerase-like protein 0.0737 0.3344 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0056 0.0144 0.014
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0212 0.1
Loa Loa (eye worm) hypothetical protein 0.0028 0.001 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0015 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0029 0.0015 0.001
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0053 0.013 0.0175
Toxoplasma gondii prolyl endopeptidase 0.0373 0.163 0.73
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0029 0.0015 0.0008
Brugia malayi Bromodomain containing protein 0.0093 0.0316 0.0469
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0212 0.1
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0041 0.0072 0.0094
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.012
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0126 0.0473 0.0429
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0019 0.0015
Onchocerca volvulus 0.0036 0.0046 0.0048
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Giardia lamblia Alanyl dipeptidyl peptidase 0.0139 0.0531 0.3162
Entamoeba histolytica hypothetical protein, conserved 0.0139 0.0531 0.416
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0501 0.2233 0.3374
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Plasmodium vivax unspecified product 0.0071 0.0212 0.2772
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.002 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0099 0.014
Echinococcus granulosus histone acetyltransferase MYST2 0.0092 0.0312 0.0458
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0015 0.0008
Echinococcus granulosus cathepsin b 0.0985 0.4507 0.6826
Brugia malayi Serotonin receptor 0.0029 0.0015 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0029 0.0015 0.001
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.0089
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Loa Loa (eye worm) inositol-1 0.0036 0.0047 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0071 0.0212 0.1374
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0179 0.072 0.1323
Echinococcus multilocularis tumor protein p63 0.0705 0.3191 0.4828
Entamoeba histolytica protein kinase rad3, putative 0.0036 0.0049 0.002
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0099 0.0343 0.2227
Echinococcus granulosus prolyl endopeptidase 0.0373 0.163 0.2459
Trypanosoma cruzi prolyl endopeptidase 0.0373 0.163 0.3607
Loa Loa (eye worm) mbt repeat family protein 0.0266 0.1128 0.1698
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0031 0.0037
Loa Loa (eye worm) hypothetical protein 0.0102 0.0358 0.053
Schistosoma mansoni opsin-like receptor 0.0029 0.0015 0.001
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0358 0.053
Entamoeba histolytica cysteine proteinase, putative 0.0182 0.0735 0.5918
Entamoeba histolytica cysteine protease, putative 0.0182 0.0735 0.5918
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Schistosoma mansoni amine GPCR 0.0029 0.0015 0.001
Loa Loa (eye worm) norepinephrine transporter 0.0235 0.0984 0.1479
Echinococcus granulosus microtubule associated protein 2 0.0675 0.305 0.4614
Echinococcus granulosus tumor protein p63 0.0705 0.3191 0.4828
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0099 0.0344 0.0506
Echinococcus granulosus histone lysine methyltransferase setb 0.0049 0.011 0.0151
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Schistosoma mansoni hypothetical protein 0.0037 0.0054 0.0049
Toxoplasma gondii cathepsin CPC1 0.0071 0.0212 0.0846
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0154 0.0603 0.09
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0234 0.0979 0.182
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0064 0.018 0.0134
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0439 0.1944 0.293
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0067 0.0086
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0071 0.0212 0.0207
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Trypanosoma brucei C-8 sterol isomerase, putative 0.0737 0.3344 0.3313
Schistosoma mansoni adenoreceptor 0.0029 0.0015 0.001
Mycobacterium leprae conserved hypothetical protein 0.0179 0.072 0.8016
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0215 0.089 1
Brugia malayi Papain family cysteine protease containing protein 0.0182 0.0735 0.1105
Schistosoma mansoni cathepsin S (C01 family) 0.0071 0.0212 0.0207
Brugia malayi calpain family protein 1 0.0054 0.0133 0.0191
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Echinococcus granulosus neuropeptide receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0499 0.2224 0.4926
Loa Loa (eye worm) hypothetical protein 0.0182 0.0735 0.1102
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Plasmodium falciparum cysteine proteinase falcipain 3 0.0182 0.0735 1
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0071 0.0212 0.2772
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0182 0.0736 0.1106
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0051 0.0063
Onchocerca volvulus Heterochromatin protein 1 homolog 0.005 0.0116 0.0154
Onchocerca volvulus 0.0182 0.0735 0.1094
Echinococcus multilocularis cathepsin L cysteine protease 0.0182 0.0735 0.11
Echinococcus multilocularis sodium and chloride dependent glycine 0.004 0.0067 0.0086
Brugia malayi prolyl oligopeptidase family protein 0.0139 0.0531 0.0795
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.0957 0.1437
Brugia malayi G protein-coupled receptor 0.0029 0.0015 0.0012
Brugia malayi cathepsin F-like cysteine proteinase 0.0071 0.0212 0.0311
Schistosoma mansoni cpg binding protein 0.003 0.0019 0.0015
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Plasmodium vivax serine-repeat antigen (SERA) 0.0071 0.0212 0.2772
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0087
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0188
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0071 0.0212 0.2772
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0179 0.072 0.0715
Entamoeba histolytica prolyl oligopeptidase family protein 0.0139 0.0531 0.416
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0527 0.2356 0.3561
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0736 0.1102
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0031 0.0031
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Onchocerca volvulus 0.0182 0.0735 0.1094
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0029 0.0015 0.001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0049 0.0317
Schistosoma mansoni chromobox protein 0.0201 0.0823 0.0819
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0071 0.0212 0.0311
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0071 0.0212 0.1
Brugia malayi prolyl oligopeptidase family protein 0.0499 0.2224 0.3364
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0036 0.0046 0.0042
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0071 0.0212 0.142
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0215 0.089 0.2647
Schistosoma mansoni cpg binding protein 0.0048 0.0107 0.0102
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0015 0.0007
Schistosoma mansoni tar DNA-binding protein 0.0128 0.0482 0.0477
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0309 0.2007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0029 0.0015 0.0012
Echinococcus multilocularis calpain family protein 1, d 0.004 0.0066 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Brugia malayi Inositol-1 0.0036 0.0047 0.0061
Brugia malayi FAT domain containing protein 0.0028 0.001 0.0005
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0064 0.0081
Schistosoma mansoni myelin transcription factor 1 myt1 0.0092 0.0312 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Giardia lamblia Cysteine protease 0.0071 0.0212 0.1
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0041 0.0072 0.0094
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.004 0.0067 0.0086
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Brugia malayi Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0091
Plasmodium falciparum serine repeat antigen 8 0.0071 0.0212 0.2772
Schistosoma mansoni cpg binding protein 0.0048 0.0107 0.0102
Echinococcus multilocularis G protein coupled receptor 139 0.0029 0.0015 0.0007
Onchocerca volvulus Cathepsin F homolog 0.0182 0.0735 0.1094
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0036 0.0049 0.0058
Brugia malayi prolyl oligopeptidase family protein 0.0139 0.0531 0.0795
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Schistosoma mansoni inositol monophosphatase 0.0036 0.0047 0.0043
Trichomonas vaginalis chromobox protein, putative 0.0081 0.026 0.1691
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0071 0.0212 0.0207
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.004 0.0067 0.0087
Echinococcus multilocularis fmrfamide receptor 0.0029 0.0015 0.0007
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0071 0.0212 0.2772
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Brugia malayi RE15519p 0.0029 0.0015 0.0012
Echinococcus multilocularis muscleblind protein 1 0.0152 0.0594 0.0886
Echinococcus multilocularis acylamino acid releasing enzyme 0.0139 0.0531 0.079
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus cysteine protease 0.0071 0.0212 0.0306
Schistosoma mansoni hypothetical protein 0.007 0.0207 0.0202
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Echinococcus granulosus 7TM GPCR rhodopsin 0.0029 0.0015 0.0007
Plasmodium falciparum serine repeat antigen 6 0.0071 0.0212 0.2772
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Entamoeba histolytica hypothetical protein 0.0037 0.0054 0.0066
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0051 0.0062
Trypanosoma cruzi major cysteine proteinase, putative 0.0071 0.0212 0.0454
Loa Loa (eye worm) hypothetical protein 0.005 0.0116 0.0162
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0068 0.0198 0.0152
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0064 0.0087
Loa Loa (eye worm) phosphatidylinositol 3 0.0154 0.0603 0.0901
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Schistosoma mansoni hypothetical protein 0.0527 0.2356 0.2353
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Schistosoma mansoni biogenic amine (5HT) receptor 0.0029 0.0015 0.001
Echinococcus granulosus tar DNA binding protein 0.0128 0.0482 0.0715
Schistosoma mansoni hypothetical protein 0.0047 0.0099 0.0095
Echinococcus granulosus neuropeptide FF receptor 2 0.0029 0.0015 0.0007
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0015 0.0007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0047 0.0056
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0179 0.072 0.1078
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0182 0.0735 1
Schistosoma mansoni zinc finger protein 0.0037 0.0051 0.0046
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.0957 0.1437
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0154 0.0603 0.0559
Schistosoma mansoni neuropeptide receptor 0.0029 0.0015 0.001
Brugia malayi cathepsin B-like cysteine proteinase 0.0985 0.4507 0.6827
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0029 0.0024
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0212 0.0307
Trypanosoma brucei prolyl oligopeptidase, putative 0.0215 0.089 0.0848
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0064 0.0059
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0824 0.3752 0.568
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0071 0.0212 0.0307
Loa Loa (eye worm) calpain family protein 1 0.004 0.0066 0.0086
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0047 0.0307
Loa Loa (eye worm) neuropeptide F receptor 0.0029 0.0015 0.0008
Schistosoma mansoni cathepsin B (C01 family) 0.0071 0.0212 0.0207
Echinococcus multilocularis cathepsin L 0.0071 0.0212 0.0306
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Echinococcus granulosus caspase 2 0.0154 0.0604 0.0901
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0309 0.2007
Brugia malayi follicle stimulating hormone receptor 0.0252 0.1063 0.1603
Leishmania major phosphatidylinositol 3-kinase, putative 0.0064 0.018 0.0517
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0051 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0103 0.0361 0.2346
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0071 0.0212 0.0307
Onchocerca volvulus Cathepsin L homolog 0.0071 0.0212 0.0299
Brugia malayi Dopamine receptor 0.0029 0.0015 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0119 0.044 0.2857
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Echinococcus granulosus cathepsin L cysteine protease 0.0071 0.0212 0.0306
Toxoplasma gondii target of rapamycin (TOR), putative 0.0119 0.044 0.1885
Brugia malayi GnHR receptor homolog 0.0029 0.0015 0.0012
Onchocerca volvulus Cathepsin L homolog 0.0182 0.0735 0.1094
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.017 0.0242
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) prolyl oligopeptidase 0.143 0.6597 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0064 0.0083
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Brugia malayi Peptidase family M1 containing protein 0.0036 0.0046 0.006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Echinococcus multilocularis histone acetyltransferase myst3 0.0043 0.0081 0.0107
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0029 0.0015 0.0012
Schistosoma mansoni sodium/chloride dependent transporter 0.004 0.0067 0.0062
Brugia malayi Dopamine receptor protein 2 0.0029 0.0015 0.0012
Mycobacterium tuberculosis Probable lipase LipE 0.0179 0.072 0.1323
Schistosoma mansoni hypothetical protein 0.0029 0.0015 0.001
Echinococcus granulosus cpg binding protein 0.0048 0.0107 0.0146
Echinococcus granulosus sex peptide receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) CHromoDomain protein family member 0.0041 0.0072 0.0096
Giardia lamblia Cathepsin L-like protease 0.0071 0.0212 0.1
Loa Loa (eye worm) aminopeptidase N 0.0036 0.0046 0.0056
Plasmodium falciparum serine repeat antigen 9 0.0071 0.0212 0.2772
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0039 0.0061 0.012
Brugia malayi hypothetical protein 0.024 0.101 0.1521
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.004 0.0065 0.0061
Schistosoma mansoni sex comb on midleg homolog 0.0255 0.1079 0.1075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Brugia malayi cathepsin L-like cysteine proteinase 0.0071 0.0212 0.0311
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0068 0.0442
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0029 0.0015 0.0007
Echinococcus granulosus sodium and chloride dependent glycine 0.004 0.0067 0.0086
Echinococcus granulosus neuropeptide s receptor 0.0029 0.0015 0.0007
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0051 0.0119 0.0073
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0182 0.0736 0.1102
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0071 0.0212 0.0207
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0071 0.0212 0.1
Brugia malayi jmjC domain containing protein 0.0135 0.0515 0.0771
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Trichomonas vaginalis chromobox protein, putative 0.0081 0.026 0.1691
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus dnaJ subfamily B 0.0424 0.1872 0.2826
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0029 0.0015 0.001
Mycobacterium tuberculosis Conserved protein 0.0179 0.072 0.1323
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0029 0.0015 0.0007
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0064 0.0081
Brugia malayi prolyl oligopeptidase family protein 0.0373 0.163 0.2463
Loa Loa (eye worm) hypothetical protein 0.0054 0.0133 0.0187
Brugia malayi Melatonin receptor type 1A 0.0029 0.0015 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0139 0.0531 0.3446
Echinococcus granulosus rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0029 0.0015 0.0007
Onchocerca volvulus Cell death protein 3 homolog 0.0154 0.0604 0.0895
Schistosoma mansoni hypothetical protein 0.0032 0.0031 0.0026
Onchocerca volvulus 0.0179 0.072 0.1071
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0283 0.121 1
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.0046 0.0301
Loa Loa (eye worm) hypothetical protein 0.0527 0.2356 0.3562
Echinococcus multilocularis rhodopsin orphan GPCR 0.0029 0.0015 0.0007
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0056 0.0144 0.014
Loa Loa (eye worm) hypothetical protein 0.0049 0.011 0.0153
Loa Loa (eye worm) hypothetical protein 0.0154 0.0604 0.0902
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Loa Loa (eye worm) hypothetical protein 0.0039 0.0063 0.0081
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.143 0.6597 1
Brugia malayi CHD4 protein 0.0041 0.0072 0.01
Giardia lamblia GTOR 0.0154 0.0603 0.3653
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0092 0.0312 0.0463
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0472 0.3068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0039 0.0061 0.0078
Echinococcus granulosus chromobox protein 2 0.0201 0.0823 0.1234
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Echinococcus granulosus dro:myosuppressin receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0985 0.4507 0.6826
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0064 0.0081
Toxoplasma gondii cathepsin CPL 0.0182 0.0735 0.3228
Onchocerca volvulus 0.0047 0.0099 0.0128
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0071 0.0212 0.0207
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0179 0.072 0.0715
Echinococcus granulosus neuropeptide Y receptor 0.0029 0.0015 0.0007
Trypanosoma cruzi cruzipain precursor, putative 0.0182 0.0735 0.1618
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0002 0.0015
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0064 0.018 0.0257
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0051 0.033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni neuropeptide F-like receptor 0.0029 0.0015 0.001
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0067 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0051 0.0119 0.0771
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0042 0.0075 0.0226
Onchocerca volvulus 0.0182 0.0735 0.1094
Trypanosoma cruzi hypothetical protein, conserved 0.0139 0.0531 0.1163
Echinococcus granulosus g protein coupled receptor 0.0029 0.0015 0.0007
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0499 0.2224 0.2187
Brugia malayi Subtilase family protein 0.0264 0.1119 0.1687
Giardia lamblia Encystation-specific protease 0.0071 0.0212 0.1
Loa Loa (eye worm) hypothetical protein 0.0179 0.072 0.1078
Toxoplasma gondii ABC1 family protein 0.0179 0.072 0.3157
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0383
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus granulosus histone acetyltransferase myst3 0.0043 0.0081 0.0107
Giardia lamblia Cathepsin B precursor 0.0071 0.0212 0.1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0182 0.0735 0.4774
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0064 0.018 0.0175
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0015 0.0007
Schistosoma mansoni opsin-like receptor 0.0029 0.0015 0.001
Plasmodium falciparum serine repeat antigen 2 0.0071 0.0212 0.2772
Schistosoma mansoni chromobox protein 0.0081 0.026 0.0256
Onchocerca volvulus 0.0182 0.0735 0.1094
Echinococcus multilocularis cpg binding protein 0.0048 0.0107 0.0146
Trypanosoma cruzi hypothetical protein, conserved 0.0179 0.072 0.1583
Onchocerca volvulus 0.0182 0.0735 0.1094
Mycobacterium tuberculosis Conserved protein 0.0179 0.072 0.1323
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0128 0.0482 0.0717
Brugia malayi Tachykinin-like peptides receptor 99D 0.0029 0.0015 0.0012
Onchocerca volvulus 0.0036 0.0046 0.0048
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0054 0.0134 0.013
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0139 0.0531 0.0526
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0182 0.0735 0.4774
Loa Loa (eye worm) hypothetical protein 0.0139 0.0531 0.0791
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0235 0.0984 0.1483
Plasmodium vivax vivapain-3 0.0071 0.0212 0.2772
Brugia malayi MH2 domain containing protein 0.0353 0.1537 0.2322
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0051 0.0038
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1142 0.5246 1
Loa Loa (eye worm) fibroinase 0.0182 0.0735 0.1102
Leishmania major cathepsin L-like protease 0.0182 0.0735 0.2182
Trichomonas vaginalis D-aminoacylase, putative 0.0179 0.072 0.4673
Plasmodium vivax vivapain-2 0.0182 0.0735 1
Brugia malayi Serotonin receptor 0.0029 0.0015 0.0012
Echinococcus granulosus somatostatin receptor 0.0029 0.0015 0.0007
Echinococcus granulosus serotonin receptor 0.0029 0.0015 0.0007
Brugia malayi hypothetical protein 0.0154 0.0604 0.0906
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0071 0.0212 0.1374
Brugia malayi hypothetical protein 0.0029 0.0015 0.0012
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0068 0.0199 0.0153
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0051 0.033
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Onchocerca volvulus Cathepsin L homolog 0.0182 0.0735 0.1094
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.004 0.0067 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0092 0.0312 0.0458
Echinococcus granulosus g protein coupled receptor 0.0029 0.0015 0.0007
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Schistosoma mansoni jumonji/arid domain-containing protein 0.0093 0.0317 0.0312
Echinococcus multilocularis chromobox protein 2 0.0201 0.0823 0.1234
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0051 0.0119 0.017
Toxoplasma gondii cathepsin B 0.0353 0.154 0.6889
Echinococcus multilocularis cathepsin L 0.0071 0.0212 0.0306
Echinococcus multilocularis neuropeptides capa receptor 0.0029 0.0015 0.0007
Echinococcus multilocularis cysteine protease 0.0182 0.0735 0.11
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0017 0.011
Echinococcus granulosus geminin 0.1194 0.549 0.8319
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0737 0.3344 0.5063
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0071 0.0212 0.2772
Echinococcus multilocularis neuropeptide receptor 0.0029 0.0015 0.0007
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.031 0.201
Entamoeba histolytica cysteine protease, putative 0.0071 0.0212 0.142
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.017 0.0242
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0064 0.018 0.0134
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0064 0.0018
Echinococcus granulosus neuropeptide receptor A26 0.0029 0.0015 0.0007
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Schistosoma mansoni neuropeptide f receptor 76f 0.0029 0.0015 0.001
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.017 0.0656
Echinococcus granulosus orexin receptor type 2 0.0029 0.0015 0.0007
Loa Loa (eye worm) TYRA-2 protein 0.0029 0.0015 0.0008
Schistosoma mansoni fkbp-rapamycin associated protein 0.0036 0.0049 0.0044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0098 0.0342 0.2221
Entamoeba histolytica prolyl oligopeptidase family protein 0.0139 0.0531 0.416
Brugia malayi neuropeptide F receptor 0.0029 0.0015 0.0012
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0113 0.0412 0.0609
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0046 0.0055
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0217 0.0901 0.1354
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0071 0.0212 0.0207
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0029 0.0017 0.011
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0499 0.2224 0.4926
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Loa Loa (eye worm) serotonin transporter b 0.0235 0.0984 0.1479
Brugia malayi beta-lactamase 0.0179 0.072 0.1081
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.0046 0.0118
Schistosoma mansoni phd finger protein 0.0043 0.0081 0.0076
Toxoplasma gondii hypothetical protein 0.0139 0.0531 0.2297
Giardia lamblia Hypothetical protein 0.0071 0.0212 0.1
Trypanosoma cruzi cysteine peptidase, putative 0.0182 0.0735 0.1618
Entamoeba histolytica prolyl oligopeptidase family protein 0.0139 0.0531 0.416
Trichomonas vaginalis PIKK family atypical protein kinase 0.0064 0.018 0.1167
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0264 0.1119 0.1115
Brugia malayi hypothetical protein 0.0036 0.0046 0.006
Echinococcus multilocularis G-protein coupled receptor, putative 0.0029 0.0015 0.0007
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0036 0.0046 0.0055
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0047 0.0089
Toxoplasma gondii non-specific serine/threonine protein kinase 0.004 0.0068 0.0193
Plasmodium vivax hypothetical protein, conserved 0.0179 0.072 0.9785
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.001 0.0066
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0051 0.033
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.0243 0.0353
Plasmodium falciparum cysteine proteinase falcipain 1 0.0071 0.0212 0.2772
Brugia malayi Cathepsin L-like precursor 0.0182 0.0735 0.1105
Echinococcus granulosus 7tm_1 domain containing protein 0.0029 0.0015 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0182 0.0736 0.1102
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.031 0.201
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0054 0.0066
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0029 0.0015 0.0007
Loa Loa (eye worm) phosphatidylinositol 3 0.0064 0.018 0.0258
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0064 0.0081
Brugia malayi PHD-finger family protein 0.0042 0.0077 0.0106
Schistosoma mansoni inositol monophosphatase 0.0036 0.0047 0.0043
Schistosoma mansoni sodium-dependent amino acid transporter 0.004 0.0067 0.0062
Brugia malayi Cell death protein 3 precursor 0.0154 0.0604 0.0906
Onchocerca volvulus 0.0235 0.0984 0.1472
Echinococcus granulosus Dipeptidyl peptidase 9 0.0499 0.2224 0.336
Brugia malayi beta-lactamase family protein 0.0179 0.072 0.1081
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0358 0.0534
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0182 0.0735 0.0692
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Brugia malayi beta-lactamase family protein 0.0179 0.072 0.1081
Echinococcus granulosus neuropeptides capa receptor 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.024 0.101 0.1518
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0071 0.0212 0.1374
Loa Loa (eye worm) G-protein coupled receptor 0.0029 0.0015 0.0008
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0179 0.072 0.1081
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0071 0.0212 0.0166
Schistosoma mansoni hypothetical protein 0.0028 0.001 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0091 0.0309 0.2007
Loa Loa (eye worm) hypothetical protein 0.004 0.0066 0.0086
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0071 0.0212 0.0454
Echinococcus multilocularis lysosomal alpha glucosidase 0.0164 0.0651 0.0973
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0051 0.033
Schistosoma mansoni cathepsin F (C01 family) 0.0182 0.0735 0.0731
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.017 0.1463
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0071 0.0212 0.1374
Loa Loa (eye worm) beta-lactamase 0.0179 0.072 0.1078
Loa Loa (eye worm) subtilase 0.0264 0.1119 0.1684
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0527 0.2356 0.3561
Trichomonas vaginalis PIKK family atypical protein kinase 0.0154 0.0603 0.3917
Echinococcus granulosus polycomb protein SCMH1 0.0255 0.1079 0.1623
Trichomonas vaginalis PIKK family atypical protein kinase 0.0126 0.0473 0.307
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0182 0.0736 0.0732
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0373 0.163 0.1626
Trypanosoma brucei hypothetical protein, conserved 0.0179 0.072 0.0676
Brugia malayi Papain family cysteine protease containing protein 0.0071 0.0212 0.0311
Echinococcus granulosus g protein coupled receptor 0.0029 0.0015 0.0007
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0499 0.2224 0.222
Loa Loa (eye worm) hypothetical protein 0.004 0.0067 0.0087
Loa Loa (eye worm) cysteine protease 0.0182 0.0735 0.1102
Treponema pallidum fructose-bisphosphate aldolase 0.0283 0.121 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0029 0.0015 0.001
Entamoeba histolytica cysteine proteinase, putative 0.0071 0.0212 0.142
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.004 0.0067 0.0062
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.004 0.0067 0.0062
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0182 0.0735 0.1102
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0501 0.2233 0.3374
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.004 0.0067 0.0086
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.037 0.1617 0.1613
Loa Loa (eye worm) hypothetical protein 0.0377 0.165 0.2491
Mycobacterium tuberculosis Probable lipase LipD 0.0179 0.072 0.1323
Echinococcus multilocularis fetal alzheimer antigen, falz 0.004 0.0065 0.0083
Echinococcus multilocularis muscleblind protein 0.0152 0.0594 0.0886
Plasmodium vivax serine-repeat antigen (SERA) 0.0071 0.0212 0.2772
Plasmodium vivax vivapain-1 0.0071 0.0212 0.2772
Trypanosoma brucei cysteine peptidase C (CPC) 0.0353 0.154 0.15
Giardia lamblia Fructose-bisphosphate aldolase 0.0283 0.121 0.7766
Echinococcus granulosus g-protein coupled receptor 0.0029 0.0015 0.0007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0029 0.0015 0.0007
Loa Loa (eye worm) hypothetical protein 0.0029 0.0015 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0071 0.0212 0.0454
Schistosoma mansoni chromobox protein 0.0081 0.026 0.0256
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0283 0.121 0.7859
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0047 0.0098
Schistosoma mansoni biogenic amine receptor 0.0029 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0439 0.1944 0.2936
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0064 0.0081
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0154 0.0603 0.0559
Schistosoma mansoni cathepsin C 0.0071 0.0212 0.0207
Echinococcus granulosus calpain A 0.0056 0.0144 0.0203
Echinococcus multilocularis serine protein kinase ATM 0.0051 0.0119 0.0164
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0064 0.0416
Echinococcus granulosus tm gpcr rhodopsin 0.0029 0.0015 0.0007
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0215 0.089 0.0848
Echinococcus granulosus aminopeptidase N 0.0036 0.0046 0.0055
Loa Loa (eye worm) hypothetical protein 0.0235 0.0984 0.1479
Schistosoma mansoni biogenic amine receptor 0.0029 0.0015 0.001
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.017 0.0269
Loa Loa (eye worm) hypothetical protein 0.0071 0.0212 0.0307
Giardia lamblia Cathepsin L precursor 0.0071 0.0212 0.1
Giardia lamblia Cathepsin L-like protease 0.0071 0.0212 0.1
Echinococcus multilocularis allatostatin A receptor 0.0029 0.0015 0.0007

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 3.5481 uM PubChem BioAssay. qHTS of GLP-1 Receptor Inverse Agonists (Inhibition Mode). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 11.6891 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 100 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.