Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2008 | 0.2157 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.6941 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.6941 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.5021 | 0.6114 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.2008 | 0.2157 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0004 | 0 | 0.5 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.2008 | 0.1604 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.6941 | 0.8985 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.7617 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.2008 | 0.1579 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.6941 | 0.6941 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.0484 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2008 | 0.2008 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.7617 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0005 | 0.0127 | 0.0127 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.7617 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.6941 | 0.6941 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.7617 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2008 | 0.2157 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.6941 | 0.8988 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.6941 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.6941 | 0.6941 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.2008 | 0.1604 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.4403 | 0.519 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.6941 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.2008 | 0.1579 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2008 | 0.2008 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0651 | 0.0651 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.4403 | 0.5175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Plasmodium falciparum | zinc finger protein, putative | 0.0004 | 0 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4403 | 0.4403 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.5021 | 0.5021 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.2008 | 0.2157 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.4688 | 0.6418 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0542 | 1 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.4688 | 0.6418 |
Onchocerca volvulus | 0.0031 | 0.4403 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2008 | 0.2008 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.2008 | 0.2157 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.2008 | 0.2008 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0956 | 0.0484 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0542 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0542 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.4688 | 0.4688 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.2008 | 0.2157 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.006 | 0.8869 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.5021 | 0.6102 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.