Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.6823 | 0.6823 |
Brugia malayi | Cytochrome P450 family protein | 0.0027 | 0.2445 | 0.2445 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0027 | 0.2445 | 0.2445 |
Leishmania major | basic transcription factor 3a, putative | 0.0034 | 0.3842 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.0064 | 1 | 1 |
Toxoplasma gondii | NAC domain-containing protein | 0.0034 | 0.3842 | 0.5 |
Brugia malayi | Peroxidasin | 0.0064 | 1 | 1 |
Brugia malayi | beta-NAC-like protein | 0.0034 | 0.3842 | 0.3842 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0064 | 1 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0027 | 0.2445 | 0.2445 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.3665 | 0.3665 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.3665 | 0.3665 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0064 | 1 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.6823 | 0.6823 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0034 | 0.3842 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0034 | 0.3842 | 0.5 |
Echinococcus multilocularis | peroxidasin | 0.0064 | 1 | 1 |
Echinococcus granulosus | transcription factor btf3 | 0.0034 | 0.3842 | 0.3842 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 1 | 1 |
Brugia malayi | Blistered cuticle protein 3 | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Onchocerca volvulus | Peroxidase homolog | 0.0064 | 1 | 0.5 |
Onchocerca volvulus | 0.0064 | 1 | 0.5 | |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0034 | 0.3842 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0034 | 0.3842 | 0.5 |
Echinococcus granulosus | peroxidasin | 0.0064 | 1 | 1 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.3842 | 1 |
Schistosoma mansoni | transcription factor btf3 | 0.0034 | 0.3842 | 0.3842 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.3842 | 0.5 |
Schistosoma mansoni | peroxidasin | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 1 | 1 |
Echinococcus multilocularis | transcription factor btf3 | 0.0034 | 0.3842 | 0.3842 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0027 | 0.2445 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0064 | 1 | 0.5 |
Onchocerca volvulus | 0.0064 | 1 | 0.5 | |
Onchocerca volvulus | 0.0064 | 1 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.6823 | 0.6823 |
Loa Loa (eye worm) | ICD-1 protein | 0.0034 | 0.3842 | 0.3842 |
Onchocerca volvulus | Dual oxidase homolog | 0.0064 | 1 | 0.5 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0034 | 0.3842 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.3842 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.3665 | 0.3665 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.0064 | 1 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.6823 | 0.6823 |
Brugia malayi | Cytochrome P450 family protein | 0.0027 | 0.2445 | 0.2445 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0027 | 0.2445 | 0.2445 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.3842 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0833 | 0.0833 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0034 | 0.3842 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.