Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0227 | 1 | 1 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0118 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1104 | 0.1104 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0059 | 0.1988 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0059 | 0.1988 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.2155 | 1 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.038 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.038 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0118 | 0.0546 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0256 | 0.1188 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0256 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.2501 | 0.2501 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.038 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0256 | 0.1287 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.038 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.088 | 0.4427 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.1193 | 0.1193 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.038 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0167 | 0.0774 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.088 | 0.4427 |
Brugia malayi | Bromodomain containing protein | 0.0074 | 0.2701 | 0.2423 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0994 | 0.0994 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.038 | 0.5 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0118 | 0.0592 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.038 | 0.5 |
Brugia malayi | hypothetical protein | 0.0025 | 0.038 | 0.0014 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.038 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0167 | 0.0167 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.038 | 0.038 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.099 | 0.0648 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0029 | 0.0029 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.