Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0134 | 0.2948 | 0.2948 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.5175 | 0.5175 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0098 | 0.1905 | 0.1905 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.058 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.1905 | 0.1905 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0134 | 0.2948 | 0.2948 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0032 | 0 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.058 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.1905 | 0.1905 |
Echinococcus granulosus | tar DNA binding protein | 0.0378 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0308 | 0.7992 | 0.7992 |
Schistosoma mansoni | tar DNA-binding protein | 0.0378 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.058 | 0.058 |
Echinococcus multilocularis | tar DNA binding protein | 0.0378 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0378 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0211 | 0.5175 | 0.5175 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0378 | 1 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0098 | 0.1905 | 0.1905 |
Echinococcus multilocularis | GPCR, family 2 | 0.0098 | 0.1905 | 0.1905 |
Schistosoma mansoni | tar DNA-binding protein | 0.0378 | 1 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0098 | 0.1905 | 0.1905 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.1905 | 0.1905 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.058 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0378 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0052 | 0.058 | 0.058 |
Loa Loa (eye worm) | TAR-binding protein | 0.0378 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0308 | 0.7992 | 0.7992 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0051 | 0.0051 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0098 | 0.1905 | 0.1905 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.058 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.058 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.058 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0308 | 0.7992 | 0.7992 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0098 | 0.1905 | 0.1905 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.058 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0378 | 1 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0098 | 0.1905 | 0.1905 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0098 | 0.1905 | 0.1905 |
Schistosoma mansoni | hypothetical protein | 0.0098 | 0.1905 | 0.1905 |
Schistosoma mansoni | tar DNA-binding protein | 0.0378 | 1 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0378 | 1 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0134 | 0.2948 | 0.2948 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.058 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0098 | 0.1905 | 0.1905 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0308 | 0.7992 | 0.7992 |
Schistosoma mansoni | hypothetical protein | 0.0211 | 0.5175 | 0.5175 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0378 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1905 | 0.1905 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.