Detailed information for compound 910248

Basic information

Technical information
  • TDR Targets ID: 910248
  • Name: 8-[(bis(2-methylpropyl)amino)methyl]-7-hydrox y-4-phenylchromen-2-one
  • MW: 379.492 | Formula: C24H29NO3
  • H donors: 1 H acceptors: 2 LogP: 5.23 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(CN(Cc1c(O)ccc2c1oc(=O)cc2c1ccccc1)CC(C)C)C
  • InChi: 1S/C24H29NO3/c1-16(2)13-25(14-17(3)4)15-21-22(26)11-10-19-20(12-23(27)28-24(19)21)18-8-6-5-7-9-18/h5-12,16-17,26H,13-15H2,1-4H3
  • InChiKey: NBWDJIAAGSPKRS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 8-[(diisobutylamino)methyl]-7-hydroxy-4-phenyl-chromen-2-one
  • 8-[(diisobutylamino)methyl]-7-hydroxy-4-phenyl-2-chromenone
  • 8-[(diisobutylamino)methyl]-7-hydroxy-4-phenyl-coumarin
  • 8-[(bis(2-methylpropyl)amino)methyl]-7-hydroxy-4-phenyl-chromen-2-one
  • ST5181385
  • Oprea1_524030
  • EU-0040329

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0019 0.0196 0.028
Brugia malayi steroid hormone receptor 0.0011 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Onchocerca volvulus 0.0036 0.0599 0.235
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0025 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0025 0.0036
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0025 0.0025
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0025 0.0025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0019 0.0196 0.3267
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.199 0.199
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Loa Loa (eye worm) hypothetical protein 0.021 0.4712 0.6725
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0025 0.0025
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0097 0.205 0.205
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0097 0.205 0.205
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0599 0.0599
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0388 0.648
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0025 0.0036
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0599 0.0856
Echinococcus multilocularis dnaJ subfamily B 0.0433 1 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0196 0.0048
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0599 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0097 0.205 0.205
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0025 0.0036
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0345 0.0348
Loa Loa (eye worm) latrophilin receptor protein 2 0.0097 0.205 0.2925
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0025 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0025 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Loa Loa (eye worm) hypothetical protein 0.0019 0.0196 0.028
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0025 0.0025
Echinococcus granulosus mixed lineage leukemia protein mll 0.0029 0.045 0.045
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.081
Giardia lamblia Replication factor C, subunit 1 0.001 0 0.5
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.045 0.045
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0025 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Schistosoma mansoni hypothetical protein 0.0433 1 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Mycobacterium ulcerans hypothetical protein 0.0025 0.0345 0.5755
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0345 0.0492
Loa Loa (eye worm) hypothetical protein 0.0036 0.0599 0.0856
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0307 0.7007 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0345 0.0492
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0599 1
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0025 0.0025
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.199 0.199
Toxoplasma gondii ABC1 family protein 0.0036 0.0599 0.1187
Toxoplasma gondii histone lysine methyltransferase SET1 0.0224 0.5052 1
Schistosoma mansoni cpg binding protein 0.0125 0.271 0.271
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0025 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0025 0.0036
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0345 0.5755
Brugia malayi beta-lactamase family protein 0.0036 0.0599 0.0856
Loa Loa (eye worm) beta-lactamase 0.0036 0.0599 0.0856
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0012 0.0049 0.081
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0025 0.0025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0025 0.0025
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0345 0.5755
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0196 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0599 0.0856
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0388 0.648
Loa Loa (eye worm) CXXC zinc finger family protein 0.0118 0.2551 0.3641
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0307 0.7007 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0025 0.0025
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0025 0.0098
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Onchocerca volvulus 0.0036 0.0599 0.235
Mycobacterium tuberculosis Conserved protein 0.0036 0.0599 0.0859
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Echinococcus granulosus cpg binding protein 0.0125 0.271 0.271
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0388 0.648
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0037 0.062 0.062
Loa Loa (eye worm) hypothetical protein 0.0025 0.0345 0.0492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0025 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0025 0.0036
Schistosoma mansoni myst-related protein 0.0014 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Brugia malayi F/Y-rich N-terminus family protein 0.0036 0.0609 0.0869
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0345 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0599 0.0856
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0095 0.199 0.199
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0025 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0095 0.1583
Loa Loa (eye worm) hypothetical protein 0.0097 0.205 0.2925
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.045 0.045
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0025 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0025 0.0025
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0345 0.0348
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0156 0.0156
Onchocerca volvulus 0.0118 0.2551 1
Trypanosoma brucei ISWI complex protein 0.0012 0.0049 0.081
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0025 0.0025
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0599 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0599 0.0856
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0025 0.0036
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.001 0 0.5
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0388 0.648
Mycobacterium leprae Probable lipase LipE 0.0036 0.0599 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0599 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0388 0.648
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0599 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0599 0.0859
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0097 0.205 0.205
Trypanosoma cruzi ISWI complex protein 0.0012 0.0049 0.081
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0025 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0345 0.5755
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0599 0.0599
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0599 1
Brugia malayi nuclear hormone receptor 0.0011 0.0025 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0025 0.0036
Brugia malayi latrophilin 2 splice variant baaae 0.021 0.4712 0.6725
Schistosoma mansoni cpg binding protein 0.0118 0.2551 0.2551
Schistosoma mansoni coup transcription factor 0.0011 0.0025 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0599 1
Brugia malayi nuclear receptor NHR-88 0.0011 0.0025 0.0036
Treponema pallidum DNA ligase (lig) 0.001 0 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Brugia malayi CXXC zinc finger family protein 0.0118 0.2551 0.3641
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0599 0.0859
Brugia malayi ecdysteroid receptor 0.0011 0.0025 0.0036
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0599 0.0599
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0599 0.0859
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0025 0.0098
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0345 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0025 0.0025
Plasmodium falciparum acyl-CoA synthetase 0.0019 0.0196 1
Echinococcus multilocularis GPCR, family 2 0.0097 0.205 0.205
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0025 0.0025
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0388 0.648
Schistosoma mansoni cpg binding protein 0.0125 0.271 0.271
Schistosoma mansoni hypothetical protein 0.0097 0.205 0.205
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0599 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0025 0.0036
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0025 0.0098
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0345 0.5755
Brugia malayi Latrophilin receptor protein 2 0.0097 0.205 0.2925
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0345 0.5755
Leishmania major hypothetical protein, conserved 0.0036 0.0599 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0251 0.5685 0.5685
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.199 0.199
Mycobacterium ulcerans hypothetical protein 0.0036 0.0599 1
Schistosoma mansoni hypothetical protein 0.0097 0.205 0.205
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0599 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0307 0.7007 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0025 0.0036
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0025 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0196 0.028
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0599 0.0856
Trichomonas vaginalis hypothetical protein 0.0014 0.0095 0.1583
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0095 0.199 0.2839
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0345 0.5755
Onchocerca volvulus 0.0036 0.0599 0.235
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0388 0.648
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0345 0.5755
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0037 0.062 0.062
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.199 0.199
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0025 0.0345 0.0492
Loa Loa (eye worm) hypothetical protein 0.0011 0.0025 0.0036
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0025 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0025 0.0036
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0025 0.0025
Brugia malayi beta-lactamase 0.0036 0.0599 0.0856
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0345 0.0492
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0599 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0345 0.5755
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0599 0.0859
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0095 0.199 0.199
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0025 0.0036
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0599 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0599 0.0859
Entamoeba histolytica hypothetical protein 0.0014 0.0085 0.2459
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0345 0.5755
Echinococcus granulosus GPCR family 2 0.0097 0.205 0.205
Trichomonas vaginalis helicase, putative 0.0027 0.0388 0.648
Brugia malayi beta-lactamase family protein 0.0036 0.0599 0.0856
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0097 0.205 0.205
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0388 0.648
Loa Loa (eye worm) hypothetical protein 0.0036 0.0599 0.0856
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0029 0.045 0.045
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0025 0.0025
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0599 0.0599
Plasmodium vivax acyl-CoA synthetase, putative 0.0019 0.0196 0.3267
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0599 0.0859
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0388 0.648
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0025 0.0025
Onchocerca volvulus 0.0025 0.0345 0.1353
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0025 0.0036
Echinococcus multilocularis cpg binding protein 0.0125 0.271 0.271
Plasmodium falciparum zinc finger protein, putative 0.0014 0.0085 0.4332
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0599 0.0859
Loa Loa (eye worm) hypothetical protein 0.0036 0.0599 0.0856
Brugia malayi Calcitonin receptor-like protein seb-1 0.0307 0.7007 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0025 0.0036
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0095 0.1583
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0025 0.0025
Schistosoma mansoni myst-related protein 0.0014 0.0085 0.0085
Onchocerca volvulus 0.0011 0.0025 0.0098
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.515 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0025 0.0025
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0025 0.0025
Trichomonas vaginalis esterase, putative 0.0036 0.0599 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0095 0.199 0.2839
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0345 0.0492
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0097 0.205 0.2925
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0097 0.205 0.205
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0025 0.0025
Mycobacterium ulcerans beta-lactamase 0.0036 0.0599 1
Schistosoma mansoni hypothetical protein 0.021 0.4712 0.4712
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0019 0.0196 0.028
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0095 0.199 0.199
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0025 0.0036
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.045 0.045
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0345 1
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0599 0.0859
Mycobacterium ulcerans lipase LipD 0.0036 0.0599 1
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0025 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0196 0.028
Mycobacterium tuberculosis Conserved protein 0.0036 0.0599 0.0859
Loa Loa (eye worm) histone methyltransferase 0.0037 0.062 0.0885
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0599 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0049 0.081
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0025 0.0025

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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