Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | tar DNA-binding protein | 0.0273 | 0.3721 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0321 | 0.4509 | 0.4509 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0102 | 0.0927 | 0.2491 |
Schistosoma mansoni | tar DNA-binding protein | 0.0273 | 0.3721 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0927 | 0.2491 |
Echinococcus multilocularis | tar DNA binding protein | 0.0273 | 0.3721 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0102 | 0.0927 | 0.2491 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0273 | 0.3721 | 0.3721 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0102 | 0.0927 | 0.0927 |
Loa Loa (eye worm) | RNA binding protein | 0.0273 | 0.3721 | 0.3721 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0102 | 0.0927 | 0.2491 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0321 | 0.4509 | 0.4509 |
Echinococcus granulosus | tar DNA binding protein | 0.0273 | 0.3721 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0273 | 0.3721 | 0.3721 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.4509 | 0.4509 |
Schistosoma mansoni | tar DNA-binding protein | 0.0273 | 0.3721 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0658 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0321 | 0.4509 | 0.4509 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0927 | 0.2491 |
Schistosoma mansoni | hypothetical protein | 0.022 | 0.2851 | 0.7661 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1826 | 0.1826 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0927 | 0.0927 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0102 | 0.0927 | 0.0927 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0927 | 0.2491 |
Brugia malayi | hypothetical protein | 0.0157 | 0.1826 | 0.1826 |
Schistosoma mansoni | tar DNA-binding protein | 0.0273 | 0.3721 | 1 |
Brugia malayi | RNA binding protein | 0.0273 | 0.3721 | 0.3721 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0658 | 1 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0102 | 0.0927 | 0.2491 |
Loa Loa (eye worm) | hypothetical protein | 0.022 | 0.2851 | 0.2851 |
Schistosoma mansoni | hypothetical protein | 0.0102 | 0.0927 | 0.2491 |
Echinococcus multilocularis | GPCR, family 2 | 0.0102 | 0.0927 | 0.2491 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0102 | 0.0927 | 0.2491 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.022 | 0.2851 | 0.2851 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0102 | 0.0927 | 0.0927 |
Brugia malayi | TAR-binding protein | 0.0273 | 0.3721 | 0.3721 |
Schistosoma mansoni | tar DNA-binding protein | 0.0273 | 0.3721 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0273 | 0.3721 | 0.3721 |
Onchocerca volvulus | 0.0157 | 0.1826 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.