TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 476.36 | Formula: C23H26BrNO5
H donors: 2 H acceptors: 3 LogP: 3.96 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: C=CCOC(=O)C1=C(C)N=C2C(=C(O)CC(C2)(C)C)C1c1cc(Br)c(c(c1)OC)O
InChi: 1S/C23H26BrNO5/c1-6-7-30-22(28)18-12(2)25-15-10-23(3,4)11-16(26)20(15)19(18)13-8-14(24)21(27)17(9-13)29-5/h6,8-9,19,26-27H,1,7,10-11H2,2-5H3
InChiKey: BIXFJBNZMPAOPC-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	TAR-binding protein	0.0399	0.4648	0.4648
Schistosoma mansoni	Smad4	0.0023	0.0165	0.021
Mycobacterium tuberculosis	Probable polyketide synthase Pks9	0.0014	0.0056	0.097
Brugia malayi	Smad1	0.0052	0.0508	0.0508
Echinococcus granulosus	smad	0.0052	0.0508	0.0646
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD	0.0025	0.0182	0.1334
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.0079	0.0828	0.1053
Trypanosoma cruzi	PAB1-binding protein , putative	0.0081	0.0854	1
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsD	0.0025	0.0182	0.1334
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0016	0.0078	0.01
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0018	0.0109	0.0109
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0399	0.4648	0.4648
Onchocerca volvulus		0.0043	0.04	0.1858
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0018	0.0109	0.0139
Mycobacterium ulcerans	Type I modular polyketide synthase	0.0025	0.0182	0.1334
Loa Loa (eye worm)	hypothetical protein	0.0847	1	1
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0079	0.0828	1
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0016	0.0078	0.01
Loa Loa (eye worm)	fatty acid synthase	0.0024	0.0178	0.0178
Toxoplasma gondii	isocitrate dehydrogenase	0.0016	0.0078	0.0919
Loa Loa (eye worm)	MH1 domain-containing protein	0.0052	0.0508	0.0508
Brugia malayi	hypothetical protein	0.0081	0.0854	0.0854
Schistosoma mansoni	Smad4	0.0023	0.0165	0.021
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0079	0.0828	0.967
Schistosoma mansoni	microtubule-associated protein tau	0.0668	0.7863	1
Echinococcus multilocularis	tar DNA binding protein	0.0399	0.4648	0.5912
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0079	0.0828	0.97
Schistosoma mansoni	hypothetical protein	0.0268	0.3088	0.3927
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0053	0.0053
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.0052	0.0508	0.0646
Toxoplasma gondii	type I fatty acid synthase, putative	0.0018	0.0098	0.1144
Echinococcus multilocularis	microtubule associated protein 2	0.0668	0.7863	1
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.0052	0.0504	1
Brugia malayi	MH2 domain containing protein	0.0052	0.0508	0.0508
Loa Loa (eye worm)	hypothetical protein	0.0029	0.0231	0.0231
Schistosoma mansoni	tar DNA-binding protein	0.0399	0.4648	0.5912
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.0036	0.0322	0.0409
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsC	0.0026	0.0201	0.1579
Schistosoma mansoni	tar DNA-binding protein	0.0399	0.4648	0.5912
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0016	0.0078	0.01
Brugia malayi	MH2 domain containing protein	0.0023	0.0165	0.0165
Loa Loa (eye worm)	hypothetical protein	0.0081	0.0854	0.0854
Echinococcus multilocularis	mothers against decapentaplegic 6	0.0023	0.0165	0.021
Plasmodium falciparum	ataxin-2 like protein, putative	0.0081	0.0854	1
Brugia malayi	MH1 domain containing protein	0.0029	0.0231	0.0231
Toxoplasma gondii	AMP-binding enzyme domain-containing protein	0.0012	0.0037	0.0434
Echinococcus multilocularis	isocitrate dehydrogenase	0.0016	0.0078	0.01
Brugia malayi	AMP-binding enzyme family protein	0.0023	0.0163	0.0163
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0268	0.3088	0.3088
Brugia malayi	RNA recognition motif domain containing protein	0.0399	0.4648	0.4648
Toxoplasma gondii	exonuclease III APE	0.0018	0.0109	0.1281
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0018	0.0109	0.2051
Mycobacterium tuberculosis	Phenolpthiocerol synthesis type-I polyketide synthase PpsA	0.0025	0.0182	0.3519
Echinococcus granulosus	microtubule associated protein 2	0.0668	0.7863	1
Echinococcus multilocularis	smad	0.0052	0.0508	0.0646
Loa Loa (eye worm)	hypothetical protein	0.0268	0.3088	0.3088
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0027	0.0212	0.1727
Loa Loa (eye worm)	MH2 domain-containing protein	0.0023	0.0165	0.0165
Onchocerca volvulus	Mothers against decapentaplegic homolog	0.0023	0.0165	0.0769
Brugia malayi	isocitrate dehydrogenase	0.0016	0.0078	0.0078
Trypanosoma brucei	PAB1-binding protein , putative	0.0081	0.0854	1
Toxoplasma gondii	LsmAD domain-containing protein	0.0081	0.0854	1
Loa Loa (eye worm)	transcription factor SMAD2	0.0761	0.8976	0.8976
Loa Loa (eye worm)	hypothetical protein	0.0579	0.6801	0.6801
Brugia malayi	MH1 domain containing protein	0.0052	0.0508	0.0508
Echinococcus granulosus	TGF beta signal transducer SmadC	0.0052	0.0508	0.0646
Brugia malayi	MH2 domain containing protein	0.0052	0.0508	0.0508
Onchocerca volvulus	Fatty acid synthase homolog	0.0044	0.0418	0.1943
Plasmodium vivax	ataxin-2 like protein, putative	0.0081	0.0854	1
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0079	0.0828	1
Echinococcus granulosus	mothers against decapentaplegic 5	0.0052	0.0508	0.0646
Loa Loa (eye worm)	hypothetical protein	0.0079	0.0828	0.0828
Plasmodium falciparum	ataxin-2 like protein, putative	0.0081	0.0854	1
Brugia malayi	mothers against decapentaplegic homolog 3	0.0023	0.0165	0.0165
Brugia malayi	MH1 domain containing protein	0.0052	0.0508	0.0508
Mycobacterium leprae	Polyketide synthase Pks13	0.0037	0.0328	0.3283
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0079	0.0828	1
Mycobacterium tuberculosis	Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)	0.0016	0.0078	0.143
Mycobacterium leprae	PROBABLE THIOESTERASE TESA	0.002	0.0133	0.0678
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.0079	0.0828	1
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0189	0.2151	1
Mycobacterium ulcerans	polyketide synthase	0.0025	0.0182	0.1334
Mycobacterium ulcerans	multifunctional mycocerosic acid synthase membrane-associated Mas	0.0026	0.0201	0.1579
Echinococcus multilocularis	peptidase Clp (S14 family)	0.0052	0.0504	0.0642
Echinococcus multilocularis	Smad4	0.0052	0.0508	0.0646
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0268	0.3088	0.3927
Brugia malayi	hypothetical protein	0.0035	0.0311	0.0311
Loa Loa (eye worm)	MH1 domain-containing protein	0.0023	0.0165	0.0165
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.0079	0.0828	0.1053
Mycobacterium ulcerans	thioesterase TesA	0.002	0.0133	0.0678
Loa Loa (eye worm)	Smad1	0.0052	0.0508	0.0508
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0109	0.0398
Toxoplasma gondii	hypothetical protein	0.0027	0.0212	0.2487
Mycobacterium tuberculosis	Polyketide synthase Pks13	0.0037	0.0328	0.644
Loa Loa (eye worm)	acyl carrier protein	0.0011	0.0024	0.0024
Mycobacterium ulcerans	Type I modular polyketide synthase	0.0025	0.0182	0.1334
Mycobacterium tuberculosis	Phenolpthiocerol synthesis type-I polyketide synthase PpsD	0.0025	0.0182	0.3519
Mycobacterium ulcerans	polyketide synthase Pks13	0.0037	0.0328	0.3283
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)	0.0052	0.0504	0.5657
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0109	0.0398
Echinococcus granulosus	mothers against decapentaplegic 6	0.0023	0.0165	0.021
Mycobacterium tuberculosis	Polyketide synthase Pks2	0.0024	0.0173	0.3337
Mycobacterium tuberculosis	Probable polyketide synthase Pks1	0.0018	0.01	0.1855
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0268	0.3088	0.3927
Schistosoma mansoni	Smad4	0.0052	0.0508	0.0646
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0035	0.0311	0.0395
Brugia malayi	oxidoreductase, zinc-binding dehydrogenase family protein	0.0047	0.0445	0.0445
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsA	0.002	0.0125	0.0565
Loa Loa (eye worm)	TAR-binding protein	0.0399	0.4648	0.4648
Mycobacterium tuberculosis	Phenyloxazoline synthase MbtB (phenyloxazoline synthetase)	0.0023	0.0163	0.313
Plasmodium falciparum	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0018	0.0109	0.0398
Brugia malayi	exodeoxyribonuclease III family protein	0.0018	0.0109	0.0109
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA	0.0025	0.0182	0.1334
Loa Loa (eye worm)	MH2 domain-containing protein	0.0761	0.8976	0.8976
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.0052	0.0504	1
Loa Loa (eye worm)	MH2 domain-containing protein	0.0052	0.0508	0.0508
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0079	0.0828	0.5
Toxoplasma gondii	isocitrate dehydrogenase	0.0016	0.0078	0.0919
Trypanosoma cruzi	PAB1-binding protein , putative	0.0081	0.0854	1
Schistosoma mansoni	tar DNA-binding protein	0.0399	0.4648	0.5912
Echinococcus granulosus	mothers against decapentaplegic 2	0.0023	0.0165	0.021
Echinococcus granulosus	tar DNA binding protein	0.0399	0.4648	0.5912
Brugia malayi	Isocitrate dehydrogenase	0.0016	0.0078	0.0078
Schistosoma mansoni	smad1 5 8 and	0.0052	0.0508	0.0646
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0018	0.0109	0.0356
Loa Loa (eye worm)	hypothetical protein	0.0023	0.0165	0.0165
Schistosoma mansoni	hypothetical protein	0.0036	0.0322	0.0409
Brugia malayi	latrophilin 2 splice variant baaae	0.0579	0.6801	0.6801
Schistosoma mansoni	hypothetical protein	0.0268	0.3088	0.3927
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0079	0.0828	0.5
Echinococcus granulosus	peptidase Clp S14 family	0.0052	0.0504	0.0642
Mycobacterium tuberculosis	Probable membrane bound polyketide synthase Pks6	0.0037	0.0328	0.644
Mycobacterium tuberculosis	Probable thioesterase TesA	0.002	0.0133	0.2534
Echinococcus multilocularis	mothers against decapentaplegic 2	0.0023	0.0165	0.021
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0079	0.0828	0.97
Schistosoma mansoni	ap endonuclease	0.0018	0.0109	0.0139
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0847	1	1
Mycobacterium tuberculosis	Probable multifunctional mycocerosic acid synthase membrane-associated Mas	0.0026	0.0201	0.3885
Mycobacterium ulcerans	phenolpthiocerol synthesis type-I polyketide synthase PpsB	0.002	0.0125	0.0565
Echinococcus granulosus	Smad4	0.0052	0.0508	0.0646
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0018	0.0109	0.0398
Loa Loa (eye worm)	hypothetical protein	0.0189	0.2151	0.2151
Giardia lamblia	Endonuclease/Exonuclease/phosphatase	0.0018	0.0109	0.5
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.0023	0.0163	0.0163
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0109	0.5
Mycobacterium tuberculosis	Probable polyketide synthase Pks8	0.002	0.0129	0.2442
Brugia malayi	RNA binding protein	0.0399	0.4648	0.4648
Mycobacterium leprae	Probable polyketide synthase Pks1	0.0026	0.0201	0.1579
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.0079	0.0828	1
Echinococcus multilocularis	mothers against decapentaplegic 5	0.0052	0.0508	0.0646
Schistosoma mansoni	smad1 5 8 and	0.0052	0.0508	0.0646
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0079	0.0828	0.967
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0268	0.3088	0.3927
Mycobacterium leprae	ATP-dependent Clp protease proteolytic subunit 1	0.0027	0.0212	0.1738
Mycobacterium leprae	Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas	0.0026	0.0201	0.1579
Mycobacterium tuberculosis	Phenolpthiocerol synthesis type-I polyketide synthase PpsC	0.0025	0.0182	0.3519
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC	0.0026	0.0201	0.1579
Schistosoma mansoni	hypothetical protein	0.0579	0.6801	0.8649
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0268	0.3088	0.3927
Schistosoma mansoni	smad	0.0023	0.0165	0.021
Brugia malayi	N-terminal motif family protein	0.0189	0.2151	0.2151
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0027	0.0212	0.1433
Toxoplasma gondii	beta-ketoacyl synthase, N-terminal domain-containing protein	0.0016	0.0079	0.0927
Echinococcus multilocularis	GPCR, family 2	0.0268	0.3088	0.3927
Brugia malayi	MH2 domain containing protein	0.0761	0.8976	0.8976
Schistosoma mansoni	tar DNA-binding protein	0.0399	0.4648	0.5912
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0016	0.0078	0.01
Entamoeba histolytica	hypothetical protein	0.0035	0.0311	1
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.0052	0.0508	0.0646
Mycobacterium ulcerans	polyketide synthase	0.0026	0.0201	0.1579
Brugia malayi	Beta-ketoacyl synthase, N-terminal domain containing protein	0.0025	0.0182	0.0182
Mycobacterium tuberculosis	Polyketide synthase Pks12	0.0026	0.0201	0.3885
Schistosoma mansoni	peptidase Clp (S14 family)	0.0079	0.0828	0.1053
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0016	0.0078	0.01
Schistosoma mansoni	smad	0.0052	0.0508	0.0646
Brugia malayi	Probable ClpP-like protease	0.0079	0.0828	0.0828
Entamoeba histolytica	hypothetical protein	0.0035	0.0311	1
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.0016	0.0078	0.01
Mycobacterium tuberculosis	Probable polyketide synthase Pks5	0.0024	0.0173	0.3337
Schistosoma mansoni	transcription factor LCR-F1	0.0035	0.0311	0.0395
Mycobacterium ulcerans	thioesterase	0.002	0.0133	0.0678
Schistosoma mansoni	hypothetical protein	0.0035	0.0311	0.0395
Mycobacterium leprae	PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB	0.002	0.0125	0.0565
Schistosoma mansoni	hypothetical protein	0.0268	0.3088	0.3927
Brugia malayi	hypothetical protein	0.0052	0.0512	0.0512
Schistosoma mansoni	smad1 5 8 and	0.0052	0.0508	0.0646
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0018	0.0109	0.0398
Loa Loa (eye worm)	hypothetical protein	0.0041	0.0382	0.0382
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0268	0.3088	0.3088
Trichomonas vaginalis	ap endonuclease, putative	0.0018	0.0109	0.5
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0035	0.0311	0.0395
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0847	1	1
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0027	0.0212	0.1727
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0016	0.0078	0.0078
Schistosoma mansoni	tar DNA-binding protein	0.0399	0.4648	0.5912
Echinococcus granulosus	GPCR family 2	0.0268	0.3088	0.3927
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0018	0.0109	0.0398
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.0036	0.0322	0.0409
Leishmania major	hypothetical protein, conserved	0.0081	0.0854	1
Brugia malayi	MH1 domain containing protein	0.0029	0.0231	0.0231
Mycobacterium tuberculosis	Probable polyketide synthase Pks7	0.0026	0.0201	0.3885
Mycobacterium ulcerans	Type I modular polyketide synthase	0.0025	0.0182	0.1334
Entamoeba histolytica	hypothetical protein	0.0035	0.0311	1
Entamoeba histolytica	hypothetical protein	0.0035	0.0311	1
Loa Loa (eye worm)	nuclear factor I	0.0029	0.0231	0.0231
Schistosoma mansoni	ap endonuclease	0.0018	0.0109	0.0139
Brugia malayi	Latrophilin receptor protein 2	0.0268	0.3088	0.3088
Schistosoma mansoni	hypothetical protein	0.0268	0.3088	0.3927
Toxoplasma gondii	type I fatty acid synthase, putative	0.0026	0.0201	0.2349
Onchocerca volvulus		0.0023	0.0163	0.0758
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0018	0.0109	0.0139
Loa Loa (eye worm)	RNA binding protein	0.0399	0.4648	0.4648

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 911129