Detailed information for compound 911299

Basic information

Technical information
  • TDR Targets ID: 911299
  • Name: 1-(2-imino-3-methylbenzimidazol-1-yl)-3-(phen oxy)propan-2-ol
  • MW: 297.352 | Formula: C17H19N3O2
  • H donors: 1 H acceptors: 1 LogP: 2.07 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(Cn1c2ccccc2n(c1=N)C)COc1ccccc1
  • InChi: 1S/C17H19N3O2/c1-19-15-9-5-6-10-16(15)20(17(19)18)11-13(21)12-22-14-7-3-2-4-8-14/h2-10,13,18,21H,11-12H2,1H3
  • InChiKey: VEDNAASDVOTMIR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(2-imino-3-methyl-benzimidazol-1-yl)-3-(phenoxy)propan-2-ol
  • 1-(2-imino-3-methyl-1-benzimidazolyl)-3-(phenoxy)propan-2-ol
  • 1-(2-Imino-3-methyl-2,3-dihydro-benzoimidazol-1-yl)-3-phenoxy-propan-2-ol
  • BAS 01044564
  • Oprea1_280378
  • STK029681
  • Oprea1_773211

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0022 0.0025
Brugia malayi beta-lactamase family protein 0.0081 0.1187 0.1367
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0977 0.1126
Mycobacterium leprae conserved hypothetical protein 0.0081 0.1187 0.2818
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0058 0.0738 0.085
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0081 0.1187 0.0498
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.1187 0.1007
Onchocerca volvulus 0.0081 0.1187 1
Echinococcus granulosus histone acetyltransferase MYST2 0.006 0.0779 0.093
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0134 0.2275 1
Onchocerca volvulus 0.0036 0.0278 0.2195
Echinococcus granulosus histone acetyltransferase KAT2B 0.0134 0.2275 0.2716
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0022 0.0025
Brugia malayi hypothetical protein 0.0158 0.2763 0.3182
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.1637 0.1886
Mycobacterium ulcerans lipase LipD 0.0081 0.1187 0.3829
Mycobacterium tuberculosis Probable lipase LipD 0.0081 0.1187 0.0498
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0022 0.0026
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0022 0.0025
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0378 0.7215 0.831
Entamoeba histolytica hypothetical protein 0.0158 0.2763 0.5206
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.063 0.0725
Brugia malayi mbt repeat family protein 0.0053 0.063 0.0725
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.1187 0.1007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0378 0.7215 0.831
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0022 0.0025
Schistosoma mansoni hypothetical protein 0.0033 0.0212 0.0244
Leishmania major methionyl-tRNA synthetase, putative 0.0058 0.0726 0.1154
Echinococcus multilocularis GPCR, family 2 0.0033 0.0212 0.0244
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Brugia malayi nuclear receptor NHR-88 0.0023 0.0022 0.0025
Brugia malayi steroid hormone receptor 0.0023 0.0022 0.0025
Onchocerca volvulus 0.0053 0.063 0.5217
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0022 0.0025
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0022 0.0025
Leishmania major hypothetical protein, conserved 0.0081 0.1187 0.1888
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0077 0.1123 0.1342
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0378 0.7215 0.831
Schistosoma mansoni hypothetical protein 0.0023 0.0018 0.0021
Giardia lamblia Methionyl-tRNA synthetase 0.0058 0.0726 0.1368
Onchocerca volvulus 0.0081 0.1187 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0158 0.2763 0.3182
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.045 0.8682 1
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0134 0.2275 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0022 0.0026
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0081 0.1187 0.1367
Schistosoma mansoni hypothetical protein 0.0033 0.0212 0.0244
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0023 0.0022 0.0026
Echinococcus multilocularis methionine tRNA synthetase 0.0058 0.0726 0.0836
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0157 0.2741 0.3871
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.1637 0.1886
Leishmania major mitochondrial DNA polymerase beta 0.0332 0.6289 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0022 0.0025
Onchocerca volvulus 0.0081 0.1187 1
Brugia malayi mbt repeat family protein 0.0053 0.063 0.0725
Echinococcus multilocularis zinc finger protein 0.0033 0.0217 0.025
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0158 0.2763 0.3299
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0022 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.1187 0.1188
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.2741 0.4357
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0022 0.0025
Mycobacterium tuberculosis Conserved protein 0.0081 0.1187 0.0498
Loa Loa (eye worm) hypothetical protein 0.007 0.0977 0.1126
Mycobacterium tuberculosis Conserved hypothetical protein 0.0175 0.3101 0.2561
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Mycobacterium tuberculosis Probable esterase LipL 0.0081 0.1187 0.0498
Trichomonas vaginalis penicillin-binding protein, putative 0.0081 0.1187 0.1007
Loa Loa (eye worm) hypothetical protein 0.0081 0.1187 0.1367
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0022 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0022 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0081 0.1187 0.1367
Wolbachia endosymbiont of Brugia malayi methionyl-tRNA synthetase 0.0058 0.0726 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0022 0.0026
Schistosoma mansoni methionine-tRNA synthetase 0.0058 0.0726 0.0836
Brugia malayi methionyl-tRNA synthetase 0.0058 0.0726 0.0836
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Plasmodium falciparum histone acetyltransferase GCN5 0.0121 0.1999 1
Schistosoma mansoni retinoic acid receptor RXR 0.0023 0.0022 0.0025
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0022 0.0026
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0332 0.6289 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0435 0.8374 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0378 0.7215 0.831
Schistosoma mansoni sex comb on midleg homolog 0.0053 0.063 0.0725
Entamoeba histolytica hypothetical protein 0.0158 0.2763 0.5206
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0022 0.0025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0022 0.0026
Brugia malayi ecdysteroid receptor 0.0023 0.0022 0.0025
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.2016 0.2322
Echinococcus multilocularis histone acetyltransferase MYST2 0.006 0.0779 0.0897
Plasmodium falciparum methionine--tRNA ligase 0.0058 0.0726 0.3631
Entamoeba histolytica hypothetical protein 0.0158 0.2763 0.5206
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.6289 1
Loa Loa (eye worm) hypothetical protein 0.0043 0.0419 0.0483
Trypanosoma brucei hypothetical protein, conserved 0.0081 0.1187 0.1188
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0134 0.2275 1
Brugia malayi Bromodomain containing protein 0.0094 0.1469 0.1692
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0053 0.063 0.5217
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0022 0.0025
Giardia lamblia Fructose-bisphosphate aldolase 0.0284 0.5307 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0022 0.0025
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0081 0.1187 0.1367
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Toxoplasma gondii hypothetical protein 0.0054 0.0639 0.2807
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0022 0.0026
Trichomonas vaginalis bromodomain-containing protein, putative 0.0134 0.2275 0.3381
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0081 0.1187 0.1367
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0022 0.0025
Chlamydia trachomatis methionine--tRNA ligase 0.0022 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0524 0.0604
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0212 0.0244
Loa Loa (eye worm) bromodomain containing protein 0.0031 0.0174 0.02
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Echinococcus granulosus zinc finger protein 0.0033 0.0217 0.0259
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0081 0.1187 0.1367
Trypanosoma cruzi methionyl-tRNA synthetase, putative 0.0058 0.0726 0.0391
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0022 0.0025
Echinococcus multilocularis SAM and MBT domain containing protein 0.0053 0.063 0.0725
Brugia malayi PHD-finger family protein 0.0039 0.0337 0.0388
Entamoeba histolytica acetyltransferase, GNAT family 0.0121 0.1999 0.3766
Entamoeba histolytica hypothetical protein 0.0158 0.2763 0.5206
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Echinococcus granulosus methionine tRNA synthetase 0.0058 0.0726 0.0867
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0213 0.3884 0.4474
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0022 0.0025
Trichomonas vaginalis penicillin-binding protein, putative 0.0081 0.1187 0.1007
Loa Loa (eye worm) hypothetical protein 0.0081 0.1187 0.1367
Mycobacterium tuberculosis Conserved protein 0.0081 0.1187 0.0498
Brugia malayi Bromodomain containing protein 0.0054 0.064 0.0737
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0022 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0022 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0022 0.0025
Mycobacterium ulcerans beta-lactamase 0.0081 0.1187 0.3829
Schistosoma mansoni transcription factor LCR-F1 0.0158 0.2763 0.3182
Loa Loa (eye worm) hypothetical protein 0.0103 0.1637 0.1886
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0081 0.1187 0.1367
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0022 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0022 0.0025
Loa Loa (eye worm) beta-lactamase 0.0081 0.1187 0.1367
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0022 0.0025
Loa Loa (eye worm) acetyltransferase 0.045 0.8682 1
Schistosoma mansoni hypothetical protein 0.007 0.0977 0.1126
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.5307 1
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0139 0.2363 0.7622
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0022 0.0025
Loa Loa (eye worm) hypothetical protein 0.0048 0.0524 0.0604
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0022 0.0025
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0139 0.2363 0.1766
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0022 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0022 0.0025
Schistosoma mansoni hypothetical protein 0.0158 0.2763 0.3182
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0081 0.1187 0.0498
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0018 0.0021
Mycobacterium ulcerans hypothetical protein 0.0081 0.1187 0.3829
Loa Loa (eye worm) hypothetical protein 0.0053 0.063 0.0725
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0022 0.0025
Giardia lamblia Histone acetyltransferase GCN5 0.0121 0.1999 0.3766
Echinococcus granulosus beta LACTamase domain containing family member 0.0081 0.1187 0.1418
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0378 0.7215 0.8616
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0212 0.0244
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0134 0.2275 0.3381
Schistosoma mansoni hypothetical protein 0.0327 0.6189 0.7129
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0378 0.7215 0.831
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0022 0.0025
Echinococcus multilocularis polycomb protein SCMH1 0.0053 0.063 0.0725
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0157 0.2741 0.3871
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0707 0.0358
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Trypanosoma brucei methionyl-tRNA synthetase, putative 0.0058 0.0726 0.0391
Loa Loa (eye worm) methionyl-tRNA synthetase 0.0058 0.0726 0.0836
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0332 0.6289 1
Schistosoma mansoni zinc finger protein 0.0033 0.0217 0.025
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0081 0.1187 0.3829
Onchocerca volvulus 0.0048 0.0524 0.4313
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0022 0.0025
Trichomonas vaginalis D-aminoacylase, putative 0.0081 0.1187 0.1007
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0284 0.5307 1
Loa Loa (eye worm) hypothetical protein 0.006 0.0779 0.0897
Loa Loa (eye worm) hypothetical protein 0.0079 0.115 0.1325
Mycobacterium leprae Probable lipase LipE 0.0081 0.1187 0.2818
Echinococcus multilocularis tumor protein p63 0.0327 0.6197 0.7137
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0061 0.0071
Loa Loa (eye worm) hypothetical protein 0.0023 0.0022 0.0025
Schistosoma mansoni coup transcription factor 0.0023 0.0022 0.0025
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.006 0.0779 0.093
Brugia malayi beta-lactamase family protein 0.0081 0.1187 0.1367
Schistosoma mansoni hypothetical protein 0.0033 0.0212 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0022 0.0025
Plasmodium vivax methionine--tRNA ligase, putative 0.0058 0.0726 0.3191
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0022 0.0025
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0022 0.0025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.045 0.8682 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0022 0.0026
Mycobacterium tuberculosis Probable lipase LipE 0.0081 0.1187 0.0498
Brugia malayi nuclear hormone receptor 0.0023 0.0022 0.0025
Echinococcus granulosus tumor protein p63 0.0327 0.6197 0.74
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0022 0.0026
Chlamydia trachomatis leucine--tRNA ligase 0.0022 0 0.5
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0022 0.0025
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Echinococcus granulosus GPCR family 2 0.0033 0.0212 0.0253
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0212 0.0244
Trypanosoma cruzi hypothetical protein, conserved 0.0081 0.1187 0.1188
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0213 0.3884 0.4639
Schistosoma mansoni hypothetical protein 0.0033 0.0212 0.0244
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0022 0.0025
Plasmodium vivax hypothetical protein, conserved 0.0081 0.1187 0.5219
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.004 0.0364 0.0419
Toxoplasma gondii methionyl-tRNA synthetase 0.0058 0.0726 0.3191
Mycobacterium tuberculosis Probable hydrolase 0.0081 0.1187 0.0498
Brugia malayi MH2 domain containing protein 0.0121 0.2016 0.2322
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0022 0.0025
Toxoplasma gondii ABC1 family protein 0.0081 0.1187 0.5219
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0022 0.0025
Mycobacterium ulcerans hypothetical protein 0.0175 0.3101 1
Loa Loa (eye worm) MBCTL1 0.006 0.0779 0.0897
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Schistosoma mansoni bromodomain containing protein 0.0081 0.1204 0.1387
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.2016 0.2322
Loa Loa (eye worm) hypothetical protein 0.0081 0.1187 0.1367
Mycobacterium tuberculosis Conserved protein 0.0081 0.1187 0.0498
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.006 0.0779 0.0897
Schistosoma mansoni myelin transcription factor 1 myt1 0.006 0.0779 0.0897
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0077 0.1123 0.1294
Treponema pallidum fructose-bisphosphate aldolase 0.0284 0.5307 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0212 0.0244
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0212 0.0244
Loa Loa (eye worm) mbt repeat family protein 0.0053 0.063 0.0725
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0212 0.0253
Loa Loa (eye worm) hypothetical protein 0.0081 0.1187 0.1367
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.006 0.0779 0.0897
Loa Loa (eye worm) tyrosyl-tRNA synthetase 0.0036 0.0278 0.032
Brugia malayi acetyltransferase, GNAT family protein 0.045 0.8682 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.1637 0.1886
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0212 0.0253
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.004 0.0364 0.0435
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0022 0.0025
Echinococcus granulosus polycomb protein SCMH1 0.0053 0.063 0.0752
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0284 0.5307 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0378 0.7215 0.831
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0053 0.063 0.0725
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0061 0.0073
Brugia malayi beta-lactamase 0.0081 0.1187 0.1367
Loa Loa (eye worm) hypothetical protein 0.0033 0.0212 0.0244
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0378 0.7215 0.8616
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0139 0.2363 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0022 0.0025
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0378 0.7215 0.831
Echinococcus multilocularis beta LACTamase domain containing family member 0.0081 0.1187 0.1367
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0022 0.0025
Mycobacterium ulcerans methionyl-tRNA synthetase 0.0058 0.0726 0.2341
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0061 0.0071
Mycobacterium ulcerans esterase/lipase LipP 0.0081 0.1187 0.3829
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0081 0.1187 0.0498
Trichomonas vaginalis esterase, putative 0.0081 0.1187 0.1007
Echinococcus granulosus SAM and MBT domain containing protein 0.0053 0.063 0.0752
Loa Loa (eye worm) hypothetical protein 0.0056 0.0695 0.08
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0022 0.0025

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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