TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 433.51 | Formula: C24H30F3N3O
H donors: 0 H acceptors: 0 LogP: 4.8 Rotable bonds: 6
Rule of 5 violations (Lipinski): 1
SMILES: COc1ccccc1N1CCN(CC1)C1CCCN(C1)Cc1ccc(cc1)C(F)(F)F
InChi: 1S/C24H30F3N3O/c1-31-23-7-3-2-6-22(23)30-15-13-29(14-16-30)21-5-4-12-28(18-21)17-19-8-10-20(11-9-19)24(25,26)27/h2-3,6-11,21H,4-5,12-18H2,1H3
InChiKey: XSFSFULODWJHPX-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0294	0.0598	0.0594
Plasmodium falciparum	subtilisin-like protease 2	0.0179	0.0286	1
Onchocerca volvulus		0.0075	0.0004	0.0057
Loa Loa (eye worm)	beta-tubulin	0.0092	0.0049	0.0045
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.2112	0.5538	1
Onchocerca volvulus		0.0075	0.0004	0.0057
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	WD repeat domain, putative	0.014	0.018	0.0325
Echinococcus multilocularis	tubulin subunit beta	0.0092	0.0049	0.0058
Loa Loa (eye worm)	tubulin beta-1 chain	0.0092	0.0049	0.0045
Onchocerca volvulus		0.0075	0.0004	0.0057
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Brugia malayi	celfurPC protein	0.2945	0.7799	0.7799
Echinococcus granulosus	beta tubulin	0.0092	0.0049	0.0045
Brugia malayi	Subtilase family protein	0.0179	0.0286	0.0282
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Onchocerca volvulus		0.0075	0.0004	0.0057
Echinococcus granulosus	beta tubulin	0.0092	0.0049	0.0045
Toxoplasma gondii	subtilisin SUB10	0.0179	0.0286	0.7496
Onchocerca volvulus		0.0075	0.0004	0.0057
Entamoeba histolytica	tubulin family protein	0.0092	0.0049	0.5
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Mycobacterium ulcerans	membrane-anchored serine protease (mycosin), MycP4	0.0179	0.0286	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Mycobacterium ulcerans	proline rich membrane-anchored mycosin MycP5	0.0179	0.0286	0.5
Echinococcus multilocularis	Furin 1	0.1063	0.2687	0.3442
Toxoplasma gondii	subtilisin SUB6	0.0179	0.0286	0.7496
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Loa Loa (eye worm)	hypothetical protein	0.3755	1	1
Echinococcus granulosus	epidermal growth factor receptor	0.0387	0.085	0.0847
Toxoplasma gondii	subtilisin SUB5	0.0179	0.0286	0.7496
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Loa Loa (eye worm)	hypothetical protein	0.0294	0.0598	0.0594
Echinococcus granulosus	proprotein convertase subtilisin:kexin type 5	0.2112	0.5538	0.5536
Echinococcus multilocularis	Peptidase S8 S53, subtilisin kexin sedolisin	0.0179	0.0286	0.0362
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Onchocerca volvulus		0.0259	0.0503	0.8449
Echinococcus multilocularis	membrane bound transcription factor site 1	0.0179	0.0286	0.0362
Echinococcus multilocularis	tubulin, beta 4A class IVa	0.0092	0.0049	0.0058
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0097	0.0063	0.0604
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0092	0.0049	0.0088
Brugia malayi	Kringle domain containing protein	0.0097	0.0063	0.0059
Schistosoma mansoni	tubulin subunit beta	0.0092	0.0049	0.0045
Toxoplasma gondii	subtilisin SUB7	0.0179	0.0286	0.7496
Mycobacterium leprae	PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3)	0.0179	0.0286	0.5
Mycobacterium tuberculosis	Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like)	0.0179	0.0286	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0179	0.0286	0.0516
Leishmania major	subtilisin-like serine peptidase	0.0179	0.0286	1
Schistosoma mansoni	tripeptidyl-peptidase II (S08 family)	0.0179	0.0286	0.0282
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0179	0.0286	1
Schistosoma mansoni	furin-1 (S08 family)	0.1821	0.4748	0.4746
Echinococcus multilocularis	epidermal growth factor receptor	0.0387	0.085	0.1086
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Onchocerca volvulus		0.0075	0.0004	0.0057
Onchocerca volvulus		0.0075	0.0004	0.0057
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1063	0.2687	0.4852
Echinococcus multilocularis	tubulin beta 1 chain	0.0092	0.0049	0.0058
Plasmodium vivax	subtilisin-like serine protease, putative	0.0179	0.0286	1
Toxoplasma gondii	subtilisin SUB4	0.0179	0.0286	0.7496
Trypanosoma cruzi	hypothetical protein, conserved	0.0097	0.0063	0.0604
Trichomonas vaginalis	tubulin alpha chain, putative	0.0092	0.0049	0.0088
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0294	0.0598	0.0762
Onchocerca volvulus		0.0293	0.0595	1
Echinococcus granulosus	tubulin beta 4A class IVa	0.0092	0.0049	0.0045
Brugia malayi	Tubulin beta-1 chain	0.0092	0.0049	0.0045
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.3755	1	1
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.2112	0.5538	1
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0293	0.0595	0.0592
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0179	0.0286	0.0282
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Loa Loa (eye worm)	TK/EGFR protein kinase	0.0387	0.085	0.0847
Echinococcus granulosus	Tubulin beta 2C chain	0.0092	0.0049	0.0045
Onchocerca volvulus		0.0075	0.0004	0.0057
Echinococcus multilocularis	Tubulin beta 2C chain	0.0092	0.0049	0.0058
Loa Loa (eye worm)	tubulin beta chain	0.0092	0.0049	0.0045
Brugia malayi	Membrane-bound transcription factor site-1 protease precursor	0.0179	0.0286	0.0282
Brugia malayi	neuroendocrine convertase 1 precursor	0.3171	0.8415	0.8414
Echinococcus multilocularis	wd40 repeat	0.008	0.0016	0.0016
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	conserved hypothetical protein	0.0179	0.0286	0.0516
Onchocerca volvulus		0.0075	0.0004	0.0057
Echinococcus granulosus	Tubulin beta 2C chain	0.0092	0.0049	0.0045
Plasmodium falciparum	cysteine repeat modular protein 1	0.0097	0.0063	0.0604
Toxoplasma gondii	kringle domain-containing protein	0.0097	0.0063	0.0453
Onchocerca volvulus		0.0075	0.0004	0.0057
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Trichomonas vaginalis	proprotein convertase subtilisin/kexin type, putative	0.0884	0.2201	0.3974
Echinococcus granulosus	tissue type plasminogen activator	0.0097	0.0063	0.0059
Loa Loa (eye worm)	peptidase family M1 containing protein	0.0094	0.0055	0.0051
Loa Loa (eye worm)	hypothetical protein	0.0104	0.0082	0.0079
Schistosoma mansoni	neuropeptide receptor	0.0225	0.0411	0.0407
Loa Loa (eye worm)	hypothetical protein	0.0097	0.0063	0.0059
Toxoplasma gondii	subtilisin SUB9	0.0179	0.0286	0.7496
Trichomonas vaginalis	tubulin, putative	0.0092	0.0049	0.0088
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Loa Loa (eye worm)	subtilase	0.0179	0.0286	0.0282
Echinococcus granulosus	Tubulin beta 2C chain	0.0092	0.0049	0.0045
Loa Loa (eye worm)	hypothetical protein	0.0179	0.0286	0.0282
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0253	0.0486	0.0878
Echinococcus multilocularis	neuropeptide receptor	0.0225	0.0411	0.0522
Schistosoma mansoni	retinoblastoma binding protein	0.008	0.0016	0.0013
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Brugia malayi	Will die slowly protein	0.014	0.018	0.0176
Loa Loa (eye worm)	hypothetical protein	0.0293	0.0595	0.0592
Echinococcus multilocularis	proprotein convertase subtilisin:kexin type 5	0.2112	0.5538	0.7099
Trichomonas vaginalis	hypothetical protein	0.081	0.2	0.3612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Schistosoma mansoni	site-1 peptidase (S08 family)	0.0179	0.0286	0.0282
Trichomonas vaginalis	conserved hypothetical protein	0.0179	0.0286	0.0516
Echinococcus granulosus	protein will die slowly	0.014	0.018	0.0176
Toxoplasma gondii	subtilisin SUB1	0.0179	0.0286	0.7496
Leishmania major	hypothetical protein, conserved	0.0097	0.0063	0.0604
Loa Loa (eye worm)	BEN-1 protein	0.0092	0.0049	0.0045
Onchocerca volvulus		0.0116	0.0115	0.1926
Onchocerca volvulus		0.0075	0.0004	0.0057
Toxoplasma gondii	subtilisin SUB11	0.0179	0.0286	0.7496
Plasmodium falciparum	subtilisin-like protease 3	0.0179	0.0286	1
Loa Loa (eye worm)	hypothetical protein	0.0293	0.0595	0.0592
Schistosoma mansoni	hypothetical protein	0.014	0.018	0.0176
Onchocerca volvulus		0.0075	0.0004	0.0057
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1063	0.2687	0.4852
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3)	0.0179	0.0286	0.5
Brugia malayi	Hypothetical subtilase-type proteinase F21H12.6 in chromosome II	0.0179	0.0286	0.0282
Trypanosoma cruzi	subtilisin peptidase	0.0179	0.0286	1
Trichomonas vaginalis	leucine-rich repeat protein, BspA family	0.081	0.2	0.3612
Echinococcus granulosus	wd40 repeat	0.008	0.0016	0.0013
Onchocerca volvulus		0.0075	0.0004	0.0057
Loa Loa (eye worm)	endoprotease bli-4	0.3755	1	1
Echinococcus multilocularis		0.2945	0.7799	1
Onchocerca volvulus		0.0075	0.0004	0.0057
Brugia malayi	Furin-like cysteine rich region family protein	0.0387	0.085	0.0847
Echinococcus granulosus	membrane bound transcription factor site 1	0.0179	0.0286	0.0282
Echinococcus granulosus	peptidase s8 s53 subtilisin kexin sedolisin	0.0179	0.0286	0.0282
Echinococcus multilocularis	neuroendocrine convertase 2	0.2705	0.7149	0.9165
Toxoplasma gondii	subtilisin SUB8	0.0179	0.0286	0.7496
Entamoeba histolytica	tubulin family protein	0.0092	0.0049	0.5
Echinococcus granulosus	tubulin subunit beta	0.0092	0.0049	0.0045
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Mycobacterium tuberculosis	Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5)	0.0179	0.0286	0.5
Echinococcus granulosus	furin	0.3755	1	1
Schistosoma mansoni	hypothetical protein	0.0097	0.0063	0.0059
Loa Loa (eye worm)	hypothetical protein	0.008	0.0016	0.0013
Schistosoma mansoni	tyrosine kinase	0.0387	0.085	0.0847
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Trichomonas vaginalis	neuroendocrine convertase 2 precursor, putative	0.0884	0.2201	0.3974
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Brugia malayi	Hypothetical WD-repeat protein F21H12.1 in chromosome II	0.008	0.0016	0.0013
Echinococcus multilocularis	beta tubulin	0.0092	0.0049	0.0058
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Brugia malayi	Protein kinase domain containing protein	0.0097	0.0063	0.0059
Echinococcus granulosus	neuroendocrine convertase 2	0.2705	0.7149	0.7148
Echinococcus granulosus	Furin 1	0.1063	0.2687	0.2684
Trypanosoma cruzi	subtilisin-like serine peptidase, putative	0.0179	0.0286	1
Echinococcus multilocularis	Tubulin beta 2C chain	0.0092	0.0049	0.0058
Trypanosoma brucei	subtilisin peptidase	0.0179	0.0286	1
Trichomonas vaginalis	tubulin beta chain, putative	0.0092	0.0049	0.0088
Brugia malayi	beta-tubulin, identical	0.0092	0.0049	0.0045
Echinococcus granulosus	tubulin beta 1 chain	0.0092	0.0049	0.0045
Echinococcus granulosus	Tubulin beta 2C chain	0.0092	0.0049	0.0045
Loa Loa (eye worm)	proprotein convertase 2	0.1063	0.2687	0.2684
Toxoplasma gondii	subtilisin SUB2	0.0179	0.0286	0.7496
Plasmodium vivax	subtilisin-like protease 2, putative	0.0179	0.0286	1
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0075	0.0004	0.0057
Echinococcus granulosus	neuropeptide receptor	0.0225	0.0411	0.0407
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1063	0.2687	0.4852
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	conserved hypothetical protein	0.008	0.0016	0.0029
Brugia malayi	Trypsin family protein	0.0293	0.0595	0.0592
Mycobacterium tuberculosis	Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4)	0.0179	0.0286	0.5
Schistosoma mansoni	tubulin subunit beta	0.0092	0.0049	0.0045
Schistosoma mansoni	tubulin subunit beta	0.0092	0.0049	0.0045
Plasmodium falciparum	subtilisin-like protease 1	0.0179	0.0286	1
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1063	0.2687	0.4852
Echinococcus multilocularis	Tubulin beta 2C chain	0.0092	0.0049	0.0058
Schistosoma mansoni	subfamily S8B unassigned peptidase (S08 family)	0.0253	0.0486	0.0483
Echinococcus multilocularis	aminopeptidase N	0.0116	0.0115	0.0143
Echinococcus granulosus	aminopeptidase N	0.0116	0.0115	0.0111
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Echinococcus multilocularis	G protein coupled receptor 139	0.0225	0.0411	0.0522
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0075	0.0004	0.0057
Schistosoma mansoni	tubulin subunit beta	0.0092	0.0049	0.0045
Mycobacterium ulcerans	membrane-anchored mycosin MycP3	0.0179	0.0286	0.5
Schistosoma mansoni	subfamily S8B non-peptidase homologue (S08 family)	0.1063	0.2687	0.2684
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1063	0.2687	0.4852
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Onchocerca volvulus		0.0179	0.0286	0.4802
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	conserved hypothetical protein	0.0179	0.0286	0.0516
Onchocerca volvulus		0.0075	0.0004	0.0057
Loa Loa (eye worm)	hypothetical protein	0.1716	0.4462	0.446
Echinococcus multilocularis	tissue type plasminogen activator	0.0097	0.0063	0.0076
Loa Loa (eye worm)	tubulin beta-4 chain	0.0092	0.0049	0.0045
Trichomonas vaginalis	tubulin gamma chain, putative	0.0092	0.0049	0.0088
Trypanosoma cruzi	serine peptidase, clan SB, family S8-like protein	0.0179	0.0286	1
Loa Loa (eye worm)	BEN-1 protein	0.0092	0.0049	0.0045
Mycobacterium leprae	Possible secreted protease	0.0179	0.0286	0.5
Onchocerca volvulus		0.0097	0.0063	0.1053
Loa Loa (eye worm)	TK/ROR protein kinase	0.0097	0.0063	0.0059
Trichomonas vaginalis	tubulin epsilon chain, putative	0.0092	0.0049	0.0088
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trypanosoma brucei	serine peptidase, clan SB, family S8-like protein	0.0179	0.0286	1
Trichomonas vaginalis	conserved hypothetical protein	0.081	0.2	0.3612
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.1063	0.2687	0.4852
Echinococcus multilocularis	protein will die slowly	0.014	0.018	0.0226
Plasmodium vivax	subtilisin-like protease 1	0.0179	0.0286	1
Loa Loa (eye worm)	tubulin beta-2A chain	0.0092	0.0049	0.0045
Onchocerca volvulus		0.0075	0.0004	0.0057
Onchocerca volvulus		0.0075	0.0004	0.0057
Loa Loa (eye worm)	hypothetical protein	0.0082	0.0022	0.0018
Schistosoma mansoni	hypothetical protein	0.081	0.2	0.1997
Onchocerca volvulus		0.014	0.018	0.3022
Schistosoma mansoni	tubulin subunit beta	0.0092	0.0049	0.0045
Toxoplasma gondii	subtilisin SUB12	0.0208	0.0365	1
Mycobacterium leprae	PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5)	0.0179	0.0286	0.5
Trichomonas vaginalis	retinoblastoma binding protein, putative	0.008	0.0016	0.0029
Echinococcus multilocularis	Tubulin beta 2C chain	0.0092	0.0049	0.0058
Schistosoma mansoni	tubulin subunit beta	0.0092	0.0049	0.0045
Echinococcus multilocularis	Tubulin beta 2C chain	0.0092	0.0049	0.0058
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0293	0.0595	0.0592
Brugia malayi	proprotein convertase 2	0.2705	0.7149	0.7148
Giardia lamblia	High cysteine membrane protein Group 2	0.1123	0.2851	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.0294	0.0598	0.0594
Brugia malayi	Peptidase family M1 containing protein	0.0116	0.0115	0.0111
Trichomonas vaginalis	Clan SB, family S8, subtilisin-like serine peptidase	0.0179	0.0286	0.0516
Giardia lamblia	Furin precursor putative serine protease	0.0884	0.2201	0.7678
Loa Loa (eye worm)	WD40 repeat protein	0.014	0.018	0.0176
Echinococcus multilocularis	beta tubulin	0.0092	0.0049	0.0058
Trichomonas vaginalis	conserved hypothetical protein	0.0179	0.0286	0.0516
Echinococcus granulosus	Tubulin beta 2C chain	0.0092	0.0049	0.0045
Loa Loa (eye worm)	hypothetical protein	0.054	0.1266	0.1263

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 912008