Detailed information for compound 91212

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 335.482 | Formula: C23H29NO
  • H donors: 1 H acceptors: 1 LogP: 5.26 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1cccc(c1)[C@@]1(C)CCN(C[C@@H]1C)CC1C[C@@H]1c1ccccc1
  • InChi: 1S/C23H29NO/c1-17-15-24(16-19-13-22(19)18-7-4-3-5-8-18)12-11-23(17,2)20-9-6-10-21(25)14-20/h3-10,14,17,19,22,25H,11-13,15-16H2,1-2H3/t17-,19?,22+,23+/m0/s1
  • InChiKey: ZBKMHZDNQWQSNM-JREXYYMMSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0188 0.0188
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0411 0.0877
Echinococcus multilocularis allatostatin A receptor 0.0021 0.0045 0.0045
Echinococcus granulosus g protein coupled receptor 0.0021 0.0045 0.0045
Echinococcus granulosus smad 0.0024 0.0076 0.0076
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0021 0.0045 0.0097
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0127 0.0381
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0045 0.0066
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0021 0.0045 0.0097
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0127 0.5
Loa Loa (eye worm) hypothetical protein 0.0033 0.0172 0.0366
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0057 0.0411 0.1726
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0411 0.0595
Echinococcus granulosus G protein coupled receptor 139 0.0021 0.0045 0.0045
Trichomonas vaginalis set domain proteins, putative 0.0232 0.2183 0.9164
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0411 0.1726
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0029 0.0129 0.0542
Brugia malayi larval opioid receptor 0.0021 0.0045 0.0097
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0188 0.0188
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0021 0.0045 0.0097
Plasmodium vivax unspecified product 0.0079 0.0632 0.2535
Brugia malayi Bromodomain containing protein 0.0041 0.0248 0.0529
Trichomonas vaginalis ferritin, putative 0.0017 0 0.0001
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0057 0.0411 0.1593
Loa Loa (eye worm) heterochromatin protein 1 0.008 0.0641 0.1368
Brugia malayi Papain family cysteine protease containing protein 0.0136 0.121 0.2582
Loa Loa (eye worm) hypothetical protein 0.0043 0.0272 0.058
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0252 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0241 0.0865
Trypanosoma cruzi target of rapamycin kinase 3 0.0069 0.0536 0.1144
Loa Loa (eye worm) hypothetical protein 0.0057 0.0411 0.0877
Schistosoma mansoni neuropeptide receptor 0.0021 0.0045 0.0066
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0029 0.0127 0.0526
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus peptide allatostatin:somatostatin 0.0021 0.0045 0.0045
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0045 0.0045
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0045 0.0045
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0087 0.0716 0.0716
Onchocerca volvulus 0.0028 0.012 0.0321
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0041 0.0251 0.1052
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0903 0.1927
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0021 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0041
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0021 0.0045 0.0045
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Schistosoma mansoni neuropeptide f receptor 76f 0.0021 0.0045 0.0066
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0047 0.031 0.031
Echinococcus multilocularis sex peptide receptor 0.0021 0.0045 0.0045
Trypanosoma cruzi cysteine peptidase, putative 0.0252 0.2382 0.5082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0479 0.4687 0.6781
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0057 0.0411 0.1593
Loa Loa (eye worm) hypothetical protein 0.0173 0.1583 0.3377
Schistosoma mansoni amine GPCR 0.0021 0.0045 0.0066
Echinococcus granulosus cathepsin b 0.0479 0.4687 0.4687
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0057 0.0411 0.1593
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0411 0.0595
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0301 0.1123
Echinococcus granulosus cpg binding protein 0.0032 0.0155 0.0155
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0045 0.0045
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Loa Loa (eye worm) ctsf protein 0.0252 0.2382 0.5082
Onchocerca volvulus Cathepsin L homolog 0.0057 0.0411 0.1566
Schistosoma mansoni cpg binding protein 0.0032 0.0155 0.0225
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0001 0.0001
Brugia malayi CXXC zinc finger family protein 0.0028 0.012 0.0257
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0286 0.103
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0221 0.2067 0.2067
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0152 0.1368 0.1979
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.1298 0.1298
Trypanosoma cruzi cysteine proteinase, putative 0.0136 0.121 0.2582
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0411 0.1726
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0045 0.0045
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0479 0.4687 1
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0921 0.3867
Trichomonas vaginalis chromobox protein, putative 0.008 0.0641 0.2692
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0057 0.0411 0.1726
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0045 0.0066
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0127 0.0533
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0411 0.1726
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0535 0.2247
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0921 0.3867
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Trypanosoma cruzi cruzipain precursor, putative 0.0252 0.2382 0.5082
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Brugia malayi GnHR receptor homolog 0.0021 0.0045 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0127
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0057 0.0411 0.2202
Schistosoma mansoni hypothetical protein 0.0182 0.1678 0.2427
Schistosoma mansoni biogenic amine receptor 0.0021 0.0045 0.0066
Echinococcus multilocularis cpg binding protein 0.0032 0.0155 0.0155
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0127 0.0381
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0921 0.3867
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus neuropeptide receptor A26 0.0021 0.0045 0.0045
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Echinococcus multilocularis GPCR, family 2 0.0033 0.0172 0.0172
Entamoeba histolytica hypothetical protein 0.0221 0.2067 0.8678
Echinococcus granulosus sex peptide receptor 0.0021 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0057 0.0411 0.1726
Schistosoma mansoni hypothetical protein 0.0047 0.031 0.0449
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0087 0.0716 0.0716
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0087 0.0716 0.2893
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0929 0.924 0.924
Loa Loa (eye worm) hypothetical protein 0.0079 0.0632 0.1348
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0136 0.121 0.1751
Brugia malayi Melatonin receptor type 1A 0.0021 0.0045 0.0097
Schistosoma mansoni hypothetical protein 0.0033 0.0172 0.0248
Leishmania major ATP-dependent phosphofructokinase 0.0107 0.0921 0.3768
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Brugia malayi follicle stimulating hormone receptor 0.0021 0.0045 0.0097
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0303 0.0438
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Giardia lamblia Cathepsin B precursor 0.0188 0.1734 1
Echinococcus granulosus orexin receptor type 2 0.0021 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0411 0.1726
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0309 0.1298
Schistosoma mansoni chromobox protein 0.008 0.0641 0.0928
Entamoeba histolytica cysteine proteinase, putative 0.0136 0.121 0.5081
Schistosoma mansoni neuropeptide receptor 0.0021 0.0045 0.0066
Plasmodium vivax 6-phosphofructokinase, putative 0.0029 0.0127 0.0381
Loa Loa (eye worm) fibroinase 0.0252 0.2382 0.5082
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0921 0.1332
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0045 0.0097
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Schistosoma mansoni hypothetical protein 0.0021 0.0045 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Brugia malayi Serotonin receptor 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0716 0.3006
Schistosoma mansoni hypothetical protein 0.0033 0.0172 0.0248
Schistosoma mansoni hypothetical protein 0.0221 0.2067 0.299
Trichomonas vaginalis conserved hypothetical protein 0.0017 0 0.0001
Brugia malayi AKH receptor 0.0021 0.0045 0.0097
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0057 0.0411 0.2202
Echinococcus granulosus g-protein coupled receptor 0.0021 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus microtubule associated protein 2 0.0699 0.6913 0.6913
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Schistosoma mansoni cpg binding protein 0.0028 0.012 0.0174
Brugia malayi Cathepsin L-like precursor 0.0252 0.2382 0.5082
Echinococcus multilocularis microtubule associated protein 2 0.0699 0.6913 0.6913
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0045 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0411 0.1726
Brugia malayi Heterochromatin protein 1 0.008 0.0641 0.1368
Echinococcus multilocularis fmrfamide receptor 0.0021 0.0045 0.0045
Brugia malayi G-protein coupled receptor 0.0021 0.0045 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0127
Schistosoma mansoni transcription factor LCR-F1 0.0221 0.2067 0.299
Toxoplasma gondii cathepsin CPC1 0.0057 0.0411 0.1726
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0021 0.0045 0.0045
Brugia malayi putative neuropeptide receptor 0.0021 0.0045 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0411 0.1726
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0087 0.0716 0.3006
Schistosoma mansoni amine GPCR 0.0021 0.0045 0.0066
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0127
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0045 0.0045
Brugia malayi cathepsin Z-like cysteine proteinase 0.0057 0.0411 0.0877
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0301 0.1263
Brugia malayi Cathepsin L-like precursor 0.0173 0.1583 0.3377
Schistosoma mansoni hypothetical protein 0.0021 0.0045 0.0066
Loa Loa (eye worm) Smad1 0.0024 0.0076 0.0161
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0252 0.2382 1
Schistosoma mansoni neuropeptide receptor 0.0021 0.0045 0.0066
Echinococcus granulosus 7tm_1 domain containing protein 0.0021 0.0045 0.0045
Echinococcus multilocularis G-protein coupled receptor, putative 0.0021 0.0045 0.0045
Leishmania major phosphatidylinositol 3-kinase, putative 0.0029 0.0129 0.039
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0309 0.1298
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0479 0.4687 0.6781
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0057 0.0411 0.0595
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0045 0.0045
Schistosoma mansoni smad 0.0024 0.0076 0.0109
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0301 0.1263
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0117 0.0117
Giardia lamblia Cathepsin L precursor 0.0057 0.0411 0.2202
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Giardia lamblia Cathepsin L-like protease 0.0057 0.0411 0.2202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0173 0.1583 0.6646
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0029 0.0127 0.0533
Schistosoma mansoni smad1 5 8 and 0.0024 0.0076 0.0109
Loa Loa (eye worm) hypothetical protein 0.0105 0.0897 0.1915
Plasmodium falciparum serine repeat antigen 7 0.0057 0.0411 0.1593
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.049 0.2056
Loa Loa (eye worm) hypothetical protein 0.0147 0.1321 0.2819
Schistosoma mansoni myosin xvIII 0.0021 0.0045 0.0066
Onchocerca volvulus 0.0252 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0057 0.0411 0.1726
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0021 0.0045 0.0066
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0038 0.0081
Brugia malayi Cathepsin L-like precursor 0.0252 0.2382 0.5082
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0252 0.2382 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0069 0.0536 0.2126
Echinococcus granulosus cysteine protease 0.0136 0.121 0.121
Schistosoma mansoni amine GPCR 0.0021 0.0045 0.0066
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0057 0.0411 0.0877
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0449 0.1883
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0411 0.0877
Plasmodium vivax vivapain-2 0.0252 0.2382 1
Brugia malayi MH2 domain containing protein 0.0024 0.0076 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0411 0.1726
Echinococcus multilocularis zinc finger protein 0.0024 0.008 0.008
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0135 0.0565
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0038 0.0081
Plasmodium falciparum serine repeat antigen 1 0.0057 0.0411 0.1593
Toxoplasma gondii 6-phosphofructokinase 0.0029 0.0127 0.0533
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0038 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0172 0.0172
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0021 0.0045 0.0045
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0021 0.0045 0.0097
Schistosoma mansoni smad1 5 8 and 0.0024 0.0076 0.0109
Echinococcus multilocularis cathepsin L 0.0057 0.0411 0.0411
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0921 0.3867
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0716 0.3006
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0145 0.1298 0.1298
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus multilocularis neuropeptides capa receptor 0.0021 0.0045 0.0045
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0252 0.2382 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0921 0.1965
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0057 0.0411 0.1593
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0021 0.0045 0.0097
Echinococcus multilocularis dro:myosuppressin receptor 0.0021 0.0045 0.0045
Echinococcus multilocularis neuropeptide Y receptor 0.0021 0.0045 0.0045
Schistosoma mansoni ap endonuclease 0.002 0.0038 0.0055
Trypanosoma cruzi PAB1-binding protein , putative 0.0105 0.0897 0.1915
Echinococcus multilocularis chromobox protein 1 0.008 0.0641 0.0641
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0038 0.0158
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Plasmodium falciparum serine repeat antigen 3 0.0057 0.0411 0.1593
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0087 0.0716 0.1528
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0057 0.0411 0.1593
Giardia lamblia Cathepsin B precursor 0.0057 0.0411 0.2202
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0045 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Echinococcus granulosus chromobox protein 1 0.008 0.0641 0.0641
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0286 0.1201
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0021 0.0045 0.0066
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0029 0.0129 0.0275
Echinococcus granulosus g protein coupled receptor 0.0021 0.0045 0.0045
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0076 0.0161
Loa Loa (eye worm) hypothetical protein 0.0057 0.0411 0.0877
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0045 0.0045
Entamoeba histolytica cysteine proteinase 2 0.0136 0.121 0.5081
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0057 0.0411 0.0877
Brugia malayi 6-phosphofructokinase 0.0107 0.0921 0.1965
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0057 0.0411 0.0595
Plasmodium vivax SET domain protein, putative 0.003 0.0135 0.0413
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0476 0.0476
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Plasmodium falciparum serine repeat antigen 6 0.0057 0.0411 0.1593
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0411 0.0877
Schistosoma mansoni cpg binding protein 0.0032 0.0155 0.0225
Echinococcus multilocularis cathepsin b 0.0479 0.4687 0.4687
Onchocerca volvulus 0.0057 0.0411 0.1566
Echinococcus granulosus biogenic amine 5HT receptor 0.0021 0.0045 0.0045
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0172 0.0366
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0535 0.2247
Echinococcus multilocularis neuropeptide receptor A26 0.0021 0.0045 0.0045
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0087 0.0716 0.3006
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0303 0.0303
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0411 0.1726
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0127
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Plasmodium vivax vivapain-1 0.0136 0.121 0.5001
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0921 0.3867
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Brugia malayi latrophilin 2 splice variant baaae 0.0072 0.0565 0.1205
Toxoplasma gondii cathepsin CPC2 0.0057 0.0411 0.1726
Loa Loa (eye worm) cysteine protease 0.0252 0.2382 0.5082
Brugia malayi Papain family cysteine protease containing protein 0.0252 0.2382 0.5082
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.049 0.2056
Schistosoma mansoni hypothetical protein 0.0033 0.0172 0.0248
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0045 0.0066
Giardia lamblia Cathepsin B precursor 0.0057 0.0411 0.2202
Brugia malayi cathepsin L-like precursor 0.0173 0.1583 0.3377
Loa Loa (eye worm) phosphofructokinase 0.0107 0.0921 0.1965
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Giardia lamblia Cathepsin L precursor 0.0057 0.0411 0.2202
Echinococcus multilocularis somatostatin receptor 0.0021 0.0045 0.0045
Entamoeba histolytica cysteine proteinase, putative 0.0173 0.1583 0.6646
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0038 0.0407
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0252 0.2382 0.2382
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Entamoeba histolytica cysteine proteinase, putative 0.0252 0.2382 1
Echinococcus granulosus neuropeptide receptor 0.0021 0.0045 0.0045
Trichomonas vaginalis chromobox protein, putative 0.0048 0.032 0.1345
Loa Loa (eye worm) hypothetical protein 0.0079 0.0632 0.1348
Echinococcus granulosus cathepsin b 0.0479 0.4687 0.4687
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Plasmodium falciparum cysteine proteinase falcipain 1 0.0136 0.121 0.5001
Leishmania major hypothetical protein, conserved 0.0105 0.0897 0.3667
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.049 0.2056
Brugia malayi MH2 domain containing protein 0.0352 0.3394 0.7241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0535 0.2247
Trichomonas vaginalis chromobox protein, putative 0.008 0.0641 0.2692
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Giardia lamblia Cysteine protease 0.0057 0.0411 0.2202
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0411 0.1726
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0021 0.0045 0.0045
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0072 0.0072
Plasmodium vivax vivapain-3 0.0136 0.121 0.5001
Echinococcus multilocularis cathepsin L cysteine protease 0.0252 0.2382 0.2382
Plasmodium vivax ataxin-2 like protein, putative 0.0105 0.0897 0.3667
Schistosoma mansoni cellular tumor antigen P53 0.0147 0.1321 0.1911
Toxoplasma gondii phosphofructokinase PFKII 0.0029 0.0127 0.0533
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0136 0.121 0.1751
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0045 0.0045
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.049 0.2056
Schistosoma mansoni bromodomain containing protein 0.0067 0.0511 0.0739
Giardia lamblia Hypothetical protein 0.0057 0.0411 0.2202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.121 0.5081
Brugia malayi acetyltransferase, GNAT family protein 0.0152 0.1368 0.2919
Echinococcus granulosus cathepsin L cysteine protease 0.0136 0.121 0.121
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0076 0.0076
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0029 0.0129 0.039
Echinococcus multilocularis G protein coupled receptor 139 0.0021 0.0045 0.0045
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0903 0.1927
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.003 0.0127
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Brugia malayi Cathepsin L-like precursor 0.0252 0.2382 0.5082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0087 0.0716 0.3006
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0021 0.0045 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0074 0.0587 0.2464
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0129 0.0542
Entamoeba histolytica cysteine protease, putative 0.0057 0.0411 0.1726
Schistosoma mansoni hypothetical protein 0.0182 0.1678 0.2427
Echinococcus multilocularis neuropeptide receptor 0.0021 0.0045 0.0045
Entamoeba histolytica phosphofructokinase, putative 0.0107 0.0921 0.3867
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.008
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0029 0.0127 0.0381
Echinococcus multilocularis cathepsin L cysteine protease 0.0252 0.2382 0.2382
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0029 0.0129 0.0542
Echinococcus granulosus neuropeptide s receptor 0.0021 0.0045 0.0045
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0001 0.0001
Trichomonas vaginalis chromobox protein, putative 0.0048 0.032 0.1345
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.031 0.1301
Toxoplasma gondii exonuclease III APE 0.002 0.0038 0.0158
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0079 0.0632 0.1348
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.031 0.1301
Giardia lamblia Cathepsin B precursor 0.0188 0.1734 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0286 0.061
Loa Loa (eye worm) hypothetical protein 0.0252 0.2382 0.5082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Echinococcus granulosus tm gpcr rhodopsin 0.0021 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0355 0.1492
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0072 0.0104
Brugia malayi 6-phosphofructokinase 0.0107 0.0921 0.1965
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0361 0.1514
Mycobacterium ulcerans 6-phosphofructokinase 0.0107 0.0921 1
Brugia malayi neuropeptide F receptor 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0355 0.1492
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0301 0.1263
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0921 0.3867
Plasmodium falciparum serine repeat antigen 2 0.0057 0.0411 0.1593
Echinococcus multilocularis 6 phosphofructokinase 0.0107 0.0921 0.0921
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Schistosoma mansoni cathepsin F (C01 family) 0.0252 0.2382 0.3446
Onchocerca volvulus Cathepsin L homolog 0.0252 0.2382 1
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0154 0.0646
Schistosoma mansoni alpha-1 adrenergic receptor 0.0021 0.0045 0.0066
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0038 0.0038
Echinococcus multilocularis tumor protein p63 0.1004 1 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus Smad4 0.0024 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0021 0.0045 0.0097
Schistosoma mansoni chromobox protein 0.008 0.0641 0.0928
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0252 0.2382 0.5082
Brugia malayi phosphofructokinase 0.0107 0.0921 0.1965
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.1298 0.1878
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0047 0.031 0.031
Echinococcus granulosus somatostatin receptor 0.0021 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0404 0.3924 0.5677
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0029 0.0127 0.1375
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0301 0.1263
Echinococcus granulosus cathepsin L 0.0057 0.0411 0.0411
Brugia malayi cathepsin F-like cysteine proteinase 0.0057 0.0411 0.0877
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0411 0.1726
Brugia malayi G protein-coupled receptor 0.0021 0.0045 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.121 0.5081
Echinococcus multilocularis cathepsin b 0.0479 0.4687 0.4687
Trichomonas vaginalis PIKK family atypical protein kinase 0.0057 0.0406 0.1705
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0045 0.0066
Brugia malayi Pre-SET motif family protein 0.0204 0.1898 0.405
Loa Loa (eye worm) hypothetical protein 0.0057 0.0411 0.0877
Schistosoma mansoni cathepsin S (C01 family) 0.0057 0.0411 0.0595
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0411 0.0877
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0038 0.0158
Echinococcus granulosus cathepsin l cysteine peptidase 0.0252 0.2382 0.2382
Brugia malayi Tachykinin-like peptides receptor 99D 0.0021 0.0045 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Schistosoma mansoni smad1 5 8 and 0.0024 0.0076 0.0109
Plasmodium falciparum ataxin-2 like protein, putative 0.0105 0.0897 0.3667
Brugia malayi cathepsin L-like cysteine proteinase 0.0057 0.0411 0.0877
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0127
Brugia malayi RE15519p 0.0021 0.0045 0.0097
Echinococcus multilocularis cathepsin L 0.0136 0.121 0.121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.0173 0.1583 0.3377
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.1298 0.1298
Schistosoma mansoni opsin-like receptor 0.0021 0.0045 0.0066
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0038 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.007 0.0293
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0057 0.0411 0.0595
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.031 0.1301
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Echinococcus granulosus neuropeptide FF receptor 2 0.0021 0.0045 0.0045
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0057 0.0411 0.1593
Echinococcus granulosus alpha 1A adrenergic receptor 0.0021 0.0045 0.0045
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0021 0.0045 0.0097
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0303 0.0303
Giardia lamblia Hypothetical protein 0.0057 0.0411 0.2202
Echinococcus granulosus neuropeptide Y receptor 0.0021 0.0045 0.0045
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0029 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0172 0.0366
Schistosoma mansoni adenoreceptor 0.0021 0.0045 0.0066
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus fmrfamide receptor 0.0021 0.0045 0.0045
Echinococcus granulosus GPCR family 2 0.0033 0.0172 0.0172
Loa Loa (eye worm) transcription factor SMAD2 0.0352 0.3394 0.7241
Toxoplasma gondii target of rapamycin (TOR), putative 0.0065 0.049 0.2056
Loa Loa (eye worm) hypothetical protein 0.0079 0.0632 0.1348
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Schistosoma mansoni zinc finger protein 0.0024 0.008 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0057 0.0411 0.1726
Brugia malayi hypothetical protein 0.0221 0.2067 0.441
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0107 0.0921 0.1965
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0079 0.0632 0.1348
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0057 0.0411 0.1593
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0038 0.0081
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0145 0.1298 0.277
Brugia malayi Bromodomain containing protein 0.0078 0.0626 0.1337
Echinococcus granulosus 6 phosphofructokinase 0.0107 0.0921 0.0921
Brugia malayi cathepsin Z-like cysteine proteinase 0.0057 0.0411 0.0877
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0107 0.0921 1
Echinococcus granulosus serotonin receptor 0.0021 0.0045 0.0045
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Brugia malayi Papain family cysteine protease containing protein 0.0057 0.0411 0.0877
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Schistosoma mansoni cathepsin B (C01 family) 0.0057 0.0411 0.0595
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0188 0.1734 0.3699
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0021 0.0045 0.0097
Schistosoma mansoni biogenic amine receptor 0.0021 0.0045 0.0066
Echinococcus granulosus neuropeptide receptor 0.0021 0.0045 0.0045
Toxoplasma gondii cathepsin B 0.0188 0.1734 0.7279
Schistosoma mansoni neuropeptide receptor 0.0021 0.0045 0.0066
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0002
Onchocerca volvulus 0.0035 0.0188 0.0611
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.121 0.5081
Giardia lamblia GTOR 0.0087 0.0716 0.3999
Loa Loa (eye worm) neuropeptide F receptor 0.0021 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0046 0.0303 0.0646
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0021 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.002 0.0037 0.0053
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0136 0.121 0.2582
Entamoeba histolytica cysteine protease, putative 0.0057 0.0411 0.1726
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0241 0.1196
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.121 0.2582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0361 0.1514
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0145 0.1298 0.1298
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0018 0.0013 0.0028
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.003 0.0127
Loa Loa (eye worm) hypothetical protein 0.0072 0.0565 0.1205
Echinococcus granulosus allatostatin A receptor 0.0021 0.0045 0.0045
Brugia malayi Cathepsin L-like precursor 0.0252 0.2382 0.5082
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0172 0.0172
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0001 0.0001
Trypanosoma cruzi cruzipain precursor, putative 0.0079 0.0632 0.1348
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0057 0.0411 0.1593
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0038 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Giardia lamblia Cathepsin B precursor 0.0057 0.0411 0.2202
Brugia malayi PHD-finger family protein 0.003 0.0132 0.0282
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Plasmodium falciparum serine repeat antigen 5 0.0057 0.0411 0.1593
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0021 0.0045 0.0045
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0029 0.0129 0.0275
Brugia malayi Cathepsin L-like precursor 0.0252 0.2382 0.5082
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0021 0.0045 0.0097
Brugia malayi Dopamine receptor 0.0021 0.0045 0.0097
Giardia lamblia Cathepsin B precursor 0.0188 0.1734 1
Giardia lamblia Cysteine protease 0.0057 0.0411 0.2202
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0048 0.032 0.1177
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0057 0.0411 0.1593
Brugia malayi Cathepsin L-like cysteine proteinase 0.0173 0.1583 0.3377
Echinococcus granulosus zinc finger protein 0.0024 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0135 0.0135
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Echinococcus multilocularis serotonin receptor 0.0021 0.0045 0.0045
Brugia malayi ORL1-like opioid receptor 0.0021 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Onchocerca volvulus 0.0043 0.0267 0.0948
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus cathepsin l1 0.0173 0.1583 0.1583
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0127 0.0533
Toxoplasma gondii cathepsin CPL 0.0252 0.2382 1
Brugia malayi Cathepsin L-like precursor 0.0173 0.1583 0.3377
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0301 0.0301
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0076 0.0109
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0188 0.1734 0.7279
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0188 0.1734 0.2508
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0087 0.0716 0.1528
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0076 0.0161
Loa Loa (eye worm) hypothetical protein 0.0479 0.4687 1
Trypanosoma cruzi cysteine protease, putative 0.0136 0.121 0.2582
Trypanosoma cruzi cysteine peptidase, putative 0.0252 0.2382 0.5082
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0145 0.1298 0.277
Echinococcus multilocularis neuropeptide s receptor 0.0021 0.0045 0.0045
Echinococcus granulosus dro:myosuppressin receptor 0.0021 0.0045 0.0045
Loa Loa (eye worm) cathepsin B 0.0188 0.1734 0.3699
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0021 0.0045 0.0045
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0045 0.0045
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0021 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Schistosoma mansoni histamine h1 receptor 0.0021 0.0045 0.0066
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Schistosoma mansoni hypothetical protein 0.0021 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0173 0.1583 0.3377
Trypanosoma cruzi cysteine peptidase, putative 0.0252 0.2382 0.5082
Schistosoma mansoni cathepsin F (C01 family) 0.0173 0.1583 0.229
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0021 0.0045 0.0097
Entamoeba histolytica cysteine protease, putative 0.0252 0.2382 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0057 0.0411 0.1593
Plasmodium falciparum serine repeat antigen 8 0.0057 0.0411 0.1593
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0127 0.0533
Echinococcus granulosus neuropeptides capa receptor 0.0021 0.0045 0.0045
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0029 0.0129 0.0187
Brugia malayi cathepsin L precursor 0.0057 0.0411 0.0877
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0033 0.0172 0.0248
Brugia malayi chromobox protein homolog 3 0.0045 0.0286 0.061
Leishmania major cysteine peptidase A (CPA) 0.0252 0.2382 1
Brugia malayi CHD4 protein 0.0017 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0129 0.0542
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0029 0.0127 0.5
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Onchocerca volvulus 0.0252 0.2382 1
Entamoeba histolytica cysteine proteinase, putative 0.0252 0.2382 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0059 0.0425 0.1785
Plasmodium vivax unspecified product 0.0136 0.121 0.5001
Plasmodium falciparum serine repeat antigen 4 0.0057 0.0411 0.1593
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0107 0.0921 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0057 0.0411 0.1726
Trypanosoma cruzi PAB1-binding protein , putative 0.0105 0.0897 0.1915
Brugia malayi Cathepsin L-like precursor 0.0252 0.2382 0.5082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0411 0.0595
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus tachykinin peptides receptor 99D 0.0021 0.0045 0.0045
Echinococcus multilocularis cysteine protease 0.0252 0.2382 0.2382
Trypanosoma brucei cysteine peptidase C (CPC) 0.0188 0.1734 0.7279
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0136 0.121 0.5081
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Loa Loa (eye worm) MH2 domain-containing protein 0.0352 0.3394 0.7241
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0479 0.4687 0.6781
Schistosoma mansoni growth hormone secretagogue receptor 0.0021 0.0045 0.0066
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0072 0.0072
Trypanosoma brucei PAB1-binding protein , putative 0.0105 0.0897 0.3768
Entamoeba histolytica cysteine protease, putative 0.0057 0.0411 0.1726
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0076 0.0076
Entamoeba histolytica cysteine protease, putative 0.0057 0.0411 0.1726
Loa Loa (eye worm) hypothetical protein 0.0037 0.0212 0.0451
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0129 0.0542
Loa Loa (eye worm) bromodomain containing protein 0.0021 0.0044 0.0095
Plasmodium falciparum serine repeat antigen 9 0.0057 0.0411 0.1593
Toxoplasma gondii LsmAD domain-containing protein 0.0105 0.0897 0.3768
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0069 0.0536 0.225
Schistosoma mansoni cathepsin F (C01 family) 0.0252 0.2382 0.3446
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0136 0.121 0.1751
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Brugia malayi Cathepsin L-like precursor 0.0079 0.0632 0.1348
Brugia malayi putative neuropeptide receptor NPR1 0.0021 0.0045 0.0097
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0154 0.0646
Echinococcus granulosus cathepsin L cysteine proteinase 0.0252 0.2382 0.2382
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0411 0.1726
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0453 0.0656
Loa Loa (eye worm) TYRA-2 protein 0.0021 0.0045 0.0097
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0076 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0172 0.0172
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0411 0.0877
Entamoeba histolytica hypothetical protein 0.0221 0.2067 0.8678
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0173 0.1583 0.3377
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0087 0.0716 0.1528
Giardia lamblia Cathepsin L precursor 0.0057 0.0411 0.2202
Onchocerca volvulus 0.0252 0.2382 1
Echinococcus granulosus dnaJ subfamily B 0.0404 0.3924 0.3924
Schistosoma mansoni biogenic amine receptor 0.0021 0.0045 0.0066
Brugia malayi Dopamine receptor protein 1 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0052 0.0361 0.1514
Brugia malayi hypothetical protein 0.0068 0.052 0.111
Brugia malayi neuropeptide F receptor 0.0021 0.0045 0.0097
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Giardia lamblia Cathepsin B precursor 0.0057 0.0411 0.2202
Entamoeba histolytica cysteine proteinase, putative 0.0136 0.121 0.5081
Brugia malayi Dopamine receptor protein 2 0.0021 0.0045 0.0097
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0057 0.0411 0.1726
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus cathepsin l1 0.0252 0.2382 0.2382
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0021 0.0045 0.0045
Giardia lamblia Cysteine protease 0.0057 0.0411 0.2202
Brugia malayi hypothetical protein 0.0105 0.0897 0.1915
Onchocerca volvulus 0.0252 0.2382 1
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0127 0.0533
Brugia malayi cathepsin F-like cysteine proteinase 0.0079 0.0632 0.1348
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.1298 0.1878
Loa Loa (eye worm) hypothetical protein 0.0069 0.0531 0.1133
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Entamoeba histolytica cysteine protease, putative 0.0057 0.0411 0.1726
Giardia lamblia Cathepsin L-like protease 0.0057 0.0411 0.2202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0173 0.1583 0.6646
Brugia malayi hypothetical protein 0.0021 0.0045 0.0097
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0029 0.0127 0.0533
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0129 0.0542
Onchocerca volvulus Cathepsin L homolog 0.0252 0.2382 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0021 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Schistosoma mansoni hypothetical protein 0.0021 0.0045 0.0066
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0038 0.0407
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0001 0.0002
Schistosoma mansoni amine GPCR 0.0021 0.0045 0.0066
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0045 0.0097
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0152 0.1368 0.1368
Echinococcus granulosus hypothetical protein 0.0021 0.0045 0.0045
Schistosoma mansoni amine GPCR 0.0021 0.0045 0.0066
Brugia malayi MH1 domain containing protein 0.0024 0.0076 0.0161
Echinococcus multilocularis dnaJ subfamily B 0.0404 0.3924 0.3924
Loa Loa (eye worm) phosphatidylinositol 3 0.0029 0.0129 0.0275
Schistosoma mansoni Smad4 0.0024 0.0076 0.0109
Plasmodium vivax unspecified product 0.0057 0.0411 0.1593
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0057 0.0411 0.1726
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.1302 0.1302
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0646 0.6373 0.6373
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.003 0.0127
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0021 0.0045 0.0045
Echinococcus granulosus rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Giardia lamblia Cathepsin L precursor 0.0057 0.0411 0.2202
Loa Loa (eye worm) G-protein coupled receptor 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0309 0.1298
Loa Loa (eye worm) acetyltransferase 0.0152 0.1368 0.2919
Entamoeba histolytica cysteine proteinase, putative 0.0136 0.121 0.5081
Brugia malayi sulfakinin receptor protein 0.0021 0.0045 0.0097
Echinococcus granulosus 7TM GPCR rhodopsin 0.0021 0.0045 0.0045
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0057 0.0411 0.2202
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Brugia malayi Serotonin receptor 0.0021 0.0045 0.0097
Onchocerca volvulus 0.0252 0.2382 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0411 0.0595
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0107 0.0921 1
Entamoeba histolytica cysteine protease, putative 0.0057 0.0411 0.1726
Entamoeba histolytica hypothetical protein 0.0057 0.0411 0.1726
Giardia lamblia Encystation-specific protease 0.0057 0.0411 0.2202
Loa Loa (eye worm) hypothetical protein 0.0106 0.0903 0.1927
Toxoplasma gondii preprocathepsin c precursor, putative 0.0057 0.0411 0.1726
Schistosoma mansoni neuropeptide F-like receptor 0.0021 0.0045 0.0066
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0057 0.0411 0.0877
Schistosoma mansoni biogenic amine (5HT) receptor 0.0021 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0047 0.0307 0.0655
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0252 0.2382 1
Giardia lamblia Cathepsin L precursor 0.0057 0.0411 0.2202
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0021 0.0045 0.0045
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0252 0.2382 0.5082
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Schistosoma mansoni cathepsin s 0.0079 0.0632 0.0914
Leishmania major cathepsin L-like protease 0.0252 0.2382 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Brugia malayi MH1 domain containing protein 0.0024 0.0076 0.0161
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0057 0.0411 0.1726
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0535 0.2247
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0043 0.0267 0.0386
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0029 0.0129 0.0275
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0479 0.4687 0.6781
Plasmodium falciparum ataxin-2 like protein, putative 0.0105 0.0897 0.3667
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0476 0.0476
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0252 0.2382 0.2382
Echinococcus granulosus tm gpcr rhodopsin 0.0646 0.6373 0.6373
Giardia lamblia Cathepsin B precursor 0.0057 0.0411 0.2202
Brugia malayi MH2 domain containing protein 0.0024 0.0076 0.0161
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0076 0.0076
Plasmodium vivax serine-repeat antigen (SERA) 0.0057 0.0411 0.1593
Brugia malayi Papain family cysteine protease containing protein 0.0136 0.121 0.2582
Schistosoma mansoni microtubule-associated protein tau 0.0699 0.6913 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0021 0.0045 0.0066
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0021 0.0045 0.0045
Schistosoma mansoni fkbp-rapamycin associated protein 0.0016 0.00000001237 0.000000017895
Onchocerca volvulus 0.0252 0.2382 1
Entamoeba histolytica cysteine proteinase, putative 0.0136 0.121 0.5081
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0127 0.0533
Entamoeba histolytica hypothetical protein 0.0221 0.2067 0.8678
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0037 0.0078
Loa Loa (eye worm) hypothetical protein 0.0057 0.0411 0.0877
Loa Loa (eye worm) melatonin receptor type 1A 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.049 0.2056
Echinococcus granulosus g protein coupled receptor 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0232 0.2183 0.9148
Trichomonas vaginalis phosphofructokinase, putative 0.0107 0.0921 0.3867
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Brugia malayi Pre-SET motif family protein 0.003 0.0135 0.0287
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0188 0.1734 0.7235
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0057 0.0411 0.1593
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0021 0.0045 0.0066
Brugia malayi G protein-coupled receptor F59B2.13 0.0021 0.0045 0.0097
Plasmodium falciparum cysteine proteinase falcipain 3 0.0252 0.2382 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0057 0.0411 0.0595
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0021 0.0045 0.0045
Onchocerca volvulus Cathepsin F homolog 0.0252 0.2382 1
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0038 0.0158
Trypanosoma cruzi cysteine peptidase, putative 0.0252 0.2382 0.5082
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.031 0.1301
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0221 0.2067 0.2067
Onchocerca volvulus 0.0147 0.1321 0.546
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0303 0.0438
Loa Loa (eye worm) hypothetical protein 0.0057 0.0411 0.0877
Entamoeba histolytica hypothetical protein 0.0221 0.2067 0.8678
Brugia malayi Smad1 0.0024 0.0076 0.0161
Echinococcus multilocularis neuropeptide FF receptor 2 0.0021 0.0045 0.0045
Echinococcus multilocularis geminin 0.0182 0.1678 0.1678
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Brugia malayi G-protein coupled receptor 0.0021 0.0045 0.0097
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0036 0.02 0.0839
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0021 0.0045 0.0045
Echinococcus multilocularis Smad4 0.0024 0.0076 0.0076
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus granulosus chromobox protein 1 0.008 0.0641 0.0641
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0057 0.0411 0.1593
Echinococcus multilocularis g-protein coupled receptor 0.0021 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0129 0.0542
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.049 0.2056
Toxoplasma gondii non-specific serine/threonine protein kinase 0.0018 0.0019 0.008
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0087 0.0716 0.3006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus multilocularis smad 0.0024 0.0076 0.0076
Brugia malayi fibroinase precursor 0.0057 0.0411 0.0877
Brugia malayi cathepsin B-like cysteine proteinase 0.0479 0.4687 1
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0087 0.0716 0.3006
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0069 0.0535 0.2247
Entamoeba histolytica cysteine protease, putative 0.0136 0.121 0.5081
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0145 0.1298 0.1878
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0057 0.0411 0.2202
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0252 0.2382 1
Echinococcus multilocularis g protein coupled receptor 0.0021 0.0045 0.0045
Schistosoma mansoni ap endonuclease 0.002 0.0038 0.0055
Trichomonas vaginalis phosphofructokinase, putative 0.0029 0.0127 0.0533
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.1898 0.405
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0252 0.2382 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0903 0.1927
Giardia lamblia Cathepsin L precursor 0.0057 0.0411 0.2202
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0057 0.0411 0.0595
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0172 0.0366
Echinococcus multilocularis serotonin receptor 0.0021 0.0045 0.0045
Schistosoma mansoni cathepsin C 0.0057 0.0411 0.0595
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0241 0.101
Schistosoma mansoni opsin-like receptor 0.0021 0.0045 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0021 0.0045 0.0066
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Trypanosoma cruzi cysteine proteinase, putative 0.0136 0.121 0.2582
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0038 0.0407
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0087 0.0716 0.1036
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trypanosoma cruzi cysteine peptidase, putative 0.0079 0.0632 0.1348
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0087 0.0716 0.1528
Entamoeba histolytica cysteine proteinase 1, putative 0.0136 0.121 0.5081
Giardia lamblia Cysteine protease 0.0057 0.0411 0.2202
Echinococcus granulosus cathepsin L 0.0136 0.121 0.121
Loa Loa (eye worm) hypothetical protein 0.0057 0.0411 0.0877
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0172 0.0172
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0057 0.0411 0.1593
Plasmodium vivax vivapain-2 0.0252 0.2382 1
Loa Loa (eye worm) 6-phosphofructokinase 0.0107 0.0921 0.1965
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0087 0.0716 0.2893
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0286 0.1201
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0065 0.049 0.2056
Onchocerca volvulus 0.0173 0.1583 0.6581
Plasmodium vivax serine-repeat antigen (SERA) 0.0057 0.0411 0.1593
Schistosoma mansoni hypothetical protein 0.0072 0.0565 0.0817
Echinococcus multilocularis rhodopsin orphan GPCR 0.0021 0.0045 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0021 0.0045 0.0066
Echinococcus granulosus geminin 0.0182 0.1678 0.1678
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Schistosoma mansoni 6-phosphofructokinase 0.0107 0.0921 0.1332
Echinococcus multilocularis orexin receptor type 2 0.0021 0.0045 0.0045
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.012 0.0257
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0135 0.0195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Echinococcus multilocularis cysteine protease 0.0252 0.2382 0.2382
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0252 0.2382 1
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0029 0.0129 0.0129
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0021 0.0045 0.0066
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0021 0.0045 0.0066
Echinococcus multilocularis chromobox protein 1 0.008 0.0641 0.0641
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0057 0.0411 0.1726
Loa Loa (eye worm) hypothetical protein 0.0021 0.0045 0.0097
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0029 0.0127 0.0533
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0021 0.0045 0.0045
Schistosoma mansoni opsin-like receptor 0.0021 0.0045 0.0066
Loa Loa (eye worm) hypothetical protein 0.0035 0.0188 0.0401

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 56.1 nM Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 of rat brain membranes ChEMBL. 9599247
Ki (binding) = 388 nM Inhibition of [3H]U69,593 binding to Opioid receptor kappa 1 of guinea pig membranes ChEMBL. 9599247
Ki (binding) = 827 nM Inhibition of [3H]-DADLE binding to Opioid receptor delta 1 of rat brain membranes ChEMBL. 9599247

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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