Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.1134 | 0.4072 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1134 | 0.4072 | 0.4072 |
Giardia lamblia | Cathepsin B precursor | 0.0881 | 0.2752 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.078 | 0.2221 | 0.2221 |
Brugia malayi | Cathepsin L-like precursor | 0.1134 | 0.4072 | 0.4072 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Onchocerca volvulus | 0.1134 | 0.4072 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2269 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0614 | 0.1358 | 0.1358 |
Onchocerca volvulus | 0.1134 | 0.4072 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.078 | 0.2221 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.078 | 0.2221 | 0.3182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1134 | 0.4072 | 0.314 |
Onchocerca volvulus | 0.1134 | 0.4072 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0881 | 0.2752 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.1134 | 0.4072 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0881 | 0.2752 | 0.5139 |
Plasmodium vivax | vivapain-3 | 0.0614 | 0.1358 | 0.3334 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Echinococcus granulosus | cathepsin b | 0.2269 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.2221 | 0.2221 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1134 | 0.4072 | 0.314 |
Brugia malayi | Cathepsin L-like precursor | 0.1134 | 0.4072 | 0.4072 |
Onchocerca volvulus | 0.1134 | 0.4072 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Plasmodium vivax | vivapain-2 | 0.1134 | 0.4072 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0614 | 0.1358 | 0.1358 |
Onchocerca volvulus | 0.1134 | 0.4072 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1134 | 0.4072 | 0.314 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.078 | 0.2221 | 0.2221 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.2221 | 0.2221 |
Giardia lamblia | Cathepsin B precursor | 0.0881 | 0.2752 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.1134 | 0.4072 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1134 | 0.4072 | 0.4072 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1134 | 0.4072 | 0.314 |
Onchocerca volvulus | Cathepsin L homolog | 0.1134 | 0.4072 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1134 | 0.4072 | 0.4072 |
Echinococcus multilocularis | cysteine protease | 0.1134 | 0.4072 | 0.314 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1134 | 0.4072 | 0.4072 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0614 | 0.1358 | 0.1358 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1134 | 0.4072 | 0.4072 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1134 | 0.4072 | 0.314 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1134 | 0.4072 | 0.314 |
Trypanosoma cruzi | cysteine protease, putative | 0.0614 | 0.1358 | 0.1358 |
Brugia malayi | Cathepsin L-like precursor | 0.1134 | 0.4072 | 0.4072 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1134 | 0.4072 | 0.4072 |
Echinococcus multilocularis | cathepsin b | 0.2269 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2269 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0614 | 0.1358 | 0.1358 |
Toxoplasma gondii | cathepsin CPL | 0.1134 | 0.4072 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1134 | 0.4072 | 0.4072 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2269 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.1134 | 0.4072 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0881 | 0.2752 | 0.2752 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1134 | 0.4072 | 0.4072 |
Echinococcus granulosus | cathepsin l1 | 0.1134 | 0.4072 | 0.314 |
Onchocerca volvulus | 0.1134 | 0.4072 | 1 | |
Loa Loa (eye worm) | cathepsin B | 0.0881 | 0.2752 | 0.2752 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0614 | 0.1358 | 0.1358 |
Loa Loa (eye worm) | cysteine protease | 0.1134 | 0.4072 | 0.4072 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0881 | 0.2752 | 0.2752 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1134 | 0.4072 | 0.314 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Echinococcus granulosus | cathepsin b | 0.2269 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Plasmodium vivax | vivapain-1 | 0.0614 | 0.1358 | 0.3334 |
Loa Loa (eye worm) | ctsf protein | 0.1134 | 0.4072 | 0.4072 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0614 | 0.1358 | 0.1358 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0614 | 0.1358 | 0.1358 |
Loa Loa (eye worm) | hypothetical protein | 0.2269 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.078 | 0.2221 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1134 | 0.4072 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1134 | 0.4072 | 0.4072 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.078 | 0.2221 | 0.2221 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2269 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1134 | 0.4072 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0614 | 0.1358 | 0.1358 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1134 | 0.4072 | 0.4072 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Onchocerca volvulus | 0.1134 | 0.4072 | 1 | |
Brugia malayi | cathepsin L-like precursor | 0.078 | 0.2221 | 0.2221 |
Echinococcus granulosus | cathepsin l1 | 0.078 | 0.2221 | 0.0999 |
Echinococcus multilocularis | cathepsin b | 0.2269 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.078 | 0.2221 | 0.2221 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2269 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1134 | 0.4072 | 0.4072 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1134 | 0.4072 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.078 | 0.2221 | 0.2221 |
Brugia malayi | Cathepsin L-like precursor | 0.1134 | 0.4072 | 0.4072 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Plasmodium vivax | unspecified product | 0.0614 | 0.1358 | 0.3334 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1134 | 0.4072 | 0.4072 |
Onchocerca volvulus | Cathepsin F homolog | 0.1134 | 0.4072 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0881 | 0.2752 | 0.5139 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Leishmania major | cathepsin L-like protease | 0.1134 | 0.4072 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.078 | 0.2221 | 0.2221 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0614 | 0.1358 | 0.1358 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1134 | 0.4072 | 0.4072 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1134 | 0.4072 | 0.4072 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1134 | 0.4072 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.